MX2017015229A - Metodos para la cuantificacion espectrometrica de masas de analitos extraidos de un dispositivo de micromuestreo. - Google Patents
Metodos para la cuantificacion espectrometrica de masas de analitos extraidos de un dispositivo de micromuestreo.Info
- Publication number
- MX2017015229A MX2017015229A MX2017015229A MX2017015229A MX2017015229A MX 2017015229 A MX2017015229 A MX 2017015229A MX 2017015229 A MX2017015229 A MX 2017015229A MX 2017015229 A MX2017015229 A MX 2017015229A MX 2017015229 A MX2017015229 A MX 2017015229A
- Authority
- MX
- Mexico
- Prior art keywords
- analyte
- methods
- amount
- mass spectrometric
- microsampling device
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4055—Concentrating samples by solubility techniques
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
- G01N2030/8822—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/493—Physical analysis of biological material of liquid biological material urine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Ecology (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
Abstract
Se describen métodos espectrométricos de masas para determinar la cantidad de un analito en una muestra recolectada por un dispositivo de micromuestreo. En el presente documento se proporcionan métodos dirigidos a la cuantificación de la cantidad de un analito en una muestra al extraer un analito de una muestra recolectada por un dispositivo de micromuestreo, purificar la muestra por cromatografía líquida, ionizar el analito para generar uno o más iones detectables por espectrometría de masas, y determinar la cantidad del o los iones por espectrometría de masas. La cantidad del analito en la muestra se relaciona con la cantidad del analito en el paciente.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562167164P | 2015-05-27 | 2015-05-27 | |
PCT/US2016/034815 WO2016191738A1 (en) | 2015-05-27 | 2016-05-27 | Methods for mass spectrometric quantitation of analytes extracted from a microsampling device |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2017015229A true MX2017015229A (es) | 2018-02-19 |
Family
ID=57393339
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017015229A MX2017015229A (es) | 2015-05-27 | 2016-05-27 | Metodos para la cuantificacion espectrometrica de masas de analitos extraidos de un dispositivo de micromuestreo. |
Country Status (8)
Country | Link |
---|---|
US (1) | US20160349221A1 (es) |
EP (1) | EP3304064A4 (es) |
JP (2) | JP2018515796A (es) |
CN (1) | CN107850568A (es) |
BR (1) | BR112017025097B1 (es) |
CA (1) | CA2987323A1 (es) |
MX (1) | MX2017015229A (es) |
WO (1) | WO2016191738A1 (es) |
Families Citing this family (34)
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JP7393206B2 (ja) * | 2016-12-19 | 2023-12-06 | メタボロン,インコーポレイテッド | 腎機能代謝産物の検出及び定量化のための質量分析アッセイ方法 |
TWI786079B (zh) | 2017-01-10 | 2022-12-11 | 美商集聯健康有限公司 | 用於收集及儲存血液的裝置 |
CN107064400B (zh) * | 2017-04-20 | 2018-09-21 | 博厚健康科技股份有限公司 | 同时检测血清中五种类固醇激素的方法 |
CN107576624B (zh) * | 2017-08-31 | 2019-06-25 | 中国人民解放军第三军医大学 | 一种唾液中皮质醇的检测方法 |
US20210086176A1 (en) * | 2017-11-01 | 2021-03-25 | The Board Of Trustees Of The Leland Stanford Junior University | Analyte Detection method |
JP2021512292A (ja) * | 2018-01-23 | 2021-05-13 | ペルキネルマー ヘルス サイエンシーズ, インコーポレイテッド | 残留農薬のmrm遷移を検出するように構成される、トリプル四重極型質量分析計 |
BR112020018817A2 (pt) | 2018-03-16 | 2021-02-09 | Quest Diagnostics Investments Llc | determinação espectrométrica de massa de testosterona em amostras de pacientes multiplexados |
CN108445113B (zh) * | 2018-05-30 | 2022-07-26 | 北京和合医学诊断技术股份有限公司 | 检测血液中氯硝西泮含量的在线固相萃取液相色谱分析方法 |
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CN110187043A (zh) * | 2019-04-25 | 2019-08-30 | 中南民族大学 | 一种同时检测血清中13种甾体激素的方法 |
