BR0011105A - Derivado de ácido carboxìlico, uso de um derivado combinação, e, preparação farmacêutica para uso oral, parenteral ou intraperitoneal - Google Patents
Derivado de ácido carboxìlico, uso de um derivado combinação, e, preparação farmacêutica para uso oral, parenteral ou intraperitonealInfo
- Publication number
- BR0011105A BR0011105A BR0011105-8A BR0011105A BR0011105A BR 0011105 A BR0011105 A BR 0011105A BR 0011105 A BR0011105 A BR 0011105A BR 0011105 A BR0011105 A BR 0011105A
- Authority
- BR
- Brazil
- Prior art keywords
- derivative
- carboxylic acid
- parenteral
- oral
- pharmaceutical preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/30—Only oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"DERIVADO DE áCIDO CARBOXìLICO, USO DE UM DERIVADO COMBINAçãO, E, PREPARAçãO FARMACêUTICA PARA USO ORAL, PARENTERAL OU INTRAPERITONEAL". A invenção refere-se aos derivados de ácido carboxílico de fórmula (I): cujos os substituintes apresentam os significados explicados na descrição. A invenção também se refere à produção e ao uso de citados novos derivados de ácido carboxílico como antagonistas de receptor de endotelina.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19924892A DE19924892A1 (de) | 1999-06-01 | 1999-06-01 | Neue Carbonsäurederivate mit arylsubstituierten Stickstoffheterocyclen, ihre Herstellung und Verwendung als Endothelin Rezeptorantagonisten |
PCT/EP2000/004571 WO2000073276A2 (de) | 1999-06-01 | 2000-05-19 | Carbonsäurederivate mit arylsubstituierten stickstoffheterocyclen, ihre herstellung und verwendung als endothelin-rezeptor-antagonisten |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0011105A true BR0011105A (pt) | 2002-03-05 |
Family
ID=7909761
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0011105-8A BR0011105A (pt) | 1999-06-01 | 2000-05-19 | Derivado de ácido carboxìlico, uso de um derivado combinação, e, preparação farmacêutica para uso oral, parenteral ou intraperitoneal |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP1181281A2 (pt) |
JP (1) | JP2003500476A (pt) |
KR (1) | KR20020006049A (pt) |
CN (1) | CN1359376A (pt) |
AR (1) | AR022047A1 (pt) |
AU (1) | AU765345B2 (pt) |
BG (1) | BG106154A (pt) |
BR (1) | BR0011105A (pt) |
CA (1) | CA2375666A1 (pt) |
CZ (1) | CZ20014312A3 (pt) |
DE (1) | DE19924892A1 (pt) |
HK (1) | HK1047102A1 (pt) |
HU (1) | HUP0201387A3 (pt) |
IL (1) | IL146800A0 (pt) |
MX (1) | MXPA01012284A (pt) |
NO (1) | NO20015762L (pt) |
PL (1) | PL355112A1 (pt) |
SK (1) | SK17552001A3 (pt) |
TR (1) | TR200103475T2 (pt) |
WO (1) | WO2000073276A2 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2010240142A1 (en) * | 2009-04-22 | 2011-11-10 | Astellas Pharma Inc. | Carboxylic acid compound |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL130251A0 (en) * | 1996-12-18 | 2000-06-01 | Basf Ag | Heterocyclic carboxylic acid derivatives the production and use thereof as endothelin receptor antagonists |
DE19726146A1 (de) * | 1997-06-19 | 1998-12-24 | Basf Ag | Neue ß-Amino und ß-Azidopcarbonsäurederivate, ihre Herstellung und Verwendung als Endothelinrezeptorantagonisten |
