BR112014009238A2 - compostos de (hetero)aril ciclopropilamina como inibidores de lsd1 - Google Patents
compostos de (hetero)aril ciclopropilamina como inibidores de lsd1Info
- Publication number
- BR112014009238A2 BR112014009238A2 BR112014009238A BR112014009238A BR112014009238A2 BR 112014009238 A2 BR112014009238 A2 BR 112014009238A2 BR 112014009238 A BR112014009238 A BR 112014009238A BR 112014009238 A BR112014009238 A BR 112014009238A BR 112014009238 A2 BR112014009238 A2 BR 112014009238A2
- Authority
- BR
- Brazil
- Prior art keywords
- hetero
- lsd1 inhibitors
- compounds
- aryl cyclopropylamine
- cyclopropylamine compounds
- Prior art date
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- C07C211/36—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing at least two amino groups bound to the carbon skeleton
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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Abstract
resumo patente de invenção: "compostos de (hetero)aril ciclopropilamina como inibidores de lsd1". a invenção refere-se aos compostos de (hetero)aril ciclopropilamina, incluindo particularmente os compostos de fórmula i i como descrito e definido aqui, e seu uso em terapia, incluindo, por exemplo, no tratamento ou prevenção do câncer, de uma doença ou condição neurológica, ou de uma infecção viral.
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PCT/EP2012/070900 WO2013057322A1 (en) | 2011-10-20 | 2012-10-22 | (hetero)aryl cyclopropylamine compounds as lsd1 inhibitors |
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