CL2017002813A1 - Proceso para preparar 4-amino-piridazinas - Google Patents
Proceso para preparar 4-amino-piridazinasInfo
- Publication number
- CL2017002813A1 CL2017002813A1 CL2017002813A CL2017002813A CL2017002813A1 CL 2017002813 A1 CL2017002813 A1 CL 2017002813A1 CL 2017002813 A CL2017002813 A CL 2017002813A CL 2017002813 A CL2017002813 A CL 2017002813A CL 2017002813 A1 CL2017002813 A1 CL 2017002813A1
- Authority
- CL
- Chile
- Prior art keywords
- prepare
- formula
- amino
- pyridazines
- dicloropiridazinamine
- Prior art date
Links
- LUCGBEPEAUHERV-UHFFFAOYSA-N pyridazin-4-amine Chemical class NC1=CC=NN=C1 LUCGBEPEAUHERV-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- -1 AMINO GROUP Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B31/00—Reduction in general
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B39/00—Halogenation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B43/00—Formation or introduction of functional groups containing nitrogen
- C07B43/04—Formation or introduction of functional groups containing nitrogen of amino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/12—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
<p>LA PRESENTE INVENCIÓN SE REFIERE A UN PROCESO PARA PREPARAR UN COMPUESTO DE PIRIDAZINAMINA DE FÓRMULA V, Y A PROCESOS PARA PREPARAR COMPUESTOS DE DICLOROPIRIDAZINAMINA DE FÓRMULA IVA, LVB, O MEZCLAS DE LAS MISMAS. ADEMÁS, LA PRESENTE INVENCIÓN SE REFIERE A LOS NUEVOS COMPUESTOS DE DICLOROPIRIDAZINAMINA DE FÓRMULA IVA, LVB, O MEZCLAS CE LAS MISMAS, EN DONDE EL GRUPO AMINO ES UN GRUPO ETILAMINO.</p>
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562159392P | 2015-05-11 | 2015-05-11 | |
EP15169166 | 2015-05-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2017002813A1 true CL2017002813A1 (es) | 2018-05-04 |
Family
ID=53274420
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2017002813A CL2017002813A1 (es) | 2015-05-11 | 2017-11-07 | Proceso para preparar 4-amino-piridazinas |
Country Status (17)
Country | Link |
---|---|
US (3) | US10584102B2 (es) |
EP (2) | EP3872073A1 (es) |
JP (1) | JP6833718B2 (es) |
KR (3) | KR20240033160A (es) |
CN (1) | CN107592859A (es) |
AU (1) | AU2016260784B2 (es) |
BR (1) | BR112017023935B1 (es) |
CA (2) | CA2984703C (es) |
CL (1) | CL2017002813A1 (es) |
CO (1) | CO2017012403A2 (es) |
ES (1) | ES2882543T3 (es) |
IL (1) | IL255302B (es) |
MX (2) | MX2017014287A (es) |
PE (1) | PE20180327A1 (es) |
RU (1) | RU2742663C2 (es) |
WO (1) | WO2016180833A1 (es) |
ZA (1) | ZA201708142B (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK3174858T3 (da) | 2014-07-31 | 2019-07-15 | Basf Se | Fremgangsmåde til fremstilling af pyrazoler |
DK3294720T3 (da) | 2015-05-08 | 2021-02-15 | Basf Agro Bv | Fremgangsmåde til fremstilling af terpinolenepoxid |
DK3294700T3 (da) | 2015-05-08 | 2020-04-14 | Basf Agro Bv | Fremgangsmåde til fremstilling af limonen-4-ol |
