BRPI0512281A - análise dimensional de conjugados de sacarìdeo com gpc & sec-mals - Google Patents

análise dimensional de conjugados de sacarìdeo com gpc & sec-mals

Info

Publication number
BRPI0512281A
BRPI0512281A BRPI0512281-3A BRPI0512281A BRPI0512281A BR PI0512281 A BRPI0512281 A BR PI0512281A BR PI0512281 A BRPI0512281 A BR PI0512281A BR PI0512281 A BRPI0512281 A BR PI0512281A
Authority
BR
Brazil
Prior art keywords
mals
gpc
sec
sample
dimensional analysis
Prior art date
Application number
BRPI0512281-3A
Other languages
English (en)
Portuguese (pt)
Inventor
Giorgio Capannoli
Valeria Carinci
Sandro D Ascenzi
Claudia Magagnoli
Original Assignee
Chiron Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Srl filed Critical Chiron Srl
Publication of BRPI0512281A publication Critical patent/BRPI0512281A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55544—Bacterial toxins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Spectrometry And Color Measurement (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
BRPI0512281-3A 2004-06-21 2005-06-21 análise dimensional de conjugados de sacarìdeo com gpc & sec-mals BRPI0512281A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0413868.1A GB0413868D0 (en) 2004-06-21 2004-06-21 Dimensional anlaysis of saccharide conjugates
PCT/IB2005/002532 WO2006000920A2 (en) 2004-06-21 2005-06-21 Dimensional analysis of saccharide conjugates with gpc & sec-mals

Publications (1)

Publication Number Publication Date
BRPI0512281A true BRPI0512281A (pt) 2008-02-26

Family

ID=32750313

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0512281-3A BRPI0512281A (pt) 2004-06-21 2005-06-21 análise dimensional de conjugados de sacarìdeo com gpc & sec-mals

Country Status (13)

Country Link
US (2) US8163296B2 (cg-RX-API-DMAC10.html)
EP (2) EP2374473B1 (cg-RX-API-DMAC10.html)
JP (5) JP2008503716A (cg-RX-API-DMAC10.html)
CN (1) CN1976725B (cg-RX-API-DMAC10.html)
AU (1) AU2005256961B2 (cg-RX-API-DMAC10.html)
BR (1) BRPI0512281A (cg-RX-API-DMAC10.html)
CA (1) CA2571565C (cg-RX-API-DMAC10.html)
ES (2) ES2443465T3 (cg-RX-API-DMAC10.html)
GB (1) GB0413868D0 (cg-RX-API-DMAC10.html)
MX (2) MXPA06015188A (cg-RX-API-DMAC10.html)
NZ (1) NZ552449A (cg-RX-API-DMAC10.html)
RU (1) RU2422156C2 (cg-RX-API-DMAC10.html)
WO (1) WO2006000920A2 (cg-RX-API-DMAC10.html)

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GB0413868D0 (en) * 2004-06-21 2004-07-21 Chiron Srl Dimensional anlaysis of saccharide conjugates
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US8195405B2 (en) * 2009-06-30 2012-06-05 Wyatt Technology Corporation Method for characterizing reversible association of macromolecules at high concentration
PT2493498T (pt) 2009-10-30 2017-05-24 Glaxosmithkline Biologicals Sa Purificação de sacáridos capsulares de staphylococcus aureus tipo 5 e tipo 8
EP4023330A1 (en) * 2009-12-15 2022-07-06 Waters Technologies Corporation Device and methods for performing size exclusion chromatography
CN107029223A (zh) * 2010-05-26 2017-08-11 西莱克塔生物科技公司 合成纳米载体联合疫苗
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US10481164B2 (en) 2012-03-26 2019-11-19 Amgen Inc. Method for using light scattering in real time to directly monitor and control impurity removal in purification processes
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CN109890413B (zh) 2016-09-02 2024-04-16 赛诺菲巴斯德股份有限公司 脑膜炎奈瑟氏菌疫苗
IL267709B2 (en) 2016-12-30 2025-04-01 Vaxcyte Inc Polypeptide-antigen conjugates with unnatural amino acids
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SG11201906519RA (en) 2017-01-31 2019-08-27 Pfizer Neisseria meningitidis compositions and methods thereof
CN109459523B (zh) 2017-09-06 2022-11-08 上海绿谷制药有限公司 一种测定酸性糖可溶性盐重均分子量和含量的方法
CN109459504B (zh) * 2017-09-06 2022-05-27 绿谷(上海)医药科技有限公司 一种测定聚古罗糖醛酸硫酸酯盐重均分子量和含量的方法
CA3155669A1 (en) 2019-09-27 2021-04-01 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
JP7409055B2 (ja) * 2019-12-05 2024-01-09 株式会社島津製作所 検出器の出力を補正する方法、および多角度光散乱検出器

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Also Published As

Publication number Publication date
US8163296B2 (en) 2012-04-24
RU2422156C2 (ru) 2011-06-27
CN1976725A (zh) 2007-06-06
JP6218327B2 (ja) 2017-10-25
JP6661568B2 (ja) 2020-03-11
JP2011246490A (ja) 2011-12-08
JP2015180707A (ja) 2015-10-15
EP2374473A1 (en) 2011-10-12
RU2007102016A (ru) 2008-07-27
MXPA06015188A (es) 2007-03-27
AU2005256961B2 (en) 2011-06-23
JP2014111654A (ja) 2014-06-19
WO2006000920A3 (en) 2006-03-30
JP2017134084A (ja) 2017-08-03
EP1778291B1 (en) 2013-10-30
WO2006000920A2 (en) 2006-01-05
ES2688796T3 (es) 2018-11-07
US20120207781A1 (en) 2012-08-16
US20080248059A1 (en) 2008-10-09
CN1976725B (zh) 2012-08-29
MX344621B (es) 2017-01-03
GB0413868D0 (en) 2004-07-21
CA2571565C (en) 2014-08-12
JP2008503716A (ja) 2008-02-07
EP2374473B1 (en) 2018-07-18
EP1778291A2 (en) 2007-05-02
CA2571565A1 (en) 2006-01-05
ES2443465T3 (es) 2014-02-19
NZ552449A (en) 2010-05-28
AU2005256961A1 (en) 2006-01-05

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 39/095 (2006.01), A61K 47/64 (2017.01), A61K

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B25D Requested change of name of applicant approved

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS SRL (IT)

B25D Requested change of name of applicant approved

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS SRL (IT)

B25L Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS SRL (IT)

Free format text: ANULADA A PUBLICACAO CODIGO 25.4 NA RPI NO 2547 DE 29/10/2019 POR NAO TER SIDO DISPONIBILIZADO O PARECER.

B25A Requested transfer of rights approved

Owner name: NOVARTIS PHARMA AG (CH)

B25A Requested transfer of rights approved

Owner name: NOVARTIS AG (CH)

B25A Requested transfer of rights approved

Owner name: GLAXOSMITHKLINE BIOLOGICALS S.A. (BE)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]