BR9703475A - Dna recombinante autonomamente replicável em células de bactérias corineformes bactéria corineforme e processo para a produção de l-lisina - Google Patents

Dna recombinante autonomamente replicável em células de bactérias corineformes bactéria corineforme e processo para a produção de l-lisina

Info

Publication number
BR9703475A
BR9703475A BR9703475A BR9703475A BR9703475A BR 9703475 A BR9703475 A BR 9703475A BR 9703475 A BR9703475 A BR 9703475A BR 9703475 A BR9703475 A BR 9703475A BR 9703475 A BR9703475 A BR 9703475A
Authority
BR
Brazil
Prior art keywords
corineform bacteria
lysine
cells
production
recombinant dna
Prior art date
Application number
BR9703475A
Other languages
English (en)
Other versions
BR9703475B1 (pt
Inventor
Tsuyoshi Nakamatsu
Yasuhiko Yoshihara
Seiko Hirano
Atsushi Hayakawa
Masakazu Sugimoto
Masako Izui
Eiichi Nakano
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15324210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9703475(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of BR9703475A publication Critical patent/BR9703475A/pt
Publication of BR9703475B1 publication Critical patent/BR9703475B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
BRPI9703475-4A 1996-06-05 1997-06-05 vetor recombinante autonomamente replicável em células de bactérias corineformes, bactéria corineforme geneticamente engenheirada, e, processo para a produção de l-lisina. BR9703475B1 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14281296A JP4035855B2 (ja) 1996-06-05 1996-06-05 Ｌ−リジンの製造法

Publications (2)

Publication Number Publication Date
BR9703475A true BR9703475A (pt) 1998-09-29
BR9703475B1 BR9703475B1 (pt) 2012-02-22

Family

ID=15324210

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9703475-4A BR9703475B1 (pt) 1996-06-05 1997-06-05 vetor recombinante autonomamente replicável em células de bactérias corineformes, bactéria corineforme geneticamente engenheirada, e, processo para a produção de l-lisina.

Country Status (11)