JP6833718B2 (ja) * | 2015-05-11 | 2021-02-24 | ビーエイエスエフ・ソシエタス・エウロパエアBasf Se | 4−アミノ−ピリダジンを製造するための方法 |
PL3411360T3 (pl) | 2016-02-02 | 2020-08-24 | Basf Se | Sposób katalitycznego uwodorniania dla wytwarzania pirazoli |
EP3472138B1 (en) | 2016-06-15 | 2020-08-26 | BASF Agro B.V. | Process for the epoxidation of a tetrasubstituted alkene |
KR20190017926A (ko) | 2016-06-15 | 2019-02-20 | 바스프 아그로 비.브이. | 사치환된 알켄의 에폭시화 방법 |
WO2018007175A1 (en) | 2016-07-07 | 2018-01-11 | Basf Se | Oxy-cope rearrangement for the manufacture of insecticidal cyclopentene compounds |
ES2858699T3 (es) | 2016-11-04 | 2021-09-30 | Basf Se | Procedimiento para la purificación de pirazolpiridazinas |
WO2018082964A1 (en) | 2016-11-04 | 2018-05-11 | Basf Se | Process for the production of pyridazinyl-amides in a one-pot synthesis |
MX2019005785A (es) | 2016-11-17 | 2019-08-22 | Basf Se | Proceso para la purificacion de 1-(4-clorofenil)pirazol-3-ol. |
HUE059735T2 (hu) | 2017-02-14 | 2022-12-28 | Basf Se | Stabil, peszticid hatású piridazinpirazolamid-készítmény |
CN110431126B (zh) | 2017-03-20 | 2022-12-02 | 巴斯夫欧洲公司 | 制备一溴三氯甲烷的方法 |
PL3908584T3 (pl) * | 2019-01-11 | 2023-08-14 | Basf Se | Krystaliczne postacie 1-(1,2-dimetylopropylo)-n-etylo-5-metylo-n-pirydazyny-4-ylopirazolo-4-karboksyamidu |
US20220183278A1 (en) | 2019-05-03 | 2022-06-16 | Basf Se | Stabilization of suspension concentrates by hydrophobic fumed silica |
WO2020224942A1 (en) | 2019-05-03 | 2020-11-12 | Basf Se | Stabilization of suspension concentrates by ethoxylated ricinolein |
CN113795148A (zh) | 2019-05-03 | 2021-12-14 | 巴斯夫欧洲公司 | 通过高度磺化木素磺酸盐稳定悬浮浓缩物 |
Family Cites Families (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4A (en) * | 1836-08-10 | Stock | ||
US4728355A (en) * | 1985-10-10 | 1988-03-01 | Fmc Corporation | Pyridazinylurea plant regulators |
RU2069660C1 (ru) * | 1994-08-23 | 1996-11-27 | Акционерное общество открытого типа "Научно-исследовательский и проектный институт азотной промышленности и продуктов органического синтеза" | Способ получения производных 4-аминопиридина |
DE4430757A1 (de) * | 1994-08-30 | 1996-03-07 | Boehringer Mannheim Gmbh | Neue 4-Aminopyridazine, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel |
TW406075B (en) * | 1994-12-13 | 2000-09-21 | Upjohn Co | Alkyl substituted piperidinyl and piperazinyl anti-AIDS compounds |
KR100437582B1 (ko) * | 1995-07-06 | 2004-12-17 | 노파르티스 아게 | 피롤로피리미딘및그들의제조방법 |
US6258822B1 (en) | 1997-08-06 | 2001-07-10 | Abbott Laboratories | Urokinase inhibitors |
CN1205190C (zh) | 1998-06-05 | 2005-06-08 | 埃吉斯药物工厂 | 制备3(2h)-哒嗪酮-4-取代氨基-5-氯-衍生物的方法 |
CN1420882A (zh) | 1999-07-28 | 2003-05-28 | 阿温蒂斯药物公司 | 取代的氧代氮杂杂环基化合物 |
EP1379520B2 (en) * | 2001-02-23 | 2014-04-09 | Merck Sharp & Dohme Corp. | N-substituted nonaryl-heterocyclic nmda/nr2b antagonists |
JP2004537526A (ja) | 2001-06-12 | 2004-12-16 | メルク エンド カムパニー インコーポレーテッド | 片頭痛の治療又は予防用nr2b受容体拮抗薬 |
