BR112017023935A2 - processo para a preparação de um composto, composto e mistura do composto - Google Patents

processo para a preparação de um composto, composto e mistura do composto

Info

Publication number
BR112017023935A2
BR112017023935A2 BR112017023935-3A BR112017023935A BR112017023935A2 BR 112017023935 A2 BR112017023935 A2 BR 112017023935A2 BR 112017023935 A BR112017023935 A BR 112017023935A BR 112017023935 A2 BR112017023935 A2 BR 112017023935A2
Authority
BR
Brazil
Prior art keywords
compound
preparing
mixing
mixtures
preparation
Prior art date
Application number
BR112017023935-3A
Other languages
English (en)
Other versions
BR112017023935B1 (pt
Inventor
George KLAUBER Eric
Rack Michael
Goetz Roland
Sõrgel Sebastian
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53274420&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112017023935(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Basf Se filed Critical Basf Se
Priority to BR122019027518A priority Critical patent/BR122019027518B8/pt
Publication of BR112017023935A2 publication Critical patent/BR112017023935A2/pt
Publication of BR112017023935B1 publication Critical patent/BR112017023935B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B31/00—Reduction in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B39/00—Halogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B43/00—Formation or introduction of functional groups containing nitrogen
    • C07B43/04—Formation or introduction of functional groups containing nitrogen of amino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/12—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

a presente invenção se refere a um processo para a preparação de um composto de amina de piridazina de fórmula v e aos processos para a preparação de compostos de amina de dicloropiridazina de fórmula iva, ivb, ou suas misturas. além disso, a presente invenção se refere aos compostos inovadores de amina de dicloropiridazina de fórmula iva, ivb, ou suas misturas, em que o grupo de amino é um grupo de etilamino.
BR112017023935-3A 2015-05-11 2016-05-10 processo para a preparação de um composto BR112017023935B1 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122019027518A BR122019027518B8 (pt) 2015-05-11 2016-05-10 processos para a preparação de um composto, composto de amina de dicloropiridazina e mistura do composto de amina de dicloropiridazina

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562159392P 2015-05-11 2015-05-11
US62/159,392 2015-05-11
EP15169166 2015-05-26
EP15169166.4 2015-05-26
PCT/EP2016/060461 WO2016180833A1 (en) 2015-05-11 2016-05-10 Process for preparing 4-amino-pyridazines

Publications (2)

Publication Number Publication Date
BR112017023935A2 true BR112017023935A2 (pt) 2018-07-24
BR112017023935B1 BR112017023935B1 (pt) 2020-07-07

Family

ID=53274420

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017023935-3A BR112017023935B1 (pt) 2015-05-11 2016-05-10 processo para a preparação de um composto

Country Status (17)

Country Link
US (3) US10584102B2 (pt)
EP (2) EP3872073A1 (pt)
JP (1) JP6833718B2 (pt)
KR (3) KR102585412B1 (pt)
CN (1) CN107592859A (pt)
AU (1) AU2016260784B2 (pt)
BR (1) BR112017023935B1 (pt)
CA (2) CA2984703C (pt)
CL (1) CL2017002813A1 (pt)
CO (1) CO2017012403A2 (pt)
ES (1) ES2882543T3 (pt)
IL (1) IL255302B (pt)
MX (2) MX2017014287A (pt)
PE (1) PE20180327A1 (pt)
RU (1) RU2742663C2 (pt)
WO (1) WO2016180833A1 (pt)
ZA (1) ZA201708142B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016016369A1 (en) 2014-07-31 2016-02-04 Basf Se Process for preparing pyrazoles
EP3294720B1 (en) 2015-05-08 2020-12-02 BASF Agro B.V. A process for the preparation of terpinolene epoxide
DK3294700T3 (da) 2015-05-08 2020-04-14 Basf Agro Bv Fremgangsmåde til fremstilling af limonen-4-ol
EP3872073A1 (en) 2015-05-11 2021-09-01 Basf Se Process for preparing 4-amino-pyridazines
WO2017133942A1 (en) 2016-02-02 2017-08-10 Basf Se Catalytic hydrogenation process for preparing pyrazoles
KR20190017926A (ko) 2016-06-15 2019-02-20 바스프 아그로 비.브이. 사치환된 알켄의 에폭시화 방법
ES2833202T3 (es) 2016-06-15 2021-06-14 Basf Agro Bv Procedimiento para la epoxidación de un alqueno tetrasustituido
US10526264B2 (en) 2016-07-07 2020-01-07 Basf Se Oxy-cope rearrangement for the manufacture of insecticidal cyclopentene compounds
WO2018082964A1 (en) 2016-11-04 2018-05-11 Basf Se Process for the production of pyridazinyl-amides in a one-pot synthesis
WO2018083040A1 (en) 2016-11-04 2018-05-11 Basf Se Process for purification of pyrazolpyridazines
US10538493B2 (en) 2016-11-17 2020-01-21 Basf Se Process for the purification of 1-(4-chlorophenyl)pyrazol-3-ol
MX2019009729A (es) 2017-02-14 2019-10-22 Basf Se Formulacion estable de plaguicidas de piridazinpirazolamidas.
JP7005651B2 (ja) 2017-03-20 2022-01-21 ビーエーエスエフ ソシエタス・ヨーロピア ブロモトリクロロメタンを調製する方法
FI3908584T3 (fi) * 2019-01-11 2023-06-19 Basf Se 1-(1,2-dimetyylipropyyli)-N-etyyli-5-metyyli-N-pyridatsin-4-yylipyratsoli-4-karboksamidin kiteisiä muotoja
EP3962269A1 (en) 2019-05-03 2022-03-09 Basf Se Stabilization of suspension concentrates by ethoxylated ricinolein
CA3135706A1 (en) 2019-05-03 2020-11-12 Wen Xu Stabilization of suspension concentrates by highly sulfonated lignosulfonate
WO2020224943A1 (en) 2019-05-03 2020-11-12 Basf Se Stabilization of suspension concentrates by hydrophobic fumed silica

