BR112012004289A8 - Célula geneticamente modificada de saccharomyces, e, uso de uma célula - Google Patents

Célula geneticamente modificada de saccharomyces, e, uso de uma célula

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Publication number
BR112012004289A8
BR112012004289A8 BR112012004289A BR112012004289A BR112012004289A8 BR 112012004289 A8 BR112012004289 A8 BR 112012004289A8 BR 112012004289 A BR112012004289 A BR 112012004289A BR 112012004289 A BR112012004289 A BR 112012004289A BR 112012004289 A8 BR112012004289 A8 BR 112012004289A8
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Brazil
Prior art keywords
organism
acyltransferase
cell
diacylglycerol
geneticly
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Application number
BR112012004289A
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English (en)
Other versions
BR112012004289A2 (pt
Inventor
Lang Christine
Raab Andreas
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Organobalance Gmbh
Novozymes As
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Publication date
Application filed by Organobalance Gmbh, Novozymes As filed Critical Organobalance Gmbh
Publication of BR112012004289A2 publication Critical patent/BR112012004289A2/pt
Publication of BR112012004289A8 publication Critical patent/BR112012004289A8/pt

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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
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    • C12N9/0004—Oxidoreductases (1.)
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    • C12N9/10—Transferases (2.)
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    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
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    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01034—Hydroxymethylglutaryl-CoA reductase (NADPH) (1.1.1.34)
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    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/0102—Diacylglycerol O-acyltransferase (2.3.1.20)
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    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01026—Sterol O-acyltransferase (2.3.1.26)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02E50/10—Biofuels, e.g. bio-diesel
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    • Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
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    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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Abstract

ORGANISMOS GENETICAMENTE MODIFICADOS PARA A PRODUÇÃO DE LIPÍDIOS. A presente invenção refere-se a um organismo não mamífero geneticamente modificado isolado, em que a atividade da acil-CoA:esteroi aciltransferase/esterol O-aciltransferase (EC 2.3.1.26) e/ou diaciiglicerol acil- transferase/diacilglicero1 O-aciltranferase (EC 2.3.1.20) e/ou lecitina coleste- rol acil transferase/fosfolipídio: diacilglicerol aciltransferase (EC 2.3.1.158) e/ou acil CoA-álcoo! cera aciltransferase (EC 2.3.1.75) é reduzida ou suprimida em comparação com um organismo do tipo selvagem correspondente, métodos de uso de tal organismo, veículos de transporte para fazer tal organismo e métodos para a produção de tal organismo.
BR112012004289A 2009-08-26 2010-08-04 Célula geneticamente modificada de saccharomyces, e, uso de uma célula BR112012004289A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09075393A EP2292741A1 (en) 2009-08-26 2009-08-26 Genetically modified organisms for the production of lipids
PCT/EP2010/004925 WO2011023298A1 (en) 2009-08-26 2010-08-04 Genetically modified organisms for the production of lipids

Publications (2)

Publication Number Publication Date
BR112012004289A2 BR112012004289A2 (pt) 2015-09-01
BR112012004289A8 true BR112012004289A8 (pt) 2018-02-14

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BR112012004289A BR112012004289A8 (pt) 2009-08-26 2010-08-04 Célula geneticamente modificada de saccharomyces, e, uso de uma célula

Country Status (14)

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US (2) US8841114B2 (pt)
EP (3) EP2292741A1 (pt)
JP (1) JP5954544B2 (pt)
KR (1) KR20120069693A (pt)
CN (1) CN102812124B (pt)
AU (1) AU2010288968B2 (pt)
BR (1) BR112012004289A8 (pt)
CA (1) CA2773030A1 (pt)
ES (2) ES2673548T3 (pt)
IL (1) IL217583A (pt)
MX (1) MX2012002409A (pt)
RU (1) RU2617963C2 (pt)
SG (1) SG178517A1 (pt)
WO (1) WO2011023298A1 (pt)

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CN109200344B (zh) * 2018-10-16 2021-05-18 惠州卫生职业技术学院 一种助产用润滑剂及其制备方法
KR102304145B1 (ko) * 2019-08-22 2021-09-17 세종대학교산학협력단 탈아세틸화용 조성물 및 이를 이용한 탈아세틸화 방법
CN112063647B (zh) * 2020-09-17 2023-05-02 云南农业大学 酿酒酵母重组菌Cuol01的构建方法、酿酒酵母重组菌Cuol02及应用
CN112662688B (zh) * 2021-01-25 2022-04-22 山东省果树研究所 核桃SnRK1蛋白激酶编码基因JrSnRK1在油脂合成与积累中的应用
WO2023057041A1 (en) * 2021-10-04 2023-04-13 Apix Biosciences Methods for delivering 24-methylene cholesterol, isofucosterol, cholesterol or desmosterol to invertebrates, in particular honey bees or bumble bees
BE1029426B1 (nl) * 2021-09-28 2022-12-14 Apix Biosciences Methoden voor de toediening van heilzame voedingsstoffen aan organismen
WO2023052336A1 (en) * 2021-09-28 2023-04-06 Apix Biosciences Methods for delivering 24-methylene cholesterol, isofucosterol, cholesterol or desmosterol to invertebrates, in particular honey bees or bumble bees
CN114344205A (zh) * 2021-11-03 2022-04-15 广西南宁美丝美世纪生物科技有限责任公司 一种芥菜型油菜消炎美容膏剂及其制备方法
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AU2010288968B2 (en) 2016-05-12
BR112012004289A2 (pt) 2015-09-01
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