BR112017002629A2 - decoys de oligonucleotídeo para o tratamento de dor - Google Patents

decoys de oligonucleotídeo para o tratamento de dor

Info

Publication number
BR112017002629A2
BR112017002629A2 BR112017002629-5A BR112017002629A BR112017002629A2 BR 112017002629 A2 BR112017002629 A2 BR 112017002629A2 BR 112017002629 A BR112017002629 A BR 112017002629A BR 112017002629 A2 BR112017002629 A2 BR 112017002629A2
Authority
BR
Brazil
Prior art keywords
oligonucleotide decoys
pain treatment
decoys
double
nucleic acids
Prior art date
Application number
BR112017002629-5A
Other languages
English (en)
Portuguese (pt)
Inventor
Mamet Julien
Orr Rick
Manning Don
Harris Scott
Martin William
Original Assignee
Adynxx, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adynxx, Inc. filed Critical Adynxx, Inc.
Publication of BR112017002629A2 publication Critical patent/BR112017002629A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/13—Decoys

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR112017002629-5A 2014-08-15 2015-08-14 decoys de oligonucleotídeo para o tratamento de dor BR112017002629A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462037996P 2014-08-15 2014-08-15
US62/037,996 2014-08-15
PCT/US2015/045268 WO2016025829A1 (en) 2014-08-15 2015-08-14 Oligonucleotide decoys for the treatment of pain

Publications (1)

Publication Number Publication Date
BR112017002629A2 true BR112017002629A2 (pt) 2018-02-20

Family

ID=55304669

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017002629-5A BR112017002629A2 (pt) 2014-08-15 2015-08-14 decoys de oligonucleotídeo para o tratamento de dor

Country Status (11)

Country Link
US (2) US10287583B2 (enExample)
EP (2) EP3626822A1 (enExample)
JP (2) JP6705807B2 (enExample)
CN (1) CN106661578B (enExample)
AU (1) AU2015301491A1 (enExample)
BR (1) BR112017002629A2 (enExample)
CA (1) CA2957250A1 (enExample)
ES (1) ES2750689T3 (enExample)
PT (1) PT3180434T (enExample)
RU (1) RU2017108238A (enExample)
WO (1) WO2016025829A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3199635B1 (en) 2007-05-11 2019-02-06 Adynxx, Inc. Gene expression and pain
CA2872901A1 (en) 2012-05-10 2013-11-14 Adynxx, Inc. Formulations for the delivery of active ingredients
CA2957250A1 (en) 2014-08-15 2016-02-18 Adynxx, Inc. Oligonucleotide decoys for the treatment of pain
FR3029450B1 (fr) * 2014-12-03 2017-11-03 Pole De Plasturgie De Lest Dispositif de moulage pour la fabrication de pieces en materiau composite a partir de resine polymere liquide par injection haute pression.
CN113453695A (zh) * 2018-12-24 2021-09-28 加州大学评议会 用嵌合体诱饵治疗脊柱病症
CN116096382A (zh) * 2020-08-13 2023-05-09 内华达研究与创新公司 用于治疗糖尿病和肥胖症的KLF11 siRNA
WO2023070072A1 (en) 2021-10-21 2023-04-27 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Retroelement-generated transcription factor decoys

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Also Published As

Publication number Publication date
US20170247694A1 (en) 2017-08-31
CA2957250A1 (en) 2016-02-18
JP2020141688A (ja) 2020-09-10
US10287583B2 (en) 2019-05-14
EP3180434A1 (en) 2017-06-21
EP3180434A4 (en) 2018-04-04
EP3180434B1 (en) 2019-07-17
EP3626822A1 (en) 2020-03-25
WO2016025829A1 (en) 2016-02-18
ES2750689T3 (es) 2020-03-26
CN106661578B (zh) 2020-08-04
JP6705807B2 (ja) 2020-06-03
PT3180434T (pt) 2019-10-29
RU2017108238A (ru) 2018-09-17
US10683502B2 (en) 2020-06-16
RU2017108238A3 (enExample) 2019-09-18
CN106661578A (zh) 2017-05-10
AU2015301491A1 (en) 2017-02-02
US20190276825A1 (en) 2019-09-12
JP2017529834A (ja) 2017-10-12

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B350 Update of information on the portal [chapter 15.35 patent gazette]