CA1259609A - 4-¬(bicyclic heterocyclyl)-methyl and -hetero|- piperidines - Google Patents

4-¬(bicyclic heterocyclyl)-methyl and -hetero|- piperidines

Info

Publication number
CA1259609A
CA1259609A CA000471589A CA471589A CA1259609A CA 1259609 A CA1259609 A CA 1259609A CA 000471589 A CA000471589 A CA 000471589A CA 471589 A CA471589 A CA 471589A CA 1259609 A CA1259609 A CA 1259609A
Authority
CA
Canada
Prior art keywords
formula
methyl
radical
parts
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000471589A
Other languages
English (en)
French (fr)
Inventor
Frans E. Janssens
Ludo E.J. Kennis
Joseph L.G. Torremans
Gaston S.M. Diels
Jozef F. Hens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Application granted granted Critical
Publication of CA1259609A publication Critical patent/CA1259609A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CA000471589A 1984-01-09 1985-01-07 4-¬(bicyclic heterocyclyl)-methyl and -hetero|- piperidines Expired CA1259609A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US56936984A 1984-01-09 1984-01-09
US569,369 1984-01-09
US67113584A 1984-11-13 1984-11-13
US671,135 1984-11-13

Publications (1)

Publication Number Publication Date
CA1259609A true CA1259609A (en) 1989-09-19

Family

ID=27075046

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000471589A Expired CA1259609A (en) 1984-01-09 1985-01-07 4-¬(bicyclic heterocyclyl)-methyl and -hetero|- piperidines

Country Status (21)

Country Link
EP (1) EP0151826B1 (en, 2012)
JP (1) JPH0768240B2 (en, 2012)
KR (2) KR870001169B1 (en, 2012)
AU (1) AU573673B2 (en, 2012)
BG (1) BG40965A3 (en, 2012)
CA (1) CA1259609A (en, 2012)
DE (1) DE3486121T2 (en, 2012)
DK (1) DK8985A (en, 2012)
ES (1) ES8706668A1 (en, 2012)
FI (1) FI83867C (en, 2012)
GR (1) GR850060B (en, 2012)
HU (1) HU200338B (en, 2012)
IE (1) IE59707B1 (en, 2012)
IL (1) IL74018A (en, 2012)
MA (1) MA20323A1 (en, 2012)
NO (1) NO160849C (en, 2012)
NZ (1) NZ210776A (en, 2012)
PH (1) PH23995A (en, 2012)
PT (1) PT79809B (en, 2012)
RO (1) RO90622A (en, 2012)
ZW (1) ZW485A1 (en, 2012)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP267A (en) * 1990-07-19 1993-06-16 Janssen Pharmaceutica Nv Novel Oxazolyl derivatives.

