BR112017025097A2 - método para quantificação espectrométrica de massa de analitos extraídos de um dispositivo de microamostragem - Google Patents

método para quantificação espectrométrica de massa de analitos extraídos de um dispositivo de microamostragem

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Publication number
BR112017025097A2
BR112017025097A2 BR112017025097A BR112017025097A BR112017025097A2 BR 112017025097 A2 BR112017025097 A2 BR 112017025097A2 BR 112017025097 A BR112017025097 A BR 112017025097A BR 112017025097 A BR112017025097 A BR 112017025097A BR 112017025097 A2 BR112017025097 A2 BR 112017025097A2
Authority
BR
Brazil
Prior art keywords
analyte
micro
sampling device
amount
mass spectrometric
Prior art date
Application number
BR112017025097A
Other languages
English (en)
Other versions
BR112017025097B1 (pt
Inventor
WEBER Darren
Tran Diana
ADDISS Julia
EDINBORO Leslie
Goldman Mildred
Clarke Nigel
MISTRY Porus
Goldman Scott
Original Assignee
Quest Diagnostics Invest Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quest Diagnostics Invest Llc filed Critical Quest Diagnostics Invest Llc
Publication of BR112017025097A2 publication Critical patent/BR112017025097A2/pt
Publication of BR112017025097B1 publication Critical patent/BR112017025097B1/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4055—Concentrating samples by solubility techniques
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8822—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/493—Physical analysis of biological material of liquid biological material urine

Abstract

a presente invenção refere-se a métodos espectrométricos de massa para determinação da quantidade de analito em uma amostra coletada por um dispositivo de microamostragem. são providos aqui métodos direcionados à quantificação da quantidade de um analito em uma amostra através da extração de um analito de uma amostra coletada por um dispositivo de microamostragem, purificação da amostra através de cromatografia líquida, ionização do analito para gerar um ou mais íons detectáveis através de espectrometria de massa; e determinação da quantidade do um ou mais íons através de espectrometria de massa. a quantidade de analito na amostra está relacionada à quantidade de analito no paciente.
BR112017025097-7A 2015-05-27 2016-05-27 método para quantificação espectrométrica de massa de analitos extraídos de um dispositivo de microamostragem BR112017025097B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562167164P 2015-05-27 2015-05-27
US62/167,164 2015-05-27
PCT/US2016/034815 WO2016191738A1 (en) 2015-05-27 2016-05-27 Methods for mass spectrometric quantitation of analytes extracted from a microsampling device

Publications (2)

Publication Number Publication Date
BR112017025097A2 true BR112017025097A2 (pt) 2019-04-24
BR112017025097B1 BR112017025097B1 (pt) 2021-05-11

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017025097-7A BR112017025097B1 (pt) 2015-05-27 2016-05-27 método para quantificação espectrométrica de massa de analitos extraídos de um dispositivo de microamostragem

Country Status (8)

Country Link
US (1) US20160349221A1 (pt)
EP (1) EP3304064A4 (pt)
JP (2) JP2018515796A (pt)
CN (1) CN107850568A (pt)
BR (1) BR112017025097B1 (pt)
CA (1) CA2987323A1 (pt)
MX (1) MX2017015229A (pt)
WO (1) WO2016191738A1 (pt)

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Also Published As

Publication number Publication date
BR112017025097B1 (pt) 2021-05-11
MX2017015229A (es) 2018-02-19
EP3304064A1 (en) 2018-04-11
CA2987323A1 (en) 2016-12-01
JP2021119346A (ja) 2021-08-12
EP3304064A4 (en) 2019-03-13
WO2016191738A1 (en) 2016-12-01
US20160349221A1 (en) 2016-12-01
JP2018515796A (ja) 2018-06-14
CN107850568A (zh) 2018-03-27

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/05/2016, OBSERVADAS AS CONDICOES LEGAIS.