BR9106309A - Combinacao de antigenos sinteticos de hepatite c viral (hcv),processo de detectar anticorpos para o virus da hepatite c e estojo para realizar teste - Google Patents
Combinacao de antigenos sinteticos de hepatite c viral (hcv),processo de detectar anticorpos para o virus da hepatite c e estojo para realizar testeInfo
- Publication number
- BR9106309A BR9106309A BR919106309A BR9106309A BR9106309A BR 9106309 A BR9106309 A BR 9106309A BR 919106309 A BR919106309 A BR 919106309A BR 9106309 A BR9106309 A BR 9106309A BR 9106309 A BR9106309 A BR 9106309A
- Authority
- BR
- Brazil
- Prior art keywords
- hepatitis
- hcv
- domain
- viral
- virus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pinball Game Machines (AREA)
- Thermistors And Varistors (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50435290A | 1990-04-04 | 1990-04-04 | |
PCT/US1991/002225 WO1991015771A1 (en) | 1990-04-04 | 1991-03-29 | Combinations of hepatitis c virus (hcv) antigens for use in immunoassays for anti-hcv antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9106309A true BR9106309A (pt) | 1993-04-20 |
Family
ID=24005897
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR919106309A BR9106309A (pt) | 1990-04-04 | 1991-03-29 | Combinacao de antigenos sinteticos de hepatite c viral (hcv),processo de detectar anticorpos para o virus da hepatite c e estojo para realizar teste |
Country Status (25)
Country | Link |
---|---|
EP (2) | EP0693687B2 (pt) |
JP (1) | JP2733138B2 (pt) |
KR (1) | KR100206150B1 (pt) |
AT (2) | ATE139343T1 (pt) |
BG (1) | BG61291B1 (pt) |
BR (1) | BR9106309A (pt) |
CY (1) | CY1881A (pt) |
DE (2) | DE69131488T2 (pt) |
DK (2) | DK0450931T3 (pt) |
ES (2) | ES2088465T3 (pt) |
FI (1) | FI106317B (pt) |
GB (1) | GB2257784B (pt) |
GR (2) | GR3020964T3 (pt) |
HU (1) | HU217025B (pt) |
IE (1) | IE911105A1 (pt) |
IL (2) | IL97741A0 (pt) |
LT (1) | LT3808B (pt) |
LV (2) | LV10344A (pt) |
MY (1) | MY107499A (pt) |
NO (1) | NO310241B1 (pt) |
PL (1) | PL172133B1 (pt) |
RO (1) | RO109916B1 (pt) |
RU (1) | RU2130969C1 (pt) |
UA (1) | UA41266C2 (pt) |
WO (1) | WO1991015771A1 (pt) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7166287B1 (en) | 1989-12-18 | 2007-01-23 | Glaxo Wellcome Inc. | Viral agent |
NZ236491A (en) | 1989-12-18 | 1993-10-26 | Wellcome Found | Post-transfusional non-a non-b hepatitis viral polypeptides, dna, antigenic polypeptides and antibodies to the polypeptides |
KR940000755B1 (ko) * | 1990-02-16 | 1994-01-29 | 유나이티드 바이오메디칼 인코오포레이티드 | Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드 |
US6194140B1 (en) | 1990-04-04 | 2001-02-27 | Chiron Corporation | HCV NS3 protein fragments having helicase activity and improved solubility |
DK0527815T3 (da) * | 1990-04-06 | 2000-11-06 | Genelabs Tech Inc | Hepatitis C-virus-epitop |
CA2049679C (en) * | 1990-08-24 | 2005-06-21 | Sushil G. Devare | Hepatitis c assay utilizing recombinant antigens |
US6274148B1 (en) | 1990-11-08 | 2001-08-14 | Chiron Corporation | Hepatitis C virus asialoglycoproteins |
DE69131882T3 (de) * | 1990-11-08 | 2007-05-24 | Novartis Vaccines and Diagnostics, Inc., Emeryville | Asiloglycoproteine des hepatitis c-virus |
DK0754704T3 (da) * | 1990-12-14 | 2000-04-03 | Innogenetics Nv | Syntetiske antigener til påvisning af antistoffer mod hepatitis c-virus |
US5910404A (en) | 1990-12-14 | 1999-06-08 | Innogenetics N.V. | Synthetic antigens for the detection of antibodies to hepatitis C virus |
