BR0203517A - Composição farmacêutica estéril aquosa, e, método para preparar uma composição farmacêutica estéril aquosa - Google Patents
Composição farmacêutica estéril aquosa, e, método para preparar uma composição farmacêutica estéril aquosaInfo
- Publication number
- BR0203517A BR0203517A BR0203517-0A BR0203517A BR0203517A BR 0203517 A BR0203517 A BR 0203517A BR 0203517 A BR0203517 A BR 0203517A BR 0203517 A BR0203517 A BR 0203517A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical composition
- aqueous sterile
- sterile pharmaceutical
- preparing
- aqueous
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- VZTMYLWJKCAXMZ-UHFFFAOYSA-N 2-[(2-chloroquinazolin-4-yl)amino]ethanol Chemical compound C1=CC=C2C(NCCO)=NC(Cl)=NC2=C1 VZTMYLWJKCAXMZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000006172 buffering agent Substances 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229960001015 esmolol hydrochloride Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000003204 osmotic effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- GXLJZLBKWSJXFP-UHFFFAOYSA-N phenyl propanoate;hydrochloride Chemical compound Cl.CCC(=O)OC1=CC=CC=C1 GXLJZLBKWSJXFP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002572 propoxy group Chemical group [*]OC([H])([H])C(C([H])([H])[H])([H])[H] 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/759,547 US6310094B1 (en) | 2001-01-12 | 2001-01-12 | Ready-to-use esmolol solution |
| US10/016,260 US6528540B2 (en) | 2001-01-12 | 2001-10-30 | Esmolol formulation |
| PCT/US2002/000329 WO2002076446A1 (en) | 2001-01-12 | 2002-01-02 | Esmolol formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0203517A true BR0203517A (pt) | 2003-06-03 |
Family
ID=26688377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0203517-0A BR0203517A (pt) | 2001-01-12 | 2002-01-02 | Composição farmacêutica estéril aquosa, e, método para preparar uma composição farmacêutica estéril aquosa |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1368019B2 (sk) |
| JP (1) | JP2004519506A (sk) |
| CN (1) | CN1298320C (sk) |
| AT (1) | ATE341319T1 (sk) |
| AU (1) | AU2002309475B2 (sk) |
| BR (1) | BR0203517A (sk) |
| CA (1) | CA2410446C (sk) |
| CZ (1) | CZ304290B6 (sk) |
| DE (1) | DE60215129T3 (sk) |
| DK (1) | DK1368019T4 (sk) |
| ES (1) | ES2272720T5 (sk) |
| HU (1) | HUP0204520A3 (sk) |
| IL (1) | IL151359A (sk) |
| MX (1) | MXPA03006229A (sk) |
| PL (1) | PL216192B1 (sk) |
| RU (1) | RU2286774C2 (sk) |
| SI (1) | SI1368019T2 (sk) |
| SK (1) | SK288113B6 (sk) |
| TR (1) | TR200202557T1 (sk) |
| TW (1) | TWI277414B (sk) |
| WO (1) | WO2002076446A1 (sk) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6310094B1 (en) * | 2001-01-12 | 2001-10-30 | Baxter International Inc. | Ready-to-use esmolol solution |
| EP1417962A1 (de) | 2002-11-06 | 2004-05-12 | AOP Orphan Pharmaceuticals AG | Verfahren zur Herstellung eines Arzneimittels enthaltend Esmolol |
| ATE526988T1 (de) * | 2003-10-08 | 2011-10-15 | Mallinckrodt Llc | Methylphenidat-lösung und relevante verabreichungs- und herstellungsverfahren |
| CN1303987C (zh) * | 2004-11-19 | 2007-03-14 | 陈庆财 | 注射用盐酸艾司洛尔冻干粉针剂及其制备方法 |
| US20080293814A1 (en) * | 2007-05-22 | 2008-11-27 | Deepak Tiwari | Concentrate esmolol |
