DK0693687T3 - Kombinationer af hepatitis C-virus (HCV)-antigener til anvendelse i immunoassays for anti-HCV-antistoffer - Google Patents

Kombinationer af hepatitis C-virus (HCV)-antigener til anvendelse i immunoassays for anti-HCV-antistoffer

Info

Publication number
DK0693687T3
DK0693687T3 DK95114016T DK95114016T DK0693687T3 DK 0693687 T3 DK0693687 T3 DK 0693687T3 DK 95114016 T DK95114016 T DK 95114016T DK 95114016 T DK95114016 T DK 95114016T DK 0693687 T3 DK0693687 T3 DK 0693687T3
Authority
DK
Denmark
Prior art keywords
hcv
domain
combinations
antigens
antigen
Prior art date
Application number
DK95114016T
Other languages
English (en)
Other versions
DK0693687T4 (da
Inventor
Michael Houghton
George Kuo
Qui-Lim Choo
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24005897&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0693687(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corp filed Critical Chiron Corp
Application granted granted Critical
Publication of DK0693687T3 publication Critical patent/DK0693687T3/da
Publication of DK0693687T4 publication Critical patent/DK0693687T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Thermistors And Varistors (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK95114016T 1990-04-04 1991-04-03 Kombinationer af hepatitis C-virus (HCV)-antigener til anvendelse i immunoassays for anti-HCV-antistoffer DK0693687T4 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50435290A 1990-04-04 1990-04-04

Publications (2)

Publication Number Publication Date
DK0693687T3 true DK0693687T3 (da) 1999-11-29
DK0693687T4 DK0693687T4 (da) 2008-09-22

Family

ID=24005897

Family Applications (2)

Application Number Title Priority Date Filing Date
DK91302910.4T DK0450931T3 (da) 1990-04-04 1991-04-03 Kombinationer af hepatitis C-virus (HCV)-antigener til anvendelse i immunoassays for anti-HCV-antistoffer
DK95114016T DK0693687T4 (da) 1990-04-04 1991-04-03 Kombinationer af hepatitis C-virus (HCV)-antigener til anvendelse i immunoassays for anti-HCV-antistoffer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK91302910.4T DK0450931T3 (da) 1990-04-04 1991-04-03 Kombinationer af hepatitis C-virus (HCV)-antigener til anvendelse i immunoassays for anti-HCV-antistoffer

Country Status (25)

