BRPI0816769A2 - combinações de compostos inibidores de fosfoinositida 3-cinase e agentes quimioterapêuticos, e métodos de uso - Google Patents

combinações de compostos inibidores de fosfoinositida 3-cinase e agentes quimioterapêuticos, e métodos de uso

Info

Publication number
BRPI0816769A2
BRPI0816769A2 BRPI0816769A BRPI0816769A BRPI0816769A2 BR PI0816769 A2 BRPI0816769 A2 BR PI0816769A2 BR PI0816769 A BRPI0816769 A BR PI0816769A BR PI0816769 A BRPI0816769 A BR PI0816769A BR PI0816769 A2 BRPI0816769 A2 BR PI0816769A2
Authority
BR
Brazil
Prior art keywords
phosphoinositide
combinations
methods
kinase inhibitor
chemotherapeutic agents
Prior art date
Application number
BRPI0816769A
Other languages
English (en)
Portuguese (pt)
Inventor
Deepak Sampath
Jeffrey Wallin
Klaus Hoeflich
Leisa Johnson
Lori Friedman
Mallika Singh
Marcia Belvin
Sonal Patel
Ulka Vijapurkar
Original Assignee
Hoffmann La Roche
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39942941&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0816769(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche, Genentech Inc filed Critical Hoffmann La Roche
Publication of BRPI0816769A2 publication Critical patent/BRPI0816769A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0816769A 2007-09-12 2008-09-10 combinações de compostos inibidores de fosfoinositida 3-cinase e agentes quimioterapêuticos, e métodos de uso BRPI0816769A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97177307P 2007-09-12 2007-09-12
PCT/US2008/075883 WO2009036082A2 (en) 2007-09-12 2008-09-10 Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents, and methods of use

Publications (1)

Publication Number Publication Date
BRPI0816769A2 true BRPI0816769A2 (pt) 2016-11-29

Family

ID=39942941

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0816769A BRPI0816769A2 (pt) 2007-09-12 2008-09-10 combinações de compostos inibidores de fosfoinositida 3-cinase e agentes quimioterapêuticos, e métodos de uso

Country Status (18)

Country Link
US (3) US8247397B2 (enExample)
EP (1) EP2205242B1 (enExample)
JP (1) JP5658565B2 (enExample)
KR (1) KR101584823B1 (enExample)
CN (1) CN101939006B (enExample)
AR (1) AR068402A1 (enExample)
AU (1) AU2008298948B2 (enExample)
BR (1) BRPI0816769A2 (enExample)
CA (1) CA2699202C (enExample)
CL (1) CL2008002687A1 (enExample)
ES (1) ES2537352T3 (enExample)
IL (1) IL204333A (enExample)
MX (1) MX338504B (enExample)
PE (2) PE20090678A1 (enExample)
RU (1) RU2523890C2 (enExample)
TW (1) TWI471134B (enExample)
WO (1) WO2009036082A2 (enExample)
ZA (1) ZA201002475B (enExample)

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US20090098135A1 (en) 2009-04-16
AR068402A1 (es) 2009-11-18
CA2699202A1 (en) 2009-03-19
TW200920377A (en) 2009-05-16
MX338504B (es) 2016-04-20
US8604014B2 (en) 2013-12-10
ZA201002475B (en) 2011-06-29
JP2010539177A (ja) 2010-12-16
US8247397B2 (en) 2012-08-21
AU2008298948B2 (en) 2014-09-04
EP2205242B1 (en) 2015-04-15
PE20090678A1 (es) 2009-06-27
CN101939006B (zh) 2015-09-16
MX2010002543A (es) 2010-03-29
CN101939006A (zh) 2011-01-05
KR20100085912A (ko) 2010-07-29
JP5658565B2 (ja) 2015-01-28
PE20140100A1 (es) 2014-02-12
US20130345217A1 (en) 2013-12-26
RU2523890C2 (ru) 2014-07-27
CA2699202C (en) 2016-09-27
EP2205242A2 (en) 2010-07-14
ES2537352T3 (es) 2015-06-05
RU2010112837A (ru) 2011-10-20
KR101584823B1 (ko) 2016-01-22
AU2008298948A1 (en) 2009-03-19
WO2009036082A3 (en) 2009-11-19
TWI471134B (zh) 2015-02-01
US20110223619A1 (en) 2011-09-15
HK1145287A1 (en) 2011-04-15

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