BR9406007A - Construção de DNA, vacina de polinucleotídeos, vetor, processos para proteger contra infecção por vírus influenza humano, para usar um gene de vírus influenza, para induzir respostas imunes contra infecção ou doença provocada por cepas de vírus influenza, composição de construções de ácido nucleico e uso de um gene de vírus influenza humano - Google Patents
Construção de DNA, vacina de polinucleotídeos, vetor, processos para proteger contra infecção por vírus influenza humano, para usar um gene de vírus influenza, para induzir respostas imunes contra infecção ou doença provocada por cepas de vírus influenza, composição de construções de ácido nucleico e uso de um gene de vírus influenza humanoInfo
- Publication number
- BR9406007A BR9406007A BR9406007A BR9406007A BR9406007A BR 9406007 A BR9406007 A BR 9406007A BR 9406007 A BR9406007 A BR 9406007A BR 9406007 A BR9406007 A BR 9406007A BR 9406007 A BR9406007 A BR 9406007A
- Authority
- BR
- Brazil
- Prior art keywords
- influenza virus
- infection
- virus gene
- human influenza
- gene
- Prior art date
Links
- 241000712461 unidentified influenza virus Species 0.000 title 4
- 206010022000 influenza Diseases 0.000 title 2
- 108090000623 proteins and genes Proteins 0.000 title 2
- 108700001237 Nucleic Acid-Based Vaccines Proteins 0.000 title 1
- 238000010276 construction Methods 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000028993 immune response Effects 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 150000007523 nucleic acids Chemical group 0.000 title 1
- 230000009385 viral infection Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3238393A | 1993-03-18 | 1993-03-18 | |
| US8998593A | 1993-07-08 | 1993-07-08 | |
| PCT/US1994/002751 WO1994021797A1 (en) | 1993-03-18 | 1994-03-14 | Nucleic acid pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9406007A true BR9406007A (pt) | 1996-01-02 |
Family
ID=26708344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9406007A BR9406007A (pt) | 1993-03-18 | 1994-03-14 | Construção de DNA, vacina de polinucleotídeos, vetor, processos para proteger contra infecção por vírus influenza humano, para usar um gene de vírus influenza, para induzir respostas imunes contra infecção ou doença provocada por cepas de vírus influenza, composição de construções de ácido nucleico e uso de um gene de vírus influenza humano |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0620277A1 (pt) |
| JP (2) | JP2812352B2 (pt) |
| CN (1) | CN1119458A (pt) |
| AU (1) | AU676258B2 (pt) |
| BG (1) | BG63126B1 (pt) |
| BR (1) | BR9406007A (pt) |
| CA (1) | CA2119175A1 (pt) |
| CZ (1) | CZ290315B6 (pt) |
| DZ (1) | DZ1759A1 (pt) |
| FI (1) | FI954329A (pt) |
| HR (1) | HRP940175A2 (pt) |
| HU (1) | HUT73397A (pt) |
| IL (1) | IL108915A0 (pt) |
| NO (1) | NO953649L (pt) |
| NZ (1) | NZ263680A (pt) |
| PL (1) | PL178626B1 (pt) |
| RO (1) | RO117710B1 (pt) |
| SI (1) | SI9420014A (pt) |
| SK (1) | SK114295A3 (pt) |
| UA (1) | UA42715C2 (pt) |
| WO (1) | WO1994021797A1 (pt) |