Country Link
EP (2) EP0693687B2 (da)
JP (1) JP2733138B2 (da)
KR (1) KR100206150B1 (da)
AT (2) ATE182684T1 (da)
BG (1) BG61291B1 (da)
BR (1) BR9106309A (da)
CY (1) CY1881A (da)
DE (2) DE69131488T2 (da)
DK (2) DK0450931T3 (da)
ES (2) ES2088465T3 (da)
FI (1) FI106317B (da)
GB (1) GB2257784B (da)
GR (2) GR3020964T3 (da)
HU (1) HU217025B (da)
IE (1) IE911105A1 (da)
IL (2) IL170719A (da)
LT (1) LT3808B (da)
LV (2) LV10344B (da)
MY (1) MY107499A (da)
NO (1) NO310241B1 (da)
PL (1) PL172133B1 (da)
RO (1) RO109916B1 (da)
RU (1) RU2130969C1 (da)
UA (1) UA41266C2 (da)
WO (1) WO1991015771A1 (da)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9002779A (nl) 1989-12-18 1991-07-16 Wellcome Found Viraal middel.
US7166287B1 (en) 1989-12-18 2007-01-23 Glaxo Wellcome Inc. Viral agent
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
US6194140B1 (en) 1990-04-04 2001-02-27 Chiron Corporation HCV NS3 protein fragments having helicase activity and improved solubility
AU660925B2 (en) * 1990-04-06 1995-07-13 Genelabs Technologies, Inc. Hepatitis C virus epitopes
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens
DK0556292T4 (da) * 1990-11-08 2006-12-27 Novartis Vaccines & Diagnostic Hepatitis C virus asialoglycoproteiner
US6274148B1 (en) 1990-11-08 2001-08-14 Chiron Corporation Hepatitis C virus asialoglycoproteins
US6007982A (en) * 1990-12-14 1999-12-28 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
US5910404A (en) 1990-12-14 1999-06-08 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
ES2138784T3 (es) * 1990-12-14 2000-01-16 Innogenetics Nv Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.
DE4041304A1 (de) * 1990-12-21 1992-06-25 Mikrogen Molekularbiol Entw Von strukturproteinen des hepatitis c-virus abgeleitete polypeptide, testkits, die diese polypeptide enthalten und impfstoffe gegen infektionen von hepatitis c-viren
US5574132A (en) * 1991-04-05 1996-11-12 Biochem Immunosystems Inc. Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV)
CA2099883A1 (en) * 1991-11-07 1993-05-08 John A. Kink Epitope mapping of the c33c region of hcv
US5763159A (en) * 1991-11-21 1998-06-09 Common Services Agency Hepatitis-C virus testing
WO1993015207A2 (en) * 1992-02-04 1993-08-05 Viagene, Inc. Hepatitis therapeutics
GB9203803D0 (en) * 1992-02-21 1992-04-08 Wellcome Found A recombinant polypeptide
UA39944C2 (uk) * 1992-07-07 2001-07-16 Чірон Корпорейшн Спосіб визначення ранньої сероконверсії у ссавця-хазяїна до вірусу гепатиту с і набір для використання в способі
EP0593291A3 (en) * 1992-10-16 1995-03-15 Evernew Biotech Inc Non-structural protein of the hepatitis C virus, as well as diagnostic procedure and test kit.
JP2778886B2 (ja) * 1992-10-16 1998-07-23 エバーニュー バイオテック インコーポレイティド Ｃ型肝炎ウィルスのコア抗原タンパク質及びそれを用いての診断方法及びキット
US6153378A (en) * 1992-10-16 2000-11-28 Bionova Corporation Diagnosis of, and vaccination against, a positive stranded RNA virus using an isolated, unprocessed polypeptide encoded by a substantially complete genome of such virus
WO1994013164A1 (en) 1992-12-10 1994-06-23 Nike International Ltd. Bonding of rubber to plastic in footwear
ATE281647T1 (de) 1993-05-10 2004-11-15 Chiron Corp Verfahren zur typisierung von hepatitis c viren und dafür zu verwendende reagenzien
DE4428705A1 (de) 1994-08-12 1996-02-15 Boehringer Mannheim Gmbh Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus
JPH0862219A (ja) * 1994-08-19 1996-03-08 Dainabotsuto Kk 還元型抗原に対する抗体アッセイ試薬及びそれを使用した測定方法
JP3665371B2 (ja) * 1994-08-31 2005-06-29 株式会社先端生命科学研究所 Ｃ型肝炎ウイルス感染又はグループ判定のためのエピトープキメラ抗原ペプチド、その製法、及びそれを使用する感染又はグループ判定法
CA2172305A1 (en) * 1995-03-30 1996-10-01 Muneo Aoyama Multiple antigenic peptide comprising at least two hepatitis c virus-associated peptides
AU5924396A (en) * 1995-05-22 1996-12-11 Bionova Corporation Compositions and methods for the diagnosis of, and vaccinati on against, hepatitis c virus (hcv)
FR2734639B1 (fr) * 1995-05-26 1997-10-03 Parteurop Methode de pronostic de l'evolution d'une infection par le virus de l'hepatite c, et necessaire pour sa mise en oeuvre
FR2737209B1 (fr) 1995-07-25 1997-09-19 Bio Merieux Peptide capable d'etre reconnu par des anticorps reconnaissant l'antigene c33 du virus de l'hepatite c
US6127116A (en) * 1995-08-29 2000-10-03 Washington University Functional DNA clone for hepatitis C virus (HCV) and uses thereof
JP3715027B2 (ja) 1996-05-07 2005-11-09 シスメックス株式会社 Ｃ型肝炎ウイルス感染症診断薬
US7049428B1 (en) 1998-03-04 2006-05-23 Washington University HCV variants
US7338759B1 (en) 1997-03-04 2008-03-04 Washington University HCV variants
DK1021719T3 (da) * 1997-09-22 2007-06-18 Novartis Vaccines & Diagnostic Fremgangsmåde til påvisning af antistoffer i en pröve
AU6098900A (en) * 1999-07-15 2001-02-05 Bayer Corporation The use of specific antibody titers to predict hepatic failure in people infected with hepatitis c virus
EP1232267B1 (en) 1999-10-27 2013-03-20 Novartis Vaccines and Diagnostics, Inc. Activation of hcv-specific t cells
US6986892B1 (en) 1999-11-24 2006-01-17 Chiron Corporation Immunogenic Hepatitis C virus non-structural polypeptides
CN101684146A (zh) * 1999-11-24 2010-03-31 诺华疫苗和诊断公司 新颖的hcv非结构多肽
BRPI0111731C1 (pt) 2000-06-15 2021-07-27 Chiron Corp suporte sólido de imunoensaio, métodos de detecção de infecção pelo vírus da hepatite c (hcv) em uma amostra biológica, e de produção de um suporte sólido de imunoensaio, e, kit de teste de imunodiagnóstico
US7491808B2 (en) 2000-06-15 2009-02-17 Novartis Vaccines And Diagnostics, Inc. HCV non-structural protein mutants and uses thereof
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
AU2001290178A1 (en) 2000-08-17 2002-02-25 Tripep Ab A hepatitis c virus non-structural ns3/4a fusion gene
US6680059B2 (en) 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US6858590B2 (en) 2000-08-17 2005-02-22 Tripep Ab Vaccines containing ribavirin and methods of use thereof
FR2839722A1 (fr) * 2002-05-17 2003-11-21 Bio Merieux Nouvelles compositions peptidiques et leur utilisation notamment dans la preparation de compositions pharmaceutiques actives contre le virus de l'hepatite c
ATE410693T1 (de) 2002-09-09 2008-10-15 Novartis Vaccines & Diagnostic Hcv-test
MXPA06014480A (es) * 2004-06-09 2007-03-21 Pathogen Removal And Diagnosti Particulas incluidas en un substrato poroso para la remocion de analitos objetivo de una muestra.
EP1888751A2 (en) 2005-05-25 2008-02-20 Tripep Ab A hepatitis c virus non-structural ns3/4a fusion gene
JP4005093B2 (ja) * 2005-05-25 2007-11-07 シスメックス株式会社 Ｃ型肝炎ウイルス感染症診断薬および抗ｈｃｖ抗体検出方法
JP2005274584A (ja) * 2005-05-25 2005-10-06 Sysmex Corp Ｃ型肝炎ウイルス感染症診断薬の製造方法
WO2007101657A1 (en) 2006-03-09 2007-09-13 Transgene S.A. Hepatitis c virus non structural fusion protein
EP1978365B1 (en) 2007-03-16 2010-08-25 Sysmex Corporation Reagent kit and method for measuring HCV antibody
EP2185195A2 (en) 2007-08-16 2010-05-19 Tripep Ab Immunogen platform
US20090214593A1 (en) 2007-08-16 2009-08-27 Tripep Ab Immunogen platform
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
KR102441636B1 (ko) * 2014-10-29 2022-09-13 아보트 러보러터리즈 Ns3 포획 펩타이드를 사용한 대상체 항-hcv 항체 검출 검정
JP2018124277A (ja) * 2017-02-02 2018-08-09 三洋化成工業株式会社 粒子含有組成物、免疫測定用試薬、免疫測定方法及び粒子の保存方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US390599A (en) 1888-10-02 Tool for weaver s use
US456637A (en) 1891-07-28 Fence
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4870008A (en) * 1983-08-12 1989-09-26 Chiron Corporation Secretory expression in eukaryotes
CA1341482C (en) † 1984-10-31 2005-05-10 Paul A. Luciw Process for preparing fragments of aids-associated retroviruses
US4751180A (en) * 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
ES2012739T5 (es) * 1987-11-18 2001-12-01 Chiron Corp Diagnosticos para nanbv.
WO1990011089A1 (en) † 1989-03-17 1990-10-04 Chiron Corporation Nanbv diagnostics and vaccines
NL9002779A (nl) * 1989-12-18 1991-07-16 Wellcome Found Viraal middel.
AU638304B2 (en) † 1989-12-22 1993-06-24 Abbott Laboratories Hepatitis c assay

