BR9908496A - Vacinas vivas recombinadas e adjuvadas - Google Patents

Vacinas vivas recombinadas e adjuvadas

Info

Publication number
BR9908496A
BR9908496A BR9908496-1A BR9908496A BR9908496A BR 9908496 A BR9908496 A BR 9908496A BR 9908496 A BR9908496 A BR 9908496A BR 9908496 A BR9908496 A BR 9908496A
Authority
BR
Brazil
Prior art keywords
acrylic
maleic anhydride
copolymer
polymers
live recombinant
Prior art date
Application number
BR9908496-1A
Other languages
English (en)
Inventor
Jean-Christophe Franc Audonnet
Jules Maarten Minke
Original Assignee
Merial Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Sas filed Critical Merial Sas
Publication of BR9908496A publication Critical patent/BR9908496A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção: <B>"VACINAS VIVAS RECOMBINADAS E ADJUVADAS"<D>. A vacina viva recombinante compreende um vetor viral que incorpora e que expressa in vivo uma seq³ência nucleotídica heteróloga, de preferência um gene de um agente patogênico, e pelo menos um composto adjuvante escolhido dentre os polímeros acrílico ou metacrílico e os copolímeros de anidrido maléico e de derivado de alcenila. Trata-se notadamente de um polímero do ácido acrílico ou metacrílico reticulado por um éter polialcenílico de açúcar ou de poliálcool (carbómero), em particular por um alilsacarose ou pelo alilpentaeritritol. Pode-se também tratar-se de um copolímero de anidrido maléico e de etileno reticulado, por exemplo por diviniléter.
BR9908496-1A 1998-03-03 1999-03-01 Vacinas vivas recombinadas e adjuvadas BR9908496A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9802800A FR2775601B1 (fr) 1998-03-03 1998-03-03 Vaccins vivants recombines et adjuves
PCT/FR1999/000453 WO1999044633A1 (fr) 1998-03-03 1999-03-01 Vaccins vivants recombines et adjuves

Publications (1)

Publication Number Publication Date
BR9908496A true BR9908496A (pt) 2000-12-05

Family

ID=9523775

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9908496-1A BR9908496A (pt) 1998-03-03 1999-03-01 Vacinas vivas recombinadas e adjuvadas

Country Status (22)

Country Link
US (2) US6713068B1 (pt)
EP (1) EP1058558B1 (pt)
JP (1) JP2002505300A (pt)
KR (1) KR20010041507A (pt)
CN (2) CN1263511C (pt)
AR (1) AR018135A1 (pt)
AT (1) ATE287728T1 (pt)
AU (1) AU762479B2 (pt)
BR (1) BR9908496A (pt)
CA (1) CA2321903C (pt)
DE (1) DE69923434T2 (pt)
DK (1) DK1058558T3 (pt)
ES (1) ES2237931T3 (pt)
FR (1) FR2775601B1 (pt)
HU (1) HU228431B1 (pt)
IL (1) IL137872A0 (pt)
NZ (1) NZ506370A (pt)
PL (1) PL197405B1 (pt)
PT (1) PT1058558E (pt)
TW (1) TW592700B (pt)
WO (1) WO1999044633A1 (pt)
ZA (1) ZA991662B (pt)

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Also Published As

Publication number Publication date
CN1263511C (zh) 2006-07-12
AU762479B2 (en) 2003-06-26
PT1058558E (pt) 2005-06-30
CN1846786A (zh) 2006-10-18
US6713068B1 (en) 2004-03-30
CN1291899A (zh) 2001-04-18
HUP0101207A2 (hu) 2001-08-28
TW592700B (en) 2004-06-21
ATE287728T1 (de) 2005-02-15
PL342820A1 (en) 2001-07-02
US7507416B2 (en) 2009-03-24
HUP0101207A3 (en) 2003-10-28
CA2321903C (en) 2011-05-31
HU228431B1 (en) 2013-03-28
EP1058558B1 (fr) 2005-01-26
AR018135A1 (es) 2001-10-31
WO1999044633A1 (fr) 1999-09-10
DK1058558T3 (da) 2005-06-06
ZA991662B (en) 2000-10-12
NZ506370A (en) 2003-07-25
FR2775601A1 (fr) 1999-09-10
EP1058558A1 (fr) 2000-12-13
ES2237931T3 (es) 2005-08-01
DE69923434T2 (de) 2006-01-05
CA2321903A1 (en) 1999-09-10
DE69923434D1 (de) 2005-03-03
PL197405B1 (pl) 2008-03-31
FR2775601B1 (fr) 2001-09-21
KR20010041507A (ko) 2001-05-25
JP2002505300A (ja) 2002-02-19
AU3257199A (en) 1999-09-20
US20060057163A1 (en) 2006-03-16
IL137872A0 (en) 2001-10-31

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