HUP0101207A2 - Rekombináns és adjuvánstartalmú élő oltóanyagok - Google Patents

Rekombináns és adjuvánstartalmú élő oltóanyagok

Info

Publication number
HUP0101207A2
HUP0101207A2 HU0101207A HUP0101207A HUP0101207A2 HU P0101207 A2 HUP0101207 A2 HU P0101207A2 HU 0101207 A HU0101207 A HU 0101207A HU P0101207 A HUP0101207 A HU P0101207A HU P0101207 A2 HUP0101207 A2 HU P0101207A2
Authority
HU
Hungary
Prior art keywords
adjuvant compound
adjuvant
vivo
copolymer
nucleotide sequence
Prior art date
Application number
HU0101207A
Other languages
English (en)
Inventor
Jean-Christophe Francis Audonnet
Jules Maarten Minke
Original Assignee
Merial
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial filed Critical Merial
Publication of HUP0101207A2 publication Critical patent/HUP0101207A2/hu
Publication of HUP0101207A3 publication Critical patent/HUP0101207A3/hu
Publication of HU228431B1 publication Critical patent/HU228431B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány tárgya rekombináns élő oltóanyag, amely egy heterológnukleotidszekvenciát, előnyösen egy patogén ágens egy génjéttartalmazó és in vivo expresszáló vírusvektort, és legalább egyadjuvánsvegyületet tartalmaz, amely adjuvánsvegyület akrilsav- vagymetakrilsav-polimer vagy maleinanhidrid és alkenilszármazék kopolimer.Az adjuvánsvegyület előnyösen akrilsav- vagy metakrilsav-polimer,amely egy cukor vagy egy polialkohol polialkenil-éterével (karbomer),előnyösen egy allil-szacharózzal vagy egy allil-pentaeritritollalkeresztkötött. Lehet továbbá maleinanhidrid és etilén például divinil-éterrel keresztkötött kopolimere is. A találmány tárgya továbbá azadjuvánsvegyület alkalmazása oltóanyag előállítására, továbbáoltóanyagkészlet, amely fagyasztva szárított, heterológnukleotidszekvenciát és in vivo expresszáló rekombináns élőoltóanyagot, másrészről adjuvánsvegyületet oldatát tartalmazza. Ó
HU0101207A 1998-03-03 1999-03-01 Live recombined vaccines with adjuvant HU228431B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9802800A FR2775601B1 (fr) 1998-03-03 1998-03-03 Vaccins vivants recombines et adjuves
PCT/FR1999/000453 WO1999044633A1 (fr) 1998-03-03 1999-03-01 Vaccins vivants recombines et adjuves

Publications (3)

Publication Number Publication Date
HUP0101207A2 true HUP0101207A2 (hu) 2001-08-28
HUP0101207A3 HUP0101207A3 (en) 2003-10-28
HU228431B1 HU228431B1 (en) 2013-03-28

Family

ID=9523775

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0101207A HU228431B1 (en) 1998-03-03 1999-03-01 Live recombined vaccines with adjuvant

Country Status (22)

Country Link
US (2) US6713068B1 (hu)
EP (1) EP1058558B1 (hu)
JP (1) JP2002505300A (hu)
KR (1) KR20010041507A (hu)
CN (2) CN1263511C (hu)
AR (1) AR018135A1 (hu)
AT (1) ATE287728T1 (hu)
AU (1) AU762479B2 (hu)
BR (1) BR9908496A (hu)
CA (1) CA2321903C (hu)
DE (1) DE69923434T2 (hu)
DK (1) DK1058558T3 (hu)
ES (1) ES2237931T3 (hu)
FR (1) FR2775601B1 (hu)
HU (1) HU228431B1 (hu)
IL (1) IL137872A0 (hu)
NZ (1) NZ506370A (hu)
PL (1) PL197405B1 (hu)
PT (1) PT1058558E (hu)
TW (1) TW592700B (hu)
WO (1) WO1999044633A1 (hu)
ZA (1) ZA991662B (hu)

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Also Published As

Publication number Publication date
CN1263511C (zh) 2006-07-12
AU762479B2 (en) 2003-06-26
PT1058558E (pt) 2005-06-30
CN1846786A (zh) 2006-10-18
US6713068B1 (en) 2004-03-30
CN1291899A (zh) 2001-04-18
BR9908496A (pt) 2000-12-05
TW592700B (en) 2004-06-21
ATE287728T1 (de) 2005-02-15
PL342820A1 (en) 2001-07-02
US7507416B2 (en) 2009-03-24
HUP0101207A3 (en) 2003-10-28
CA2321903C (en) 2011-05-31
HU228431B1 (en) 2013-03-28
EP1058558B1 (fr) 2005-01-26
AR018135A1 (es) 2001-10-31
WO1999044633A1 (fr) 1999-09-10
DK1058558T3 (da) 2005-06-06
ZA991662B (en) 2000-10-12
NZ506370A (en) 2003-07-25
FR2775601A1 (fr) 1999-09-10
EP1058558A1 (fr) 2000-12-13
ES2237931T3 (es) 2005-08-01
DE69923434T2 (de) 2006-01-05
CA2321903A1 (en) 1999-09-10
DE69923434D1 (de) 2005-03-03
PL197405B1 (pl) 2008-03-31
FR2775601B1 (fr) 2001-09-21
KR20010041507A (ko) 2001-05-25
JP2002505300A (ja) 2002-02-19
AU3257199A (en) 1999-09-20
US20060057163A1 (en) 2006-03-16
IL137872A0 (en) 2001-10-31

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