CS248717B2 - Production method of the hydrochloride of the 1-(2-(5 dimethylamino-methyl-2-furylmethylthio)ethyl)p)amino-1-methylamino-2-nitroethylene - Google Patents

Production method of the hydrochloride of the 1-(2-(5 dimethylamino-methyl-2-furylmethylthio)ethyl)p)amino-1-methylamino-2-nitroethylene Download PDF

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Publication number
CS248717B2
CS248717B2 CS845492A CS549284A CS248717B2 CS 248717 B2 CS248717 B2 CS 248717B2 CS 845492 A CS845492 A CS 845492A CS 549284 A CS549284 A CS 549284A CS 248717 B2 CS248717 B2 CS 248717B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
hydrochloride
base
optionally
dimethylaminomethyl
Prior art date
Application number
CS845492A
Other languages
Czech (cs)
English (en)
Inventor
Endre Kasstreiner
Oszkar Fuchs
Arpad Lazar
Nandor Makk
Tibor Lang
Lajos Toldy
Bela Stefko
Tibor Balogh
Tibor Somogyi
Jozsef Engler
Judit Kosary
Janos Borvendag
Eszter Diesler
Antal Szabo
Peter Matyus
Beata Vitalis
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU251483A external-priority patent/HU193496B/hu
Priority claimed from HU251583A external-priority patent/HU193497B/hu
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of CS248717B2 publication Critical patent/CS248717B2/cs

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CS845492A 1983-07-15 1984-07-16 Production method of the hydrochloride of the 1-(2-(5 dimethylamino-methyl-2-furylmethylthio)ethyl)p)amino-1-methylamino-2-nitroethylene CS248717B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU251483A HU193496B (en) 1983-07-15 1983-07-15 Process for production of basic tioether and it salts i
HU251583A HU193497B (en) 1983-07-15 1983-07-15 Process for preparing sanitidine hydrogen halogenides

Publications (1)

Publication Number Publication Date
CS248717B2 true CS248717B2 (en) 1987-02-12

Family

ID=26317525

Family Applications (1)

Application Number Title Priority Date Filing Date
CS845492A CS248717B2 (en) 1983-07-15 1984-07-16 Production method of the hydrochloride of the 1-(2-(5 dimethylamino-methyl-2-furylmethylthio)ethyl)p)amino-1-methylamino-2-nitroethylene

Country Status (13)

Country Link
KR (1) KR910007966B1 (sv)
AR (1) AR242029A1 (sv)
AT (1) AT389873B (sv)
CA (1) CA1279328C (sv)
CS (1) CS248717B2 (sv)
DK (1) DK162525C (sv)
ES (1) ES534363A0 (sv)
FI (1) FI88157C (sv)
MX (1) MX159694A (sv)
NO (1) NO842904L (sv)
SE (1) SE457082B (sv)
SU (1) SU1384197A3 (sv)
YU (1) YU45634B (sv)

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
BE886997A (fr) * 1980-01-08 1981-07-08 Glaxo Group Ltd Procede de preparation de la ranitidine et produits intermediaires de cette preparation
FI811376L (fi) * 1980-05-13 1981-11-14 Crc Ricerca Chim Foerfarande foer framstaellning av n-/2-///5-(dialkylamino)-metyl-2-furanyl/-metyl/-tio/etyl/-n'-alkyl-2-nitro-1,1-etendiaminer och deras mellanprodukter
ES495493A0 (es) * 1980-09-30 1981-11-01 Inke Sa Ÿprocedimiento para la obtencion de la n-2-5-(dimetilamino)metil-2-furanil metil tio-n-metil-2-nitro-1,1-etenodiaminaÿ.
IL63968A (en) * 1980-10-01 1985-10-31 Glaxo Group Ltd Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it
ES8200101A1 (es) * 1980-12-03 1981-10-16 Inke Sa Procedimiento para la obtencion de la n-(2-( ( (5-( (dimeti-lamino)metil)-2-furanil)metil)tio)etil)-n'-metil-2-nitro-1,1-etenodiamina
ES497737A0 (es) * 1980-12-13 1981-11-16 Parellada Llauger Miguel Procedimiento para la obtencion de la n-(2-((5-((dimetilami-no)metil)furfuril)tio)etil)-n'- metil -2- nitro-1,1- eteno- diamina
DE3170348D1 (en) * 1980-12-30 1985-06-05 Glaxo Group Ltd Process for the preparation of a furan derivative
ATE13057T1 (de) * 1980-12-30 1985-05-15 Glaxo Group Ltd Verfahren zur herstellung eines furanderivates.
ATE11536T1 (de) * 1981-02-20 1985-02-15 Glaxo Group Limited Verfahren zur herstellung eines furanderivats.
ES8300325A1 (es) * 1981-05-02 1982-11-01 Especialidades Farmaco Terape Procedimiento para la obtencion de un compuesto derivado delalcohol furfurilico
AR229878A1 (es) * 1981-05-07 1983-12-30 Glaxo Group Ltd Procedimiento para preparar ranitidina
ES502940A0 (es) * 1981-06-10 1982-11-01 Lafarquim Procedimiento para la obtencion de derivados de furil metil mercaptano y sus sales de interes farmacologico
ES507360A0 (es) * 1981-11-20 1982-11-16 Especialidades Latinas Medic U Procedimiento de obtencion de n-(2-5-dimetilamino,metil-2-furanil-metil-tio-etil-n'-metil-s-nitro-etano-diamina.
ES508693A0 (es) * 1982-01-13 1982-11-01 Barisintex Sa "procedimiento para la obtencion de derivados de aminoalkilfuranos".
ES511830A0 (es) * 1982-04-30 1983-02-01 Inke Sa Procedimiento para la obtencion de la n-2-(5-(dimetilanmino)metil-2-furanil)metil)tio)etil)-n'-metil-2-nitro-1,1-eteno- diamina.
ES8302686A1 (es) * 1982-05-19 1983-02-01 Tabah Papo Marcelo Procedimiento para la obtencion de un nuevo derivado furanico de interes terapeutico.

Also Published As

Publication number Publication date
DK162525C (da) 1992-03-30
NO842904L (no) 1985-01-16
FI842822A (fi) 1985-01-16
YU122484A (sv) 1986-10-31
FI842822A0 (fi) 1984-07-13
ATA227284A (de) 1989-07-15
AR242029A1 (es) 1993-02-26
DK345284D0 (da) 1984-07-13
ES8602732A1 (es) 1985-12-01
YU45634B (sh) 1992-07-20
SE8403717L (sv) 1985-01-16
KR910007966B1 (ko) 1991-10-04
MX159694A (es) 1989-08-07
DK162525B (da) 1991-11-11
DK345284A (da) 1985-01-16
FI88157B (fi) 1992-12-31
FI88157C (sv) 1993-04-13
SU1384197A3 (ru) 1988-03-23
KR850001187A (ko) 1985-03-16
CA1279328C (en) 1991-01-22
SE457082B (sv) 1988-11-28
AT389873B (de) 1990-02-12
ES534363A0 (es) 1985-12-01
SE8403717D0 (sv) 1984-07-13

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