CA3138346A1 (en) * | 2019-05-31 | 2020-12-03 | Metabolon, Inc. | Mass spectrometry assay methods for detection of metabolites |
CN110389185A (zh) * | 2019-07-25 | 2019-10-29 | 深圳健科医学检验实验室 | 一种唾液中多种类固醇激素的固相萃取方法以及对该类固醇激素的检测方法 |
CN110646544A (zh) * | 2019-10-10 | 2020-01-03 | 山东省农业科学院农业质量标准与检测技术研究所 | 一种快速检测叶菜类蔬菜中农药残留的方法 |
CN112710766A (zh) * | 2019-10-25 | 2021-04-27 | 深圳华大临床检验中心 | 一种检测干血片中五种免疫抑制剂的方法及其试剂盒 |
CN110632235A (zh) * | 2019-11-12 | 2019-12-31 | 北京和合医学诊断技术股份有限公司 | 检测血液中苯妥英钠的方法 |
CN111879883A (zh) * | 2019-11-15 | 2020-11-03 | 厦门市健康医疗大数据中心(厦门市医药研究所) | 一种衍生化反应辅助富集家蚕或其制品中活性成分的检测方法 |
CN112964809A (zh) * | 2019-12-13 | 2021-06-15 | 中国科学院大连化学物理研究所 | 一种检测生物体液多种类固醇激素试剂盒及其使用方法 |
EP4090964A1 (en) * | 2020-01-17 | 2022-11-23 | Waters Technologies Corporation | Methods to increase sensitivity lc/ms analysis |
US11740211B2 (en) | 2020-01-31 | 2023-08-29 | Waters Technologies Corporation | LC/MS adduct mitigation by vapor deposition coated surfaces |
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JP3685119B2 (ja) * | 2001-10-18 | 2005-08-17 | 株式会社日立製作所 | 生体分子回収方法 |
US20110306080A1 (en) * | 2001-11-05 | 2011-12-15 | Quest Diagnostics Investments Incorporated | Determination of lamotrigine by mass spectrometry |
WO2005063962A1 (en) * | 2003-12-24 | 2005-07-14 | Drug Risk Solutions, Inc. | System for comminuting, extracting and detecting analytes in sold biological samples |
EP2001534A4 (en) * | 2006-03-07 | 2013-07-03 | Univ Florida | MEDICATION ADHESION MONITORING SYSTEM |
US8704167B2 (en) * | 2009-04-30 | 2014-04-22 | Purdue Research Foundation | Mass spectrometry analysis of microorganisms in samples |
DE102010003494A1 (de) * | 2010-03-31 | 2011-10-06 | Bayer Schering Pharma Aktiengesellschaft | Parenterales Abgabesystem, das Aromatasehemmer und Gestagene freisetzt, für die Behandlung von Endometriose |
US20120153138A1 (en) * | 2010-12-17 | 2012-06-21 | eLab Consulting Services, Inc. | Methods for detecting substances in biological samples |
EP3091562B1 (en) * | 2010-12-28 | 2019-01-30 | Quest Diagnostics Investments LLC | Quantitation of insulin by mass spectrometry |
JP6357098B2 (ja) * | 2011-06-06 | 2018-07-11 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 試料中の標的分析物を定量化するための組成物、方法およびキット |
JP6203721B2 (ja) * | 2011-08-22 | 2017-09-27 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 抽出サンプルの希釈を伴うマイクロ流体システムにおける乾燥血液スポットサンプルの分析 |
EP3296300B1 (en) * | 2012-03-05 | 2019-08-07 | Xavier University | Boron-based 4-hydroxytamoxifen and endoxifen prodrugs as treatment for breast cancer |
-
2016
- 2016-05-27 US US15/167,866 patent/US20160349221A1/en not_active Abandoned
- 2016-05-27 EP EP16800835.7A patent/EP3304064A4/en not_active Withdrawn
- 2016-05-27 JP JP2018514936A patent/JP2018515796A/ja active Pending
- 2016-05-27 WO PCT/US2016/034815 patent/WO2016191738A1/en active Application Filing
- 2016-05-27 BR BR112017025097-7A patent/BR112017025097B1/pt active IP Right Grant
- 2016-05-27 CA CA2987323A patent/CA2987323A1/en not_active Abandoned
- 2016-05-27 CN CN201680042527.8A patent/CN107850568A/zh active Pending
- 2016-05-27 MX MX2017015229A patent/MX2017015229A/es unknown
-
2021
- 2021-04-08 JP JP2021065745A patent/JP2021119346A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20160349221A1 (en) | 2016-12-01 |
EP3304064A1 (en) | 2018-04-11 |
JP2021119346A (ja) | 2021-08-12 |
BR112017025097B1 (pt) | 2021-05-11 |
CA2987323A1 (en) | 2016-12-01 |
CN107850568A (zh) | 2018-03-27 |
BR112017025097A2 (pt) | 2019-04-24 |
EP3304064A4 (en) | 2019-03-13 |
JP2018515796A (ja) | 2018-06-14 |
WO2016191738A1 (en) | 2016-12-01 |
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