| YU (1) | YU12894A (pt) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5849719A (en) | 1993-08-26 | 1998-12-15 | The Regents Of The University Of California | Method for treating allergic lung disease |
| US6911216B1 (en) | 1994-10-12 | 2005-06-28 | Genzyme Corporation | Targeted delivery via biodegradable polymers |
| US5736524A (en) | 1994-11-14 | 1998-04-07 | Merck & Co.,. Inc. | Polynucleotide tuberculosis vaccine |
| DE19512142A1 (de) * | 1995-03-31 | 1996-10-02 | Immuno Ag | Infektiöser cDNA-Klon des Tick-Borne Enzephalitis (TBE)-Virus, davon abgeleiteter rekombinanter Impfstoff und Herstellung desselben sowie ein pharmazeutisches Produkt, das eine replizierbare Nukleinsäure enthält |
| US6019980A (en) | 1995-06-07 | 2000-02-01 | Connaught Laboratories Limited | Nucleic acid respiratory syncytial virus vaccines |
| US6017897A (en) * | 1995-06-07 | 2000-01-25 | Pasteur Merieux Connaught Canada | Nucleic acid respiratory syncytial virus vaccines |
| US6083925A (en) | 1995-06-07 | 2000-07-04 | Connaught Laboratories Limited | Nucleic acid respiratory syncytial virus vaccines |
| US6537776B1 (en) | 1999-06-14 | 2003-03-25 | Diversa Corporation | Synthetic ligation reassembly in directed evolution |
| FR2751225B1 (fr) * | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique aviaire |
| US6204250B1 (en) | 1996-11-22 | 2001-03-20 | The Mount Sinai Medical Center Of The City Of New York | Immunization of infants |
| JP2001515468A (ja) * | 1997-02-14 | 2001-09-18 | メルク エンド カンパニー インコーポレーテッド | ポリヌクレオチドワクチン製剤 |
| UA78180C2 (uk) | 1997-10-03 | 2007-03-15 | Меріаль | Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти |
| US6517843B1 (en) | 1999-08-31 | 2003-02-11 | Merial | Reduction of porcine circovirus-2 viral load with inactivated PCV-2 |
| FR2772047B1 (fr) | 1997-12-05 | 2004-04-09 | Ct Nat D Etudes Veterinaires E | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
| US6686339B1 (en) | 1998-08-20 | 2004-02-03 | Aventis Pasteur Limited | Nucleic acid molecules encoding inclusion membrane protein C of Chlamydia |
| US6693087B1 (en) | 1998-08-20 | 2004-02-17 | Aventis Pasteur Limited | Nucleic acid molecules encoding POMP91A protein of Chlamydia |
| AU5366099A (en) | 1998-08-20 | 2000-03-14 | Connaught Laboratories Limited | Nucleic acid molecules encoding inclusion membrane protein of (chlamydia) |
| US6881723B1 (en) | 1998-11-05 | 2005-04-19 | Powderject Vaccines, Inc. | Nucleic acid constructs |
| US7618797B2 (en) | 1998-12-22 | 2009-11-17 | Pfizer Inc | Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
| US7691389B2 (en) | 1998-12-22 | 2010-04-06 | Pfizer Inc | Infectious cDNA clone of north american porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
| US7022320B1 (en) | 1999-02-09 | 2006-04-04 | Powderject Vaccines, Inc. | Mycobacterium tuberculosis immunization |
| US6943152B1 (en) | 1999-06-10 | 2005-09-13 | Merial | DNA vaccine-PCV |
| JP2001151698A (ja) * | 1999-09-10 | 2001-06-05 | Nichiko Pharmaceutical Co Ltd | インフルエンザワクチン |
