BRPI0212028B1 - sistema terapêutico transdérmico (tts) e seu processo de produção - Google Patents

sistema terapêutico transdérmico (tts) e seu processo de produção

Info

Publication number
BRPI0212028B1
BRPI0212028B1 BRPI0212028A BRPI0212028A BRPI0212028B1 BR PI0212028 B1 BRPI0212028 B1 BR PI0212028B1 BR PI0212028 A BRPI0212028 A BR PI0212028A BR PI0212028 A BRPI0212028 A BR PI0212028A BR PI0212028 B1 BRPI0212028 B1 BR PI0212028B1
Authority
BR
Brazil
Prior art keywords
active substance
transdermal therapeutic
tts
therapeutic system
fentanyl
Prior art date
Application number
BRPI0212028A
Other languages
English (en)
Inventor
Mueller Walter
Original Assignee
Lts Lohmann Therapie Systeme Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lts Lohmann Therapie Systeme Ag filed Critical Lts Lohmann Therapie Systeme Ag
Publication of BR0212028A publication Critical patent/BR0212028A/pt
Publication of BRPI0212028B1 publication Critical patent/BRPI0212028B1/pt
Publication of BRPI0212028B8 publication Critical patent/BRPI0212028B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

sistema terapêutico transdérmico (tts) com a substância ativa fentanila. a presente invenção refere-se a sistemas terapêuticos transdérmicos com fentanila ou com um derivado análogo à fentanila como substância ativa. para excluir superdosagens inadvertidas pela liberação descontrolada da substância ativa como conseqüência de um dano, a substância ativa está contida em microrreservatórios enchidos com líquido da camada contendo substância ativa. eventualmente, a camada contendo substância ativa pode ser provida de uma membrana.
BRPI0212028 2001-08-24 2002-07-10 sistema terapêutico transdérmico (tts) e seu processo de produção BRPI0212028B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10141651A DE10141651B4 (de) 2001-08-24 2001-08-24 Transdermales Therapeutisches System (TTS) mit dem Wirkstoff Fentanyl und Verfahren zu seiner Herstellung
PCT/EP2002/007663 WO2003018071A1 (de) 2001-08-24 2002-07-10 Transdermales therapeutisches system (tts) mit dem wirkstoff fentanyl

Publications (3)

Publication Number Publication Date
BR0212028A BR0212028A (pt) 2004-08-03
BRPI0212028B1 true BRPI0212028B1 (pt) 2020-11-24
BRPI0212028B8 BRPI0212028B8 (pt) 2021-05-25

Family

ID=7696569

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0212028 BRPI0212028B8 (pt) 2001-08-24 2002-07-10 sistema terapêutico transdérmico (tts) e seu processo de produção

Country Status (24)