NZ553646A (en) * | 2004-09-22 | 2010-07-30 | Janssen Pharmaceutica Nv | Inhibitors of the interaction between MDM2 and p53 |
JP2007326784A (ja) | 2006-06-06 | 2007-12-20 | Sagami Chem Res Center | 1−置換−5−フルオロアルキルピラゾール−4−カルボン酸エステルの製造方法 |
US20110189167A1 (en) | 2007-04-20 | 2011-08-04 | Flynn Daniel L | Methods and Compositions for the Treatment of Myeloproliferative Diseases and other Proliferative Diseases |
EP2197280B1 (en) | 2007-08-27 | 2013-06-19 | Basf Se | Pyrazole compounds for controlling invertebrate pests |
WO2009068652A1 (en) | 2007-11-30 | 2009-06-04 | Smithkline Beecham Corporation | 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines as soluble guanylate cyclase activators |
NZ589532A (en) | 2008-06-12 | 2012-02-24 | Janssen Pharmaceutica Nv | Diamino-pyridine, pyrimidine, and pyridazine modulators of the histamine H4 receptor |
EP2346335B1 (en) | 2008-09-24 | 2018-11-14 | Basf Se | Pyrazole compounds for controlling invertebrate pests |
TWI607996B (zh) | 2008-09-24 | 2017-12-11 | 巴地斯顏料化工廠 | 控制無脊椎害蟲之吡唑化合物 |
US20100113465A1 (en) | 2008-10-30 | 2010-05-06 | Pfizer Inc. | 7-azaspiro[3.5]nonane-7-carboxamide compounds |
EP2236505A1 (de) * | 2009-04-03 | 2010-10-06 | Bayer CropScience AG | Acylierte Aminopyridine und - pyridazine als Insektizide |
AR076984A1 (es) | 2009-06-08 | 2011-07-20 | Merck Serono Sa | Derivados de pirazol oxadiazol |
EA021437B1 (ru) * | 2009-09-29 | 2015-06-30 | Глэксо Груп Лимитед | Соединения, ингибирующие lrrk2 киназную активность |
EP2555773A1 (de) | 2010-04-08 | 2013-02-13 | Boehringer Ingelheim International GmbH | Arzneimittelkombinationen enthaltend pde4-inhibitoren und ep4-rezeptor-antagonisten |
EP2468736A1 (en) * | 2010-12-23 | 2012-06-27 | LEK Pharmaceuticals d.d. | Synthesis of intermediates for preparing anacetrapib and derivates thereof |
WO2012098387A1 (en) | 2011-01-18 | 2012-07-26 | Centro Nacional De Investigaciones Oncológicas (Cnio) | 6, 7-ring-fused triazolo [4, 3 - b] pyridazine derivatives as pim inhibitors |
WO2012142291A1 (en) | 2011-04-12 | 2012-10-18 | Thermedical, Inc. | Devices and methods for shaping therapy in fluid enhanced ablation |
HUE029354T2 (en) | 2011-04-21 | 2017-02-28 | Basf Se | New, pesticidal pyrazole compounds |
WO2013004984A1 (en) | 2011-07-07 | 2013-01-10 | Centro Nacional De Investigaciones Oncologicas (Cnio) | Tricyclic compounds for use as kinase inhibitors |
WO2013142269A1 (en) | 2012-03-19 | 2013-09-26 | Envivo Pharmaceuticals, Inc. | Imidazotriazinone compounds |
WO2013156318A1 (en) * | 2012-04-16 | 2013-10-24 | Basf Se | Substituted pesticidal pyrazole compounds |
JO3407B1 (ar) | 2012-05-31 | 2019-10-20 | Eisai R&D Man Co Ltd | مركبات رباعي هيدرو بيرازولو بيريميدين |
EP2671873A1 (en) | 2012-06-06 | 2013-12-11 | Solvay Sa | Method for the cyclization of hydrazinoacrylic acid derivatives |
