BRPI0810713A8 - Processo e aparelho para a purificação de um poliéster reabsorvível - Google Patents

Processo e aparelho para a purificação de um poliéster reabsorvível

Info

Publication number
BRPI0810713A8
BRPI0810713A8 BRPI0810713A BRPI0810713A BRPI0810713A8 BR PI0810713 A8 BRPI0810713 A8 BR PI0810713A8 BR PI0810713 A BRPI0810713 A BR PI0810713A BR PI0810713 A BRPI0810713 A BR PI0810713A BR PI0810713 A8 BRPI0810713 A8 BR PI0810713A8
Authority
BR
Brazil
Prior art keywords
solvent
polyester
polymer
subsequently
resorbable
Prior art date
Application number
BRPI0810713A
Other languages
English (en)
Inventor
Enderle Anja
Schmitt Manfred
Original Assignee
Boehringer Ingelheim Pharma
Evonik Roehm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma, Evonik Roehm Gmbh filed Critical Boehringer Ingelheim Pharma
Publication of BRPI0810713A2 publication Critical patent/BRPI0810713A2/pt
Publication of BRPI0810713A8 publication Critical patent/BRPI0810713A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/88—Post-polymerisation treatment
    • C08G63/90—Purification; Drying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D25/00—Filters formed by clamping together several filtering elements or parts of such elements
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L63/00—Compositions of epoxy resins; Compositions of derivatives of epoxy resins
    • C08L63/08—Epoxidised polymerised polyenes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08—Lactones or lactides

Abstract

PROCESSO E APARELHO PARA A PURIFICAÇÃO DE UM POLIÉSTER REABSORVÍVEL. A presente invenção refere-se a um processo para purificação de um poliéster reabsorvivel, em que o polímero é dissolvido em um primeiro solvente (12) e, subsequentemente, a solução de polímero é posta em contato íntimo com um segundo solvente (41) sob a ação de altas forças de cisalhamento em um campo de cisalhamento turbulento. Nesse caso, o segundo solvente (41) é um não-solvente para o poliéster reabsorvivel e é miscível, ilimitadamente, com o primeiro solvente (12). Subsequentemente, a suspensão de polimero, que é formada pela adição do segundo solvente (41), é transportada no ou em um corpo de tela cilíndrico, giratório (71) de uma tela de cisalhamento com tambor (70) e, então, a massa de polímero úmida é separada do corpo de tela (71) e, subsequentemente, seca. O processo é adequado para a preparação de poliésteres reabsorviveis de alta qualidade e também pode ser realizado com custo efetivo em uma escala industrial.
BRPI0810713A 2007-05-04 2008-05-02 Processo e aparelho para a purificação de um poliéster reabsorvível BRPI0810713A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007020951A DE102007020951A1 (de) 2007-05-04 2007-05-04 Verfahren und Vorrichtung zur Reinigung eines resorbierbaren Polyesters
PCT/EP2008/055408 WO2008135523A1 (de) 2007-05-04 2008-05-02 Verfahren und vorrichtung zur reinigung eines resorbierbaren polyesters

Publications (2)

Publication Number Publication Date
BRPI0810713A2 BRPI0810713A2 (pt) 2014-10-21
BRPI0810713A8 true BRPI0810713A8 (pt) 2016-06-07

Family

ID=39800573

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0810713A BRPI0810713A8 (pt) 2007-05-04 2008-05-02 Processo e aparelho para a purificação de um poliéster reabsorvível

Country Status (18)

Country Link
US (2) US20100137550A1 (pt)
EP (2) EP2246381A3 (pt)
JP (1) JP5654342B2 (pt)
KR (1) KR20100016203A (pt)
CN (1) CN101675092B (pt)
AR (1) AR066434A1 (pt)
AU (1) AU2008248649A1 (pt)
BR (1) BRPI0810713A8 (pt)
CA (1) CA2686045A1 (pt)
DE (1) DE102007020951A1 (pt)
ES (1) ES2627727T3 (pt)
HK (1) HK1138027A1 (pt)
IL (1) IL201279A (pt)
MX (1) MX2009011077A (pt)
NZ (1) NZ580827A (pt)
RU (1) RU2473577C2 (pt)
TW (1) TWI428365B (pt)
WO (1) WO2008135523A1 (pt)