Country Link
US (1) US6090597A (pt)
EP (1) EP0811682B2 (pt)
JP (1) JP4035855B2 (pt)
CN (2) CN1171442A (pt)
BR (1) BR9703475B1 (pt)
DE (1) DE69727260T3 (pt)
DK (1) DK0811682T4 (pt)
ES (1) ES2214567T5 (pt)
HU (1) HU223764B1 (pt)
PL (1) PL186081B1 (pt)
SK (1) SK284739B6 (pt)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9606379A (pt) * 1995-06-07 1997-08-12 Ajinomoto Kk Dna recombinante replicavel em células de bactérias corinformes bactérias corineformes processo para produzir l-lisina
IL120923A0 (en) * 1997-05-27 1997-09-30 Amylum Nv A combined process for the production of lysine and its salts and of a further weak acid and a salt thereof
CA2307019A1 (en) * 1997-10-17 1999-04-29 The Regents Of The University Of Minnesota Production of lysine using salt tolerant, methanol utilizing bacillus
JP2003135066A (ja) * 1999-03-19 2003-05-13 Ajinomoto Co Inc Ｌ−リジンの製造法
CN1298854C (zh) 1999-07-02 2007-02-07 味之素株式会社 编码蔗糖pts酶ⅱ的dna
EP1241246B1 (en) * 1999-12-24 2008-12-10 Ajinomoto Co., Inc. Process for producing l-amino acid
US6927046B1 (en) * 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
US6833329B1 (en) * 2000-06-22 2004-12-21 Micron Technology, Inc. Methods of forming oxide regions over semiconductor substrates
US6660657B1 (en) * 2000-08-07 2003-12-09 Micron Technology, Inc. Methods of incorporating nitrogen into silicon-oxide-containing layers
EP1368367B1 (en) 2001-02-08 2017-05-03 Archer-Daniels-Midland Company Polynucleotide constructs for increased lysine production
JP2009095237A (ja) * 2006-02-02 2009-05-07 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
DE102006032634A1 (de) 2006-07-13 2008-01-17 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
EP1881076A1 (en) * 2006-07-17 2008-01-23 Evonik Degussa GmbH Method for producing L-amino acids
PL2262894T3 (pl) 2008-03-03 2015-02-27 Global Bio Chem Tech Group Company Limited Rekombinowany mikroorganizm i sposób wytwarzania l-lizyny
DE102008001874A1 (de) 2008-05-20 2009-11-26 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
EP2302066A4 (en) 2008-07-09 2012-02-08 Ajinomoto Kk METHOD FOR PRODUCING AMINOHYDROXYBENZOIC ACID
EP2772546B1 (en) 2011-10-25 2019-05-15 Ajinomoto Co., Inc. Secretion production method for protein
CN103946371B (zh) 2011-11-02 2016-07-06 味之素株式会社 用于分泌产生蛋白质的方法
IN2014CN04002A (pt) 2011-11-02 2015-10-23 Ajinomoto Kk
EP2860259B1 (en) 2013-02-18 2016-11-09 Ajinomoto Co., Inc. Method for producing protein by precipitation
RU2013119826A (ru) 2013-04-29 2014-11-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Коринеформная бактерия и способ получения гетерологичных гибридных белков
CN104946731B (zh) * 2014-03-28 2019-12-20 中国中医科学院中药研究所 快速检测金银花的pcr试剂盒及检测方法
DE102014208199A1 (de) 2014-04-30 2015-11-05 Evonik Degussa Gmbh Verfahren zur Produktion von L-Aminosäuren unter Verwendung eines alkaliphilen Bakteriums
PL2940143T3 (pl) 2014-04-30 2020-06-29 Evonik Operations Gmbh Sposób wytwarzania L-aminokwasów z użyciem bakterii bazofilowych
EP2940039A1 (de) 2014-04-30 2015-11-04 Evonik Degussa GmbH Verfahren zur Produktion von L-Aminosäuren in Corynebakterien unter Verwendung eines Glycin spaltenden Systems
EP3375883B1 (en) 2015-11-12 2021-02-03 Ajinomoto Co., Inc. Method for producing n epsilon -acyl-l-lysine
RU2729012C2 (ru) 2015-11-27 2020-08-03 Эвоник Оперейшенс ГмбХ Способ получения l-метионина
EP3453758A4 (en) 2016-05-02 2019-12-04 Ajinomoto Co., Inc. FC PROTEIN WITH AZID GROUP
CN109937258B (zh) 2016-10-21 2023-06-23 味之素株式会社 蛋白质的分泌产生方法
EP3530748B1 (en) 2016-10-21 2021-06-02 Ajinomoto Co., Inc. Method for the secretory production proteins
BR112019018859A2 (pt) 2017-03-28 2020-04-14 Ajinomoto Kk método para produzir rna objetivo
EP3456833A1 (en) * 2017-09-18 2019-03-20 Evonik Degussa GmbH Method for the fermentative production of l-amino acids
EP3467099A1 (en) 2017-10-05 2019-04-10 Evonik Degussa GmbH Method for the fermentative production of l-amino acids
WO2019078095A1 (en) 2017-10-16 2019-04-25 Ajinomoto Co., Inc. PROCESS FOR PRODUCTION OF PROTEIN HAVING ALPHA-HYDROXYLANTIC PEPTIDYLGLYCIN MONOOXYGENASE ACTIVITY
JP7226449B2 (ja) 2017-12-26 2023-02-21 味の素株式会社 発酵によるグリシンの製造方法
EP3756466A4 (en) 2018-02-20 2021-11-24 Ajinomoto Co., Inc. RNA SILENCING INDUCTION PROCESS
KR20210002575A (ko) 2018-04-20 2021-01-08 아지노모토 가부시키가이샤 단백질의 분비 생산법
RU2019128538A (ru) 2018-09-26 2021-03-11 Эвоник Оперейшенс ГмбХ Способ ферментативного получения l-лизина
WO2020071538A1 (en) 2018-10-05 2020-04-09 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
WO2020085511A1 (ja) 2018-10-25 2020-04-30 味の素株式会社 タンパク質の分泌生産法
JPWO2020090979A1 (ja) 2018-10-31 2021-09-24 味の素株式会社 抗体に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩
BR112021019284A2 (pt) 2019-03-29 2022-02-01 Ajinomoto Kk Métodos para produzir alolactose e para produzir um indutor de expressão gênica
EP3967676A4 (en) 2019-05-08 2023-02-08 Ajinomoto Co., Inc. PROCESS FOR PRODUCTION OF VANILLIN
EP4053287A4 (en) 2019-10-28 2023-11-01 Ajinomoto Co., Inc. METHOD FOR PRODUCING BENZALDEHYDE
JPWO2021112249A1 (pt) 2019-12-06 2021-06-10
EP4115740A4 (en) 2020-03-04 2024-04-03 Ajinomoto Co., Inc. MUTANT TRANSGLUTAMINASE
BR112023005635A2 (pt) 2020-09-29 2023-04-25 Ajinomoto Kk Método e composição para produzir um alimento, transglutaminase mutante, gene, vetor, e, microrganismo
CA3211636A1 (en) * 2021-03-09 2022-09-15 Daesang Corporation Corynebacterium glutamicum variant having improved l-lysine production ability, and method for producing l-lysine by using same
CN112921012B (zh) * 2021-03-18 2022-10-11 江南大学 谷氨酸棒杆菌meso-2,6-二氨基庚二酸脱氢酶突变体及其应用
JPWO2023282315A1 (pt) 2021-07-07 2023-01-12
WO2023222510A1 (en) 2022-05-18 2023-11-23 Evonik Operations Gmbh Biotechnological production of desferrioxamines and analogs thereof
WO2023222505A1 (en) 2022-05-18 2023-11-23 Evonik Operations Gmbh Biotechnological production of monomers of bisucaberins, desferrioxamines and analogs thereof
WO2023222515A1 (en) 2022-05-18 2023-11-23 Evonik Operations Gmbh Biotechnological production of bisucaberins, desferrioxamines and analogs thereof