BR122019015125B1 (pt) | 2012-06-20 | 2020-04-07 | Basf Se | mistura pesticida, composição, composição agrícola, métodos para o combate ou controle das pragas de invertebrados, para a proteção dos vegetais em crescimento ou dos materias de propagação vegetal, para a proteção de material de propagação vegetal, uso de uma mistura pesticida e métodos para o combate dos fungos fitopatogênicos nocivos e para proteger vegetais de fungos fitopatogênicos nocivos |
WO2014063929A1 (en) * | 2012-10-23 | 2014-05-01 | Basf Se | Substituted pesticidal pyrazole compounds |
CA2894399A1 (en) | 2012-12-06 | 2014-06-12 | Quanticel Pharmaceuticals, Inc. | Histone demethylase inhibitors |
UA112028C2 (uk) | 2012-12-14 | 2016-07-11 | Пфайзер Лімітед | Похідні імідазопіридазину як модулятори гамка-рецептора |
WO2015055497A1 (en) * | 2013-10-16 | 2015-04-23 | Basf Se | Substituted pesticidal pyrazole compounds |
EP3099676B1 (en) | 2014-01-31 | 2018-10-24 | Basf Se | Pyrazoles for controlling invertebrate pests |
WO2015162133A1 (en) | 2014-04-22 | 2015-10-29 | Basf Se | C3-c4-cycloalkenyl-comprising pyrazoles for controlling invertebrate pests |
WO2015169734A1 (en) | 2014-05-05 | 2015-11-12 | Basf Se | Pyrazoles for controlling invertebrate pests |
WO2015189080A1 (en) | 2014-06-12 | 2015-12-17 | Basf Se | Pesticidally active mixtures |
DK3174858T3 (da) | 2014-07-31 | 2019-07-15 | Basf Se | Fremgangsmåde til fremstilling af pyrazoler |
CR20170413A (es) | 2015-02-11 | 2018-02-06 | Basf Se | Mezcla plaguicida que comprende un compuesto pirazol, un insecticida y un fungicida |
WO2016128240A1 (en) | 2015-02-11 | 2016-08-18 | Basf Se | Pesticidal mixture comprising a pyrazole compound and two fungicides |
WO2016128239A1 (en) | 2015-02-11 | 2016-08-18 | Basf Se | Pesticidal mixture comprising a pyrazole compound and a biopesticide |
JP6833718B2 (ja) | 2015-05-11 | 2021-02-24 | ビーエイエスエフ・ソシエタス・エウロパエアBasf Se | 4−アミノ−ピリダジンを製造するための方法 |
PL3411360T3 (pl) | 2016-02-02 | 2020-08-24 | Basf Se | Sposób katalitycznego uwodorniania dla wytwarzania pirazoli |
-
2016
- 2016-05-10 JP JP2017557929A patent/JP6833718B2/ja active Active
- 2016-05-10 WO PCT/EP2016/060461 patent/WO2016180833A1/en active Application Filing
- 2016-05-10 CA CA2984703A patent/CA2984703C/en active Active
- 2016-05-10 KR KR1020247006943A patent/KR20240033160A/ko not_active Application Discontinuation
- 2016-05-10 KR KR1020177035243A patent/KR102585412B1/ko active IP Right Grant
- 2016-05-10 RU RU2017142621A patent/RU2742663C2/ru active
- 2016-05-10 KR KR1020237033245A patent/KR20230145498A/ko not_active Application Discontinuation
- 2016-05-10 PE PE2017002379A patent/PE20180327A1/es not_active Application Discontinuation
- 2016-05-10 ES ES16724331T patent/ES2882543T3/es active Active
- 2016-05-10 US US15/572,303 patent/US10584102B2/en active Active
- 2016-05-10 AU AU2016260784A patent/AU2016260784B2/en active Active
- 2016-05-10 EP EP21163074.4A patent/EP3872073A1/en active Pending
- 2016-05-10 CN CN201680026456.2A patent/CN107592859A/zh active Pending