Country Link
US (2) US7390500B2 (pt)
EP (1) EP1418951B1 (pt)
JP (1) JP4628673B2 (pt)
KR (1) KR100895188B1 (pt)
CN (1) CN100438859C (pt)
AT (1) ATE455541T1 (pt)
AU (1) AU2002321199B2 (pt)
BR (1) BRPI0212028B8 (pt)
CA (1) CA2457245C (pt)
CY (1) CY1109954T1 (pt)
DE (2) DE10141651B4 (pt)
DK (1) DK1418951T3 (pt)
ES (1) ES2339640T3 (pt)
HK (1) HK1069534A1 (pt)
HU (1) HU229942B1 (pt)
IL (2) IL160515A0 (pt)
MX (1) MXPA04001679A (pt)
NZ (1) NZ530795A (pt)
PL (1) PL204348B1 (pt)
PT (1) PT1418951E (pt)
RU (1) RU2311908C2 (pt)
TW (1) TW570815B (pt)
WO (1) WO2003018071A1 (pt)
ZA (1) ZA200400473B (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
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DE10141650C1 (de) * 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
US20040086551A1 (en) 2002-10-30 2004-05-06 Miller Kenneth J. Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl
JP2006517124A (ja) * 2003-02-07 2006-07-20 エルテーエス ローマン テラピー−ジステーメ アーゲー 活性物質の浸透を促進するために熱を用いるのに適した経皮治療システム及びその使用
PT1613297E (pt) * 2003-04-14 2007-08-23 Lohmann Therapie Syst Lts Emplastro terapêutico com matriz de polissiloxano compreendendo capsaicina
US20110086086A1 (en) * 2005-07-26 2011-04-14 Pfizer Inc Transdermal system for varenicline
DE102006019293A1 (de) * 2006-04-21 2007-10-25 LABTEC Gesellschaft für technologische Forschung und Entwicklung mbH Pflaster, enthaltend ein Fentanyl Analogum
GB0615429D0 (en) * 2006-08-03 2006-09-13 Chowdhury Dewan F H Transdermal drug delivery with temporal control
DE102006054732B4 (de) * 2006-11-21 2010-12-30 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit Ionenpaar-Mikroreservoiren
DE102006054731B4 (de) 2006-11-21 2013-02-28 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie
DE102008016804B4 (de) * 2008-04-02 2012-01-05 Lts Lohmann Therapie-Systeme Ag Selbstzerstörendes transdermales therapeutisches System mit verbesserter Funktionalität und Wirksamkeit sowie seine Verwendung
US20100221313A1 (en) * 2008-12-01 2010-09-02 Innovative Pharmaceuticals, Llc Transdermal reservoir patch
MX2012000947A (es) * 2009-07-21 2012-02-29 Mylan Inc Proceso para la manufactura continua de un parche transdermico basado en polisobutileno.
US9822088B2 (en) 2011-03-30 2017-11-21 The United States Of America As Represented By The Administrator Of Nasa Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor
DE102011080390B3 (de) * 2011-08-03 2012-07-12 Acino Ag Applikationshilfe
TW201338813A (zh) 2011-12-12 2013-10-01 Lohmann Therapie Syst Lts 經皮遞送系統
TW201431570A (zh) * 2012-11-22 2014-08-16 Ucb Pharma Gmbh 用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片
BR112015029920A2 (pt) * 2013-06-04 2017-07-25 Lts Lohmann Therapie Systeme Ag sistema de administração transdérmica
BR112015032929B1 (pt) 2013-07-03 2022-08-23 Lts Lohmann Therapie-Systeme Ag Sistema terapêutico transdérmico com componente eletrônico e métodos de produção de um sistema terapêutico transdérmico
CN106456568B (zh) 2014-05-20 2020-03-27 Lts勒曼治疗系统股份公司 包含界面调节剂的经皮递送系统
JP6895755B2 (ja) 2014-05-20 2021-06-30 エルテーエス ローマン テラピー−ジステーメ アーゲー 経皮送達システムにおける活性薬剤の放出を調節するための方法
JP6573913B2 (ja) 2014-05-20 2019-09-11 エルテーエス ローマン テラピー−ジステーメ アーゲー ロチゴチンを含む経皮送達システム
US9962340B2 (en) 2015-06-09 2018-05-08 Life Tech Global, Llc Device and method for the transdermal delivery of cannabidiol
US10272125B2 (en) * 2015-09-14 2019-04-30 Life Tech Global, Llc Transdermal delivery of cannabidiol with other active moieties including cannabinoids
US9650338B1 (en) 2016-07-29 2017-05-16 VDM Biochemicals, Inc. Opioid antagonist compounds and methods of making and using
DE102017107468B4 (de) 2017-04-06 2019-02-21 Lts Lohmann Therapie-Systeme Ag Verfahren zur herstellung eines, insbesondere oralen, wirkstofflaminats und wirkstofflaminat, insbesondere orales wirkstofflaminat
US10300454B2 (en) 2017-04-18 2019-05-28 Breakthrough Technologies, Llc. Sulfur production
WO2019043172A1 (en) * 2017-09-04 2019-03-07 Lts Lohmann Therapie-Systeme Ag TRANSDERMAL DELIVERY SYSTEM COMPRISING AN EMULSIFIER
JP6912122B2 (ja) * 2019-02-28 2021-07-28 日本臓器製薬株式会社 経皮投与製剤

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US4906463A (en) * 1986-12-22 1990-03-06 Cygnus Research Corporation Transdermal drug-delivery composition
US4822802A (en) * 1987-02-24 1989-04-18 Alza Corporation Method of fentanly administration for postoperative pain relief
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JP4346696B2 (ja) * 1996-05-28 2009-10-21 久光製薬株式会社 経皮治療用装置
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Also Published As

Publication number Publication date
MXPA04001679A (es) 2004-05-31
RU2004108849A (ru) 2005-05-10
WO2003018071A1 (de) 2003-03-06
CY1109954T1 (el) 2012-05-23
IL160515A0 (en) 2004-07-25
RU2311908C2 (ru) 2007-12-10
NZ530795A (en) 2005-08-26
PT1418951E (pt) 2010-04-07
ES2339640T3 (es) 2010-05-24
DE50214184D1 (de) 2010-03-11
CA2457245C (en) 2010-09-07
DE10141651B4 (de) 2007-02-15
PL366857A1 (en) 2005-02-07
CN100438859C (zh) 2008-12-03
EP1418951A1 (de) 2004-05-19
CN1545407A (zh) 2004-11-10
BRPI0212028B8 (pt) 2021-05-25
DK1418951T3 (da) 2010-05-10
HU229942B1 (en) 2015-01-28
HK1069534A1 (pt) 2005-05-27
BR0212028A (pt) 2004-08-03
PL204348B1 (pl) 2010-01-29
US20040234583A1 (en) 2004-11-25
IL160515A (en) 2009-09-22
TW570815B (en) 2004-01-11
JP2005501865A (ja) 2005-01-20
DE10141651A1 (de) 2003-03-13
US7390500B2 (en) 2008-06-24
JP4628673B2 (ja) 2011-02-09
KR20040029021A (ko) 2004-04-03
ATE455541T1 (de) 2010-02-15
AU2002321199B2 (en) 2007-08-16
EP1418951B1 (de) 2010-01-20
CA2457245A1 (en) 2003-03-06
KR100895188B1 (ko) 2009-04-24
HUP0401512A3 (en) 2012-08-28
ZA200400473B (en) 2004-10-14
HUP0401512A2 (hu) 2004-12-28
US20080274167A1 (en) 2008-11-06

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

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Ipc: A61K 31/4468 (2011.01), A61K 9/70 (2011.01), A61P

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 24/11/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

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B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

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B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

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