ES2139571T3 - Ensayo de hepatitis c que utiliza antigenos recombinantes. - Google Patents
Ensayo de hepatitis c que utiliza antigenos recombinantes.Info
- Publication number
- ES2139571T3 ES2139571T3 ES91114161T ES91114161T ES2139571T3 ES 2139571 T3 ES2139571 T3 ES 2139571T3 ES 91114161 T ES91114161 T ES 91114161T ES 91114161 T ES91114161 T ES 91114161T ES 2139571 T3 ES2139571 T3 ES 2139571T3
- Authority
- ES
- Spain
- Prior art keywords
- assay
- recombinant antigens
- hepatitis
- hcv
- test
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
ESTA INVENCION DESCRIBE ANTIGENOS RECOMBINANTES UNICOS, REPRESENTANDO DISTINTAS ZONAS ANTIGENICAS DEL GENOMA HCV QUE SE PUEDEN UTILIZAR COMO REACTANTES PARA DETECTAR ANTICUERPOS Y ANTIGENOS EN FLUIDOS CORPORALES DE INDIVIDUOS EXPUESTOS AL VIRUS DE LA HEPATITIS C (HCV). ESTA INVENCION DESCRIBE TAMBIEN UN ENSAYO PARA DETECTAR LA PRESENCIA DE UN ANTICUERPO PARA UN ANTIGENO HCV EN UNA MUESTRA, AL PONER EN CONTACTO LA MUESTRA CON LOS ANTIGENOS RECOMBINANTES. UNOS FORMATOS DE ENSAYO PREFERENTES, INCLUYEN UN ENSAYO TAMIZADOR, UN ENSAYO DE CONFIRMACION, UN ENSAYO DE TERMINACION O NEUTRALIZACION Y UN ENSAYO DE PUNTO INMUNOLOGICO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57282290A | 1990-08-24 | 1990-08-24 | |
US61406990A | 1990-11-07 | 1990-11-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2139571T3 true ES2139571T3 (es) | 2000-02-16 |
Family
ID=27075963
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91114161T Expired - Lifetime ES2139571T3 (es) | 1990-08-24 | 1991-08-23 | Ensayo de hepatitis c que utiliza antigenos recombinantes. |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0472207B1 (es) |
JP (1) | JP3354579B2 (es) |
AT (1) | ATE185605T1 (es) |
AU (1) | AU655592B2 (es) |
CA (1) | CA2049679C (es) |
DE (1) | DE69131707T2 (es) |
ES (1) | ES2139571T3 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5683864A (en) * | 1987-11-18 | 1997-11-04 | Chiron Corporation | Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies |
US5350671A (en) * | 1987-11-18 | 1994-09-27 | Chiron Corporation | HCV immunoassays employing C domain antigens |
US5308750A (en) * | 1989-12-22 | 1994-05-03 | Abbott Laboratories | Monoclonal antibodies to putative HCV E2/NS1 proteins and methods for using same |
US5582968A (en) * | 1990-02-16 | 1996-12-10 | United Biomedical, Inc. | Branched hybrid and cluster peptides effective in diagnosing and detecting non-A, non-B hepatitis |
US5712087A (en) * | 1990-04-04 | 1998-01-27 | Chiron Corporation | Immunoassays for anti-HCV antibodies employing combinations of hepatitis C virus (HCV) antigens |
KR920004577A (ko) * | 1990-08-24 | 1992-03-27 | 원본미기재 | 단백질 합성의 cks 방법 |
JP3483555B2 (ja) * | 1991-01-31 | 2004-01-06 | アボット・ラボラトリーズ | 推定hcvエンベロープ領域に対するモノクローナル抗体およびその使用方法 |
DE69232871T2 (de) * | 1991-06-24 | 2003-05-08 | Chiron Corp | Polypeptide des hepatitis c-virus (hiv) |
