KR880000794A - 샌드위치식 면역분석용 시약 복합물 - Google Patents

샌드위치식 면역분석용 시약 복합물 Download PDF

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Publication number
KR880000794A
KR880000794A KR1019870006204A KR870006204A KR880000794A KR 880000794 A KR880000794 A KR 880000794A KR 1019870006204 A KR1019870006204 A KR 1019870006204A KR 870006204 A KR870006204 A KR 870006204A KR 880000794 A KR880000794 A KR 880000794A
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South Korea
Prior art keywords
complex
labeled antibody
immunoglobulin
antibody
sandwich immunoassay
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KR1019870006204A
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English (en)
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KR960016337B1 (ko
Inventor
시계오 아오야기
미요꼬 구스미
아끼라 마쓰유끼
노부오 오오시마
Original Assignee
이노구마 도끼히사
가부시끼가이샤 메이덴샤
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Priority claimed from JP61142885A external-priority patent/JPS62299763A/ja
Priority claimed from JP62082512A external-priority patent/JPS63145960A/ja
Priority claimed from JP62149324A external-priority patent/JPS63313067A/ja
Application filed by 이노구마 도끼히사, 가부시끼가이샤 메이덴샤 filed Critical 이노구마 도끼히사
Publication of KR880000794A publication Critical patent/KR880000794A/ko
Application granted granted Critical
Publication of KR960016337B1 publication Critical patent/KR960016337B1/ko

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/563Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

내용 없음

Description

샌드위치식 면역분석용 시약 복합물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제 1 도는 화학발광 강도와 AFP양 간의 관계를 나타내는 그래프임. 제 2 도는 IgG 구조를 나타내는 개락도임. 제 3 도는 주어진 실시예에 대한 비특이적 결합율을 플롯트한 그래프임.

Claims (6)

  1. 반응 용액 존재하에 항원과 반응하여 항원을 표지화 항체와 고상 항체 사이에 포획하는 표지화 항체 및 고상 항체를 사용하고, 표지화 항체는 토끼로 부터 유래되고, 고상 항체는 염소로 부터 유래됨을 특징으로 하는 개선된 샌드위치식 면역분석용 고상 항체, 표지화 항체와 반응 용액의 복합물.
  2. 제 1 항에 있어서, 표지화 항체가 면역글로불린 G를 포함하는 복합물.
  3. 제 2 항에 있어서, 표지화 항체가 면역글로불린 G로부터 생선된 Fab' 단편을 포함하는 복합물.
  4. 제 1 항에 있어서, 반응 용액이 정상 기니아픽 혈청과 혼합된 복합물.
  5. 제 4 항에 있어서, 표지화 항체가 면역글로불린 G를 포함하는 복합물.
  6. 제 5 항에 있어서, 표지화 항체가 면역글로불린 G로부터 생선된 Fab'단편을 포함하는 복합물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019870006204A 1986-06-20 1987-06-19 샌드위치식 면역분석용 키트 KR960016337B1 (ko)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP142885 1986-06-20
JP61-142885 1986-06-20
JP61142885A JPS62299763A (ja) 1986-06-20 1986-06-20 免疫学的測定試薬
JP62-82512 1987-04-03
JP62082512A JPS63145960A (ja) 1986-06-23 1987-04-03 標識抗体の非特異的吸着抑制薬
JP82512 1987-04-03
JP62-149324 1987-06-16
JP62149324A JPS63313067A (ja) 1987-06-16 1987-06-16 抗原の測定試薬

Publications (2)

Publication Number Publication Date
KR880000794A true KR880000794A (ko) 1988-03-29
KR960016337B1 KR960016337B1 (ko) 1996-12-09

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870006204A KR960016337B1 (ko) 1986-06-20 1987-06-19 샌드위치식 면역분석용 키트

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KR (1) KR960016337B1 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101888769B1 (ko) * 2016-12-15 2018-08-16 성균관대학교산학협력단 바이오센서, 이의 제조방법, 이를 포함하는 표적물질 검출용 키트 및 이를 이용한 표적물질 검출방법

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Publication number Publication date
KR960016337B1 (ko) 1996-12-09

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