Also Published As

Publication number Publication date
GB9220480D0 (en) 1992-11-25
ES2088465T3 (es) 1996-08-16
EP0693687A1 (en) 1996-01-24
EP0693687B2 (en) 2008-06-04
CY1881A (en) 1996-04-05
JP2733138B2 (ja) 1998-03-30
FI924349A (fi) 1992-09-28
EP0450931A1 (en) 1991-10-09
JPH05508219A (ja) 1993-11-18
GB2257784B (en) 1995-01-04
KR100206150B1 (ko) 1999-07-01
ATE139343T1 (de) 1996-06-15
EP0450931B1 (en) 1996-06-12
IE911105A1 (en) 1991-10-09
GB2257784A (en) 1993-01-20
DE69120138D1 (de) 1996-07-18
DK0450931T3 (da) 1996-07-01
BR9106309A (pt) 1993-04-20
ATE182684T1 (de) 1999-08-15
GR3020964T3 (en) 1996-12-31
DK0693687T4 (da) 2008-09-22
DE69120138T2 (de) 1996-11-14
LT3808B (en) 1996-03-25
RU2130969C1 (ru) 1999-05-27
AU639560B2 (en) 1993-07-29
RO109916B1 (ro) 1995-07-28
LV10344B (en) 1996-02-20
BG61291B1 (en) 1997-04-30
IL170719A (en) 2011-04-28
FI106317B (fi) 2001-01-15
MY107499A (en) 1995-12-30
LV10344A (en) 1994-10-20
PL172133B1 (pl) 1997-08-29
EP0693687B1 (en) 1999-07-28
WO1991015771A1 (en) 1991-10-17
NO310241B1 (no) 2001-06-11
HU217025B (hu) 1999-11-29
ES2134388T5 (es) 2008-12-01
BG96943A (bg) 1993-12-24
NO923839D0 (no) 1992-10-01
DE69131488D1 (de) 1999-09-02
NO923839L (no) 1992-11-19
FI924349A0 (fi) 1992-09-28
IL97741A0 (en) 1992-06-21
AU7651091A (en) 1991-10-30
DE69131488T2 (de) 1999-11-18
HU9203146D0 (en) 1992-12-28
GR3031361T3 (en) 2000-01-31
HUT62706A (en) 1993-05-28
ES2134388T3 (es) 1999-10-01
UA41266C2 (uk) 2001-09-17
LTIP1747A (en) 1995-07-25

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