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3484096D1 (de) * 1983-11-30 1991-03-14 Janssen Pharmaceutica Nv Bizyklisches heterozyklyl aufveisende n-(bizyklisches heterozyklyl-4-piperidinamine.
US4588722A (en) * 1984-01-09 1986-05-13 Janssen Pharmaceutica N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives
US4804663A (en) * 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
GB8515934D0 (en) * 1985-06-24 1985-07-24 Janssen Pharmaceutica Nv (4-piperidinomethyl and-hetero)purines
FR2587029B1 (fr) * 1985-09-11 1987-10-30 Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
KR950001015B1 (ko) * 1986-01-10 1995-02-07 닛뽕 케미화 가부시끼가이샤 술폭시드 유도체의 제조방법
EP0232937B1 (en) * 1986-02-03 1992-08-19 Janssen Pharmaceutica N.V. Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines
NZ223654A (en) * 1987-03-09 1990-03-27 Janssen Pharmaceutica Nv 1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions
US4943580A (en) * 1987-03-09 1990-07-24 Janssen Pharmaceutica N.V. Anti-histaminic benzimidazole, imidazopyridine and purine derivatives
CA1317939C (en) * 1987-07-01 1993-05-18 Janssen Pharmaceutica Naamloze Vennootschap ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines
GB8716313D0 (en) * 1987-07-10 1987-08-19 Janssen Pharmaceutica Nv 2-(heterocyclylalkyl)imidazopyridines
US4908372A (en) * 1988-10-13 1990-03-13 Merrell Dow Pharmaceuticals Inc. Antihistaminic piperidinyl benzimidazoles
GB8900380D0 (en) * 1989-01-09 1989-03-08 Janssen Pharmaceutica Nv 2-aminopyrimidinone derivatives
PH30434A (en) * 1989-04-07 1997-05-09 Janssen Pharmaceutica Nv Hydroxyalkylfuranyl derivatives
IT1229230B (it) * 1989-05-08 1991-07-26 Dompe Farmaceutici Spa Piperidinilimidazopiridine farmacologicamente attive.
JP2679745B2 (ja) * 1989-06-29 1997-11-19 明治製菓株式会社 アゾール誘導体及びそれらを有効成分とする抗潰瘍剤
US5200407A (en) * 1989-06-29 1993-04-06 Meiji Seika Kaburhiki Kaisha Azole derivatives and anti-ulcerative composition containing same
CA2022451C (en) * 1989-08-03 2001-01-23 Albert Anthony Carr Anti-psychotic piperidynl benzimidazole compounds
GB9000305D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Anticholinergic agents
US5217980A (en) * 1990-07-19 1993-06-08 Janssen Pharmaceutica N.V. Oxazolyl and piperidinyl substituted benimidazolyl compounds
AU8506791A (en) * 1990-10-01 1992-04-28 Janssen Pharmaceutica N.V. Novel 4-piperidinylcarbonyl derivatives
CA2097317C (en) * 1990-12-14 2002-02-12 Albert A. Carr Antiallergic piperdinyl benzimidazoles
TW231291B (en, 2012) * 1992-01-09 1994-10-01 Janssen Pharmaceutica Nv
CA2129995C (en) * 1992-02-13 2000-04-11 Albert A. Carr Piperidinyl thiacyclic derivatives
CA2091204C (en) * 1992-03-11 1997-04-08 Ronald J. Mattson Antiischemic-piperazinyl and piperidinyl-cyclohexanes
ES2048109B1 (es) * 1992-07-20 1994-12-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
US5714498A (en) * 1993-03-18 1998-02-03 Merck, Sharp, & Dohme, Ltd. Benzimidazole derivatives
US5521183A (en) * 1994-08-30 1996-05-28 Allergan Use of 5-HT ligands as anti-pruritic agents
TW429256B (en) * 1995-12-27 2001-04-11 Janssen Pharmaceutica Nv 1-(1,2-disubstituted piperidinyl)-4-(benzimidazolyl- and imidazopyridinyl)-piperidine derivatives
PL343435A1 (en) * 1998-03-06 2001-08-13 Janssen Pharmaceutica Nv Glycine transport inhibitors
ES2228559T3 (es) * 1999-06-28 2005-04-16 Janssen Pharmaceutica N.V. Inhibidores de la replicacion del virus respiratorio sincintial.
BR0011997A (pt) * 1999-06-28 2002-03-05 Janssen Pharmaceutica Nv Inibidores da replicação do vìrus sincicial respiratório
ATE258928T1 (de) 1999-06-28 2004-02-15 Janssen Pharmaceutica Nv Respiratorisches syncytialvirus replikation inhibitoren
TWI225488B (en) * 1999-12-21 2004-12-21 Janssen Pharmaceutica Nv Derivatives of homopiperidinyl substituted benzimidazole analogues
AR033517A1 (es) * 2000-04-08 2003-12-26 Astrazeneca Ab Derivados de piperidina, proceso para su preparacion y uso de estos derivados en la fabricacion de medicamentos
DK2298769T3 (da) * 2001-02-24 2014-01-20 Boehringer Ingelheim Pharma Xanthinderivater, deres fremstilling og deres anvendelse som lægemiddel
US7030150B2 (en) 2001-05-11 2006-04-18 Trimeris, Inc. Benzimidazole compounds and antiviral uses thereof
IL159256A0 (en) 2001-07-02 2004-06-01 Astrazeneca Ab Piperidine derivatives useful as modulators of chemokine receptor activity
US6530660B1 (en) 2001-08-16 2003-03-11 Contour Optik, Inc. Eyeglass frame with a reversible arm
GB0120461D0 (en) 2001-08-22 2001-10-17 Astrazeneca Ab Novel compounds
GB0122503D0 (en) 2001-09-18 2001-11-07 Astrazeneca Ab Chemical compounds
JP2005532991A (ja) * 2002-01-10 2005-11-04 ニューロジェン・コーポレーション メラニン凝集ホルモン受容体リガンド：置換２−（４−ベンジル−ピペラジン−１−イルメチル）−及び２−（４−ベンジル−ジアゼパン−１−イルメチル）−１ｈ−ベンゾイミダゾールアナログ
SE0200843D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0200844D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
US6939877B2 (en) 2002-09-12 2005-09-06 Wyeth Antidepressant piperidine derivatives of heterocycle-fused benzodioxans
CA2513529A1 (en) * 2003-01-17 2004-08-19 Cv Therapeutics Inc. Substituted heterocyclic compounds useful in the treatment of cardiovascular diseases
SE0300957D0 (sv) 2003-04-01 2003-04-01 Astrazeneca Ab Chemical compounds
KR100640783B1 (ko) 2004-10-30 2006-11-01 주식회사 하이닉스반도체 노이즈를 줄일 수 있는 데이터 출력 드라이버
BRPI0608847A2 (pt) 2005-03-08 2010-02-02 Janssen Pharmaceutica Nv derivados de diaza-espiro-[4,4]-nonano substituìdos e seu uso como antagonistas de neurocinina
WO2007011293A1 (en) 2005-07-21 2007-01-25 Astrazeneca Ab Novel piperidine derivatives
JP2011500537A (ja) * 2007-10-11 2011-01-06 グラクソ グループ リミテッド Ｈ１受容体アンタゴニストとしてのフタラジンおよびピリド［３，４−ｄ］ピリダジン化合物
HRP20151380T1 (hr) 2010-09-02 2016-01-15 Suven Life Sciences Limited Spojevi heterociklila kao ligandi receptora histamina h3
US10913736B2 (en) * 2014-08-22 2021-02-09 University Of Washington Specific inhibitors of methionyl-tRNA synthetase
MX384804B (es) 2015-07-02 2025-03-14 Horizon Orphan Llc Analogos de cisteamina resistentes a la ado y sus usos.
WO2017207340A1 (de) * 2016-05-31 2017-12-07 Bayer Pharma Aktiengesellschaft Neue substituierte benzimidazole, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln
GB2585700A (en) 2019-07-12 2021-01-20 Hire Torque Ltd Hydraulic torque wrench and control system for a hydraulic torque wrench

