ES2750689T3 - Señuelos oligonucleotídicos para el tratamiento del dolor - Google Patents
Señuelos oligonucleotídicos para el tratamiento del dolor Download PDFInfo
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- ES2750689T3 ES2750689T3 ES15832083T ES15832083T ES2750689T3 ES 2750689 T3 ES2750689 T3 ES 2750689T3 ES 15832083 T ES15832083 T ES 15832083T ES 15832083 T ES15832083 T ES 15832083T ES 2750689 T3 ES2750689 T3 ES 2750689T3
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/13—Decoys
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
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- Plant Pathology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462037996P | 2014-08-15 | 2014-08-15 | |
| PCT/US2015/045268 WO2016025829A1 (en) | 2014-08-15 | 2015-08-14 | Oligonucleotide decoys for the treatment of pain |
Publications (1)
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|---|---|
| ES2750689T3 true ES2750689T3 (es) | 2020-03-26 |
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| ES15832083T Active ES2750689T3 (es) | 2014-08-15 | 2015-08-14 | Señuelos oligonucleotídicos para el tratamiento del dolor |
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| US (2) | US10287583B2 (enExample) |
| EP (2) | EP3626822A1 (enExample) |
| JP (2) | JP6705807B2 (enExample) |
| CN (1) | CN106661578B (enExample) |
| AU (1) | AU2015301491A1 (enExample) |
| BR (1) | BR112017002629A2 (enExample) |
| CA (1) | CA2957250A1 (enExample) |
| ES (1) | ES2750689T3 (enExample) |
| PT (1) | PT3180434T (enExample) |
| RU (1) | RU2017108238A (enExample) |
| WO (1) | WO2016025829A1 (enExample) |
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| EP3199635B1 (en) | 2007-05-11 | 2019-02-06 | Adynxx, Inc. | Gene expression and pain |
| CA2872901A1 (en) | 2012-05-10 | 2013-11-14 | Adynxx, Inc. | Formulations for the delivery of active ingredients |
| CA2957250A1 (en) | 2014-08-15 | 2016-02-18 | Adynxx, Inc. | Oligonucleotide decoys for the treatment of pain |
| FR3029450B1 (fr) * | 2014-12-03 | 2017-11-03 | Pole De Plasturgie De Lest | Dispositif de moulage pour la fabrication de pieces en materiau composite a partir de resine polymere liquide par injection haute pression. |
| CN113453695A (zh) * | 2018-12-24 | 2021-09-28 | 加州大学评议会 | 用嵌合体诱饵治疗脊柱病症 |
| CN116096382A (zh) * | 2020-08-13 | 2023-05-09 | 内华达研究与创新公司 | 用于治疗糖尿病和肥胖症的KLF11 siRNA |
| WO2023070072A1 (en) | 2021-10-21 | 2023-04-27 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone | Retroelement-generated transcription factor decoys |
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| US6410516B1 (en) | 1986-01-09 | 2002-06-25 | President & Fellows Of Harvard College | Nuclear factors associated with transcriptional regulation |
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| DE3815221C2 (de) | 1988-05-04 | 1995-06-29 | Gradinger F Hermes Pharma | Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen |
| KR100225087B1 (ko) | 1990-03-23 | 1999-10-15 | 한스 발터라벤 | 피타아제의 식물내 발현 |
| US5272056A (en) | 1991-01-03 | 1993-12-21 | The Research Foundation Of State University Of New York | Modification of DNA and oligonucleotides using metal complexes of polyaza ligands |
| WO1992018522A1 (en) | 1991-04-18 | 1992-10-29 | The Salk Institute For Biological Studies | Oligodeoxynucleotides and oligonucleotides useful as decoys for proteins which selectively bind to defined dna sequences |
| FR2675803B1 (fr) | 1991-04-25 | 1996-09-06 | Genset Sa | Oligonucleotides fermes, antisens et sens et leurs applications. |
| JPH07501204A (ja) | 1991-06-28 | 1995-02-09 | マサチューセッツ インスティテュート オブ テクノロジー | 局所的オリゴヌクレオチド療法 |
| CA2168245A1 (en) | 1993-07-29 | 1995-02-09 | C. Anthony Hunt | Polynucleotide decoys that inhibit mhc-ii expression and uses thereof |
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| PT824918E (pt) | 1995-05-12 | 2007-06-22 | Anges Mg Inc | Tratamento e prevenção para doenças causadas pelo nf-kb |
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-
2015
- 2015-08-14 CA CA2957250A patent/CA2957250A1/en not_active Abandoned
- 2015-08-14 RU RU2017108238A patent/RU2017108238A/ru not_active Application Discontinuation
- 2015-08-14 AU AU2015301491A patent/AU2015301491A1/en not_active Abandoned
- 2015-08-14 EP EP19186119.4A patent/EP3626822A1/en not_active Withdrawn
- 2015-08-14 WO PCT/US2015/045268 patent/WO2016025829A1/en not_active Ceased
- 2015-08-14 JP JP2017508487A patent/JP6705807B2/ja not_active Expired - Fee Related
- 2015-08-14 PT PT158320838T patent/PT3180434T/pt unknown
- 2015-08-14 BR BR112017002629-5A patent/BR112017002629A2/pt not_active Application Discontinuation
- 2015-08-14 US US15/504,191 patent/US10287583B2/en not_active Expired - Fee Related
- 2015-08-14 ES ES15832083T patent/ES2750689T3/es active Active
- 2015-08-14 CN CN201580042835.6A patent/CN106661578B/zh not_active Expired - Fee Related
- 2015-08-14 EP EP15832083.8A patent/EP3180434B1/en not_active Not-in-force
-
2019
- 2019-03-19 US US16/358,013 patent/US10683502B2/en not_active Expired - Fee Related
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2020
- 2020-05-14 JP JP2020084841A patent/JP2020141688A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20170247694A1 (en) | 2017-08-31 |
| CA2957250A1 (en) | 2016-02-18 |
| JP2020141688A (ja) | 2020-09-10 |
| US10287583B2 (en) | 2019-05-14 |
| EP3180434A1 (en) | 2017-06-21 |
| EP3180434A4 (en) | 2018-04-04 |
| EP3180434B1 (en) | 2019-07-17 |
| EP3626822A1 (en) | 2020-03-25 |
| WO2016025829A1 (en) | 2016-02-18 |
| CN106661578B (zh) | 2020-08-04 |
| JP6705807B2 (ja) | 2020-06-03 |
| PT3180434T (pt) | 2019-10-29 |
| RU2017108238A (ru) | 2018-09-17 |
| US10683502B2 (en) | 2020-06-16 |
| BR112017002629A2 (pt) | 2018-02-20 |
| RU2017108238A3 (enExample) | 2019-09-18 |
| CN106661578A (zh) | 2017-05-10 |
| AU2015301491A1 (en) | 2017-02-02 |
| US20190276825A1 (en) | 2019-09-12 |
| JP2017529834A (ja) | 2017-10-12 |
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