LT3808B - Combinations of hepatitis c virus (hcv) antigens for use in immunoassays for anti-hcv antibodies - Google Patents

Combinations of hepatitis c virus (hcv) antigens for use in immunoassays for anti-hcv antibodies Download PDF

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Publication number
LT3808B
LT3808B LTIP1747A LTIP1747A LT3808B LT 3808 B LT3808 B LT 3808B LT IP1747 A LTIP1747 A LT IP1747A LT IP1747 A LTIP1747 A LT IP1747A LT 3808 B LT3808 B LT 3808B
Authority
LT
Lithuania
Prior art keywords
hcv
domain
antigen
cvh
avh
Prior art date
Application number
LTIP1747A
Other languages
English (en)
Lithuanian (lt)
Inventor
Michael Houghton
Qui-Lim Choo
George Kuo
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24005897&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT3808(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of LTIP1747A publication Critical patent/LTIP1747A/xx
Publication of LT3808B publication Critical patent/LT3808B/lt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pinball Game Machines (AREA)
  • Thermistors And Varistors (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
LTIP1747A 1990-04-04 1993-12-30 Combinations of hepatitis c virus (hcv) antigens for use in immunoassays for anti-hcv antibodies LT3808B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50435290A 1990-04-04 1990-04-04

Publications (2)

Publication Number Publication Date
LTIP1747A LTIP1747A (en) 1995-07-25
LT3808B true LT3808B (en) 1996-03-25

Family

ID=24005897

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP1747A LT3808B (en) 1990-04-04 1993-12-30 Combinations of hepatitis c virus (hcv) antigens for use in immunoassays for anti-hcv antibodies

Country Status (25)

Country Link
EP (2) EP0693687B2 (da)
JP (1) JP2733138B2 (da)
KR (1) KR100206150B1 (da)
AT (2) ATE139343T1 (da)
BG (1) BG61291B1 (da)
BR (1) BR9106309A (da)
CY (1) CY1881A (da)
DE (2) DE69131488T2 (da)
DK (2) DK0450931T3 (da)
ES (2) ES2088465T3 (da)
FI (1) FI106317B (da)
GB (1) GB2257784B (da)
GR (2) GR3020964T3 (da)
HU (1) HU217025B (da)
IE (1) IE911105A1 (da)
IL (2) IL97741A0 (da)
LT (1) LT3808B (da)
LV (2) LV10344A (da)
MY (1) MY107499A (da)
NO (1) NO310241B1 (da)
PL (1) PL172133B1 (da)
RO (1) RO109916B1 (da)
RU (1) RU2130969C1 (da)
UA (1) UA41266C2 (da)
WO (1) WO1991015771A1 (da)

