BR0011839A - Método de produzir derivados de nitroguanidina e nitroenamina - Google Patents
Método de produzir derivados de nitroguanidina e nitroenaminaInfo
- Publication number
- BR0011839A BR0011839A BR0011839-7A BR0011839A BR0011839A BR 0011839 A BR0011839 A BR 0011839A BR 0011839 A BR0011839 A BR 0011839A BR 0011839 A BR0011839 A BR 0011839A
- Authority
- BR
- Brazil
- Prior art keywords
- formula
- alkyl
- hydrogen
- producing
- radical
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/22—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having nitrogen atoms of amidino groups further bound to nitrogen atoms, e.g. hydrazidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C261/00—Derivatives of cyanic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyridine Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
Abstract
Patente de Invenção: "MéTODO DE PRODUZIR DERIVADOS DE NITRO-GUANIDINA E NITROENAMINA". Método de produzir os compostos da fórmula em que R~ 1~ é hidrogênio ou alquila C~ 1~-C~ 4~; R~ 2~ é hidrogênio, alquila C~ 1~-C~ 8~, cicloalquila C~ 3~-C~ 6~ ou um radical -N(R~ 3~)R~ 4~; ou R~ 2~ e R~ 6~ juntos são -CH~ 2~-CH~ 2~-S-; R~ 3~ e R~ 4~ são hidrogênio, alquila C~ 1~-C~ 4~, cicloalquila C~ 3~-C~ 6~ ou um radical -CH~ 2~B; R~ 6~ é hidrogênio, alquila C~ 1~-C~ 8~, arila ou benzila; ou R~ 3~ e R~ 6~ juntos são -CH~ 2~-CH~ 2~-, -CH~ 2~-CH~ 2~-CH~ 2~-, -CH~ 2~-O-CH~ 2~-, -CH~ 2~-S-CH~ 2~ou -CH~ 2~-N(R~ 5~)-CH~ 2~-; X é CH-CN; CH-NO~ 2~ ou N-NO~ 2~; A é um radical heterocíclico aromático ou não aromático, monocíclico ou bicíclico opcionalmente substituído; e B é fenila, 3-piridila ou tiazolila opcionalmente substituída; caracterizado pelo fato de que um composto da fórmula em que R~ 2~, R~ 6~ e X têm o mesmo significado como dado acima na fórmula (I), é reagido na presença de um catalisador de transferência de fase e uma base com um composto da fórmula em que A e R~ 1~ têm o mesmo significado como dado acima na fórmula (I) e Q é um grupo de partida.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH117199 | 1999-06-23 | ||
PCT/EP2000/005762 WO2001000623A1 (en) | 1999-06-23 | 2000-06-21 | Method of producing nitroguanidine- and nitroenamine derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
BR0011839A true BR0011839A (pt) | 2002-03-05 |
BR0011839B1 BR0011839B1 (pt) | 2010-11-03 |
Family
ID=4204160
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0011839-7A BR0011839B1 (pt) | 1999-06-23 | 2000-06-21 | método de produzir derivados de nitroguanidina e nitroenamina. |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP1187833B1 (pt) |
JP (1) | JP4588951B2 (pt) |
KR (1) | KR100644739B1 (pt) |
CN (1) | CN1247572C (pt) |
AR (1) | AR024423A1 (pt) |
AT (1) | ATE364042T1 (pt) |
AU (1) | AU773966B2 (pt) |
BR (1) | BR0011839B1 (pt) |
CA (1) | CA2369404C (pt) |
CY (1) | CY1106743T1 (pt) |
CZ (1) | CZ300093B6 (pt) |
DE (1) | DE60035109T2 (pt) |
DK (1) | DK1187833T3 (pt) |
ES (1) | ES2284506T3 (pt) |
HU (1) | HU228645B1 (pt) |
IL (1) | IL146580A0 (pt) |
MX (1) | MXPA01012639A (pt) |
PL (1) | PL202732B1 (pt) |
PT (1) | PT1187833E (pt) |
RU (1) | RU2258704C2 (pt) |
TW (1) | TWI254713B (pt) |
UA (1) | UA73306C2 (pt) |
WO (1) | WO2001000623A1 (pt) |
ZA (1) | ZA200110388B (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006073973A2 (en) | 2004-12-31 | 2006-07-13 | Reddy Us Therapeutics, Inc. | Novel benzylamine derivatives as cetp inhibitors |
US8604055B2 (en) | 2004-12-31 | 2013-12-10 | Dr. Reddy's Laboratories Ltd. | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors |