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861722A (en) * 1983-08-24 1989-08-29 Ajinomoto Company, Inc. Coryneform bacteria carrying recombinant plasmids and their use in the fermentative production of L-lysine
JPH0746994B2 (ja) * 1984-10-04 1995-05-24 味の素株式会社 発酵法によるｌ−アミノ酸の製造法
JPH0611230B2 (ja) * 1985-06-14 1994-02-16 協和醗酵工業株式会社 新規組換え体プラスミド
JPH07112431B2 (ja) † 1985-09-06 1995-12-06 味の素株式会社 遺伝子発現調節法
JP2708168B2 (ja) † 1988-02-23 1998-02-04 昭和電工株式会社 微生物の改良
JP2817172B2 (ja) * 1989-03-07 1998-10-27 味の素株式会社 発酵法によるｌ―リジンの製法
US5426052A (en) * 1989-04-10 1995-06-20 Regents Of The University Of Minnesota Bacillus MGA3 diaminopimelate decarboxylase gene
JP2967996B2 (ja) * 1989-06-06 1999-10-25 協和醗酵工業株式会社 Ｌ―トリプトファンの製造法
DE3943117A1 (de) * 1989-12-27 1991-07-04 Forschungszentrum Juelich Gmbh Verfahren zur fermentativen herstellung von aminosaeure, insbesondere l-lysin, dafuer geeignete mikroorganismen und rekombinante dna
EP0469517A3 (en) * 1990-07-30 1992-10-28 Kyowa Hakko Kogyo Co., Ltd. Process for producing l-glutamic acid
FR2665711B1 (fr) † 1990-08-08 1993-08-13 Centre Nat Rech Scient Integron de corynebacterie, procede de transformation d'une corynebacterie par ledit integron et corynebacterie obtenue.
IL99272A0 (en) † 1990-08-23 1992-07-15 Exogene Corp Expression vectors for expression of native and heterologous genes in coryneform and a method for expressing bacterial hemoglobin in coryneform
JPH07108228B2 (ja) † 1990-10-15 1995-11-22 味の素株式会社 温度感受性プラスミド
US5693781A (en) † 1991-06-03 1997-12-02 Mitsubishi Chemical Corporation Promoter DNA fragment from coryneform bacteria
EP0584375B1 (en) † 1992-03-11 2001-12-05 Ajinomoto Co., Inc. Transposable element originating in bacterium of the genus brevibacterium
DE4208785A1 (de) † 1992-03-19 1993-09-23 Degussa Verfahren zum auffinden von insertionselementen (is-elemente) oder transposonen
JPH05284970A (ja) * 1992-04-07 1993-11-02 Mitsubishi Petrochem Co Ltd ジアミノピメリン酸デヒドロゲナーゼをコードする遺伝子ｄｎａ及びその利用
JP3473042B2 (ja) 1992-04-28 2003-12-02 味の素株式会社 変異型アスパルトキナーゼ遺伝子
JPH0775579A (ja) * 1993-09-08 1995-03-20 Mitsubishi Chem Corp ジアミノピメリン酸デカルボキシラーゼをコードする遺伝子を含むｄｎａ断片およびその利用
JPH07140614A (ja) † 1993-11-12 1995-06-02 Fuji Photo Film Co Ltd ハロゲン化銀カラー感光材料
JPH07155184A (ja) * 1993-12-08 1995-06-20 Ajinomoto Co Inc 発酵法によるｌ−リジンの製造法
BR9606379A (pt) † 1995-06-07 1997-08-12 Ajinomoto Kk Dna recombinante replicavel em células de bactérias corinformes bactérias corineformes processo para produzir l-lisina
KR100671785B1 (ko) 1999-04-19 2007-01-19 교와 핫꼬 고교 가부시끼가이샤 신규한 탈감작형 아스파르토키나아제
DE10359660A1 (de) † 2003-12-18 2005-07-28 Basf Ag Psod-Expressionseinheiten

