BRPI0811639A2 - Cicloaquilaminas fenil substituídas como inibidores da recaptação de monoamina - Google Patents

Cicloaquilaminas fenil substituídas como inibidores da recaptação de monoamina

Info

Publication number
BRPI0811639A2
BRPI0811639A2 BRPI0811639-3A2A BRPI0811639A BRPI0811639A2 BR PI0811639 A2 BRPI0811639 A2 BR PI0811639A2 BR PI0811639 A BRPI0811639 A BR PI0811639A BR PI0811639 A2 BRPI0811639 A2 BR PI0811639A2
Authority
BR
Brazil
Prior art keywords
cycloakilamines
recaptation
feny
monoamine
inhibitors
Prior art date
Application number
BRPI0811639-3A2A
Other languages
English (en)
Inventor
Liming Shao
Larry Wendel Hardy
Patrick Koch
Rudy Schreiber
Kerry L Spear
Fengjian Wang
Scott Christopher Malcolm
Michael Charles Hewitt
Jianguo Ma
Seth Ribe
Mark A Varney
Una Campbell
Sharon Rae Engel
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc filed Critical Sepracor Inc
Publication of BRPI0811639A2 publication Critical patent/BRPI0811639A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/76—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and etherified hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
BRPI0811639-3A2A 2007-05-31 2008-06-02 Cicloaquilaminas fenil substituídas como inibidores da recaptação de monoamina BRPI0811639A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94124207P 2007-05-31 2007-05-31
PCT/US2008/065571 WO2008151156A1 (en) 2007-05-31 2008-06-02 Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors

Publications (1)

Publication Number Publication Date
BRPI0811639A2 true BRPI0811639A2 (pt) 2014-09-30

Family

ID=40094167

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0811639-3A2A BRPI0811639A2 (pt) 2007-05-31 2008-06-02 Cicloaquilaminas fenil substituídas como inibidores da recaptação de monoamina

Country Status (15)

Country Link
US (3) US8669291B2 (pt)
EP (3) EP3296289A3 (pt)
JP (3) JP5420534B2 (pt)
KR (1) KR101581289B1 (pt)
CN (3) CN101686672A (pt)
AU (1) AU2008259841B2 (pt)
BR (1) BRPI0811639A2 (pt)
CA (1) CA2688493C (pt)
HK (1) HK1200438A1 (pt)
IL (1) IL202405A (pt)
MX (1) MX2009012685A (pt)
NZ (1) NZ580429A (pt)
RU (1) RU2470011C2 (pt)
WO (1) WO2008151156A1 (pt)
ZA (1) ZA200907171B (pt)

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US20100120740A1 (en) * 2008-08-07 2010-05-13 Sepracor Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
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US9126891B2 (en) * 2014-01-29 2015-09-08 MediSynergics, LLC Cycloalkyl-diamines
US9283196B1 (en) * 2013-01-30 2016-03-15 MediSynergics, LLC Cycloalkyl-diamines for CNS disorders
TW201617310A (zh) * 2014-07-18 2016-05-16 拜耳作物科學公司 作為用於抵抗非生物性植物逆境之活性成分的經取代之乙烯基－及炔基－氰基環烷醇與乙烯基－及炔基－氰基雜環烷醇
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KR102397705B1 (ko) 2020-05-29 2022-05-13 재단법인 대구경북첨단의료산업진흥재단 N을 하나 이상 포함하는 5원자의 헤테로아릴 유도체 및 이를 유효성분으로 함유하는 정신질환의 예방 또는 치료용 약학적 조성물
US20240018119A1 (en) 2020-05-29 2024-01-18 Daegu-Gyeongbuk Medical Innovation Foundation Carboxamide derivative and pharmaceutical composition comprising same as active ingredient for preventing or treating mental illness
CN116157124A (zh) 2020-05-29 2023-05-23 大邱庆北尖端医疗产业振兴财团 磺胺衍生物和含其作为活性成分的用于预防或治疗精神疾病的药物组合物

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KR101581289B1 (ko) 2015-12-31
AU2008259841A1 (en) 2008-12-11
NZ580429A (en) 2012-04-27
US20140121282A1 (en) 2014-05-01
US20090005456A1 (en) 2009-01-01
IL202405A0 (en) 2010-06-30
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CA2688493A1 (en) 2008-12-11
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ZA200907171B (en) 2010-12-29
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US8669291B2 (en) 2014-03-11
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CN101686672A (zh) 2010-03-31
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JP2016065085A (ja) 2016-04-28
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