BR1100650A - Proteìnas de superfìcie cd44 variantes, sequências de dna que as codificam, anticorpos contra estas proteìnas, bem como a sua utilização no diagnóstico e na terapia - Google Patents

Proteìnas de superfìcie cd44 variantes, sequências de dna que as codificam, anticorpos contra estas proteìnas, bem como a sua utilização no diagnóstico e na terapia

Info

Publication number
BR1100650A
BR1100650A BR1100650-1A BR1100650A BR1100650A BR 1100650 A BR1100650 A BR 1100650A BR 1100650 A BR1100650 A BR 1100650A BR 1100650 A BR1100650 A BR 1100650A
Authority
BR
Brazil
Prior art keywords
proteins
diagnosis
therapy
variant
well
Prior art date
Application number
BR1100650-1A
Other languages
English (en)
Portuguese (pt)
Inventor
Peter Herrlich
Helmut Ponta
Ursula Guenthert
Siegfried Matzku
Achim Wenzel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to BR1100650-1A priority Critical patent/BR1100650A/pt
Publication of BR1100650A publication Critical patent/BR1100650A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2884—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD44
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/828—Cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
BR1100650-1A 1990-05-07 1997-05-07 Proteìnas de superfìcie cd44 variantes, sequências de dna que as codificam, anticorpos contra estas proteìnas, bem como a sua utilização no diagnóstico e na terapia BR1100650A (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR1100650-1A BR1100650A (pt) 1990-05-07 1997-05-07 Proteìnas de superfìcie cd44 variantes, sequências de dna que as codificam, anticorpos contra estas proteìnas, bem como a sua utilização no diagnóstico e na terapia

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4014510A DE4014510A1 (de) 1990-05-07 1990-05-07 Variante cd44-oberflaechenproteine, diese kodierende c-dna-sequenzen, antikoerper gegen diese proteine sowie ihre verwendung in der diagnostik und therapie
BR1100650-1A BR1100650A (pt) 1990-05-07 1997-05-07 Proteìnas de superfìcie cd44 variantes, sequências de dna que as codificam, anticorpos contra estas proteìnas, bem como a sua utilização no diagnóstico e na terapia

Publications (1)

Publication Number Publication Date
BR1100650A true BR1100650A (pt) 2000-08-08

Family

ID=6405813

Family Applications (1)

Application Number Title Priority Date Filing Date
BR1100650-1A BR1100650A (pt) 1990-05-07 1997-05-07 Proteìnas de superfìcie cd44 variantes, sequências de dna que as codificam, anticorpos contra estas proteìnas, bem como a sua utilização no diagnóstico e na terapia

Country Status (21)

Country Link
US (3) US5506119A (enExample)
EP (1) EP0531300B1 (enExample)
JP (1) JP3133062B2 (enExample)
KR (1) KR0184691B1 (enExample)
AT (1) ATE106943T1 (enExample)
AU (1) AU646858B2 (enExample)
BR (1) BR1100650A (enExample)
CA (1) CA2082382C (enExample)
DE (2) DE4014510A1 (enExample)
DK (1) DK0531300T3 (enExample)
FI (1) FI106128B (enExample)
HU (1) HU218905B (enExample)
IE (1) IE62096B1 (enExample)
IL (3) IL98024A (enExample)
NO (3) NO309770B1 (enExample)
NZ (1) NZ238056A (enExample)
PT (1) PT97574B (enExample)
TW (1) TW212202B (enExample)
WO (1) WO1991017248A1 (enExample)
YU (1) YU49126B (enExample)
ZA (1) ZA913389B (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002873A (en) * 1989-03-17 1991-03-26 Fred Hutchinson Cancer Research Center DNA sequence encoding a lymphocyte adhesion receptor for high endothelium
US5443750A (en) * 1991-01-16 1995-08-22 The Procter & Gamble Company Detergent compositions with high activity cellulase and softening clays
DE4134982A1 (de) * 1991-10-23 1993-04-29 Kernforschungsz Karlsruhe Verwendung von antikoerper enthaltenden praeparationen zur immunsuppression
WO1994002633A1 (en) * 1992-07-21 1994-02-03 Isis Innovation Limited Diagnostic method
CA2165461A1 (en) * 1993-06-18 1995-01-05 Sirpa Jalkanen Compositions and diagnostic methods using monoclonal antibodies against cd44v6
CA2164728A1 (en) * 1993-06-22 1995-01-05 Helmut Ponta Processes for diagnosing and analysing tumours
DE4320624A1 (de) * 1993-06-22 1995-02-09 Boehringer Ingelheim Int Verfahren zur Diagnose und Analyse von Mammakarzinomen
DE4320623C2 (de) * 1993-06-22 1997-11-20 Boehringer Ingelheim Int Verfahren zur Diagnose und Analyse von Adenokarzinomen
DE4326573A1 (de) * 1993-08-07 1995-02-23 Boehringer Ingelheim Int Durch Exon v5 des CD44-Gens kodierte Polypeptide als Targets für Immuntherapie und Immunszintigraphie von Tumoren
DE4431297A1 (de) * 1994-09-02 1996-03-07 Boehringer Ingelheim Int Monoklonaler Antikörper gegen CD44v6
DE19540515C1 (de) * 1995-10-31 1997-02-06 Boehringer Ingelheim Int Tumortherapie durch adoptiven Transfer CD44v-spezifischer zytotoxischer T-Lymphozyten
DE19653607A1 (de) 1996-12-20 1998-06-25 Boehringer Ingelheim Int Verfahren zur Diagnose und Therapie von Hodgkin-Lymphomen
DE19708713C2 (de) * 1997-03-04 2002-11-28 Boehringer Ingelheim Int Verwendung von anti-CD44 Antikörpern enthaltenden Präparationen zur Behandlung bestimmter Tumore und zur Unterdrückung von Immunreaktionen
US8048416B2 (en) 1999-10-08 2011-11-01 Hoffmann-La Roche Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US20080124327A1 (en) * 1999-10-08 2008-05-29 Arius Research, Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US8071072B2 (en) 1999-10-08 2011-12-06 Hoffmann-La Roche Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US7947496B2 (en) 1999-10-08 2011-05-24 Hoffmann-La Roche Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US20050100542A1 (en) * 1999-10-08 2005-05-12 Young David S. Cytotoxicity mediation of cells evidencing surface expression of CD44
US7189397B2 (en) 1999-10-08 2007-03-13 Arius Research Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US20090004103A1 (en) * 1999-10-08 2009-01-01 Young David S F Cytotoxicity mediation of cells evidencing surface expression of CD44
DE10026833A1 (de) * 2000-05-30 2001-12-13 Karlsruhe Forschzent Verfahren zur Identifizierung von Verbindungen zur Modulierung der Aktivität eines Tumorsuppressorgens
US20040110933A1 (en) * 2002-09-13 2004-06-10 Dyax Corporation CD44-binding ligands
EP2886126B1 (en) 2013-12-23 2017-06-07 Exchange Imaging Technologies GmbH Nanoparticle conjugated to CD44 binding peptides
CN109608536B (zh) * 2018-12-12 2020-09-15 深圳市龙华区人民医院 基于前列腺癌干细胞标志物cd44的抗原表位多肽cd44-p3及其应用
CN109608537B (zh) * 2018-12-12 2020-09-15 深圳市龙华区人民医院 基于前列腺癌干细胞标志物cd44的抗原表位多肽cd44-p2及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753894A (en) * 1984-02-08 1988-06-28 Cetus Corporation Monoclonal anti-human breast cancer antibodies
US5108904A (en) * 1990-03-26 1992-04-28 Alan Landay CD44 as a marker for HIV infection

Also Published As

Publication number Publication date
AU646858B2 (en) 1994-03-10
NO317154B1 (no) 2004-08-30
KR0184691B1 (ko) 1999-04-01
NO309770B1 (no) 2001-03-26
EP0531300B1 (de) 1994-06-08
YU79491A (sh) 1994-06-10
YU49126B (sh) 2004-03-12
ZA913389B (en) 1992-03-25
AU7565991A (en) 1991-11-27
HUT63652A (en) 1993-09-28
CA2082382A1 (en) 1991-11-08
FI106128B (fi) 2000-11-30
US5506119A (en) 1996-04-09
JPH05508309A (ja) 1993-11-25
IL134982A (en) 2004-05-12
PT97574B (pt) 1998-08-31
ATE106943T1 (de) 1994-06-15
PT97574A (pt) 1992-01-31
NO20001668L (no) 1993-05-06
HU218905B (hu) 2000-12-28
FI925043L (fi) 1992-11-06
FI925043A0 (fi) 1992-11-06
TW212202B (enExample) 1993-09-01
NZ238056A (en) 1993-01-27
NO310661B1 (no) 2001-08-06
EP0531300A1 (de) 1993-03-17
WO1991017248A1 (de) 1991-11-14
IL98024A0 (en) 1992-06-21
IL98024A (en) 2001-06-14
US5760178A (en) 1998-06-02
JP3133062B2 (ja) 2001-02-05
HU9203449D0 (en) 1993-01-28
IE62096B1 (en) 1995-01-11
NO980293D0 (no) 1998-01-23
NO924234D0 (no) 1992-11-04
DE59101889D1 (de) 1994-07-14
IL134982A0 (en) 2001-05-20
US5885575A (en) 1999-03-23
DK0531300T3 (da) 1994-10-10
CA2082382C (en) 2008-09-30
DE4014510A1 (de) 1991-11-14
NO20001668D0 (no) 2000-03-31
NO980293L (no) 1993-01-04
IE911526A1 (en) 1991-11-20
NO924234L (no) 1993-01-04

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Legal Events

Date Code Title Description
AN Processing applications according to articles 230 and 231 of law 9279/96: notification of filing an application
HHFK Processing applications according to articles 230 and 231 of law 9.279/96: republication
MT Patent procedure suspended until requirement met - articles 230 and 231 of law 9279/96
TC Change of name
FGAN Processing applications according to articles 230 and 231 of law 9.279/96: granting
NB Patent issued - articles 230 and 231 of law 9279/96