ATE442858T1 - Nukleinsäureadjuvantien - Google Patents

Nukleinsäureadjuvantien

Info

Publication number
ATE442858T1
ATE442858T1 AT01274277T AT01274277T ATE442858T1 AT E442858 T1 ATE442858 T1 AT E442858T1 AT 01274277 T AT01274277 T AT 01274277T AT 01274277 T AT01274277 T AT 01274277T AT E442858 T1 ATE442858 T1 AT E442858T1
Authority
AT
Austria
Prior art keywords
nucleic acid
molecules
truncated
acid adjuvants
coding region
Prior art date
Application number
AT01274277T
Other languages
English (en)
Inventor
Joel Haynes
Joshua Arrington
Original Assignee
Powderject Vaccines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Powderject Vaccines Inc filed Critical Powderject Vaccines Inc
Application granted granted Critical
Publication of ATE442858T1 publication Critical patent/ATE442858T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55544Bacterial toxins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT01274277T 2000-11-27 2001-11-26 Nukleinsäureadjuvantien ATE442858T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72431500A 2000-11-27 2000-11-27
PCT/US2001/043151 WO2003004055A2 (en) 2000-11-27 2001-11-26 Nucleic acid adjuvants

Publications (1)

Publication Number Publication Date
ATE442858T1 true ATE442858T1 (de) 2009-10-15

Family

ID=24909936

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01274277T ATE442858T1 (de) 2000-11-27 2001-11-26 Nukleinsäureadjuvantien

Country Status (16)

Country Link
EP (1) EP1379273B1 (de)
JP (1) JP4221289B2 (de)
KR (1) KR20040045391A (de)
CN (1) CN1317034C (de)
AT (1) ATE442858T1 (de)
AU (1) AU2001297988B2 (de)
BR (1) BR0115646A (de)
CA (1) CA2429708A1 (de)
DE (1) DE60139959D1 (de)
DK (1) DK1379273T3 (de)
ES (1) ES2332261T3 (de)
IL (2) IL156041A0 (de)
MX (1) MXPA03004638A (de)
NZ (1) NZ526175A (de)
PT (1) PT1379273E (de)
WO (1) WO2003004055A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ546554A (en) 2003-10-10 2009-04-30 Powderject Vaccines Inc Nucleic acid constructs
ES2387850T3 (es) 2004-02-11 2012-10-02 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.R.L. Proteína de fusión al antígeno carcinoembrionario y sus usos
GB0507997D0 (en) * 2005-02-01 2005-05-25 Powderject Vaccines Inc Nucleic acid constructs
JP5311508B2 (ja) * 2008-05-07 2013-10-09 国立大学法人大阪大学 非共有結合型コラーゲン架橋剤
WO2012036746A1 (en) 2010-09-15 2012-03-22 Randall J Mrsny Systems and methods of delivery of bioactive agents using bacterial toxin-derived transport sequences
US11246915B2 (en) 2010-09-15 2022-02-15 Applied Molecular Transport Inc. Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo
CN103060253A (zh) * 2013-01-24 2013-04-24 麻丽丹 霍乱弧菌ctxAB基因的质粒克隆菌株以及制备方法和应用
RU2723178C2 (ru) 2014-05-07 2020-06-09 ЭППЛАЙД МОЛЕКЬЮЛАР ТРАНСПОРТ ЭлЭлСи Слитые молекулы, происходящие от Cholix-токсина, для пероральной доставки биологически активных нагрузок
KR20210076881A (ko) 2018-03-08 2021-06-24 어플라이드 몰레큘라 트랜스포트 인크. 경구 전달용 독소-유래 전달 구조체
PL3650037T3 (pl) 2018-11-07 2022-06-06 Applied Molecular Transport Inc. Konstrukty dostarczające do transcytozy i powiązane z nimi sposoby
TW202120521A (zh) 2019-08-16 2021-06-01 美商應用分子運輸公司 組合物、配方及介白素生產及純化

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5219740A (en) 1987-02-13 1993-06-15 Fred Hutchinson Cancer Research Center Retroviral gene transfer into diploid fibroblasts for gene therapy
TW404844B (en) 1993-04-08 2000-09-11 Oxford Biosciences Ltd Needleless syringe
GB9416663D0 (en) 1994-08-17 1994-10-12 Oxford Bioscience Limited Particle delivery
JP3853360B2 (ja) 1994-10-24 2006-12-06 パウダージェクト リサーチ リミテッド 粒子供給装置
GB9426379D0 (en) 1994-12-23 1995-03-01 Oxford Biosciences Ltd Particle delivery
US6056960A (en) * 1995-06-07 2000-05-02 Kaslow; Harvey R. Compositions exhibiting ADP-ribosyltransferase activity and methods for the preparation and use thereof
GB9612629D0 (en) 1996-06-17 1996-08-21 Oxford Biosciences Ltd Method for providing dense particle compositions for use in transdermal particle delivery
US5980898A (en) * 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization

Also Published As

Publication number Publication date
EP1379273B1 (de) 2009-09-16
JP2004536107A (ja) 2004-12-02
DE60139959D1 (de) 2009-10-29
ES2332261T3 (es) 2010-02-01
AU2001297988B2 (en) 2006-10-26
WO2003004055A2 (en) 2003-01-16
CN1317034C (zh) 2007-05-23
EP1379273A2 (de) 2004-01-14
DK1379273T3 (da) 2009-11-09
IL156041A (en) 2010-05-17
CA2429708A1 (en) 2003-01-16
IL156041A0 (en) 2003-12-23
BR0115646A (pt) 2005-12-13
WO2003004055A3 (en) 2003-11-20
MXPA03004638A (es) 2004-04-20
NZ526175A (en) 2006-01-27
JP4221289B2 (ja) 2009-02-12
KR20040045391A (ko) 2004-06-01
PT1379273E (pt) 2009-11-27
CN1537013A (zh) 2004-10-13

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