- 2016-05-10 CA CA3187499A patent/CA3187499A1/en active Pending
- 2016-05-10 BR BR112017023935-3A patent/BR112017023935B1/pt active IP Right Grant
- 2016-05-10 MX MX2017014287A patent/MX2017014287A/es unknown
- 2016-05-10 EP EP16724331.0A patent/EP3294725B1/en active Active
-
2017
- 2017-10-29 IL IL255302A patent/IL255302B/en active IP Right Grant
- 2017-11-07 CL CL2017002813A patent/CL2017002813A1/es unknown
- 2017-11-07 MX MX2021015546A patent/MX2021015546A/es unknown
- 2017-11-30 ZA ZA2017/08142A patent/ZA201708142B/en unknown
- 2017-11-30 CO CONC2017/0012403A patent/CO2017012403A2/es unknown
-
2019
- 2019-12-31 US US16/731,289 patent/US11046656B2/en active Active
-
2021
- 2021-05-18 US US17/323,337 patent/US20210276959A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CL2017002813A1 (es) | Proceso para preparar 4-amino-piridazinas | |
EA201890749A1 (ru) | ИНГИБИТОРЫ АЦЕТИЛ-КоА-КАРБОКСИЛАЗЫ (ACC) И ИХ ПРИМЕНЕНИЕ | |
CO2018005381A2 (es) | Inhibidores éster de acc y usos de los mismos | |
EA201891910A1 (ru) | Гетероарильные ингибиторы pad4 | |
EA201792535A1 (ru) | Гетероциклические амиды в качестве ингибиторов киназ | |
EA201792354A1 (ru) | Композиции обетихолевой кислоты и способы применения | |
EA201790722A1 (ru) | КОМПОЗИЦИЯ С НИЗКИМ pH, СОДЕРЖАЩАЯ КОНКРЕТНЫЕ КОНСЕРВАЦИОННЫЕ СИСТЕМЫ | |
EA201890373A1 (ru) | Пиридиновые соединения, пригодные для борьбы с фитопатогенными грибами | |
GT201500334A (es) | Compuestos de 3,4- dihidroisoquinolin-2-(1h)-ilo | |
EA201692193A1 (ru) | Способы получения ингибитора jak1 и его новых форм | |
EA201691794A1 (ru) | Конденсированные [1,4]диазепиновые соединения в качестве ингибиторов продукции аутотаксина (atx) и лизофосфатидиловой кислоты (lpa) | |
EA201891438A1 (ru) | Кислотно-аддитивные соли производных пиперазина | |
EA201691134A1 (ru) | Новые ингибиторы глутаминазы | |
CO2017011553A2 (es) | Sal de (s)-csa de s-ketamina, sal de (r)-csa de s-ketamina y procesos para la preparación de s-ketamina | |
EA201691799A1 (ru) | Бициклические соединения в качестве ингибиторов продукции аутотаксина (atx) и лизофосфатидиловой кислоты (lpa) | |
EA201890052A1 (ru) | Регуляторы nrf2 | |
UY36419A (es) | Composiciones farmacéuticas que contienen anticuerpos anti-cd38 para el tratamiento de la leucemia mieloide aguda | |
EA201890752A1 (ru) | Способ получения противогрибковых соединений | |
EA201891251A1 (ru) | Бициклические ингибиторы pad4 | |
EA201691272A1 (ru) | Тетрагидропиридопиразины в качестве модуляторов gpr6 | |
EA201591889A1 (ru) | 6-(5-гидрокси-1h-пиразол-1-ил)никотинамидные ингибиторы phd | |
EA201891347A1 (ru) | Аза-бензимидазольные ингибиторы pad4 | |
EP3504185A4 (en) | NEW SUBSTITUTED N'-HYDROXYCARBAMIMIDOYL-1,2,5-OXADIAZOLE COMPOUNDS AS INHIBITORS OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) | |
EA201790570A1 (ru) | Модуляторы р2х7 | |
EA201791992A1 (ru) | Ингибиторы грелин-o-ацилтрансферазы |