Also Published As

Publication number Publication date
HU9700851D0 (en) 1997-06-30
JP4035855B2 (ja) 2008-01-23
BR9703475B1 (pt) 2012-02-22
CN1908174B (zh) 2010-05-26
EP0811682B2 (en) 2017-04-19
CN1171442A (zh) 1998-01-28
DE69727260T3 (de) 2017-08-24
SK59397A3 (en) 1997-12-10
PL320324A1 (en) 1997-12-08
JPH09322774A (ja) 1997-12-16
EP0811682A2 (en) 1997-12-10
HUP9700851A3 (en) 2000-08-28
ES2214567T5 (es) 2017-08-24
DK0811682T4 (en) 2017-06-12
PL186081B1 (pl) 2003-10-31
HUP9700851A2 (hu) 1999-06-28
SK284739B6 (sk) 2005-10-06
DE69727260T2 (de) 2004-10-14
HU223764B1 (hu) 2005-01-28
DK0811682T3 (da) 2004-05-17
EP0811682B1 (en) 2004-01-21
CN1908174A (zh) 2007-02-07
ES2214567T3 (es) 2004-09-16
EP0811682A3 (en) 1998-06-10
DE69727260D1 (de) 2004-02-26
US6090597A (en) 2000-07-18

Similar Documents

Publication Publication Date Title
BR9703475A (pt) Dna recombinante autonomamente replicável em células de bactérias corineformes bactéria corineforme e processo para a produção de l-lisina
BR9606379A (pt) Dna recombinante replicavel em células de bactérias corinformes bactérias corineformes processo para produzir l-lisina
BR9611937A (pt) Processo para a produção de proteínas recombinantes em e colimediante fermentação de densidade elevada de células
BR9306210A (pt) Elétrodo para célula eletrodialítica de fracionamento da água célula eletrodialítica e processo eletrodialítico
BR9705038A (pt) Dna codificador de aspartoquinase iii de bactérias pertencentes ao gênero escherichia dna recombinante microorganismo e processo para produzir um l-amino-ácido
BR9707921A (pt) Processo para manufaturar painéis laterais para artigos descartáveis
BR8807339A (pt) Macrocoloide proteinaceo dispersivo em agua,dispersao aquosa,processo para aquecimento de proteinas coagulaveis e produto
DE59006837D1 (de) Verfahren zur fermentativen Herstellung von Aminosäuren, insbesondere L-Lysin, dafür geeignete Mikroorganismen und rekombinante DNA.
BR9610739A (pt) Célula solar e processo para sua fabricação
BR9506883A (pt) Gene dna recombinante bactéria corineforme processos para produzir l-lizina e para produzir ácido l-glutâmico
BR9508654A (pt) Artigo abrasivo e processo de produção do mesmo
BRPI9801092B8 (pt) processo para a produÇço de fator recombinante viii e meio de cultura de cÉlula.
DE69734183D1 (de) Sonnenzelle und Herstellungsverfahren
BR8707079A (pt) Processo e aparelho de moldar material em chapas termo-amolecido
BR9303324A (pt) Comutador de segmento de carbono planar e processo de fabricacao do mesmo
BR9508960A (pt) Artigo abrasivo e processo de produção do mesmo
PT789767E (pt) Processo para a producao de proteinas de papilomavirus purificadas
BR9505857A (pt) Processo para determinar ponto operacional ideal em amplificador de potência linear processo de treinamento de amplitude e amplificador de potência linear
ITMI940520A0 (it) Processo per la preparazione di fluoropolimero termoplastici contenenti idrogeno
BR9505121A (pt) Processo aparelhagem e célula de combustível
DE69928656D1 (de) Gentechnisch hergestellte hefestämme und deren mutanten zur fermentierung von lignocellulosehydrolysate
BR9509638A (pt) Polímero intumescível na água processo para produção do mesmo e sua utilização
PT956355E (pt) Processo para a imortalizacao de celulas
FI971781A0 (fi) Menetelmä raaka-aineen hyödyntämisen parantamiseksi käymisprosesseissa
PT90768A (pt) Processo para a preparacao de vectores de expressao e de proteinas nao fundidas usando esses vectores em microorganismos

Legal Events

Date Code Title Description
FB34 Technical and formal requirements: requirement - article 34 of industrial property law
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08H Application fees: decision cancelled [chapter 8.8 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1818 DE 08/11/2005 POR TER SIDO APRESENTADA PAPELETA DE ESCLARECIMENTO.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 37, DECIDINDO-SE PELO INDEFIRIMENTO O PRESENTE PEDIDO, TENDO POR BASE O ART. 25 DA LPI 9279 DE 14/05/96.

B12B Appeal against refusal [chapter 12.2 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 22/02/2012, OBSERVADAS AS CONDICOES LEGAIS.

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 22.02.2022