DE102008052795B4 (de) | 2008-10-22 | 2012-01-26 | Balchem Corp. | Verfahren zur Herstellung von Fettsäureestern ein- oder mehrwertiger Alkohole unter Verwendung spezieller hydroxyfunktioneller quartärer Ammoniumverbindungen als Katalysatoren |
WO2013024358A2 (en) | 2011-08-18 | 2013-02-21 | Dr. Reddy's Laboratories Ltd. | Substituted heterocyclic amine compounds as cholestryl ester-transfer protein (cetp) inhibitors |
CN103958511A (zh) | 2011-09-27 | 2014-07-30 | 雷迪博士实验室有限公司 | 作为胆固醇酯转移蛋白(CETP)抑制剂用于治疗动脉粥样硬化的5-苄基氨基甲基-6-氨基吡唑并[3,4-b]吡啶衍生物 |
CN102372702A (zh) * | 2011-11-17 | 2012-03-14 | 安徽省化工研究院 | 噻虫嗪的制备方法 |
CN103787922B (zh) * | 2014-03-04 | 2016-06-01 | 新昌县鸿吉电子科技有限公司 | 一种合成硝基取代化合物的工业催化方法 |
CN103880832B (zh) * | 2014-04-04 | 2016-06-15 | 连云港市金囤农化有限公司 | 一种噻虫嗪的制备方法 |
GB2564284A (en) * | 2014-05-28 | 2019-01-09 | Rotam Agrochem Int Co Ltd | Thiamethoxam and uses thereof |
GB2511010B (en) * | 2014-05-28 | 2017-05-03 | Rotam Agrochem Int Co Ltd | Method of producing thiamethoxam |
GB2514927B (en) * | 2014-05-28 | 2019-04-17 | Rotam Agrochem Int Co Ltd | Thiamethoxam and uses thereof |
CN107400123A (zh) * | 2017-08-28 | 2017-11-28 | 江苏绿叶农化有限公司 | 一种噻虫嗪的生产方法 |
EP3480196A1 (en) | 2017-11-02 | 2019-05-08 | Jiangsu Rotam Chemistry Co., Ltd | Process for the preparation of thiamethoxam |
AR124935A1 (es) | 2021-03-01 | 2023-05-24 | Syngenta Crop Protection Ag | Formulaciones plaguicidas |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2822050B2 (ja) * | 1989-02-04 | 1998-11-05 | 日本バイエルアグロケム株式会社 | 2―ニトロイミノイミダゾリジン類の製法 |
JP3159859B2 (ja) * | 1994-02-09 | 2001-04-23 | 日本バイエルアグロケム株式会社 | 殺虫性ニトロ化合物 |
DE19904310A1 (de) * | 1999-01-28 | 2000-08-03 | Bayer Ag | Verfahren zur Herstellung heterocyclischer Verbindungen |
-
2000
- 2000-06-21 KR KR1020017016368A patent/KR100644739B1/ko not_active IP Right Cessation
- 2000-06-21 PL PL352401A patent/PL202732B1/pl unknown
- 2000-06-21 IL IL14658000A patent/IL146580A0/xx active IP Right Grant
- 2000-06-21 PT PT00942115T patent/PT1187833E/pt unknown
- 2000-06-21 MX MXPA01012639A patent/MXPA01012639A/es active IP Right Grant
- 2000-06-21 UA UA2002010571A patent/UA73306C2/uk unknown
- 2000-06-21 TW TW089112156A patent/TWI254713B/zh not_active IP Right Cessation
- 2000-06-21 WO PCT/EP2000/005762 patent/WO2001000623A1/en active IP Right Grant
- 2000-06-21 CZ CZ20014524A patent/CZ300093B6/cs not_active IP Right Cessation
- 2000-06-21 HU HU0202050A patent/HU228645B1/hu unknown
- 2000-06-21 RU RU2002100907/04A patent/RU2258704C2/ru active
- 2000-06-21 JP JP2001507031A patent/JP4588951B2/ja not_active Expired - Lifetime
- 2000-06-21 DE DE60035109T patent/DE60035109T2/de not_active Expired - Lifetime
- 2000-06-21 EP EP00942115A patent/EP1187833B1/en not_active Expired - Lifetime
- 2000-06-21 AT AT00942115T patent/ATE364042T1/de active
- 2000-06-21 AU AU56847/00A patent/AU773966B2/en not_active Ceased
- 2000-06-21 CN CNB008093296A patent/CN1247572C/zh not_active Expired - Lifetime
- 2000-06-21 BR BRPI0011839-7A patent/BR0011839B1/pt not_active IP Right Cessation
- 2000-06-21 AR ARP000103082A patent/AR024423A1/es not_active Application Discontinuation
- 2000-06-21 ES ES00942115T patent/ES2284506T3/es not_active Expired - Lifetime
- 2000-06-21 CA CA2369404A patent/CA2369404C/en not_active Expired - Fee Related
- 2000-06-21 DK DK00942115T patent/DK1187833T3/da active
-
2001
- 2001-12-19 ZA ZA200110388A patent/ZA200110388B/xx unknown
-
2007