| JP4540033B2 (ja) | 1999-10-22 | 2010-09-08 | サノフィ パストゥール リミテッド | 腫瘍抗原に対する免疫応答を誘発および／または増強する方法 |
| US7196066B1 (en) | 1999-11-03 | 2007-03-27 | Powderject Vaccines, Inc. | DNA-vaccines based on constructs derived from the genomes of human and animal pathogens |
| US6852705B2 (en) | 2000-01-21 | 2005-02-08 | Merial | DNA vaccines for farm animals, in particular bovines and porcines |
| US7078388B2 (en) | 2000-01-21 | 2006-07-18 | Merial | DNA vaccines for farm animals, in particular bovines and porcines |
| EP1792995A3 (en) | 2000-05-08 | 2007-06-13 | Sanofi Pasteur Limited | Chlamydia secretory locus orf and uses thereof |
| ATE513913T1 (de) | 2000-05-10 | 2011-07-15 | Sanofi Pasteur Ltd | Durch mage minigene kodierte immunogene polypeptide und ihre verwendungen |
| JP5331340B2 (ja) | 2004-05-18 | 2013-10-30 | バイカル インコーポレイテッド | インフルエンザウィルスワクチン組成物、及びその使用方法 |
| US8202967B2 (en) | 2006-10-27 | 2012-06-19 | Boehringer Ingelheim Vetmedica, Inc. | H5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use |
| JP2010528619A (ja) * | 2007-05-31 | 2010-08-26 | ベクトン・ディキンソン・アンド・カンパニー | インフルエンザａおよびインフルエンザｂウイルスを検出するための配列および方法 |
| US8354230B2 (en) * | 2007-12-21 | 2013-01-15 | Quest Diagnostics Investments Inc. | Multiplex detection assay for influenza and RSV viruses |
| CA2733356C (en) | 2008-08-01 | 2016-06-07 | Gamma Vaccines Pty Limited | Influenza vaccines |
| WO2010127252A2 (en) * | 2009-04-30 | 2010-11-04 | Vanderbilt University | Monoclonal antibodies to influenza h1n1 virus and uses thereof |
| SG168423A1 (en) * | 2009-07-13 | 2011-02-28 | Agency Science Tech & Res | Influenza detection method and kit therefor |
| TWI627281B (zh) | 2009-09-02 | 2018-06-21 | 百靈佳殷格翰家畜藥品公司 | 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物 |
| AR083533A1 (es) | 2010-10-22 | 2013-03-06 | Boehringer Ingelheim Vetmed | Proteinas de hemaglutinina 5 (h5) para el tratamiento y prevencion de las infecciones de gripe |
| AR088028A1 (es) | 2011-08-15 | 2014-05-07 | Boehringer Ingelheim Vetmed | Proteinas h5, de h5n1 para un uso medicinal |
| WO2013033092A2 (en) | 2011-09-03 | 2013-03-07 | Boehringer Ingelheim Vetmedica Gmbh | Streptococcus suis pilus antigens |
| US10383835B2 (en) | 2012-03-14 | 2019-08-20 | The Regents Of The University Of California | Treatment of inflammatory disorders in non-human mammals |
| MX360137B (es) | 2013-02-21 | 2018-10-24 | Boehringer Ingelheim Vetmedica Gmbh | Proteínas h5 del virus de la influenza h5n1 para usarse como un medicamento. |
| EP2976357B1 (en) * | 2013-03-18 | 2018-10-17 | Osivax SAS | Influenza nucleoprotein vaccines |
| BR112016006192A2 (pt) | 2013-09-25 | 2017-09-26 | Zoetis Services Llc | composição de vacina de divergente de pcv2b e métodos de uso |
| JP6395855B2 (ja) | 2014-04-03 | 2018-09-26 | ベーリンガー インゲルハイム フェトメディカ インコーポレイテッド | ブタ流行性下痢ウイルスワクチン |
| DK3344289T3 (da) | 2015-08-31 | 2020-04-14 | Boehringer Ingelheim Vetmedica Gmbh | Pestivirusvacciner mod medfødt tremor |
| JP2018526454A (ja) | 2015-09-16 | 2018-09-13 | ベーリンガー インゲルハイム フェトメディカ インコーポレイテッド | ブタコレラ菌−ネズミチフス菌ワクチン |