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2857391A (en) * 1955-04-15 1958-10-21 Merck & Co Inc Aminomethylbenzimidazoles
GB1260857A (en) * 1968-07-10 1972-01-19 Hexachimie IMIDAZO-3H-(4,5-b)-PYRIDINE DERIVATIVES
DE2334009A1 (de) * 1973-07-04 1975-01-23 Boehringer Mannheim Gmbh Purin-derivate sowie verfahren zu ihrer herstellung
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
US4219559A (en) * 1979-01-10 1980-08-26 Janssen Pharmaceutica N.V. N-Heterocyclyl-4-piperidinamines
US4335127A (en) * 1979-01-08 1982-06-15 Janssen Pharmaceutica, N.V. Piperidinylalkyl quinazoline compounds, composition and method of use
US4342870A (en) * 1980-03-28 1982-08-03 Janssen Pharmaceutica N.V. Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives
PL129612B1 (en) * 1980-07-24 1984-05-31 Rhone Poulenc Ind Process for preparing novel derivatives of 2,3,6,7-tetrahydrothiazole/3,2-a/pirymidin-5-one
US4443451A (en) * 1981-07-15 1984-04-17 Janssen Pharmaceutica N.V. Bicyclic pyrimidin-5-one derivatives
US4634704A (en) * 1983-10-06 1987-01-06 Janssen Pharmaceutica, N.V. Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines
DE3484096D1 (de) * 1983-11-30 1991-03-14 Janssen Pharmaceutica Nv Bizyklisches heterozyklyl aufveisende n-(bizyklisches heterozyklyl-4-piperidinamine.
US4588722A (en) * 1984-01-09 1986-05-13 Janssen Pharmaceutica N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP267A (en) * 1990-07-19 1993-06-16 Janssen Pharmaceutica Nv Novel Oxazolyl derivatives.