- 2007-07-19 CY CY20071100961T patent/CY1106743T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0011839A (pt) | Método de produzir derivados de nitroguanidina e nitroenamina | |
ATE251163T1 (de) | Bicyclische piperidin- und piperazin-verbindungen mit 5-ht6-rezeptor-affinität | |
BRPI0407283A (pt) | Composto, composição farmacêutica, e, agente ativador de glucoquinase, agentes terapêuticos e/ou agentes preventivos para diabetes melito e obesidade | |
BRPI0519058A2 (pt) | composto ou um sal prà-droga farmaceuticamente aceitÁvel do mesmo, mÉtodos para produzir uma inibiÇço da atividade de dgat1 e para tratar diabete melito e/ou obesidade em um animal de sangue quente, uso de um composto, composiÇço farmacÊutica, e, processo para preparar um composto | |
BRPI0517232A (pt) | composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, ativador da glicocinase, e, agentes terapêuticos e/ou profiláticos para diabetes e para obesidade | |
BR0109703A (pt) | Derivados de piperazina | |
BR0010391A (pt) | Composto, composição farmacêutica, método de preparação de um composto, e, uso de um composto | |
BR0317705A (pt) | Composto, formulação farmacêutica, uso de um composto, método de tratamento de doenças ou condições, e, processo para a preparação de compostos | |
WO2003057225A3 (en) | Phosphate transport inhibitors | |
NO20070378L (no) | Bis(tio-hydrazidamid)-salter for behandling av kreft | |
BRPI0615111B8 (pt) | composto, composição farmacêutica, e, uso do composto | |
BR0015466A (pt) | Composto, prodroga, composição farmacêutica, agentes para evitar ou tratar diabetes mellitus, hiperlipidemia e toler ncia à glicose prejudicada, para regular a função do receptor relacionado a retinóide e para melhorar a resistência à insulina e uso de um composto | |
BR9810592A (pt) | Composto, processos para preparar um composto, para tratar ou prevenir doenças do sistema endócrino e para a fabricação de um medicamento, composição farmacêutica, e, uso de um composto | |
NO20023218D0 (no) | 2-amino-nikotinamidderivater og deres anvendelse som VEGF- reseptor tyrosinkinaseinhibitorer | |
WO2003061768A3 (fr) | Utilisation d'un compose inactivant la proteine kinase a dans une composition contenant un milieu cosmetiquement acceptable, pour eclaircir la peau | |
EP1614676A4 (en) | PHOSPHORUS TRANSPORT IN VIVO INHIBITOR COMPOUND AND MEDICAMENT CONTAINING THE SAME | |
NO20071140L (no) | Nye piperidinderivater som histamin H3 reseptorligander for behandling av depresjon | |
BR0209129A (pt) | Compostos, composições farmacêuticas, métodos para tratamento de dores, métodos para modulação de uma resposta farmacológica e usos de compostos | |
NO20054787D0 (no) | Indenderivater som farmasotiske midler | |
BR0012970A (pt) | Compostos e composições antipicornavirais, seus usos farmacêuticos e materiais para a sua sìntese | |
NO20032841L (no) | Heterocykloindol- eller azaindol-forbindelser som 5- hydroksytryptamin-6-ligander | |
BR0210531A (pt) | Derivados de ácido sulfÈnico | |
BR0308419A (pt) | Derivados de azetidina como antagonistas do receptor ccr-3 | |
DK0609289T3 (da) | Imidazolderivater og farmaceutiske præparater med indhold deraf | |
BR9809496A (pt) | Composto, processo para produzi-lo, uso do mesmo, preparação farmacêutica, e, processo para tratar pacientes necessitados de tratamento. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 03/11/2010, OBSERVADAS AS CONDICOES LEGAIS. |
|
B21A | Patent or certificate of addition expired [chapter 21.1 patent gazette] |
Free format text: PATENTE EXTINTA EM 03.11.2020 |