| KR102618843B1 (ko) | 2016-09-20 | 2024-01-02 | 베링거잉겔하임베트메디카게엠베하 | 신규한 ehv 삽입 부위 orf70 |
| BR112019005418A2 (pt) | 2016-09-20 | 2019-10-01 | Boehringer Ingelheim Vetmedica Gmbh | novos promotores |
| WO2018057441A1 (en) | 2016-09-20 | 2018-03-29 | Boehringer Ingelheim Vetmedica Gmbh | Canine adenovirus vectors |
| KR102566066B1 (ko) | 2016-09-20 | 2023-08-16 | 베링거잉겔하임베트메디카게엠베하 | 신규한 돼지 인플루엔자 백신 |
| CA3042584A1 (en) | 2016-11-03 | 2018-05-11 | Boehringer Ingelheim Vetmedica Gmbh | Vaccine against porcine parvovirus and porcine reproductive and respiratory syndrome virus and methods of production thereof |
| BR112019009133A2 (pt) | 2016-11-03 | 2019-07-16 | Boehringer Ingelheim Vetmedica Gmbh | vacina contra o parvovírus suíno |
| CN110545841A (zh) | 2017-01-30 | 2019-12-06 | 勃林格殷格翰动物保健美国有限公司 | 猪冠状病毒疫苗 |
| KR20200027479A (ko) | 2017-07-12 | 2020-03-12 | 베링거 인겔하임 애니멀 헬스 유에스에이 인크. | 세네카바이러스 a 면역원성 조성물 및 이의 방법 |
| AR113124A1 (es) | 2017-09-23 | 2020-01-29 | Boehringer Ingelheim Vetmedica Gmbh | Sistema de expresión de paramyxoviridae |
| WO2019092027A1 (en) | 2017-11-09 | 2019-05-16 | Boehringer Ingelheim Vetmedica Gmbh | Sapelovirus immunogenic compositions and uses thereof |
| WO2019162294A1 (en) | 2018-02-23 | 2019-08-29 | Boehringer Ingelheim Vetmedica Gmbh | Recombinant viral vector systems expressing exogenous feline paramyxovirus genes and vaccines made therefrom |
| AU2019239552A1 (en) | 2018-03-19 | 2020-09-10 | Boehringer Ingelheim Vetmedica Gmbh | EHV insertion site UL43 |
| EP3768307A1 (en) | 2018-03-19 | 2021-01-27 | Boehringer Ingelheim Vetmedica GmbH | New ehv with inactivated ul18 and/or ul8 |
| EA202092216A1 (ru) | 2018-03-26 | 2021-06-11 | Бёрингер Ингельхайм Энимал Хелс Ю-Эс-Эй Инк. | Способ получения иммуногенной композиции |
| CN112867505B (zh) | 2018-09-20 | 2024-10-01 | 勃林格殷格翰动物保健有限公司 | 经修饰的pedv刺突蛋白 |
| EP3852800A1 (en) | 2018-09-20 | 2021-07-28 | Boehringer Ingelheim Vetmedica GmbH | Intranasal vector vaccine against porcine epidemic diarrhea |
| IT201900007060A1 (it) | 2019-05-21 | 2020-11-21 | St Superiore Di Sanita | Cellule tumorali ingegnerizzate e loro usi |
| IT201900012540A1 (it) | 2019-07-22 | 2021-01-22 | Humanitas Mirasole Spa | Inibitori di CHI3L1 e loro usi |
| WO2021158878A1 (en) | 2020-02-06 | 2021-08-12 | Boehringer Ingelheim Animal Health USA Inc. | Polypeptides useful for detecting anti-rhabdovirus antibodies |
| EP4225776A1 (en) | 2020-10-05 | 2023-08-16 | Boehringer Ingelheim Vetmedica GmbH | Fusion protein useful for vaccination against rotavirus |
| CN116438202A (zh) | 2020-10-05 | 2023-07-14 | 勃林格殷格翰动物保健美国有限公司 | 包含圆环病毒科衣壳蛋白的融合蛋白及其构成的嵌合病毒样颗粒 |
| AR128992A1 (es) | 2022-04-05 | 2024-07-03 | Boehringer Ingelheim Vetmedica Gmbh | Composición inmunógena útil para la vacunación contra el rotavirus |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL86354A0 (en) * | 1987-05-22 | 1988-11-15 | Orion Yhtymae Oy | Episomal vector for the expression of selected dna fragments coding for optional polypeptides in mammalian cells and methods for the production thereof |
