ES8602732A1 - Procedimiento de preparacion del hidrocloruro de 1-(2-(5-dimetilaminometil-2-(furilmetiltio)-etil)-amino-1-metilamino-2-nitroetileno - Google Patents

Procedimiento de preparacion del hidrocloruro de 1-(2-(5-dimetilaminometil-2-(furilmetiltio)-etil)-amino-1-metilamino-2-nitroetileno

Info

Publication number
ES8602732A1
ES8602732A1 ES534363A ES534363A ES8602732A1 ES 8602732 A1 ES8602732 A1 ES 8602732A1 ES 534363 A ES534363 A ES 534363A ES 534363 A ES534363 A ES 534363A ES 8602732 A1 ES8602732 A1 ES 8602732A1
Authority
ES
Spain
Prior art keywords
nitroethylene
translation
procedure
preparation
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES534363A
Other languages
English (en)
Other versions
ES534363A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU251583A external-priority patent/HU193497B/hu
Priority claimed from HU251483A external-priority patent/HU193496B/hu
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES534363A0 publication Critical patent/ES534363A0/es
Publication of ES8602732A1 publication Critical patent/ES8602732A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DEL COMPUESTO DE FORMULA (I). CONSISTENTE EN HACER REACCIONAR EL MONOHIDROCLORURO DEL COMPUESTO DE FORMULA (II) CON EL NITROETILENO SUSTITUIDO DE FORMULA (III), OPTATIVAMENTE EN PRESENCIA DE AGUA Y/O DE UN DISOLVENTE ORGANICO A UNA TEMPERATURA COMPRENDIDA ENTRE 20 Y 90C, PARA OBTENER EL COMPUESTO DE FORMULA (I). DE APLICACION EN EL TRATAMIENTO DE ULCERAS GASTRICAS Y DUODENALES POR SER UN ANTAGONICO SELECTIVO DE LA HISTAMINA.
ES534363A 1983-07-15 1984-07-16 Procedimiento de preparacion del hidrocloruro de 1-(2-(5-dimetilaminometil-2-(furilmetiltio)-etil)-amino-1-metilamino-2-nitroetileno Expired ES8602732A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU251583A HU193497B (en) 1983-07-15 1983-07-15 Process for preparing sanitidine hydrogen halogenides
HU251483A HU193496B (en) 1983-07-15 1983-07-15 Process for production of basic tioether and it salts i

Publications (2)

Publication Number Publication Date
ES534363A0 ES534363A0 (es) 1985-12-01
ES8602732A1 true ES8602732A1 (es) 1985-12-01

Family

ID=26317525

Family Applications (1)

Application Number Title Priority Date Filing Date
ES534363A Expired ES8602732A1 (es) 1983-07-15 1984-07-16 Procedimiento de preparacion del hidrocloruro de 1-(2-(5-dimetilaminometil-2-(furilmetiltio)-etil)-amino-1-metilamino-2-nitroetileno

Country Status (13)

Country Link
KR (1) KR910007966B1 (es)
AR (1) AR242029A1 (es)
AT (1) AT389873B (es)
CA (1) CA1279328C (es)
CS (1) CS248717B2 (es)
DK (1) DK162525C (es)
ES (1) ES8602732A1 (es)
FI (1) FI88157C (es)
MX (1) MX159694A (es)
NO (1) NO842904L (es)
SE (1) SE457082B (es)
SU (1) SU1384197A3 (es)
YU (1) YU45634B (es)

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
JPS56103171A (en) * 1980-01-08 1981-08-18 Glaxo Group Ltd Manufacture of furan derivative
FI811376L (fi) * 1980-05-13 1981-11-14 Crc Ricerca Chim Foerfarande foer framstaellning av n-/2-///5-(dialkylamino)-metyl-2-furanyl/-metyl/-tio/etyl/-n'-alkyl-2-nitro-1,1-etendiaminer och deras mellanprodukter
ES8200358A1 (es) * 1980-09-30 1981-11-01 Inke Sa Procedimiento para la obtencion de la n-2-5-(dimetilamino)metil-2-furanil metil tio-n-metil-2-nitro-1,1-etenodiamina .
IL63968A (en) * 1980-10-01 1985-10-31 Glaxo Group Ltd Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it
ES8200101A1 (es) * 1980-12-03 1981-10-16 Inke Sa Procedimiento para la obtencion de la n-(2-( ( (5-( (dimeti-lamino)metil)-2-furanil)metil)tio)etil)-n'-metil-2-nitro-1,1-etenodiamina
ES8200674A1 (es) * 1980-12-13 1981-11-16 Parellada Llauger Miguel Procedimiento para la obtencion de la n-(2-((5-((dimetilami-no)metil)furfuril)tio)etil)-n'- metil -2- nitro-1,1- eteno- diamina
DK153481C (da) * 1980-12-30 1989-06-05 Glaxo Group Ltd Fremgangsmaade til fremstilling af ranitidin
DE3170346D1 (en) * 1980-12-30 1985-06-05 Glaxo Group Ltd Process for the preparation of a furan derivative
US4399293A (en) * 1981-02-20 1983-08-16 Glaxo Group Limited Process for the preparation of a furan derivative
ES501844A0 (es) * 1981-05-02 1982-11-01 Especialidades Farmaco Terape Procedimiento para la obtencion de un compuesto derivado delalcohol furfurilico
AR229878A1 (es) * 1981-05-07 1983-12-30 Glaxo Group Ltd Procedimiento para preparar ranitidina
ES502940A0 (es) * 1981-06-10 1982-11-01 Lafarquim Procedimiento para la obtencion de derivados de furil metil mercaptano y sus sales de interes farmacologico
ES507360A0 (es) * 1981-11-20 1982-11-16 Especialidades Latinas Medic U Procedimiento de obtencion de n-(2-5-dimetilamino,metil-2-furanil-metil-tio-etil-n'-metil-s-nitro-etano-diamina.
ES508693A0 (es) * 1982-01-13 1982-11-01 Barisintex Sa "procedimiento para la obtencion de derivados de aminoalkilfuranos".
ES511830A0 (es) * 1982-04-30 1983-02-01 Inke Sa Procedimiento para la obtencion de la n-2-(5-(dimetilanmino)metil-2-furanil)metil)tio)etil)-n'-metil-2-nitro-1,1-eteno- diamina.
ES512315A0 (es) * 1982-05-19 1983-02-01 Tabah Papo Marcelo Procedimiento para la obtencion de un nuevo derivado furanico de interes terapeutico.

Also Published As

Publication number Publication date
SE8403717L (sv) 1985-01-16
KR850001187A (ko) 1985-03-16
MX159694A (es) 1989-08-07
YU122484A (es) 1986-10-31
SE457082B (sv) 1988-11-28
NO842904L (no) 1985-01-16
AR242029A1 (es) 1993-02-26
ES534363A0 (es) 1985-12-01
FI88157B (fi) 1992-12-31
CS248717B2 (en) 1987-02-12
AT389873B (de) 1990-02-12
DK162525C (da) 1992-03-30
ATA227284A (de) 1989-07-15
SE8403717D0 (sv) 1984-07-13
DK345284A (da) 1985-01-16
KR910007966B1 (ko) 1991-10-04
CA1279328C (en) 1991-01-22
SU1384197A3 (ru) 1988-03-23
DK162525B (da) 1991-11-11
FI842822A (fi) 1985-01-16
DK345284D0 (da) 1984-07-13
FI88157C (fi) 1993-04-13
YU45634B (sh) 1992-07-20
FI842822A0 (fi) 1984-07-13

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