BRPI0810647A2 - " uso de trans carotenóides bipolares como um pré-tratamento e no tratamento de doença vascular periférica ". - Google Patents

" uso de trans carotenóides bipolares como um pré-tratamento e no tratamento de doença vascular periférica ".

Info

Publication number
BRPI0810647A2
BRPI0810647A2 BRPI0810647-9A2A BRPI0810647A BRPI0810647A2 BR PI0810647 A2 BRPI0810647 A2 BR PI0810647A2 BR PI0810647 A BRPI0810647 A BR PI0810647A BR PI0810647 A2 BRPI0810647 A2 BR PI0810647A2
Authority
BR
Brazil
Prior art keywords
pretreatment
treatment
vascular disease
peripheral vascular
bipolar trans
Prior art date
Application number
BRPI0810647-9A2A
Other languages
English (en)
Inventor
John L Gainer
Original Assignee
Diffusion Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diffusion Pharmaceuticals Llc filed Critical Diffusion Pharmaceuticals Llc
Publication of BRPI0810647A2 publication Critical patent/BRPI0810647A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
BRPI0810647-9A2A 2007-04-13 2008-04-11 " uso de trans carotenóides bipolares como um pré-tratamento e no tratamento de doença vascular periférica ". BRPI0810647A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90771807P 2007-04-13 2007-04-13
PCT/US2008/004708 WO2008136900A1 (en) 2007-04-13 2008-04-11 Use of bipolar trans carotenoids as a pretreatment and in the treatment of peripheral vascular disease

Publications (1)

Publication Number Publication Date
BRPI0810647A2 true BRPI0810647A2 (pt) 2014-11-04

Family

ID=39854321

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0810647-9A2A BRPI0810647A2 (pt) 2007-04-13 2008-04-11 " uso de trans carotenóides bipolares como um pré-tratamento e no tratamento de doença vascular periférica ".

Country Status (13)

Country Link
US (2) US8293804B2 (pt)
EP (3) EP3483140A1 (pt)
JP (2) JP2010524855A (pt)
KR (1) KR101570131B1 (pt)
CN (1) CN101687757A (pt)
AU (1) AU2008246305B2 (pt)
BR (1) BRPI0810647A2 (pt)
CA (1) CA2683760C (pt)
EA (1) EA200970944A1 (pt)
IL (1) IL201438A (pt)
MX (1) MX2009010988A (pt)
WO (1) WO2008136900A1 (pt)
ZA (1) ZA200907757B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005518453A (ja) * 2002-02-25 2005-06-23 ディフュージョン・ファーマシューティカルズ・エルエルシー 二極性トランスカロテノイド塩およびそれらの使用
US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
EP2540696B1 (en) * 2005-02-24 2020-01-01 Diffusion Pharmaceuticals LLC Trans carotenoids, formulation and uses
EP3483140A1 (en) 2007-04-13 2019-05-15 Diffusion Pharmaceuticals LLC Use of bipolar trans carotenoids as a pretreatment and in the treatment of peripheral vascular disease
CA2703946A1 (en) * 2007-10-31 2009-05-07 Diffusion Pharmaceuticals Llc A new class of therapeutics that enhance small molecule diffusion
KR101875843B1 (ko) * 2009-06-22 2018-07-06 디퓨젼 파마슈티컬즈 엘엘씨 확산 촉진 화합물 및 그 화합물 단독 또는 혈전 용해제와 합쳐진 화합물의 용도
AU2011262361A1 (en) * 2010-06-02 2013-01-10 Diffusion Pharmaceuticals Llc Oral formulations of bipolar trans carotenoids
GB201120772D0 (en) * 2011-12-02 2012-01-11 Ip Science Ltd Cocoa-based food products
US11185523B2 (en) 2016-03-24 2021-11-30 Diffusion Pharmaceuticals Llc Use of bipolar trans carotenoids with chemotherapy and radiotherapy for treatment of cancer
CN108403677B (zh) * 2018-05-03 2020-06-05 北京市心肺血管疾病研究所 藏红花素在预防和治疗胸主动脉夹层/主动脉瘤中的应用
CA3107753A1 (en) * 2018-07-30 2020-02-06 Diffusion Pharmaceuticals Llc Diffusion enhancing compounds and their use with thrombectomy and embolectomy and other vascular disease procedures
WO2023081779A1 (en) * 2021-11-03 2023-05-11 Diffusion Pharmaceuticals Llc Crystalline forms of a diffusion enhancing compound

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Also Published As

Publication number Publication date
KR20100016396A (ko) 2010-02-12
IL201438A0 (en) 2010-05-31
AU2008246305B2 (en) 2013-03-21
CN101687757A (zh) 2010-03-31
EP2589588A1 (en) 2013-05-08
WO2008136900A1 (en) 2008-11-13
EP2146948A4 (en) 2010-08-04
IL201438A (en) 2015-03-31
JP2014139221A (ja) 2014-07-31
US8293804B2 (en) 2012-10-23
EP3483140A1 (en) 2019-05-15
CA2683760A1 (en) 2008-11-13
AU2008246305A1 (en) 2008-11-13
EP2146948A1 (en) 2010-01-27
JP2010524855A (ja) 2010-07-22
US8901174B2 (en) 2014-12-02
ZA200907757B (en) 2012-04-25
US20080255246A1 (en) 2008-10-16
MX2009010988A (es) 2010-03-15
KR101570131B1 (ko) 2015-11-18
CA2683760C (en) 2015-05-19
US20120035256A1 (en) 2012-02-09
EA200970944A1 (ru) 2010-06-30

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