| ATE165516T1 (de) * | 1989-03-21 | 1998-05-15 | Vical Inc | Expression von exogenen polynukleotidsequenzen in wirbeltieren |
| US5643578A (en) * | 1992-03-23 | 1997-07-01 | University Of Massachusetts Medical Center | Immunization by inoculation of DNA transcription unit |
-
1994
- 1994-03-09 EP EP94200605A patent/EP0620277A1/en not_active Withdrawn
- 1994-03-09 IL IL10891594A patent/IL108915A0/xx unknown
- 1994-03-14 SK SK1142-95A patent/SK114295A3/sk unknown
- 1994-03-14 CN CN94191485A patent/CN1119458A/zh active Pending
- 1994-03-14 UA UA95094152A patent/UA42715C2/uk unknown
- 1994-03-14 CZ CZ19952373A patent/CZ290315B6/cs not_active IP Right Cessation
- 1994-03-14 SI SI9420014A patent/SI9420014A/sl not_active IP Right Cessation
- 1994-03-14 WO PCT/US1994/002751 patent/WO1994021797A1/en active IP Right Grant
- 1994-03-14 NZ NZ263680A patent/NZ263680A/en unknown
- 1994-03-14 BR BR9406007A patent/BR9406007A/pt not_active Application Discontinuation
- 1994-03-14 HU HU9502702A patent/HUT73397A/hu unknown
- 1994-03-14 RO RO95-01622A patent/RO117710B1/ro unknown
- 1994-03-14 PL PL94310677A patent/PL178626B1/pl unknown
- 1994-03-16 CA CA002119175A patent/CA2119175A1/en not_active Abandoned
- 1994-03-16 DZ DZ940021A patent/DZ1759A1/fr active
- 1994-03-17 HR HR08/089,985A patent/HRP940175A2/xx not_active Application Discontinuation
- 1994-03-17 AU AU57889/94A patent/AU676258B2/en not_active Ceased
- 1994-03-17 YU YU12894A patent/YU12894A/sh unknown
- 1994-03-18 JP JP6049102A patent/JP2812352B2/ja not_active Expired - Fee Related
-
1995
- 1995-09-14 FI FI954329A patent/FI954329A/fi unknown
- 1995-09-15 NO NO953649A patent/NO953649L/no not_active Application Discontinuation
- 1995-09-18 BG BG100006A patent/BG63126B1/bg unknown
-
1997
- 1997-10-22 JP JP29013797A patent/JP3608642B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FI954329A0 (fi) | 1995-09-14 |
| PL178626B1 (pl) | 2000-05-31 |
| CZ290315B6 (cs) | 2002-07-17 |
| YU12894A (sh) | 1997-12-05 |
| UA42715C2 (uk) | 2001-11-15 |
| PL310677A1 (en) | 1995-12-27 |
| AU5788994A (en) | 1994-09-22 |
| NZ263680A (en) | 1997-05-26 |
| EP0620277A1 (en) | 1994-10-19 |
| BG63126B1 (bg) | 2001-04-30 |
| BG100006A (bg) | 1996-12-31 |
| HRP940175A2 (en) | 1997-04-30 |
| SI9420014A (en) | 1996-08-31 |
| JPH0795888A (ja) | 1995-04-11 |
| HUT73397A (en) | 1996-07-29 |
| HU9502702D0 (en) | 1995-11-28 |
| CA2119175A1 (en) | 1994-09-19 |
| CN1119458A (zh) | 1996-03-27 |
| CZ237395A3 (en) | 1996-02-14 |
| NO953649L (no) | 1995-11-17 |
| JPH10113194A (ja) | 1998-05-06 |
| JP2812352B2 (ja) | 1998-10-22 |
| SK114295A3 (en) | 1996-02-07 |
| WO1994021797A1 (en) | 1994-09-29 |
| JP3608642B2 (ja) | 2005-01-12 |
| DZ1759A1 (fr) | 2002-02-17 |
| FI954329A (fi) | 1995-09-14 |
| IL108915A0 (en) | 1994-06-24 |
| RO117710B1 (ro) | 2002-06-28 |
| NO953649D0 (no) | 1995-09-15 |
| AU676258B2 (en) | 1997-03-06 |
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