EP1009741A1 (de) * | 1997-09-04 | 2000-06-21 | Basf Aktiengesellschaft | Neue carbonsäurederivate, ihre herstellung und verwendung als gemischte et a?/et b?-endothelin-rezeptorantagonisten |
DE19806438A1 (de) * | 1998-02-17 | 1999-08-19 | Basf Ag | Neue Carbonsäurederivate mit 5-substituiertem Pyrimidinring, ihre Herstellung und Verwendung |
DE19809144A1 (de) * | 1998-03-04 | 1999-09-09 | Basf Ag | Neue unsymmetrisch substituierte Carbonsäurederivate, ihre Herstellung und Verwendung als gemischte ET¶LAMBDA¶/ET¶B¶-Rezeptorantagonisten |
DE19836044A1 (de) * | 1998-08-10 | 2000-02-17 | Basf Ag | Neue Carbonsäurederivate, die Ketoseitenketten tragen, ihre Herstellung und Verwendung als Endothelin-Rezeptorantagonisten |
-
1999
- 1999-06-01 DE DE19924892A patent/DE19924892A1/de not_active Withdrawn
-
2000
- 2000-05-19 JP JP2000621342A patent/JP2003500476A/ja active Pending
- 2000-05-19 HU HU0201387A patent/HUP0201387A3/hu unknown
- 2000-05-19 EP EP00938660A patent/EP1181281A2/de not_active Withdrawn
- 2000-05-19 TR TR2001/03475T patent/TR200103475T2/xx unknown
- 2000-05-19 SK SK1755-2001A patent/SK17552001A3/sk unknown
- 2000-05-19 CN CN00809738A patent/CN1359376A/zh active Pending
- 2000-05-19 CA CA002375666A patent/CA2375666A1/en not_active Abandoned
- 2000-05-19 MX MXPA01012284A patent/MXPA01012284A/es unknown
- 2000-05-19 AU AU53959/00A patent/AU765345B2/en not_active Ceased
- 2000-05-19 IL IL14680000A patent/IL146800A0/xx unknown
- 2000-05-19 PL PL00355112A patent/PL355112A1/xx not_active Application Discontinuation
- 2000-05-19 KR KR1020017015482A patent/KR20020006049A/ko not_active Application Discontinuation
- 2000-05-19 CZ CZ20014312A patent/CZ20014312A3/cs unknown
- 2000-05-19 WO PCT/EP2000/004571 patent/WO2000073276A2/de not_active Application Discontinuation
- 2000-05-19 BR BR0011105-8A patent/BR0011105A/pt not_active IP Right Cessation
- 2000-05-30 AR ARP000102660A patent/AR022047A1/es unknown
-
2001
- 2001-11-26 NO NO20015762A patent/NO20015762L/no not_active Application Discontinuation
- 2001-11-27 BG BG106154A patent/BG106154A/xx unknown
-
2002
- 2002-11-29 HK HK02108677.1A patent/HK1047102A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
SK17552001A3 (sk) | 2002-08-06 |
WO2000073276A2 (de) | 2000-12-07 |
IL146800A0 (en) | 2002-07-25 |
PL355112A1 (en) | 2004-04-05 |
AU765345B2 (en) | 2003-09-18 |
CZ20014312A3 (cs) | 2003-02-12 |
DE19924892A1 (de) | 2000-12-07 |
HUP0201387A2 (en) | 2002-08-28 |
WO2000073276A3 (de) | 2001-05-10 |
AU5395900A (en) | 2000-12-18 |
HUP0201387A3 (en) | 2004-12-28 |
KR20020006049A (ko) | 2002-01-18 |
AR022047A1 (es) | 2002-09-04 |
EP1181281A2 (de) | 2002-02-27 |
NO20015762L (no) | 2001-12-13 |
JP2003500476A (ja) | 2003-01-07 |
HK1047102A1 (zh) | 2003-02-07 |
CN1359376A (zh) | 2002-07-17 |
NO20015762D0 (no) | 2001-11-26 |
CA2375666A1 (en) | 2000-12-07 |
MXPA01012284A (es) | 2002-07-30 |
TR200103475T2 (tr) | 2002-04-22 |
BG106154A (en) | 2002-08-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Free format text: ABBOTT GMBH & CO KG. (DE) |
|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1927 DE 11/12/2007. |