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KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
US6194140B1 (en) 1990-04-04 2001-02-27 Chiron Corporation HCV NS3 protein fragments having helicase activity and improved solubility
DK0527815T3 (da) * 1990-04-06 2000-11-06 Genelabs Tech Inc Hepatitis C-virus-epitop
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens
US6274148B1 (en) 1990-11-08 2001-08-14 Chiron Corporation Hepatitis C virus asialoglycoproteins
DE69131882T3 (de) * 1990-11-08 2007-05-24 Novartis Vaccines and Diagnostics, Inc., Emeryville Asiloglycoproteine des hepatitis c-virus
DK0754704T3 (da) * 1990-12-14 2000-04-03 Innogenetics Nv Syntetiske antigener til påvisning af antistoffer mod hepatitis c-virus
US5910404A (en) 1990-12-14 1999-06-08 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
US6007982A (en) * 1990-12-14 1999-12-28 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
DE4041304A1 (de) * 1990-12-21 1992-06-25 Mikrogen Molekularbiol Entw Von strukturproteinen des hepatitis c-virus abgeleitete polypeptide, testkits, die diese polypeptide enthalten und impfstoffe gegen infektionen von hepatitis c-viren
US5574132A (en) * 1991-04-05 1996-11-12 Biochem Immunosystems Inc. Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV)
AU3063992A (en) * 1991-11-07 1993-06-07 Dade International Inc. Epitope mapping ot the c33c region of hcv
ES2065863T3 (es) * 1991-11-21 2003-09-01 Common Services Agency Analisis para la deteccion de virus de la hepatitis c.
JPH07503615A (ja) * 1992-02-04 1995-04-20 カイロン コーポレイション 肝炎療剤
GB9203803D0 (en) * 1992-02-21 1992-04-08 Wellcome Found A recombinant polypeptide
UA39944C2 (uk) * 1992-07-07 2001-07-16 Чірон Корпорейшн Спосіб визначення ранньої сероконверсії у ссавця-хазяїна до вірусу гепатиту с і набір для використання в способі
EP0593291A3 (en) * 1992-10-16 1995-03-15 Evernew Biotech Inc Non-structural protein of the hepatitis C virus, as well as diagnostic procedure and test kit.
US6153378A (en) * 1992-10-16 2000-11-28 Bionova Corporation Diagnosis of, and vaccination against, a positive stranded RNA virus using an isolated, unprocessed polypeptide encoded by a substantially complete genome of such virus
JP2778886B2 (ja) * 1992-10-16 1998-07-23 エバーニュー バイオテック インコーポレイティド C型肝炎ウィルスのコア抗原タンパク質及びそれを用いての診断方法及びキット
WO1994013164A1 (en) 1992-12-10 1994-06-23 Nike International Ltd. Bonding of rubber to plastic in footwear
WO1994027153A1 (en) * 1993-05-10 1994-11-24 Chiron Corporation Methods of typing hepatitis c virus and reagents for use therein
DE4428705A1 (de) 1994-08-12 1996-02-15 Boehringer Mannheim Gmbh Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus
JPH0862219A (ja) * 1994-08-19 1996-03-08 Dainabotsuto Kk 還元型抗原に対する抗体アッセイ試薬及びそれを使用した測定方法
JP3665371B2 (ja) * 1994-08-31 2005-06-29 株式会社先端生命科学研究所 C型肝炎ウイルス感染又はグループ判定のためのエピトープキメラ抗原ペプチド、その製法、及びそれを使用する感染又はグループ判定法
CA2172305A1 (en) * 1995-03-30 1996-10-01 Muneo Aoyama Multiple antigenic peptide comprising at least two hepatitis c virus-associated peptides
AU5924396A (en) * 1995-05-22 1996-12-11 Bionova Corporation Compositions and methods for the diagnosis of, and vaccinati on against, hepatitis c virus (hcv)
FR2734639B1 (fr) * 1995-05-26 1997-10-03 Parteurop Methode de pronostic de l'evolution d'une infection par le virus de l'hepatite c, et necessaire pour sa mise en oeuvre
FR2737209B1 (fr) 1995-07-25 1997-09-19 Bio Merieux Peptide capable d'etre reconnu par des anticorps reconnaissant l'antigene c33 du virus de l'hepatite c
US6127116A (en) * 1995-08-29 2000-10-03 Washington University Functional DNA clone for hepatitis C virus (HCV) and uses thereof
JP3715027B2 (ja) 1996-05-07 2005-11-09 シスメックス株式会社 C型肝炎ウイルス感染症診断薬
US7338759B1 (en) 1997-03-04 2008-03-04 Washington University HCV variants
US7049428B1 (en) 1998-03-04 2006-05-23 Washington University HCV variants
CA2303123C (en) * 1997-09-22 2006-04-11 Chiron Corporation Method for detecting antibodies in a sample
JP2003512598A (ja) * 1999-07-15 2003-04-02 デパートマント、アヴ、ヘルス、アンド、ヒューマン、サーヴィセズ C型肝炎に続く肝不全の予測
US6562346B1 (en) 1999-10-27 2003-05-13 Chiron Corporation Activation of HCV-specific T cells
US6986892B1 (en) 1999-11-24 2006-01-17 Chiron Corporation Immunogenic Hepatitis C virus non-structural polypeptides
CA2390082C (en) * 1999-11-24 2010-06-29 Chiron Corporation Novel hcv non-structural polypeptide
US7491808B2 (en) 2000-06-15 2009-02-17 Novartis Vaccines And Diagnostics, Inc. HCV non-structural protein mutants and uses thereof
MXPA02012424A (es) 2000-06-15 2003-04-25 Chiron Corp Ensayo de combinacion de antigenos/anticuerpos para el virus de hepatitis c.
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
US6680059B2 (en) 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US6858590B2 (en) 2000-08-17 2005-02-22 Tripep Ab Vaccines containing ribavirin and methods of use thereof
AU9215101A (en) 2000-08-17 2002-02-25 Tripep Ab Vaccines containing ribavirin and methods of use thereof
FR2839722A1 (fr) 2002-05-17 2003-11-21 Bio Merieux Nouvelles compositions peptidiques et leur utilisation notamment dans la preparation de compositions pharmaceutiques actives contre le virus de l'hepatite c
WO2004021871A2 (en) 2002-09-09 2004-03-18 Chiron Corporation Hcv assay
AP2006003861A0 (en) 2004-06-09 2006-12-31 Pathogen Removal And Diagnosti Particles embedded in a porous substrate for removing target analyte from a sample
JP4005093B2 (ja) * 2005-05-25 2007-11-07 シスメックス株式会社 C型肝炎ウイルス感染症診断薬および抗hcv抗体検出方法
JP2005274584A (ja) * 2005-05-25 2005-10-06 Sysmex Corp C型肝炎ウイルス感染症診断薬の製造方法
US7968697B2 (en) 2005-05-25 2011-06-28 Chrontech Pharma Ab Hepatitis C virus non-structural NS3/4A fusion gene
BRPI0708393A2 (pt) * 2006-03-09 2011-05-31 Transgene Sa proteìna de fusão não estrutural do vìrus da hepatite c
US20080227111A1 (en) 2007-03-16 2008-09-18 Sysmex Corporation Reagent kit and method for measuring hcv antibody
EP2185195A2 (en) 2007-08-16 2010-05-19 Tripep Ab Immunogen platform
US20090214593A1 (en) 2007-08-16 2009-08-27 Tripep Ab Immunogen platform
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
US10088483B2 (en) 2014-10-29 2018-10-02 Abbott Laboratories Subject anti-HCV antibody detection assays employing NS3 capture peptides
JP2018124277A (ja) * 2017-02-02 2018-08-09 三洋化成工業株式会社 粒子含有組成物、免疫測定用試薬、免疫測定方法及び粒子の保存方法

