ES2139571T3 - Ensayo de hepatitis c que utiliza antigenos recombinantes. - Google Patents

Ensayo de hepatitis c que utiliza antigenos recombinantes.

Info

Publication number
ES2139571T3
ES2139571T3 ES91114161T ES91114161T ES2139571T3 ES 2139571 T3 ES2139571 T3 ES 2139571T3 ES 91114161 T ES91114161 T ES 91114161T ES 91114161 T ES91114161 T ES 91114161T ES 2139571 T3 ES2139571 T3 ES 2139571T3
Authority
ES
Spain
Prior art keywords
assay
recombinant antigens
hepatitis
hcv
test
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91114161T
Other languages
English (en)
Inventor
Sushil G Devare
Suresh M Desai
James M Casey
George J Dawson
Richard R Lesniewski
Stephen H Dailey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27075963&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2139571(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2139571T3 publication Critical patent/ES2139571T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

ESTA INVENCION DESCRIBE ANTIGENOS RECOMBINANTES UNICOS, REPRESENTANDO DISTINTAS ZONAS ANTIGENICAS DEL GENOMA HCV QUE SE PUEDEN UTILIZAR COMO REACTANTES PARA DETECTAR ANTICUERPOS Y ANTIGENOS EN FLUIDOS CORPORALES DE INDIVIDUOS EXPUESTOS AL VIRUS DE LA HEPATITIS C (HCV). ESTA INVENCION DESCRIBE TAMBIEN UN ENSAYO PARA DETECTAR LA PRESENCIA DE UN ANTICUERPO PARA UN ANTIGENO HCV EN UNA MUESTRA, AL PONER EN CONTACTO LA MUESTRA CON LOS ANTIGENOS RECOMBINANTES. UNOS FORMATOS DE ENSAYO PREFERENTES, INCLUYEN UN ENSAYO TAMIZADOR, UN ENSAYO DE CONFIRMACION, UN ENSAYO DE TERMINACION O NEUTRALIZACION Y UN ENSAYO DE PUNTO INMUNOLOGICO.
ES91114161T 1990-08-24 1991-08-23 Ensayo de hepatitis c que utiliza antigenos recombinantes. Expired - Lifetime ES2139571T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57282290A 1990-08-24 1990-08-24
US61406990A 1990-11-07 1990-11-07

Publications (1)

Publication Number Publication Date
ES2139571T3 true ES2139571T3 (es) 2000-02-16

Family

ID=27075963

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91114161T Expired - Lifetime ES2139571T3 (es) 1990-08-24 1991-08-23 Ensayo de hepatitis c que utiliza antigenos recombinantes.

Country Status (7)