DE69227776T2 (de) * | 1991-08-21 | 1999-07-01 | Abbott Lab | Monoklonale antikörper gegen mutmassliche hepatitis c-virus ns5-proteine und ihre anwendungsmethoden |
JP3158177B2 (ja) * | 1991-10-08 | 2001-04-23 | 国立感染症研究所長 | C型肝炎診断薬 |
ES2174845T3 (es) * | 1992-02-04 | 2002-11-16 | Chiron Corp | Terapeutica de la hepatitis. |
GB9203803D0 (en) * | 1992-02-21 | 1992-04-08 | Wellcome Found | A recombinant polypeptide |
JPH06153959A (ja) * | 1992-10-16 | 1994-06-03 | Evernew Biotec Inc | C型肝炎ウィルスの非構造タンパク質及びそれを用いての診断方法及びキット |
JP2778886B2 (ja) * | 1992-10-16 | 1998-07-23 | エバーニュー バイオテック インコーポレイティド | C型肝炎ウィルスのコア抗原タンパク質及びそれを用いての診断方法及びキット |
DK0992580T3 (da) * | 1993-11-04 | 2005-07-11 | Innogenetics Nv | Epitoper på human T-celler, som er immundominante for hepatitis C-virus |
GB9513261D0 (en) * | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
CA2333598C (en) * | 1998-05-28 | 2009-10-13 | Abbott Laboratories | Toxoplasma gondii antigens, p35, and uses thereof |
US6329157B1 (en) | 1998-05-28 | 2001-12-11 | Abbott Laboratories | Antigen cocktails and uses thereof |
AU2001272945A1 (en) * | 2000-06-15 | 2001-12-24 | Chiron Corporation | Immunoassays for anti-hcv antibodies |
EP1546414B1 (en) | 2002-09-09 | 2008-10-08 | Novartis Vaccines and Diagnostics, Inc. | Hcv assay |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3782365T2 (de) * | 1986-07-08 | 1993-04-22 | Abbott Lab | Verfahren fuer die mutagenese durch eine oligonukleotidgeleitete reparatur eines strangbruchs. |
EP0318216B2 (en) * | 1987-11-18 | 2001-08-29 | Chiron Corporation | NANBV diagnostics |
US5124255A (en) * | 1988-03-11 | 1992-06-23 | Abbott Laboratories | CKS method of protein synthesis |
US5075077A (en) * | 1988-08-02 | 1991-12-24 | Abbott Laboratories | Test card for performing assays |
HUT54896A (en) * | 1989-03-17 | 1991-04-29 | Chiron Corp | Process for producing aquous diagnosticum and vaccine of nanbv |
AU638304B2 (en) * | 1989-12-22 | 1993-06-24 | Abbott Laboratories | Hepatitis c assay |
KR940000755B1 (ko) * | 1990-02-16 | 1994-01-29 | 유나이티드 바이오메디칼 인코오포레이티드 | Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드 |
JP2733138B2 (ja) * | 1990-04-04 | 1998-03-30 | カイロン コーポレイション | 抗hcv抗体の免疫アッセイに使用するc型肝炎ウイルス(hcv)抗原の組合せ |
CA2047792C (en) * | 1990-07-26 | 2002-07-02 | Chang Y. Wang | Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines |
DE4209215A1 (de) * | 1991-07-04 | 1993-01-07 | Boehringer Mannheim Gmbh | Hcv peptidantigene und verfahren zur bestimmung von hcv |
FI923448A (fi) * | 1991-08-02 | 1993-02-03 | Akzo Nv | Non-a, non-b-peptid |
ZA927837B (en) * | 1991-10-15 | 1994-03-11 | Akzo Nv | Monoclonal antibodiesto hepatitis C virus |
-
1991
- 1991-08-22 CA CA002049679A patent/CA2049679C/en not_active Expired - Lifetime
- 1991-08-23 AT AT91114161T patent/ATE185605T1/de not_active IP Right Cessation
- 1991-08-23 AU AU82774/91A patent/AU655592B2/en not_active Ceased
- 1991-08-23 ES ES91114161T patent/ES2139571T3/es not_active Expired - Lifetime
