BG64311B1 - Метод за получаване на заместени тиазолидиндиони - Google Patents
Метод за получаване на заместени тиазолидиндиони Download PDFInfo
- Publication number
- BG64311B1 BG64311B1 BG103735A BG10373599A BG64311B1 BG 64311 B1 BG64311 B1 BG 64311B1 BG 103735 A BG103735 A BG 103735A BG 10373599 A BG10373599 A BG 10373599A BG 64311 B1 BG64311 B1 BG 64311B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- borohydride
- reducing agent
- lithium
- pyridyl
- ethoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9703334.4A GB9703334D0 (en) | 1997-02-18 | 1997-02-18 | Novel compounds |
| GBGB9703338.5A GB9703338D0 (en) | 1997-02-18 | 1997-02-18 | Novel process |
| GBGB9703310.4A GB9703310D0 (en) | 1997-02-18 | 1997-02-18 | Novel process |
| PCT/EP1998/000818 WO1998037073A1 (fr) | 1997-02-18 | 1998-02-13 | Procede de preparation de thiazolioinedione substituee |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG103735A BG103735A (en) | 2000-06-30 |
| BG64311B1 true BG64311B1 (bg) | 2004-09-30 |
Family
ID=27268725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG103735A BG64311B1 (bg) | 1997-02-18 | 1999-09-15 | Метод за получаване на заместени тиазолидиндиони |
Country Status (29)
| Country | Link |
|---|---|
| EP (2) | EP1770092A1 (fr) |
| JP (2) | JP2001514619A (fr) |
| KR (1) | KR20000071138A (fr) |
| CN (1) | CN1252065A (fr) |
| AP (1) | AP1359A (fr) |
| AR (1) | AR011447A1 (fr) |
| AU (1) | AU6622398A (fr) |
| BG (1) | BG64311B1 (fr) |
| BR (1) | BR9807395A (fr) |
| CA (1) | CA2281695C (fr) |
| CZ (1) | CZ296272B6 (fr) |
| DZ (1) | DZ2430A1 (fr) |
| EA (1) | EA199900754A1 (fr) |
| HU (1) | HUP0001459A3 (fr) |
| ID (1) | ID22222A (fr) |
| IL (1) | IL131392A (fr) |
| IN (1) | IN188379B (fr) |
| MA (1) | MA24475A1 (fr) |
| MY (1) | MY129475A (fr) |
| NO (2) | NO313290B1 (fr) |
| NZ (1) | NZ337179A (fr) |
| OA (1) | OA11148A (fr) |
| PE (1) | PE71899A1 (fr) |
| PL (1) | PL195482B1 (fr) |
| SK (2) | SK287512B6 (fr) |
| TR (1) | TR199902019T2 (fr) |
| TW (1) | TWI222446B (fr) |
| UY (1) | UY24886A1 (fr) |
| WO (1) | WO1998037073A1 (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7091359B2 (en) | 1997-11-04 | 2006-08-15 | Smithkline Beecham Plc | Process for the preparation of thiazolidinedione derivatives |
| GB9723295D0 (en) | 1997-11-04 | 1998-01-07 | Smithkline Beecham Plc | Novel process |
| PL351684A1 (en) * | 1999-04-23 | 2003-06-02 | Smithkline Beecham Plc | Polymorph of 5−[4−[2− (n−methyl−n−( 2−pyridyl)amino) ethoxy]benzyl] thiazolidine−2,4−dione, maleic acid salt |
| FR2820741A1 (fr) * | 2001-02-14 | 2002-08-16 | Ppg Sipsy | Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine |
| FR2820742B1 (fr) * | 2001-02-14 | 2005-03-11 | Ppg Sipsy | Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine |
| KR20050085115A (ko) | 2002-11-22 | 2005-08-29 | 스미스클라인 비참 코포레이션 | 신규 화합물 |
| AR047541A1 (es) * | 2004-02-13 | 2006-01-25 | Sandoz Ag | Fosfato de 5-[[4-[2-metil-2-piridinil-amino-etoxi]fenil]metil]-2,4 tiazolidinadiona (rosiglitazona) y sus formas polimorficas |
| CA2566352A1 (fr) * | 2004-05-12 | 2005-11-17 | Medichem S.A. | Procede de preparation de rosiglitazone |
| CZ297266B6 (cs) * | 2004-09-10 | 2006-10-11 | Zentiva, A. S. | Zpusob prípravy rosiglitazonu |
| CZ297347B6 (cs) * | 2004-09-21 | 2006-11-15 | Zentiva, A. S. | Zpusob prípravy rosiglitazonu |