Country Link
EP (1) EP0472207B1 (es)
JP (1) JP3354579B2 (es)
AT (1) ATE185605T1 (es)
AU (1) AU655592B2 (es)
CA (1) CA2049679C (es)
DE (1) DE69131707T2 (es)
ES (1) ES2139571T3 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683864A (en) * 1987-11-18 1997-11-04 Chiron Corporation Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US5308750A (en) * 1989-12-22 1994-05-03 Abbott Laboratories Monoclonal antibodies to putative HCV E2/NS1 proteins and methods for using same
US5582968A (en) * 1990-02-16 1996-12-10 United Biomedical, Inc. Branched hybrid and cluster peptides effective in diagnosing and detecting non-A, non-B hepatitis
US6312889B1 (en) 1990-04-04 2001-11-06 Chiron Corporation Combinations of hepatitis c virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
KR920004577A (ko) * 1990-08-24 1992-03-27 원본미기재 단백질 합성의 cks 방법
WO1992013892A1 (en) * 1991-01-31 1992-08-20 Abbott Laboratories Monoclonal antibodies to putative hcv envelope region and methods for using same
RO117329B1 (ro) * 1991-06-24 2002-01-30 Chiron Corp Emeryville Polipeptide care contin o secventa a virusului hepatitei c
EP0599913B1 (en) * 1991-08-21 1998-12-02 Abbott Laboratories Monoclonal antibodies to putative hcv ns5 proteins and methos for using same
JP3158177B2 (ja) * 1991-10-08 2001-04-23 国立感染症研究所長 Ｃ型肝炎診断薬
JPH07503615A (ja) * 1992-02-04 1995-04-20 カイロン　コーポレイション 肝炎療剤
GB9203803D0 (en) * 1992-02-21 1992-04-08 Wellcome Found A recombinant polypeptide
JPH06153959A (ja) * 1992-10-16 1994-06-03 Evernew Biotec Inc Ｃ型肝炎ウィルスの非構造タンパク質及びそれを用いての診断方法及びキット
JP2778886B2 (ja) * 1992-10-16 1998-07-23 エバーニュー バイオテック インコーポレイティド Ｃ型肝炎ウィルスのコア抗原タンパク質及びそれを用いての診断方法及びキット
EP0992580B1 (en) * 1993-11-04 2005-03-09 Innogenetics N.V. Immunodominant human T-cell epitopes of Hepatitis C virus
GB9513261D0 (en) * 1995-06-29 1995-09-06 Smithkline Beecham Biolog Vaccines
WO1999061906A2 (en) * 1998-05-28 1999-12-02 Abbott Laboratories Toxoplasma gondii antigens, p35, and uses thereof
US6329157B1 (en) 1998-05-28 2001-12-11 Abbott Laboratories Antigen cocktails and uses thereof
MXPA02012424A (es) 2000-06-15 2003-04-25 Chiron Corp Ensayo de combinacion de antigenos/anticuerpos para el virus de hepatitis c.
WO2004021871A2 (en) 2002-09-09 2004-03-18 Chiron Corporation Hcv assay

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253193B1 (en) * 1986-07-08 1992-10-28 Abbott Laboratories Method for mutagenesis by oligonucleotide-directed repair of a strand break
HU216017B (hu) * 1987-11-18 1999-04-28 Chiron Corp. Eljárás HCV-1 polipeptidek, HCV-1 polinukleotidok, rekombináns vektorok és gazdasejtek, valamint immunesszé kit, hepatitis C vírusfertőzés elleni vakcinák, a fertőzés kimutatására szolgáló diagnosztikumok előállítására, és immunvizsgálati és vírustenyészt
US5124255A (en) * 1988-03-11 1992-06-23 Abbott Laboratories CKS method of protein synthesis
US5075077A (en) * 1988-08-02 1991-12-24 Abbott Laboratories Test card for performing assays
HU225068B1 (en) * 1989-03-17 2006-05-29 Chiron Corp Process for producing diagnostics and vaccine of nanbh
AU638304B2 (en) * 1989-12-22 1993-06-24 Abbott Laboratories Hepatitis c assay
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
HU217025B (hu) * 1990-04-04 1999-11-29 Chiron Corp. Hepatitis C vírus-(HCV) antigénkészítmények az anti-HCV-antitestek kimutatására immunoassay-kben
CA2047792C (en) * 1990-07-26 2002-07-02 Chang Y. Wang Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines
DE4209215A1 (de) * 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
AU2068992A (en) * 1991-08-02 1993-02-04 Akzo N.V. Non-a, non-b peptide
ZA927837B (en) * 1991-10-15 1994-03-11 Akzo Nv Monoclonal antibodiesto hepatitis C virus

Also Published As

Publication number Publication date
JP3354579B2 (ja) 2002-12-09
CA2049679A1 (en) 1992-02-25
EP0472207A2 (en) 1992-02-26
DE69131707T2 (de) 2000-06-08
JPH04281792A (ja) 1992-10-07
AU8277491A (en) 1992-05-07
EP0472207A3 (en) 1992-08-26
ATE185605T1 (de) 1999-10-15
AU655592B2 (en) 1995-01-05
EP0472207B1 (en) 1999-10-13
CA2049679C (en) 2005-06-21
DE69131707D1 (de) 1999-11-18

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