- 1991-08-23 EP EP91114161A patent/EP0472207B1/en not_active Expired - Lifetime
- 1991-08-23 DE DE69131707T patent/DE69131707T2/de not_active Expired - Lifetime
- 1991-08-26 JP JP24058791A patent/JP3354579B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP3354579B2 (ja) | 2002-12-09 |
JPH04281792A (ja) | 1992-10-07 |
EP0472207A2 (en) | 1992-02-26 |
DE69131707D1 (de) | 1999-11-18 |
CA2049679C (en) | 2005-06-21 |
EP0472207A3 (en) | 1992-08-26 |
DE69131707T2 (de) | 2000-06-08 |
AU8277491A (en) | 1992-05-07 |
CA2049679A1 (en) | 1992-02-25 |
AU655592B2 (en) | 1995-01-05 |
ATE185605T1 (de) | 1999-10-15 |
EP0472207B1 (en) | 1999-10-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2139571T3 (es) | Ensayo de hepatitis c que utiliza antigenos recombinantes. | |
FI20021626A (fi) | Immuunimäärityksen reagenssi ja menetelmä hepatiitti C-viruksen (HCV) vasta-aineiden havaitsemiseksi | |
ES2080099T3 (es) | Ensayo para la hepatitis c. | |
GR940300008T1 (es) | ||
ATE135466T1 (de) | Durch silber intensiviertes, auf goldmarkierung beruhendes immuntestverfahren | |
ES2145746T3 (es) | Analisis de deteccion de hepatitis c. | |
KR920701481A (ko) | 장을 통해 전염되는 비a비b형 간염 바이러스 병원체 및 그것의 특유한 에피토프 | |
DE69230812D1 (de) | Verfahren zum Nachweis einer Rinderdiarrhoe- virusinfektion, für ein durch eine Infektion mit diesem Virus induziertes Eiweiss kodierende Nukleotidsequenz, sowie daraus abgeleitete rekombinante Eiweisse und Antigene | |
BR0200986A (pt) | Ensaio de combinação anticorpo - antìgeno da hepatite c para a detecção precoce da infecção | |
KR880014376A (ko) | Hiv 특이 항원 영역의 모노클로날 항체 및 그 용법 | |
Gershon et al. | Determination of immunity to varicella using an enzyme-linked-immunosorbent-assay | |
CA2116026A1 (en) | Hepatitis c assay utilizing recombinant antigens to c-100 region | |
ES2156858T3 (es) | Reactivo de diagnostico para hepatitis c. | |
ATE143142T1 (de) | Immunoassay zum nachweis von antikörpern gegen hiv | |
AP9901515A0 (en) | Reagent system and kit or detecting HIV infected cells. | |
Constantine et al. | Concordance of tests to detect antibodies to hepatitis C virus | |
RU2370776C2 (ru) | Набор антигенов для раздельного выявления антител к структурным и неструктурным белкам вируса гепатита с | |
Ireland | Development of enzyme-linked immunosorbent assays for antibodies to hepatitis B virus. | |
BR0206887A (pt) | Reagentes para a detecção simult nea de antìgenos e anticorpos de núcleo de do vìrus da hepatite c (hcv) | |
Tang et al. | Detection of measles virus specific IgM antibody with ELISA. | |
Cavuslu et al. | ELSEVIER Journal of Virological Methods 58 (1996) 213-214 | |
UA36086A (uk) | Тест-система для підтвердження наявності антитіл проти вірусу гепатиту с (іфа-п-hcv) | |
TH32713C3 (th) | วิธีสำหรับการวิเคราะห์แอนติบอดีและอุปกรณ์การวิเคราะห์แอนติบอดี |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 472207 Country of ref document: ES |