CA1060448A - Gastric acid secretion agents - Google Patents

Gastric acid secretion agents

Info

Publication number
CA1060448A
CA1060448A CA220,235A CA220235A CA1060448A CA 1060448 A CA1060448 A CA 1060448A CA 220235 A CA220235 A CA 220235A CA 1060448 A CA1060448 A CA 1060448A
Authority
CA
Canada
Prior art keywords
benzimidazole
pyridyl
hydrochloride
methylthio
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA220,235A
Other languages
English (en)
French (fr)
Inventor
Peder B. Berntsson
Stig A. I. Carlsson
Ul F K. Junggren
Lars E. Garberg
Sven E. Sjostrand
Gunhild W. Von Wittken Sundell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hassle AB
Original Assignee
Hassle AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hassle AB filed Critical Hassle AB
Application granted granted Critical
Publication of CA1060448A publication Critical patent/CA1060448A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
CA220,235A 1974-02-18 1975-02-17 Gastric acid secretion agents Expired CA1060448A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7402101A SE418966B (sv) 1974-02-18 1974-02-18 Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan

Publications (1)

Publication Number Publication Date
CA1060448A true CA1060448A (en) 1979-08-14

Family

ID=20320233

Family Applications (1)

Application Number Title Priority Date Filing Date
CA220,235A Expired CA1060448A (en) 1974-02-18 1975-02-17 Gastric acid secretion agents

Country Status (23)

Country Link
JP (1) JPS5924157B2 (nl)
AT (1) AT343659B (nl)
AU (1) AU499639B2 (nl)
BE (1) BE825655A (nl)
CA (1) CA1060448A (nl)
CH (1) CH616160A5 (nl)
CS (1) CS194715B2 (nl)
DD (1) DD119422A5 (nl)
DE (1) DE2504252A1 (nl)
DK (1) DK141122B (nl)
FI (1) FI59590C (nl)
FR (1) FR2261007B1 (nl)
GB (1) GB1500043A (nl)
HK (1) HK67080A (nl)
HU (1) HU172141B (nl)
IE (1) IE40858B1 (nl)
LU (1) LU71872A1 (nl)
MY (1) MY8100208A (nl)
NL (1) NL7501917A (nl)
NO (1) NO142401C (nl)
SE (1) SE418966B (nl)
SU (1) SU795476A3 (nl)
ZA (1) ZA75558B (nl)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
JPS5364103A (en) * 1976-09-24 1978-06-08 Hitachi Ltd Waste heat recovery boiler
IN148930B (nl) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4343805A (en) * 1978-12-16 1982-08-10 John Wyeth & Brother Limited Heterocyclic compounds
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
DE3047388A1 (de) * 1980-12-16 1982-07-15 Basf Ag, 6700 Ludwigshafen Isatogenderivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
ZA825106B (en) * 1981-08-13 1983-04-27 Haessle Ab Novel pharmaceutical compositions
DE3216843C2 (de) * 1982-05-05 1986-10-23 Ludwig Heumann & Co GmbH, 8500 Nürnberg 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US4552886A (en) * 1982-06-07 1985-11-12 Eli Lilly And Company Fungicidal pyridylmethyl-amines
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
US4503139A (en) * 1983-05-09 1985-03-05 Polaroid Corporation Photographic products and processes and novel compounds
US4575554A (en) * 1983-12-05 1986-03-11 The Upjohn Company Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents
US4767770A (en) * 1984-06-18 1988-08-30 Eli Lilly And Company Method of inhibiting aromatase
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
FR2593178B1 (fr) * 1986-01-20 1988-04-29 Esteve Labor Dr Derives de 2-benzimidazolylalkylthio (ou sulfinyle ou sulfonyle) leur preparation et leur application en tant que medicaments.
SE8600658D0 (sv) * 1986-02-14 1986-02-14 Haessle Ab Novel composition of matter
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
SE8604998D0 (sv) 1986-11-21 1986-11-21 Haessle Ab Novel pharmacological compounds
NZ222495A (en) 1986-11-21 1991-04-26 Haessle Ab Benzimidazole derivatives and pharmaceutical compositions
WO1989005643A1 (en) * 1987-12-18 1989-06-29 Pfizer Inc. Heterocyclic-substituted quinoline-carboxylic acids
JPH021280U (nl) * 1988-06-14 1990-01-08
AU617217B2 (en) * 1988-09-20 1991-11-21 Hisamitsu Pharmaceutical Co., Inc. Novel dibenz(b,e)oxepin derivatives
SE8804628D0 (sv) 1988-12-22 1988-12-22 Ab Haessle New compounds
EG19302A (en) * 1988-12-22 1994-11-30 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
JP2679745B2 (ja) * 1989-06-29 1997-11-19 明治製菓株式会社 アゾール誘導体及びそれらを有効成分とする抗潰瘍剤
JPH0347053U (nl) * 1989-09-16 1991-04-30
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
US5049674A (en) * 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
ATE384722T1 (de) * 2002-03-27 2008-02-15 Nycomed Gmbh Alkoxypyridinderivate
US7390819B2 (en) * 2003-02-25 2008-06-24 Altana Pharma Ag Imidazo[4,5-b]quinoline-derivatives and their use as no-synthase inhibitors
JP2007507463A (ja) 2003-10-01 2007-03-29 アルタナ　ファルマ　アクチエンゲゼルシャフト 誘導性ＮＯシンターゼ阻害剤としてのイミダゾ［４，５−ｂ］ピリジン誘導体
EA200600607A1 (ru) 2003-10-01 2006-10-27 Алтана Фарма Аг Производные имидазопиридина в качестве ингибиторов индуцируемой no-синтазы
MXPA06003345A (es) 2003-10-01 2006-06-08 Altana Pharma Ag Derivados de aminopiridina como inhibidores de la no-sintasa inducible.
RS20060195A (en) * 2003-10-01 2008-08-07 Altana Pharma Ag., Imidazopyridine-derivatives as inducible no-synthase inhibitors
ES2309567T3 (es) * 2003-10-01 2008-12-16 Nycomed Gmbh Derivados de imidazopiridinas como inhibidores de no-sintasa inducible.
EP2070923A1 (de) 2007-12-11 2009-06-17 Bayer CropScience AG Insektizide Iminoheterocyclen
US8969349B2 (en) * 2010-05-26 2015-03-03 Sunovion Pharmaceuticals Inc. Substituted quinoxalines and quinoxalinones as PDE-10 inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234058A (nl) * 1968-10-21 1971-06-03

