DK0649537T4 - Immunoassays til anti-HCV-antistoffer, ved anvendelse af antigener med konformationelle epitoper - Google Patents
Immunoassays til anti-HCV-antistoffer, ved anvendelse af antigener med konformationelle epitoperInfo
- Publication number
- DK0649537T4 DK0649537T4 DK93916942T DK93916942T DK0649537T4 DK 0649537 T4 DK0649537 T4 DK 0649537T4 DK 93916942 T DK93916942 T DK 93916942T DK 93916942 T DK93916942 T DK 93916942T DK 0649537 T4 DK0649537 T4 DK 0649537T4
- Authority
- DK
- Denmark
- Prior art keywords
- antigens
- conformational epitopes
- hcv
- immunoassays
- hcv antibodies
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Communicable Diseases (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91075992A | 1992-07-07 | 1992-07-07 | |
PCT/US1993/006309 WO1994001778A1 (en) | 1992-07-07 | 1993-07-02 | Immunoassays for anti-hcv antibodies using antigens with conformational epitopes |
Publications (2)
Publication Number | Publication Date |
---|---|
DK0649537T3 DK0649537T3 (da) | 2002-06-17 |
DK0649537T4 true DK0649537T4 (da) | 2006-04-10 |
Family
ID=25429280
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93916942T DK0649537T4 (da) | 1992-07-07 | 1993-07-02 | Immunoassays til anti-HCV-antistoffer, ved anvendelse af antigener med konformationelle epitoper |
Country Status (19)
Country | Link |
---|---|
US (1) | US20020150883A1 (da) |
EP (1) | EP0649537B2 (da) |
JP (2) | JP3490085B2 (da) |
AT (1) | ATE216779T1 (da) |
AU (1) | AU685059B2 (da) |
CA (1) | CA2139645C (da) |
CZ (1) | CZ291951B6 (da) |
DE (1) | DE69331845T3 (da) |
DK (1) | DK0649537T4 (da) |
ES (1) | ES2171414T5 (da) |
FI (1) | FI110546B (da) |
HU (1) | HUT70473A (da) |
NO (1) | NO321185B1 (da) |
PL (1) | PL174686B1 (da) |
PT (1) | PT649537E (da) |
RU (1) | RU2126158C1 (da) |
SK (1) | SK284556B6 (da) |
UA (1) | UA39944C2 (da) |
WO (1) | WO1994001778A1 (da) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6274148B1 (en) * | 1990-11-08 | 2001-08-14 | Chiron Corporation | Hepatitis C virus asialoglycoproteins |
US5882852A (en) * | 1993-06-29 | 1999-03-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates |
US7070790B1 (en) | 1993-06-29 | 2006-07-04 | The United States Of America As Represented By The Department Of Health And Human Services | Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines |
DK0721505T4 (da) | 1994-07-29 | 2006-08-14 | Innogenetics Nv | Rensede hepatitis C-virus-kappeproteiner til diagnostisk og terapeutisk anvendelse |
DE4428705A1 (de) * | 1994-08-12 | 1996-02-15 | Boehringer Mannheim Gmbh | Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus |
US5707385A (en) * | 1994-11-16 | 1998-01-13 | Advanced Cardiovascular Systems, Inc. | Drug loaded elastic membrane and method for delivery |
WO1996041196A1 (en) * | 1995-06-07 | 1996-12-19 | Abbott Laboratories | Method for detection of antibody to hepatitis c virus second envelope glycoprotein |
US6514731B1 (en) | 1996-05-24 | 2003-02-04 | Chiron Corporation | Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens |
WO2000026673A1 (en) * | 1998-11-03 | 2000-05-11 | Abbott Laboratories | Methods of detecting chronic infection caused by hcv |
US6815160B1 (en) | 1999-07-28 | 2004-11-09 | Chiron Corporation | Hepatitis C viral antigen immunoassay detection systems |
ATE352785T1 (de) * | 1999-07-28 | 2007-02-15 | Novartis Vaccines & Diagnostic | Verfahren zum nachweis von hepatitis c antigenen |
BRPI0111731C1 (pt) | 2000-06-15 | 2021-07-27 | Chiron Corp | suporte sólido de imunoensaio, métodos de detecção de infecção pelo vírus da hepatite c (hcv) em uma amostra biológica, e de produção de um suporte sólido de imunoensaio, e, kit de teste de imunodiagnóstico |
EP1829891B1 (en) | 2000-06-15 | 2012-12-26 | Novartis Vaccines and Diagnostics, Inc. | Immunoassays for Anti-HCV Antibodies |
AR045702A1 (es) | 2001-10-03 | 2005-11-09 | Chiron Corp | Composiciones de adyuvantes. |
CA2498228C (en) | 2002-09-09 | 2011-03-22 | Chiron Corporation | Hcv assay |
WO2004071414A2 (en) * | 2003-02-05 | 2004-08-26 | Genzyme Corporation | Therapeutic anti-hcv (al9) compounds |
US7731967B2 (en) | 2003-04-30 | 2010-06-08 | Novartis Vaccines And Diagnostics, Inc. | Compositions for inducing immune responses |