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4A (en) * 1836-08-10 Stock
US4728355A (en) 1985-10-10 1988-03-01 Fmc Corporation Pyridazinylurea plant regulators
RU2069660C1 (ru) * 1994-08-23 1996-11-27 Акционерное общество открытого типа "Научно-исследовательский и проектный институт азотной промышленности и продуктов органического синтеза" Способ получения производных 4-аминопиридина
DE4430757A1 (de) * 1994-08-30 1996-03-07 Boehringer Mannheim Gmbh Neue 4-Aminopyridazine, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
TW406075B (en) * 1994-12-13 2000-09-21 Upjohn Co Alkyl substituted piperidinyl and piperazinyl anti-AIDS compounds
JP4146514B2 (ja) * 1995-07-06 2008-09-10 ノバルティス アクチエンゲゼルシャフト ピロロピリミジン類およびその製造方法
US6258822B1 (en) 1997-08-06 2001-07-10 Abbott Laboratories Urokinase inhibitors
ATE304535T1 (de) 1998-06-05 2005-09-15 Egyt Gyogyszervegyeszeti Gyar Verfahren zu herstellung von 3(2h)pyridazinon-4- substituierte amino-5-chloro derivate
HUP0203375A3 (en) 1999-07-28 2005-03-29 Aventis Pharm Prod Inc Substituted oxoazaheterocyclyl compounds
SI1379520T1 (sl) * 2001-02-23 2006-08-31 Merck & Co Inc N-substituirani nonaril-heterociklicni NMDA/NR2B antagonisti
WO2002100352A2 (en) 2001-06-12 2002-12-19 Merck & Co., Inc. Nr2b receptor antagonists for the treatment or prevention of migraines
SI1809622T1 (sl) * 2004-09-22 2010-11-30 Janssen Pharmaceutica Nv Inhibitorji interakcije med MDM in P
JP2007326784A (ja) 2006-06-06 2007-12-20 Sagami Chem Res Center １−置換−５−フルオロアルキルピラゾール−４−カルボン酸エステルの製造方法
US20110189167A1 (en) 2007-04-20 2011-08-04 Flynn Daniel L Methods and Compositions for the Treatment of Myeloproliferative Diseases and other Proliferative Diseases
PL2197280T3 (pl) 2007-08-27 2013-11-29 Basf Se Związki pirazolowe do zwalczania szkodników będących bezkręgowcami
WO2009068652A1 (en) 2007-11-30 2009-06-04 Smithkline Beecham Corporation 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines as soluble guanylate cyclase activators
MY158927A (en) 2008-06-12 2016-11-30 Janssen Pharmaceutica Nv Diamino-pyridine, pyrimidine, and pyridazine modulators of the histamine h4 receptor
US8853125B2 (en) 2008-09-24 2014-10-07 Basf Se Pyrazole compounds for controlling invertebrate pests
US8729083B2 (en) 2008-09-24 2014-05-20 Basf Se Pyrazole compounds for controlling invertebrate pests
US20100113465A1 (en) 2008-10-30 2010-05-06 Pfizer Inc. 7-azaspiro[3.5]nonane-7-carboxamide compounds
EP2236505A1 (de) 2009-04-03 2010-10-06 Bayer CropScience AG Acylierte Aminopyridine und - pyridazine als Insektizide
AR076984A1 (es) 2009-06-08 2011-07-20 Merck Serono Sa Derivados de pirazol oxadiazol
MX2012003778A (es) * 2009-09-29 2012-06-01 Glaxo Group Ltd Compuestos novedosos.
WO2011124524A1 (de) 2010-04-08 2011-10-13 Boehringer Ingelheim International Gmbh Arzneimittelkombinationen enthaltend pde4-inhibitoren und ep4-rezeptor-antagonisten
EP2468736A1 (en) * 2010-12-23 2012-06-27 LEK Pharmaceuticals d.d. Synthesis of intermediates for preparing anacetrapib and derivates thereof
WO2012098387A1 (en) 2011-01-18 2012-07-26 Centro Nacional De Investigaciones Oncológicas (Cnio) 6, 7-ring-fused triazolo [4, 3 - b] pyridazine derivatives as pim inhibitors
ES2864590T3 (es) 2011-04-12 2021-10-14 Thermedical Inc Dispositivos para controlar el tratamiento ablativo
EA024737B1 (ru) 2011-04-21 2016-10-31 Басф Се Новые пестицидные соединения пиразола
WO2013004984A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncologicas (Cnio) Tricyclic compounds for use as kinase inhibitors
WO2013142269A1 (en) 2012-03-19 2013-09-26 Envivo Pharmaceuticals, Inc. Imidazotriazinone compounds
WO2013156318A1 (en) * 2012-04-16 2013-10-24 Basf Se Substituted pesticidal pyrazole compounds
JO3407B1 (ar) 2012-05-31 2019-10-20 Eisai R&D Man Co Ltd مركبات رباعي هيدرو بيرازولو بيريميدين
EP2671873A1 (en) 2012-06-06 2013-12-11 Solvay Sa Method for the cyclization of hydrazinoacrylic acid derivatives
BR122019015130B1 (pt) 2012-06-20 2020-04-07 Basf Se mistura pesticida, composição, composição agrícola, métodos para o combate ou controle das pragas de invertebrados, para a proteção dos vegetais em crescimento ou dos materias de propagação vegetal, para a proteção de material de propagação vegetal, uso de uma mistura pesticida e métodos para o combate dos fungos fitopatogênicos nocivos e para proteger vegetais de fungos fitopatogênicos nocivos
WO2014063929A1 (en) * 2012-10-23 2014-05-01 Basf Se Substituted pesticidal pyrazole compounds
US9604961B2 (en) 2012-12-06 2017-03-28 Celgene Quanticel Research, Inc. Histone demethylase inhibitors
UA112028C2 (uk) 2012-12-14 2016-07-11 Пфайзер Лімітед Похідні імідазопіридазину як модулятори гамка-рецептора
WO2015055497A1 (en) * 2013-10-16 2015-04-23 Basf Se Substituted pesticidal pyrazole compounds
CR20160397A (es) 2014-01-31 2016-10-27 Basf Se Pirazoles para el control de plagas de invertebrados
WO2015162133A1 (en) 2014-04-22 2015-10-29 Basf Se C3-c4-cycloalkenyl-comprising pyrazoles for controlling invertebrate pests
WO2015169734A1 (en) 2014-05-05 2015-11-12 Basf Se Pyrazoles for controlling invertebrate pests
WO2015189080A1 (en) 2014-06-12 2015-12-17 Basf Se Pesticidally active mixtures
WO2016016369A1 (en) 2014-07-31 2016-02-04 Basf Se Process for preparing pyrazoles
EP3255990B1 (en) 2015-02-11 2020-06-24 Basf Se Pesticidal mixture comprising a pyrazole compound, an insecticide and a fungicide
WO2016128240A1 (en) 2015-02-11 2016-08-18 Basf Se Pesticidal mixture comprising a pyrazole compound and two fungicides
WO2016128239A1 (en) 2015-02-11 2016-08-18 Basf Se Pesticidal mixture comprising a pyrazole compound and a biopesticide
EP3872073A1 (en) * 2015-05-11 2021-09-01 Basf Se Process for preparing 4-amino-pyridazines
WO2017133942A1 (en) 2016-02-02 2017-08-10 Basf Se Catalytic hydrogenation process for preparing pyrazoles

