DE69331845D1 - Immunoassays für anti-hcv-antikörper unter verwendung von antigenen mit konformationsepitopen - Google Patents

Immunoassays für anti-hcv-antikörper unter verwendung von antigenen mit konformationsepitopen

Info

Publication number
DE69331845D1
DE69331845D1 DE69331845T DE69331845T DE69331845D1 DE 69331845 D1 DE69331845 D1 DE 69331845D1 DE 69331845 T DE69331845 T DE 69331845T DE 69331845 T DE69331845 T DE 69331845T DE 69331845 D1 DE69331845 D1 DE 69331845D1
Authority
DE
Germany
Prior art keywords
antigens
hcv
sepitopes
immunoassays
information
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69331845T
Other languages
English (en)
Other versions
DE69331845T2 (de
DE69331845T3 (de
Inventor
Y Chien
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25429280&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69331845(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of DE69331845D1 publication Critical patent/DE69331845D1/de
Publication of DE69331845T2 publication Critical patent/DE69331845T2/de
Application granted granted Critical
Publication of DE69331845T3 publication Critical patent/DE69331845T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Communicable Diseases (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
DE69331845T 1992-07-07 1993-07-02 Immunoassays für anti-hcv-antikörper unter verwendung von antigenen mit konformationsepitopen Expired - Lifetime DE69331845T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91075992A 1992-07-07 1992-07-07
US910759 1992-07-07
PCT/US1993/006309 WO1994001778A1 (en) 1992-07-07 1993-07-02 Immunoassays for anti-hcv antibodies using antigens with conformational epitopes

Publications (3)

Publication Number Publication Date
DE69331845D1 true DE69331845D1 (de) 2002-06-06
DE69331845T2 DE69331845T2 (de) 2002-08-14
DE69331845T3 DE69331845T3 (de) 2006-10-05

Family

ID=25429280

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331845T Expired - Lifetime DE69331845T3 (de) 1992-07-07 1993-07-02 Immunoassays für anti-hcv-antikörper unter verwendung von antigenen mit konformationsepitopen

Country Status (19)

