BG64282B1 - Пироло[2,3-d]пиримидини и използван...'о им ка'о инхиби'ори на 'ирозин киназа - Google Patents

Пироло[2,3-d]пиримидини и използван...'о им ка'о инхиби'ори на 'ирозин киназа Download PDF

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Publication number
BG64282B1
BG64282B1 BG103785A BG10378599A BG64282B1 BG 64282 B1 BG64282 B1 BG 64282B1 BG 103785 A BG103785 A BG 103785A BG 10378599 A BG10378599 A BG 10378599A BG 64282 B1 BG64282 B1 BG 64282B1
Authority
BG
Bulgaria
Prior art keywords
phenyl
group
optionally substituted
alkyl
pyrrolo
Prior art date
Application number
BG103785A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG103785A (en
Inventor
David J. Calderwood
David N. Johnston
Paul Rafferty
Helen L. Twigger
Rainer Munschauer
Lee Arnold
Original Assignee
Abbott Gmbh & Co.Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Abbott Gmbh & Co.Kg filed Critical Abbott Gmbh & Co.Kg
Publication of BG103785A publication Critical patent/BG103785A/xx
Publication of BG64282B1 publication Critical patent/BG64282B1/bg

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG103785A 1997-03-19 1999-10-07 Пироло[2,3-d]пиримидини и използван...'о им ка'о инхиби'ори на 'ирозин киназа BG64282B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4083697P 1997-03-19 1997-03-19
PCT/EP1998/001357 WO1998041525A1 (en) 1997-03-19 1998-03-09 Pyrrolo[2,3d]pyrimidines and their use as tyrosine kinase inhibitors

Publications (2)

Publication Number Publication Date
BG103785A BG103785A (en) 2000-06-30
BG64282B1 true BG64282B1 (bg) 2004-08-31

Family

ID=21913242

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103785A BG64282B1 (bg) 1997-03-19 1999-10-07 Пироло[2,3-d]пиримидини и използван...'о им ка'о инхиби'ори на 'ирозин киназа

Country Status (23)

Country Link
US (1) US6001839A (sk)
EP (1) EP0970084B1 (sk)
JP (1) JP2001516353A (sk)
KR (1) KR20000076426A (sk)
CN (1) CN1134439C (sk)
AT (1) ATE242245T1 (sk)
AU (1) AU748884B2 (sk)
BG (1) BG64282B1 (sk)
BR (1) BR9808281A (sk)
CA (1) CA2283961A1 (sk)
DE (1) DE69815317T2 (sk)
DK (1) DK0970084T3 (sk)
ES (1) ES2202827T3 (sk)
HU (1) HUP0001507A3 (sk)
ID (1) ID24653A (sk)
IL (1) IL131582A0 (sk)
NO (1) NO313962B1 (sk)
NZ (1) NZ337529A (sk)
PL (1) PL335685A1 (sk)
PT (1) PT970084E (sk)
SK (1) SK125999A3 (sk)
TR (1) TR199902301T2 (sk)
WO (1) WO1998041525A1 (sk)

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Publication number Publication date
IL131582A0 (en) 2001-01-28
NZ337529A (en) 2000-10-27
TR199902301T2 (xx) 1999-12-21
KR20000076426A (ko) 2000-12-26
WO1998041525A1 (en) 1998-09-24
BG103785A (en) 2000-06-30
HUP0001507A2 (hu) 2000-10-28
NO994509L (no) 1999-09-17
NO994509D0 (no) 1999-09-17
CN1134439C (zh) 2004-01-14
JP2001516353A (ja) 2001-09-25
SK125999A3 (en) 2000-05-16
DE69815317D1 (de) 2003-07-10
PT970084E (pt) 2003-10-31
AU748884B2 (en) 2002-06-13
AU6829398A (en) 1998-10-12
PL335685A1 (en) 2000-05-08
CN1259950A (zh) 2000-07-12
ATE242245T1 (de) 2003-06-15
DK0970084T3 (da) 2003-09-29
ID24653A (id) 2000-07-27
BR9808281A (pt) 2000-05-16
US6001839A (en) 1999-12-14
EP0970084A1 (en) 2000-01-12
CA2283961A1 (en) 1998-09-24
DE69815317T2 (de) 2005-04-07
NO313962B1 (no) 2003-01-06
EP0970084B1 (en) 2003-06-04
HUP0001507A3 (en) 2002-01-28
ES2202827T3 (es) 2004-04-01

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