US6007982A (en) * | 1990-12-14 | 1999-12-28 | Innogenetics N.V. | Synthetic antigens for the detection of antibodies to hepatitis C virus |
DE4041304A1 (de) * | 1990-12-21 | 1992-06-25 | Mikrogen Molekularbiol Entw | Von strukturproteinen des hepatitis c-virus abgeleitete polypeptide, testkits, die diese polypeptide enthalten und impfstoffe gegen infektionen von hepatitis c-viren |
US5574132A (en) * | 1991-04-05 | 1996-11-12 | Biochem Immunosystems Inc. | Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV) |
AU3063992A (en) * | 1991-11-07 | 1993-06-07 | Dade International Inc. | Epitope mapping ot the c33c region of hcv |
ES2065863T3 (es) * | 1991-11-21 | 2003-09-01 | Common Services Agency | Analisis para la deteccion de virus de la hepatitis c. |
JPH07503615A (ja) * | 1992-02-04 | 1995-04-20 | カイロン コーポレイション | 肝炎療剤 |
GB9203803D0 (en) * | 1992-02-21 | 1992-04-08 | Wellcome Found | A recombinant polypeptide |
UA39944C2 (uk) * | 1992-07-07 | 2001-07-16 | Чірон Корпорейшн | Спосіб визначення ранньої сероконверсії у ссавця-хазяїна до вірусу гепатиту с і набір для використання в способі |
EP0593291A3 (en) * | 1992-10-16 | 1995-03-15 | Evernew Biotech Inc | Non-structural protein of the hepatitis C virus, as well as diagnostic procedure and test kit. |
US6153378A (en) * | 1992-10-16 | 2000-11-28 | Bionova Corporation | Diagnosis of, and vaccination against, a positive stranded RNA virus using an isolated, unprocessed polypeptide encoded by a substantially complete genome of such virus |
JP2778886B2 (ja) * | 1992-10-16 | 1998-07-23 | エバーニュー バイオテック インコーポレイティド | C型肝炎ウィルスのコア抗原タンパク質及びそれを用いての診断方法及びキット |
WO1994013164A1 (en) | 1992-12-10 | 1994-06-23 | Nike International Ltd. | Bonding of rubber to plastic in footwear |
WO1994027153A1 (en) * | 1993-05-10 | 1994-11-24 | Chiron Corporation | Methods of typing hepatitis c virus and reagents for use therein |
DE4428705A1 (de) | 1994-08-12 | 1996-02-15 | Boehringer Mannheim Gmbh | Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus |
JPH0862219A (ja) * | 1994-08-19 | 1996-03-08 | Dainabotsuto Kk | 還元型抗原に対する抗体アッセイ試薬及びそれを使用した測定方法 |
JP3665371B2 (ja) * | 1994-08-31 | 2005-06-29 | 株式会社先端生命科学研究所 | C型肝炎ウイルス感染又はグループ判定のためのエピトープキメラ抗原ペプチド、その製法、及びそれを使用する感染又はグループ判定法 |
CA2172305A1 (en) * | 1995-03-30 | 1996-10-01 | Muneo Aoyama | Multiple antigenic peptide comprising at least two hepatitis c virus-associated peptides |
AU5924396A (en) * | 1995-05-22 | 1996-12-11 | Bionova Corporation | Compositions and methods for the diagnosis of, and vaccinati on against, hepatitis c virus (hcv) |
FR2734639B1 (fr) * | 1995-05-26 | 1997-10-03 | Parteurop | Methode de pronostic de l'evolution d'une infection par le virus de l'hepatite c, et necessaire pour sa mise en oeuvre |
FR2737209B1 (fr) | 1995-07-25 | 1997-09-19 | Bio Merieux | Peptide capable d'etre reconnu par des anticorps reconnaissant l'antigene c33 du virus de l'hepatite c |
US6127116A (en) * | 1995-08-29 | 2000-10-03 | Washington University | Functional DNA clone for hepatitis C virus (HCV) and uses thereof |
JP3715027B2 (ja) | 1996-05-07 | 2005-11-09 | シスメックス株式会社 | C型肝炎ウイルス感染症診断薬 |
US7338759B1 (en) | 1997-03-04 | 2008-03-04 | Washington University | HCV variants |
US7049428B1 (en) | 1998-03-04 | 2006-05-23 | Washington University | HCV variants |
CA2303123C (en) * | 1997-09-22 | 2006-04-11 | Chiron Corporation | Method for detecting antibodies in a sample |
JP2003512598A (ja) * | 1999-07-15 | 2003-04-02 | デパートマント、アヴ、ヘルス、アンド、ヒューマン、サーヴィセズ | C型肝炎に続く肝不全の予測 |
US6562346B1 (en) | 1999-10-27 | 2003-05-13 | Chiron Corporation | Activation of HCV-specific T cells |
US6986892B1 (en) | 1999-11-24 | 2006-01-17 | Chiron Corporation | Immunogenic Hepatitis C virus non-structural polypeptides |
CA2390082C (en) * | 1999-11-24 | 2010-06-29 | Chiron Corporation | Novel hcv non-structural polypeptide |
US7491808B2 (en) | 2000-06-15 | 2009-02-17 | Novartis Vaccines And Diagnostics, Inc. | HCV non-structural protein mutants and uses thereof |
MXPA02012424A (es) | 2000-06-15 | 2003-04-25 | Chiron Corp | Ensayo de combinacion de antigenos/anticuerpos para el virus de hepatitis c. |
US7022830B2 (en) | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
US6680059B2 (en) | 2000-08-29 | 2004-01-20 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
US6858590B2 (en) | 2000-08-17 | 2005-02-22 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
AU9215101A (en) | 2000-08-17 | 2002-02-25 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
FR2839722A1 (fr) | 2002-05-17 | 2003-11-21 | Bio Merieux | Nouvelles compositions peptidiques et leur utilisation notamment dans la preparation de compositions pharmaceutiques actives contre le virus de l'hepatite c |
WO2004021871A2 (en) | 2002-09-09 | 2004-03-18 | Chiron Corporation | Hcv assay |
AP2006003861A0 (en) | 2004-06-09 | 2006-12-31 | Pathogen Removal And Diagnosti | Particles embedded in a porous substrate for removing target analyte from a sample |
JP4005093B2 (ja) * | 2005-05-25 | 2007-11-07 | シスメックス株式会社 | C型肝炎ウイルス感染症診断薬および抗hcv抗体検出方法 |
JP2005274584A (ja) * | 2005-05-25 | 2005-10-06 | Sysmex Corp | C型肝炎ウイルス感染症診断薬の製造方法 |
US7968697B2 (en) | 2005-05-25 | 2011-06-28 | Chrontech Pharma Ab | Hepatitis C virus non-structural NS3/4A fusion gene |
BRPI0708393A2 (pt) * | 2006-03-09 | 2011-05-31 | Transgene Sa | proteìna de fusão não estrutural do vìrus da hepatite c |
US20080227111A1 (en) | 2007-03-16 | 2008-09-18 | Sysmex Corporation | Reagent kit and method for measuring hcv antibody |
EP2185195A2 (en) | 2007-08-16 | 2010-05-19 | Tripep Ab | Immunogen platform |
US20090214593A1 (en) | 2007-08-16 | 2009-08-27 | Tripep Ab | Immunogen platform |
FR2984328B1 (fr) | 2011-12-20 | 2016-12-30 | Bio-Rad Innovations | Procede de detection d'une infection par le virus de l'hepatite c |
US10088483B2 (en) | 2014-10-29 | 2018-10-02 | Abbott Laboratories | Subject anti-HCV antibody detection assays employing NS3 capture peptides |
JP2018124277A (ja) * | 2017-02-02 | 2018-08-09 | 三洋化成工業株式会社 | 粒子含有組成物、免疫測定用試薬、免疫測定方法及び粒子の保存方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US390599A (en) | 1888-10-02 | Tool for weaver s use | ||
US456637A (en) | 1891-07-28 | Fence | ||
SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
US4870008A (en) * | 1983-08-12 | 1989-09-26 | Chiron Corporation | Secretory expression in eukaryotes |
CA1341482C (en) † | 1984-10-31 | 2005-05-10 | Paul A. Luciw | Process for preparing fragments of aids-associated retroviruses |
US4751180A (en) * | 1985-03-28 | 1988-06-14 | Chiron Corporation | Expression using fused genes providing for protein product |
HU216017B (hu) * | 1987-11-18 | 1999-04-28 | Chiron Corp. | Eljárás HCV-1 polipeptidek, HCV-1 polinukleotidok, rekombináns vektorok és gazdasejtek, valamint immunesszé kit, hepatitis C vírusfertőzés elleni vakcinák, a fertőzés kimutatására szolgáló diagnosztikumok előállítására, és immunvizsgálati és vírustenyészt |
HU225068B1 (en) † | 1989-03-17 | 2006-05-29 | Chiron Corp | Process for producing diagnostics and vaccine of nanbh |
NZ236491A (en) * | 1989-12-18 | 1993-10-26 | Wellcome Found | Post-transfusional non-a non-b hepatitis viral polypeptides, dna, antigenic polypeptides and antibodies to the polypeptides |
AU638304B2 (en) † | 1989-12-22 | 1993-06-24 | Abbott Laboratories | Hepatitis c assay |
-
1991
- 1991-03-29 HU HU9203146A patent/HU217025B/hu unknown
- 1991-03-29 RO RO92-01275A patent/RO109916B1/ro unknown
- 1991-03-29 KR KR1019920702437A patent/KR100206150B1/ko not_active IP Right Cessation
- 1991-03-29 UA UA93004190A patent/UA41266C2/uk unknown
- 1991-03-29 WO PCT/US1991/002225 patent/WO1991015771A1/en active IP Right Grant
- 1991-03-29 JP JP3507636A patent/JP2733138B2/ja not_active Expired - Lifetime
- 1991-03-29 BR BR919106309A patent/BR9106309A/pt not_active IP Right Cessation
- 1991-03-29 PL PL91296329A patent/PL172133B1/pl unknown
- 1991-03-29 RU SU5053084A patent/RU2130969C1/ru active
- 1991-04-01 IL IL97741A patent/IL97741A0/xx not_active IP Right Cessation
- 1991-04-01 IL IL170719A patent/IL170719A/en not_active IP Right Cessation
- 1991-04-02 MY MYPI91000551A patent/MY107499A/en unknown
- 1991-04-03 ES ES91302910T patent/ES2088465T3/es not_active Expired - Lifetime
- 1991-04-03 DK DK91302910.4T patent/DK0450931T3/da active
- 1991-04-03 DK DK95114016T patent/DK0693687T4/da active
- 1991-04-03 AT AT91302910T patent/ATE139343T1/de not_active IP Right Cessation
- 1991-04-03 ES ES95114016T patent/ES2134388T5/es not_active Expired - Lifetime
- 1991-04-03 DE DE69131488T patent/DE69131488T2/de not_active Expired - Lifetime
- 1991-04-03 DE DE69120138T patent/DE69120138T2/de not_active Expired - Lifetime
- 1991-04-03 EP EP95114016A patent/EP0693687B2/en not_active Expired - Lifetime
- 1991-04-03 EP EP91302910A patent/EP0450931B1/en not_active Expired - Lifetime
- 1991-04-03 IE IE110591A patent/IE911105A1/en unknown
- 1991-04-03 AT AT95114016T patent/ATE182684T1/de not_active IP Right Cessation
-
1992
- 1992-09-28 FI FI924349A patent/FI106317B/fi active
- 1992-09-28 GB GB9220480A patent/GB2257784B/en not_active Expired - Lifetime
- 1992-10-01 NO NO19923839A patent/NO310241B1/no not_active IP Right Cessation
- 1992-10-02 BG BG96943A patent/BG61291B1/bg unknown
-
1993
- 1993-05-31 LV LV930038D patent/LV10344A/en unknown
- 1993-05-31 LV LVP-93-438.1A patent/LV10344B/en unknown
- 1993-12-30 LT LTIP1747A patent/LT3808B/lt not_active IP Right Cessation
-
1996
- 1996-04-05 CY CY188196A patent/CY1881A/xx unknown
- 1996-09-05 GR GR960402319T patent/GR3020964T3/el unknown
-
1999
- 1999-09-29 GR GR990402455T patent/GR3031361T3/el unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
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FB36 | Technical and formal requirements: requirement - article 36 of industrial property law | ||
FF | Decision: intention to grant | ||
FG9A | Patent or certificate of addition granted | ||
ME | Request for revocation | ||
ME | Request for revocation | ||
B25D | Requested change of name of applicant approved |
Owner name: NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) Free format text: NOME ALTERADO DE: CHIRON CORPORATION |
|
B21A | Patent or certificate of addition expired [chapter 21.1 patent gazette] |
Free format text: PATENTE EXTINTA EM 29/03/2011 |
|
B15K | Others concerning applications: alteration of classification |
Ipc: C07K 14/005 (2006.01), G01N 33/576 (2006.0 |