Country Link
US (1) US20020150883A1 (de)
EP (1) EP0649537B2 (de)
JP (2) JP3490085B2 (de)
AT (1) ATE216779T1 (de)
AU (1) AU685059B2 (de)
CA (1) CA2139645C (de)
CZ (1) CZ291951B6 (de)
DE (1) DE69331845T3 (de)
DK (1) DK0649537T4 (de)
ES (1) ES2171414T5 (de)
FI (1) FI110546B (de)
HU (1) HUT70473A (de)
NO (1) NO321185B1 (de)
PL (1) PL174686B1 (de)
PT (1) PT649537E (de)
RU (1) RU2126158C1 (de)
SK (1) SK284556B6 (de)
UA (1) UA39944C2 (de)
WO (1) WO1994001778A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274148B1 (en) * 1990-11-08 2001-08-14 Chiron Corporation Hepatitis C virus asialoglycoproteins
US7070790B1 (en) 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US5882852A (en) * 1993-06-29 1999-03-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates
JPH09503396A (ja) * 1994-07-29 1997-04-08 インノジェネティクス・エヌ・ブイ 診断用及び治療用の精製ｃ型肝炎ウイルスエンベロープ蛋白
DE4428705A1 (de) * 1994-08-12 1996-02-15 Boehringer Mannheim Gmbh Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus
US5707385A (en) * 1994-11-16 1998-01-13 Advanced Cardiovascular Systems, Inc. Drug loaded elastic membrane and method for delivery
EP0836708A1 (de) * 1995-06-07 1998-04-22 Abbott Laboratories Nachwisverfahren für antikörper gegen das zweite hüllprotein des hepatitis c virus
US6514731B1 (en) 1996-05-24 2003-02-04 Chiron Corporation Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens
WO2000026673A1 (en) * 1998-11-03 2000-05-11 Abbott Laboratories Methods of detecting chronic infection caused by hcv
US6815160B1 (en) 1999-07-28 2004-11-09 Chiron Corporation Hepatitis C viral antigen immunoassay detection systems
JP5498637B2 (ja) * 1999-07-28 2014-05-21 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド Ｃ型肝炎ウイルス抗原免疫アッセイ検出システム
AU2001272945A1 (en) * 2000-06-15 2001-12-24 Chiron Corporation Immunoassays for anti-hcv antibodies
EP1829891B1 (de) 2000-06-15 2012-12-26 Novartis Vaccines and Diagnostics, Inc. Immuntests für Anti-HCV-Antikörper
AR045702A1 (es) 2001-10-03 2005-11-09 Chiron Corp Composiciones de adyuvantes.
EP1546414B1 (de) 2002-09-09 2008-10-08 Novartis Vaccines and Diagnostics, Inc. Hcv-test
WO2004071414A2 (en) * 2003-02-05 2004-08-26 Genzyme Corporation Therapeutic anti-hcv (al9) compounds
US7731967B2 (en) 2003-04-30 2010-06-08 Novartis Vaccines And Diagnostics, Inc. Compositions for inducing immune responses
WO2006024020A2 (en) 2004-08-27 2006-03-02 Novartis Vaccines And Diagnostics Inc. Hcv non-structural protein mutants and uses thereof
JP5474547B2 (ja) 2006-08-25 2014-04-16 ノバルティス アーゲー Ｈｃｖ融合ポリペプチド
US8815253B2 (en) 2007-12-07 2014-08-26 Novartis Ag Compositions for inducing immune responses
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
MX2015012824A (es) 2013-03-14 2016-06-24 Abbott Lab Antigenos recombinantes ns3 del vhc y mutantes de los mismos para la deteccion mejorada de anticuerpos.
CN105228649B (zh) 2013-03-14 2019-01-18 雅培制药有限公司 Hcv抗原-抗体组合测定和方法以及用在其中的组合物
US9371374B2 (en) 2013-03-14 2016-06-21 Abbott Laboratories HCV core lipid binding domain monoclonal antibodies
WO2016160046A1 (en) 2015-03-27 2016-10-06 Ortho-Clinical Diagnostics, Inc. Hcv ns4a/modified ns3 polypeptides and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855224A (en) * 1984-03-09 1989-08-08 Genentech, Inc. Molecularly cloned diagnostic product and method of use
EP0318216B2 (de) 1987-11-18 2001-08-29 Chiron Corporation NANBV-Diagnostika
HUT54896A (en) 1989-03-17 1991-04-29 Chiron Corp Process for producing aquous diagnosticum and vaccine of nanbv
US5372928A (en) * 1989-09-15 1994-12-13 Chiron Corporation Hepatitis C virus isolates
IT1242183B (it) * 1989-12-18 1994-02-16 Wellcome Found Polipeptidi del virus dell'epatite non-a e non-b, post-trasfusionali, procedimento di produzione e corredo per il saggio dei relativi acidi nucleici virali.
ZA912040B (en) * 1990-03-30 1991-12-24 Akzo Nv Peptides immunochemically reactive with antibodies directed against hepatitis non-a,non-b virus
JP2733138B2 (ja) * 1990-04-04 1998-03-30 カイロン コーポレイション 抗ｈｃｖ抗体の免疫アッセイに使用するｃ型肝炎ウイルス（ｈｃｖ）抗原の組合せ
US5443965A (en) * 1990-04-06 1995-08-22 Genelabs Incorporated Hepatitis C virus epitopes
CA2045326A1 (en) * 1990-06-25 1991-12-26 Hiroto Okayama Non-a, non-b, hepatitis virus particles
EP0468657A3 (en) * 1990-07-09 1992-02-05 Tonen Corporation Non-a non b hepatitis-specific antigen and its use in hepatitus diagnosis
JPH06504431A (ja) * 1990-11-08 1994-05-26 カイロン　コーポレイション Ｃ型肝炎ウイルスアシアロ糖タンパク質
IT1249684B (it) * 1991-07-19 1995-03-09 Sorin Biomedica Spa Epitopi della proteina env del virus dell'epatite c.
WO1993015193A1 (en) * 1992-01-31 1993-08-05 Abbott Laboratories Mammalian expression systems for hcv proteins
US5587285A (en) * 1992-01-31 1996-12-24 University Of Texas System Generation serological assay for monitoring HIV exposure

Also Published As

Publication number Publication date
ES2171414T3 (es) 2002-09-16
PL174686B1 (pl) 1998-08-31
PL307178A1 (en) 1995-05-02
HU9500008D0 (en) 1995-03-28
WO1994001778A1 (en) 1994-01-20
FI950002A0 (fi) 1995-01-02
CZ291951B6 (cs) 2003-06-18
EP0649537B2 (de) 2006-02-22
SK284556B6 (sk) 2005-06-02
UA39944C2 (uk) 2001-07-16
NO950006D0 (no) 1995-01-02
DK0649537T4 (da) 2006-04-10
CA2139645C (en) 2003-02-11
SK495A3 (en) 1995-07-11
RU2126158C1 (ru) 1999-02-10
CZ695A3 (en) 1996-03-13
FI950002A (fi) 1995-02-27
DE69331845T2 (de) 2002-08-14
AU685059B2 (en) 1998-01-15
DK0649537T3 (da) 2002-06-17
CA2139645A1 (en) 1994-01-20
FI110546B (fi) 2003-02-14
US20020150883A1 (en) 2002-10-17
EP0649537B1 (de) 2002-04-24
NO321185B1 (no) 2006-04-03
ATE216779T1 (de) 2002-05-15
DE69331845T3 (de) 2006-10-05
AU4662993A (en) 1994-01-31
NO950006L (no) 1995-02-24
ES2171414T5 (es) 2006-09-01
HUT70473A (en) 1995-10-30
PT649537E (pt) 2002-09-30
JP2003329687A (ja) 2003-11-19
RU94046284A (ru) 1997-02-27
JPH07509060A (ja) 1995-10-05
JP3490085B2 (ja) 2004-01-26
EP0649537A1 (de) 1995-04-26

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS,INC.(N.D.GES, US