EP1799868B1 (en) * | 2004-08-27 | 2012-01-18 | Novartis Vaccines and Diagnostics, Inc. | Hcv non-structural protein mutants and uses thereof |
CA2661492A1 (en) | 2006-08-25 | 2008-02-28 | Novartis Ag | Hcv fusion polypeptides |
US8815253B2 (en) | 2007-12-07 | 2014-08-26 | Novartis Ag | Compositions for inducing immune responses |
FR2984328B1 (fr) | 2011-12-20 | 2016-12-30 | Bio-Rad Innovations | Procede de detection d'une infection par le virus de l'hepatite c |
CA2906407A1 (en) | 2013-03-14 | 2014-09-18 | Abbott Laboratories | Hcv ns3 recombinant antigens and mutants thereof for improved antibody detection |
JP6739329B2 (ja) | 2013-03-14 | 2020-08-12 | アボット・ラボラトリーズAbbott Laboratories | Hcvコア脂質結合ドメインモノクローナル抗体 |
MX362075B (es) | 2013-03-14 | 2019-01-07 | Abbott Lab | Ensayo de combinación de antígeno-anticuerpo del virus de la hepatitis c (vhc) y métodos y composiciones para usarlo. |
JP6859314B2 (ja) | 2015-03-27 | 2021-04-14 | オーソ−クリニカル・ダイアグノスティックス・インコーポレイテッドOrtho−Clinical Diagnostics, Inc. | Hcv ns4a/改変されたns3ポリペプチド及びその使用 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4855224A (en) * | 1984-03-09 | 1989-08-08 | Genentech, Inc. | Molecularly cloned diagnostic product and method of use |
CN1049686C (zh) | 1987-11-18 | 2000-02-23 | 希龙股份有限公司 | 非a和非b肝炎病毒的诊断及疫苗 |
KR0185373B1 (ko) | 1989-03-17 | 1999-05-01 | 로버트 피. 블랙버언 | Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용 |
US5372928A (en) * | 1989-09-15 | 1994-12-13 | Chiron Corporation | Hepatitis C virus isolates |
DK298190A (da) * | 1989-12-18 | 1991-06-19 | Wellcome Found | Viralt middel |
ZA912040B (en) * | 1990-03-30 | 1991-12-24 | Akzo Nv | Peptides immunochemically reactive with antibodies directed against hepatitis non-a,non-b virus |
UA41266C2 (uk) * | 1990-04-04 | 2001-09-17 | Чірон Корпорейшн | Комбінація послідовностей епітопів вірусу гепатиту с (hcv), спосіб виявлення антитіл до вірусу гепатиту с (hcv), набір для виконання аналізу при виявленні антитіл до антигену гепатиту с (hcv) |
US5443965A (en) * | 1990-04-06 | 1995-08-22 | Genelabs Incorporated | Hepatitis C virus epitopes |
CA2045326A1 (en) * | 1990-06-25 | 1991-12-26 | Hiroto Okayama | Non-a, non-b, hepatitis virus particles |
EP0468657A3 (en) * | 1990-07-09 | 1992-02-05 | Tonen Corporation | Non-a non b hepatitis-specific antigen and its use in hepatitus diagnosis |
JPH06504431A (ja) * | 1990-11-08 | 1994-05-26 | カイロン コーポレイション | C型肝炎ウイルスアシアロ糖タンパク質 |
IT1249684B (it) * | 1991-07-19 | 1995-03-09 | Sorin Biomedica Spa | Epitopi della proteina env del virus dell'epatite c. |
DE69333269T2 (de) * | 1992-01-31 | 2004-07-29 | Abbott Laboratories, Abbott Park | Expressionssystem in säugetieren für hcv-proteine |
US5587285A (en) * | 1992-01-31 | 1996-12-24 | University Of Texas System | Generation serological assay for monitoring HIV exposure |
-
1993
- 1993-02-07 UA UA95028108A patent/UA39944C2/uk unknown
- 1993-07-02 JP JP50344094A patent/JP3490085B2/ja not_active Expired - Lifetime
- 1993-07-02 DK DK93916942T patent/DK0649537T4/da active
- 1993-07-02 WO PCT/US1993/006309 patent/WO1994001778A1/en active IP Right Grant
- 1993-07-02 CA CA002139645A patent/CA2139645C/en not_active Expired - Lifetime
- 1993-07-02 PT PT93916942T patent/PT649537E/pt unknown
- 1993-07-02 AT AT93916942T patent/ATE216779T1/de active
- 1993-07-02 CZ CZ19956A patent/CZ291951B6/cs not_active IP Right Cessation
- 1993-07-02 DE DE69331845T patent/DE69331845T3/de not_active Expired - Lifetime
- 1993-07-02 ES ES93916942T patent/ES2171414T5/es not_active Expired - Lifetime
- 1993-07-02 PL PL93307178A patent/PL174686B1/pl unknown
- 1993-07-02 SK SK4-95A patent/SK284556B6/sk not_active IP Right Cessation
- 1993-07-02 RU RU94046284A patent/RU2126158C1/ru active
- 1993-07-02 HU HU9500008A patent/HUT70473A/hu not_active Application Discontinuation
- 1993-07-02 AU AU46629/93A patent/AU685059B2/en not_active Expired
- 1993-07-02 EP EP93916942A patent/EP0649537B2/en not_active Expired - Lifetime
-
1995
- 1995-01-02 NO NO19950006A patent/NO321185B1/no not_active IP Right Cessation
- 1995-01-02 FI FI950002A patent/FI110546B/fi not_active IP Right Cessation
-
2001
- 2001-08-02 US US09/920,879 patent/US20020150883A1/en not_active Abandoned
-
2003
- 2003-04-14 JP JP2003109573A patent/JP2003329687A/ja not_active Withdrawn
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