Also Published As

Publication number Publication date
HUT36471A (en) 1985-09-30
FI83867C (fi) 1991-09-10
PH23995A (en) 1990-02-09
ZW485A1 (en) 1986-07-30
FI850079A0 (fi) 1985-01-08
NO850085L (no) 1985-07-10
IE850042L (en) 1985-07-09
IL74018A (en) 1988-08-31
NO160849B (no) 1989-02-27
GR850060B (en, 2012) 1985-04-05
HU200338B (en) 1990-05-28
MA20323A1 (fr) 1985-10-01
AU573673B2 (en) 1988-06-16
EP0151826A1 (en) 1985-08-21
RO90622A (ro) 1986-12-10
DE3486121T2 (de) 1993-07-15
KR850005436A (ko) 1985-08-26
AU3736485A (en) 1985-09-12
EP0151826B1 (en) 1993-03-31
DK8985A (da) 1985-07-10
ES8706668A1 (es) 1987-06-16
KR870001169B1 (ko) 1987-06-15
ES539281A0 (es) 1987-06-16
JPH0768240B2 (ja) 1995-07-26
JPS60185777A (ja) 1985-09-21
DE3486121D1 (en) 1993-05-06
KR900001545B1 (ko) 1990-03-12
NO160849C (no) 1989-06-07
IE59707B1 (en) 1994-03-23
KR880013431A (ko) 1988-11-30
BG40965A3 (en) 1987-03-14
DK8985D0 (da) 1985-01-08
FI850079L (fi) 1985-07-10
NZ210776A (en) 1988-03-30
PT79809A (en) 1985-02-01
PT79809B (en) 1987-01-07
FI83867B (fi) 1991-05-31

Similar Documents

Publication Publication Date Title
CA1259609A (en) 4-¬(bicyclic heterocyclyl)-methyl and -hetero|- piperidines
US4695575A (en) 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
EP0151824B1 (en) N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives
US5258380A (en) (4-piperidinylmethyl and -hetero)purines
US5041448A (en) (4-piperidinylmethyl and -hetero) purines
EP0099139B1 (en) Novel n-(bicyclic heterocyclyl)-4-piperidinamines
EP0282133B1 (en) 1-alkyl substituted benzimidazole derivatives
CA1257258A (en) Bicyclic heterocyclyl containing n-(bicyclic heterocyclyl)-4-piperidinamines
US4835161A (en) Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines
US4988689A (en) ((Pharmacologically active bicyclic heterocyclic)methyl and -heteroatom) substituted hexahydro-1H-azepines and pyrrolidines
EP0297661B1 (en) [(Bicyclic heterocyclyl)methyl and -hetero] substituted hexahydro-1H-azepines and pyrrolidines
KR100206723B1 (ko) 신규 치환된 티아졸릴 및 치환된 피리디닐 유도체
EP0232937A2 (en) Anti-histaminic compositions containing N-heterocyclyl-4-piperidinamines
EP0393738B1 (en) Hydroxyalkylfuranyl derivatives
US4839374A (en) 4-((Bicyclic heterocyclyl)-methyl and -hetero)-piperidines
US5151424A (en) Pharmacologically active (Bicyclic heterocyclyl)methyl and -hetero) substituted hexahydro-1H-azepines and pyrrolidines
US4943580A (en) Anti-histaminic benzimidazole, imidazopyridine and purine derivatives
US5071846A (en) Anti-hystaminic [(bicyclic heterocyclyl) methyl and --hetero] substituted hexahydro-1H-azepines and pyrrolidines
KR880000247B1 (ko) 4-[(두고리 헤테로시클릴)-메틸 및-헤테로] 피페리딘 유도체의 제조방법
CZ16485A3 (cs) Způsob přípravy 4-/(bicyklyl heterocyklyl) methyl a hetero/-piperidinů
PH26643A (en) Bicyclic heterocyclic containing N-(bicyclic hetero-cyclyl)-4-piperidinamines

Legal Events

Date Code Title Description
MKEX Expiry