Also Published As

Publication number Publication date
CH616160A5 (en) 1980-03-14
FI750421A (nl) 1975-08-19
MY8100208A (en) 1981-12-31
LU71872A1 (nl) 1975-12-09
BE825655A (fr) 1975-08-18
DE2504252C2 (nl) 1989-02-02
DK141122B (da) 1980-01-21
NO142401C (no) 1980-08-13
FI59590C (fi) 1981-09-10
ZA75558B (en) 1976-01-28
DE2504252A1 (de) 1975-08-21
FR2261007B1 (nl) 1978-11-24
DK141122C (nl) 1980-07-07
HU172141B (hu) 1978-06-28
AU499639B2 (en) 1979-04-26
CS194715B2 (en) 1979-12-31
JPS5924157B2 (ja) 1984-06-07
DD119422A5 (nl) 1976-04-20
IE40858L (en) 1975-08-18
NL7501917A (nl) 1975-08-20
GB1500043A (en) 1978-02-08
SE7402101L (nl) 1975-08-19
IE40858B1 (en) 1979-08-29
AT343659B (de) 1978-06-12
DK54075A (nl) 1975-10-20
NO142401B (no) 1980-05-05
HK67080A (en) 1980-12-05
ATA113775A (de) 1977-10-15
AU7820675A (en) 1976-08-19
SU795476A3 (ru) 1981-01-07
FR2261007A1 (nl) 1975-09-12
JPS50116474A (en) 1975-09-11
SE418966B (sv) 1981-07-06
FI59590B (fi) 1981-05-29
NO750541L (nl) 1975-08-19

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