Also Published As

Publication number Publication date
PE20180327A1 (es) 2018-02-13
US20210276959A1 (en) 2021-09-09
BR112017023935B1 (pt) 2020-07-07
EP3294725B1 (en) 2021-05-05
CN107592859A (zh) 2018-01-16
CA2984703C (en) 2024-04-02
CA3187499A1 (en) 2016-11-17
CL2017002813A1 (es) 2018-05-04
IL255302A0 (en) 2017-12-31
JP6833718B2 (ja) 2021-02-24
RU2742663C2 (ru) 2021-02-09
CO2017012403A2 (es) 2018-04-19
KR20180003610A (ko) 2018-01-09
EP3294725A1 (en) 2018-03-21
MX2017014287A (es) 2018-03-07
RU2017142621A (ru) 2019-06-11
US10584102B2 (en) 2020-03-10
ZA201708142B (en) 2019-05-29
CA2984703A1 (en) 2016-11-17
US20200140396A1 (en) 2020-05-07
US20180141917A1 (en) 2018-05-24
AU2016260784A1 (en) 2017-11-30
KR20240033160A (ko) 2024-03-12
WO2016180833A1 (en) 2016-11-17
IL255302B (en) 2020-05-31
JP2018515496A (ja) 2018-06-14
RU2017142621A3 (pt) 2019-08-08
MX2021015546A (es) 2022-02-23
AU2016260784B2 (en) 2020-03-12
US11046656B2 (en) 2021-06-29
EP3872073A1 (en) 2021-09-01
ES2882543T3 (es) 2021-12-02
KR20230145498A (ko) 2023-10-17
KR102585412B1 (ko) 2023-10-05

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Legal Events

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B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 10/05/2016, OBSERVADAS AS CONDICOES LEGAIS.