BRPI0718155A2 - Composto, uso de um composto, método para tratar doenças mediadas por glk, e, processo para a preparação de um composto. - Google Patents

Composto, uso de um composto, método para tratar doenças mediadas por glk, e, processo para a preparação de um composto.

Info

Publication number
BRPI0718155A2
BRPI0718155A2 BRPI0718155-8A2A BRPI0718155A BRPI0718155A2 BR PI0718155 A2 BRPI0718155 A2 BR PI0718155A2 BR PI0718155 A BRPI0718155 A BR PI0718155A BR PI0718155 A2 BRPI0718155 A2 BR PI0718155A2
Authority
BR
Brazil
Prior art keywords
compound
preparing
mediated diseases
treating glk
glk
Prior art date
Application number
BRPI0718155-8A2A
Other languages
English (en)
Portuguese (pt)
Inventor
Nathaniel George Martin
Darren Mckerrecher
Kurt Gordon Pike
Michael James Waring
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38925536&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0718155(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BRPI0718155A2 publication Critical patent/BRPI0718155A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BRPI0718155-8A2A 2006-10-26 2007-10-25 Composto, uso de um composto, método para tratar doenças mediadas por glk, e, processo para a preparação de um composto. BRPI0718155A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86305606P 2006-10-26 2006-10-26
US95737007P 2007-08-22 2007-08-22
PCT/GB2007/004057 WO2008050117A1 (en) 2006-10-26 2007-10-25 Benzoyl amino heterocyclyl compounds as glucokinase (glk) activators

Publications (1)

Publication Number Publication Date
BRPI0718155A2 true BRPI0718155A2 (pt) 2013-11-19

Family

ID=38925536

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0718155-8A2A BRPI0718155A2 (pt) 2006-10-26 2007-10-25 Composto, uso de um composto, método para tratar doenças mediadas por glk, e, processo para a preparação de um composto.

Country Status (20)

Country Link
US (2) US7671060B2 (enExample)
EP (2) EP2078000A1 (enExample)
JP (2) JP4673429B2 (enExample)
KR (1) KR20090084880A (enExample)
CN (1) CN101805299A (enExample)
AR (1) AR063393A1 (enExample)
AU (1) AU2007310624B2 (enExample)
BR (1) BRPI0718155A2 (enExample)
CA (1) CA2667316A1 (enExample)
CL (1) CL2007003061A1 (enExample)
CO (1) CO6160314A2 (enExample)
IL (1) IL198143A0 (enExample)
MX (1) MX2009004467A (enExample)
NO (1) NO20091596L (enExample)
PE (1) PE20080927A1 (enExample)
RU (1) RU2440992C2 (enExample)
SA (1) SA07280576B1 (enExample)
TW (1) TW200825060A (enExample)
UY (1) UY30659A1 (enExample)
WO (1) WO2008050117A1 (enExample)

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TW200600086A (en) * 2004-06-05 2006-01-01 Astrazeneca Ab Chemical compound
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EP2573087A1 (en) 2007-09-21 2013-03-27 Array Biopharma, Inc. Pyridin-2-yl-amino-1,2,4-thiadiazole derivatives as glucokinase activators for the treatment of diabetes mellitus
EP2324028A2 (en) 2008-08-04 2011-05-25 AstraZeneca AB Therapeutic agents 414
GB0902434D0 (en) * 2009-02-13 2009-04-01 Astrazeneca Ab Chemical process
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WO2010116177A1 (en) 2009-04-09 2010-10-14 Astrazeneca Ab A pyrazolo [4,5-e] pyrimidine derivative and its use to treat diabetes and obesity
AR076221A1 (es) * 2009-04-09 2011-05-26 Astrazeneca Ab Derivado de pirazol [4,5-e] pirimidina y su uso para tratar diabetes y obesidad
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EP2582709B1 (de) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
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RU2440992C2 (ru) 2012-01-27
US7671060B2 (en) 2010-03-02
MX2009004467A (es) 2009-07-27
EP2272834A1 (en) 2011-01-12
CL2007003061A1 (es) 2008-08-01
AU2007310624A1 (en) 2008-05-02
RU2009114802A (ru) 2010-12-10
SA07280576B1 (ar) 2011-06-22
US7964725B2 (en) 2011-06-21
AU2007310624A8 (en) 2009-05-14
TW200825060A (en) 2008-06-16
KR20090084880A (ko) 2009-08-05
PE20080927A1 (es) 2008-09-20
JP2010507641A (ja) 2010-03-11
CA2667316A1 (en) 2008-05-02
JP4673429B2 (ja) 2011-04-20
UY30659A1 (es) 2008-05-31
WO2008050117A1 (en) 2008-05-02
IL198143A0 (en) 2009-12-24
EP2078000A1 (en) 2009-07-15
AU2007310624B2 (en) 2011-09-01
NO20091596L (no) 2009-06-30
US20100173825A1 (en) 2010-07-08
CO6160314A2 (es) 2010-05-20
JP2011046724A (ja) 2011-03-10
US20080318968A1 (en) 2008-12-25
AR063393A1 (es) 2009-01-28

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