BR112018011636B1 - Sistema de residência gástrico para liberação sustentada de um agente terapêutico - Google Patents
Sistema de residência gástrico para liberação sustentada de um agente terapêutico Download PDFInfo
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- BR112018011636B1 BR112018011636B1 BR112018011636-0A BR112018011636A BR112018011636B1 BR 112018011636 B1 BR112018011636 B1 BR 112018011636B1 BR 112018011636 A BR112018011636 A BR 112018011636A BR 112018011636 B1 BR112018011636 B1 BR 112018011636B1
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- Prior art keywords
- polymer
- gastric residence
- elastomer
- therapeutic agent
- intercomponent
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- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
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- C08G18/12—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step using two or more compounds having active hydrogen in the first polymerisation step
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
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- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
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- C08G18/72—Polyisocyanates or polyisothiocyanates
- C08G18/73—Polyisocyanates or polyisothiocyanates acyclic
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
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- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
Landscapes
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- Botany (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
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- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US201562264811P | 2015-12-08 | 2015-12-08 | |
| US62/264,811 | 2015-12-08 | ||
| PCT/US2016/065453 WO2017100367A1 (en) | 2015-12-08 | 2016-12-07 | Geometric configurations for gastric residence systems |
Publications (2)
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| BR112018011636A2 BR112018011636A2 (pt) | 2018-11-27 |
| BR112018011636B1 true BR112018011636B1 (pt) | 2024-03-12 |
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| BR112018011636-0A BR112018011636B1 (pt) | 2015-12-08 | 2016-12-07 | Sistema de residência gástrico para liberação sustentada de um agente terapêutico |
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| EP (2) | EP4302817A3 (enExample) |
| JP (1) | JP7030052B2 (enExample) |
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| CN (2) | CN120827528A (enExample) |
| AU (1) | AU2016366192B2 (enExample) |
| BR (1) | BR112018011636B1 (enExample) |
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| ES (1) | ES2963058T3 (enExample) |
| IL (1) | IL259838B2 (enExample) |
| MX (1) | MX2018006912A (enExample) |
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| WO (1) | WO2017100367A1 (enExample) |
| ZA (1) | ZA202407197B (enExample) |
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| DK3155024T4 (da) | 2014-06-11 | 2025-07-21 | Massachusetts Inst Technology | Opholdsstrukturer og relaterede fremgangsmåder |
| US20170266112A1 (en) | 2014-06-11 | 2017-09-21 | Massachusetts Institute Of Technology | Residence structures and related methods |
| US10953208B2 (en) | 2015-05-01 | 2021-03-23 | Massachusetts Institute Of Technology | Triggerable shape memory induction devices |
| AU2016342374B2 (en) | 2015-10-23 | 2022-08-04 | Lyndra Therapeutics, Inc. | Gastric residence systems for sustained release of therapeutic agents and methods of use thereof |
| US11992552B2 (en) | 2015-12-08 | 2024-05-28 | Lyndra Therapeutics, Inc. | Geometric configurations for gastric residence systems |
| EP3463313A4 (en) | 2016-05-27 | 2019-12-18 | Lyndra, Inc. | MATERIAL ARCHITECTURE FOR STOMACH DWELLING SYSTEMS |
| AU2017336154B2 (en) | 2016-09-30 | 2023-11-09 | Lyndra Therapeutics, Inc. | Gastric residence systems for sustained delivery of adamantane-class drugs |
| DK3624887T3 (da) | 2017-05-17 | 2025-05-19 | Massachusetts Inst Technology | Vævforankringsartikler |
| US11541015B2 (en) | 2017-05-17 | 2023-01-03 | Massachusetts Institute Of Technology | Self-righting systems, methods, and related components |
| WO2018227147A1 (en) | 2017-06-09 | 2018-12-13 | Lyndra, Inc. | Gastric residence systems with release rate-modulating films |
| JP7288435B2 (ja) * | 2017-09-20 | 2023-06-07 | リンドラ セラピューティクス， インコーポレイティド | 胃内滞留システムのカプセル封入 |
| EP3716850A1 (en) * | 2017-11-28 | 2020-10-07 | Massachusetts Institute of Technology | Gastric resident electronics |
| EP3793667A1 (en) | 2018-05-17 | 2021-03-24 | Massachusetts Institute of Technology | Systems for electrical stimulation |
| US12142158B2 (en) | 2018-12-03 | 2024-11-12 | Lyndra Therapeutics, Inc. | Stomach simulating device |
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- 2016-12-07 US US15/782,021 patent/US11992552B2/en active Active
- 2016-12-07 KR KR1020187019485A patent/KR102796240B1/ko active Active
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| CA3007633A1 (en) | 2017-06-15 |
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| ZA202407197B (en) | 2025-06-25 |
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| US20190262265A1 (en) | 2019-08-29 |
| HK1259225A1 (en) | 2019-11-29 |
| SG11201804384UA (en) | 2018-06-28 |
| BR112018011636A2 (pt) | 2018-11-27 |
| ES2963058T3 (es) | 2024-03-25 |
| AU2016366192A1 (en) | 2018-07-05 |
| EP4302817A3 (en) | 2024-02-21 |
| KR102796240B1 (ko) | 2025-04-16 |
| EP3386488A4 (en) | 2019-08-07 |
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| KR20180090881A (ko) | 2018-08-13 |
| CN120827528A (zh) | 2025-10-24 |
| RU2018124706A3 (enExample) | 2020-06-08 |
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