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US4255431A (en) 1978-04-14 1981-03-10 Aktiebolaget Hassle Gastric acid secretion inhibiting substituted 2-(2-benzimidazolyl)-pyridines, pharmaceutical preparations containing same, and method for inhibiting gastric acid secretion
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Also Published As

Publication number Publication date
GR3020964T3 (en) 1996-12-31
HUT62706A (en) 1993-05-28
DK0693687T4 (da) 2008-09-22
LTIP1747A (en) 1995-07-25
EP0693687B1 (en) 1999-07-28
RU2130969C1 (ru) 1999-05-27
GB2257784B (en) 1995-01-04
DE69120138D1 (de) 1996-07-18
NO923839D0 (no) 1992-10-01
MY107499A (en) 1995-12-30
UA41266C2 (uk) 2001-09-17
FI924349A0 (fi) 1992-09-28
ES2134388T5 (es) 2008-12-01
NO310241B1 (no) 2001-06-11
DE69131488T2 (de) 1999-11-18
DK0693687T3 (da) 1999-11-29
KR100206150B1 (ko) 1999-07-01
EP0450931B1 (en) 1996-06-12
CY1881A (en) 1996-04-05
GB2257784A (en) 1993-01-20
BG96943A (bg) 1993-12-24
ATE139343T1 (de) 1996-06-15
FI106317B (fi) 2001-01-15
EP0693687B2 (en) 2008-06-04
DE69131488D1 (de) 1999-09-02
EP0693687A1 (en) 1996-01-24
WO1991015771A1 (en) 1991-10-17
IE911105A1 (en) 1991-10-09
RO109916B1 (ro) 1995-07-28
IL170719A (en) 2011-04-28
DE69120138T2 (de) 1996-11-14
DK0450931T3 (da) 1996-07-01
LV10344B (en) 1996-02-20
GR3031361T3 (en) 2000-01-31
IL97741A0 (en) 1992-06-21
ES2134388T3 (es) 1999-10-01
BG61291B1 (en) 1997-04-30
ATE182684T1 (de) 1999-08-15
AU7651091A (en) 1991-10-30
FI924349A (fi) 1992-09-28
BR9106309A (pt) 1993-04-20
NO923839L (no) 1992-11-19
HU9203146D0 (en) 1992-12-28
HU217025B (hu) 1999-11-29
EP0450931A1 (en) 1991-10-09
LV10344A (en) 1994-10-20
ES2088465T3 (es) 1996-08-16
GB9220480D0 (en) 1992-11-25
JPH05508219A (ja) 1993-11-18
JP2733138B2 (ja) 1998-03-30
AU639560B2 (en) 1993-07-29
PL172133B1 (pl) 1997-08-29

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PD9A Change of patent owner

Owner name: NOVARTIS VACCINES & DIAGNOSTICS, INC, US

Effective date: 20071228

MK9A Expiry of a patent

Effective date: 20131230