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JP5567581B2 (ja) 2008-11-07 2014-08-06 サムヤン バイオファーマシューティカルズ コーポレイション 高純度ポリ乳酸、その塩またはその誘導体、及びその精製方法
DE102011014131A1 (de) 2011-03-15 2012-09-20 Thyssenkrupp Uhde Gmbh Verfahren zur Trocknung von feuchtem Polymerpulver und dafür geeignete Vorrichtung
US8735504B2 (en) 2012-05-02 2014-05-27 Warsaw Orthopedic, Inc. Methods for preparing polymers having low residual monomer content
CN103421172B (zh) * 2012-05-23 2016-01-20 上海现代药物制剂工程研究中心有限公司 一种生物可降解聚酯的纯化工艺
WO2014108191A1 (en) 2013-01-10 2014-07-17 Evonik Industries Ag Electronic device unit comprising a polymer coating
CN103105047B (zh) * 2013-01-30 2014-10-22 青岛沃隆花生机械有限公司 连续式去水机
US10011681B2 (en) 2013-04-11 2018-07-03 Mitsui Chemicals, Inc. Process for producing a lactic acid-glycolic acid copolymer or a salt thereof
JP6312176B2 (ja) * 2013-08-29 2018-04-18 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツングＥｖｏｎｉｋ Ｒｏｅｈｍ ＧｍｂＨ 粉末の形の生体吸収性ポリエステルの製造方法
MX2017001281A (es) 2014-09-07 2017-10-31 Ossio Ltd Material anisotropico biocompuesto, implantes medicos que lo comprenden y metodos para el tratamiento del mismo.
EP3218422B1 (en) 2014-11-14 2018-11-07 Evonik Röhm GmbH Process for preparing a bio-resorbable polyester in particulate form
KR102581716B1 (ko) 2014-12-26 2023-09-21 오씨오 리미티드 연속-섬유 강화된 생체복합재 의료용 임플란트
CA2987209A1 (en) 2015-06-10 2016-12-15 Evonik Rohm Gmbh Process for preparing a powder comprising a human coagulation factor protein and a lactic acid polymer
IL263882B1 (en) * 2016-06-27 2024-04-01 Ossio Ltd Bio-composite medical implants reinforced with fibers and with a high mineral content
KR20200052330A (ko) 2017-09-07 2020-05-14 오씨오 리미티드 섬유 강화 생체복합재 나사산 형성 임플란트
JP2019167402A (ja) * 2018-03-22 2019-10-03 三井化学株式会社 乳酸−グリコール酸共重合体を含む粉体の製造方法
CN112469397B (zh) 2018-05-08 2022-12-02 赢创运营有限公司 包含可生物再吸收的聚酯、亲水性聚合物和酰化的人乳铁蛋白衍生肽的纳米颗粒
DE102019205941A1 (de) * 2019-04-25 2020-10-29 Robert Bosch Gmbh Verfahren zur Behandlung mindestens einer Oberfläche eines Polymers
CN114058072A (zh) * 2020-08-07 2022-02-18 Apk股份公司 通过集成的滚筒干燥和挤出从聚合物溶液除去溶剂的方法
CN112595033B (zh) * 2020-12-10 2022-11-08 万华化学集团股份有限公司 一种颜色稳定的聚碳酸酯粉末的制备方法
CN112694605B (zh) * 2020-12-29 2023-03-17 浙江圣兆药物科技股份有限公司 一种聚酯类产品的纯化方法和生产设备
TW202304473A (zh) 2021-04-01 2023-02-01 美商百健Ｍａ公司 向中樞神經系統之核酸遞送

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Also Published As

Publication number Publication date
AR066434A1 (es) 2009-08-19
EP2147036B1 (de) 2017-03-22
CA2686045A1 (en) 2008-11-13
NZ580827A (en) 2012-11-30
EP2147036A1 (de) 2010-01-27
RU2009144850A (ru) 2011-06-10
AU2008248649A1 (en) 2008-11-13
US20110144301A1 (en) 2011-06-16
WO2008135523A1 (de) 2008-11-13
MX2009011077A (es) 2009-11-02
TWI428365B (zh) 2014-03-01
ES2627727T3 (es) 2017-07-31
US9156942B2 (en) 2015-10-13
KR20100016203A (ko) 2010-02-12
IL201279A0 (en) 2010-05-31
JP2010526200A (ja) 2010-07-29
JP5654342B2 (ja) 2015-01-14
TW200909474A (en) 2009-03-01
IL201279A (en) 2013-11-28
CN101675092B (zh) 2012-01-11
BRPI0810713A2 (pt) 2014-10-21
US20100137550A1 (en) 2010-06-03
RU2473577C2 (ru) 2013-01-27
EP2246381A3 (de) 2017-10-25
CN101675092A (zh) 2010-03-17
DE102007020951A1 (de) 2008-11-06
HK1138027A1 (en) 2010-08-13
EP2246381A2 (de) 2010-11-03
US20110288267A2 (en) 2011-11-24

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: EVONIK ROEHM GMBH (DE)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B350 Update of information on the portal [chapter 15.35 patent gazette]