| CZ298424B6 (cs) * | 2005-05-24 | 2007-09-26 | Zentiva, A. S. | Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1003445B (zh) * | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物，其制备方法和用途 |
| DE3856378T2 (de) * | 1987-09-04 | 2000-05-11 | Beecham Group Plc | Substituierte Thiazolidindionderivate |
| JPH0377875A (ja) * | 1989-08-18 | 1991-04-03 | Kaken Pharmaceut Co Ltd | チアゾリジン‐２，４‐ジオン誘導体およびその製造法 |
| EP0454501B1 (fr) * | 1990-04-27 | 2001-09-05 | Sankyo Company Limited | Dérivés de benzylidène thiazolidines, leur préparation et leur utilisation pour l'inhibition de péroxydes lipidiques |
| US5585495A (en) * | 1991-12-20 | 1996-12-17 | The Upjohn Company | Reduction method for substituted 5-methylene-thiazolidinediones |
| JPH08157473A (ja) * | 1994-10-06 | 1996-06-18 | Nissan Chem Ind Ltd | ピラゾール系チアゾリジン類 |
| JPH08217717A (ja) * | 1995-02-10 | 1996-08-27 | Sumitomo Chem Co Ltd | 環状ケトン系化合物、その製造法およびそれを有効成分とするゴキブリ誘引剤 |
| CN1065243C (zh) * | 1995-05-31 | 2001-05-02 | 住友制药株式会社 | 新的二氮杂萘衍生物 |
-
1998
- 1998-02-11 UY UY24886A patent/UY24886A1/es not_active Application Discontinuation
- 1998-02-13 KR KR1019997007427A patent/KR20000071138A/ko not_active Application Discontinuation
- 1998-02-13 SK SK63-2007A patent/SK287512B6/sk not_active IP Right Cessation
- 1998-02-13 IL IL13139298A patent/IL131392A/xx unknown
- 1998-02-13 NZ NZ337179A patent/NZ337179A/en not_active IP Right Cessation
- 1998-02-13 BR BR9807395-8A patent/BR9807395A/pt not_active Application Discontinuation
- 1998-02-13 AU AU66223/98A patent/AU6622398A/en not_active Abandoned
- 1998-02-13 EP EP06002536A patent/EP1770092A1/fr not_active Withdrawn
- 1998-02-13 WO PCT/EP1998/000818 patent/WO1998037073A1/fr not_active Application Discontinuation
- 1998-02-13 AP APAP/P/1999/001626A patent/AP1359A/en active
- 1998-02-13 ID IDW990876A patent/ID22222A/id unknown
- 1998-02-13 SK SK1120-99A patent/SK285979B6/sk not_active IP Right Cessation
- 1998-02-13 EA EA199900754A patent/EA199900754A1/ru unknown
- 1998-02-13 CN CN98804121A patent/CN1252065A/zh active Pending
- 1998-02-13 PL PL98335163A patent/PL195482B1/pl not_active IP Right Cessation
- 1998-02-13 EP EP98908093A patent/EP0970063A1/fr not_active Withdrawn
- 1998-02-13 CA CA002281695A patent/CA2281695C/fr not_active Expired - Fee Related
- 1998-02-13 TR TR1999/02019T patent/TR199902019T2/xx unknown
- 1998-02-13 HU HU0001459A patent/HUP0001459A3/hu unknown
- 1998-02-13 JP JP53622998A patent/JP2001514619A/ja not_active Withdrawn
- 1998-02-13 CZ CZ0292499A patent/CZ296272B6/cs not_active IP Right Cessation
- 1998-02-14 MY MYPI98000629A patent/MY129475A/en unknown
- 1998-02-16 PE PE1998000107A patent/PE71899A1/es not_active Application Discontinuation
- 1998-02-16 AR ARP980100684A patent/AR011447A1/es active IP Right Grant
- 1998-02-16 MA MA24966A patent/MA24475A1/fr unknown
- 1998-02-17 DZ DZ980040A patent/DZ2430A1/fr active
- 1998-02-18 IN IN417DE1998 patent/IN188379B/en unknown
- 1998-03-11 TW TW087103522A patent/TWI222446B/zh active
-
1999
- 1999-08-17 NO NO19993949A patent/NO313290B1/no not_active IP Right Cessation
- 1999-08-18 OA OA9900183A patent/OA11148A/en unknown
- 1999-09-15 BG BG103735A patent/BG64311B1/bg unknown
-
2002
- 2002-08-19 NO NO20023937A patent/NO20023937D0/no not_active Application Discontinuation
-
2008
- 2008-11-20 JP JP2008296785A patent/JP2009149616A/ja active Pending
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