| AU2014203121B2 (en) * | 2007-05-22 | 2016-04-21 | Baxter Healthcare Sa | Concentrate esmolol |
| US8426467B2 (en) * | 2007-05-22 | 2013-04-23 | Baxter International Inc. | Colored esmolol concentrate |
| US8722736B2 (en) * | 2007-05-22 | 2014-05-13 | Baxter International Inc. | Multi-dose concentrate esmolol with benzyl alcohol |
| NZ586200A (en) * | 2007-12-21 | 2012-06-29 | Aop Orphan Pharmaceuticals Ag | Pharmaceutical composition for the parenteral administration of ultrashort-effective beta-adrenoreceptor antagonists |
| ES2443159T3 (es) * | 2009-09-22 | 2014-02-18 | Vlife Sciences Technologies Pvt Ltd. | Formulación tópica para úlceras del pie diabético |
| ES2363964B1 (es) | 2009-11-20 | 2012-08-22 | Gp Pharm, S.A. | Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados. |
| JP2014505074A (ja) * | 2011-01-27 | 2014-02-27 | バクスター・インターナショナル・インコーポレイテッド | 血圧低下を最小化しおよび／または制御しながら頻脈を治療しおよび／または心拍数を制御する方法 |
| US8829047B2 (en) | 2011-01-27 | 2014-09-09 | Baxter International Inc. | Methods of controlling venous irritation associated with the treatment of a cardiac disorder |
| MX2014013556A (es) | 2012-05-10 | 2015-01-16 | Aop Orphan Pharmaceuticals Ag | Formulacion parenteral de esmolol. |
| US8835505B1 (en) | 2013-03-15 | 2014-09-16 | Welgrace Research Group | Ready-to-use co-solvents pharmaceutical composition in modified flexible plastic container |
| CN104473869A (zh) * | 2014-11-20 | 2015-04-01 | 北京京科泰来科技有限公司 | 一种艾司洛尔脂肪乳及其制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4857552A (en) * | 1988-06-08 | 1989-08-15 | E. I. Du Pont De Nemours And Co. | Stable pharmaceutical composition |
| CN1074763C (zh) * | 1997-11-13 | 2001-11-14 | 山东省医药工业研究所 | 艾司洛尔盐酸盐的制备方法 |
-
2001
- 2001-12-14 TW TW090131012A patent/TWI277414B/zh not_active IP Right Cessation
-
2002
- 2002-01-02 RU RU2002132189/15A patent/RU2286774C2/ru active
- 2002-01-02 DE DE60215129T patent/DE60215129T3/de not_active Expired - Lifetime
- 2002-01-02 WO PCT/US2002/000329 patent/WO2002076446A1/en active IP Right Grant
- 2002-01-02 PL PL357387A patent/PL216192B1/pl unknown
- 2002-01-02 SK SK1278-2002A patent/SK288113B6/sk not_active IP Right Cessation
- 2002-01-02 EP EP02736473A patent/EP1368019B2/en not_active Expired - Lifetime
- 2002-01-02 BR BR0203517-0A patent/BR0203517A/pt not_active Application Discontinuation
- 2002-01-02 DK DK02736473.6T patent/DK1368019T4/da active
- 2002-01-02 CN CNB028000676A patent/CN1298320C/zh not_active Expired - Lifetime
- 2002-01-02 JP JP2002574961A patent/JP2004519506A/ja not_active Withdrawn
- 2002-01-02 AU AU2002309475A patent/AU2002309475B2/en not_active Expired
- 2002-01-02 CZ CZ2002-3825A patent/CZ304290B6/cs not_active IP Right Cessation
- 2002-01-02 CA CA002410446A patent/CA2410446C/en not_active Expired - Lifetime
- 2002-01-02 AT AT02736473T patent/ATE341319T1/de active
- 2002-01-02 IL IL151359A patent/IL151359A/en active IP Right Grant
- 2002-01-02 ES ES02736473T patent/ES2272720T5/es not_active Expired - Lifetime
- 2002-01-02 HU HU0204520A patent/HUP0204520A3/hu not_active Application Discontinuation
- 2002-01-02 MX MXPA03006229A patent/MXPA03006229A/es active IP Right Grant
- 2002-01-02 TR TR2002/02557T patent/TR200202557T1/xx unknown
- 2002-01-02 SI SI200230444T patent/SI1368019T2/sl unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |