BG64213B1 - Глюкокортикоидселективни противовъзпалителни средства - Google Patents

Глюкокортикоидселективни противовъзпалителни средства Download PDF

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Publication number
BG64213B1
BG64213B1 BG104698A BG10469800A BG64213B1 BG 64213 B1 BG64213 B1 BG 64213B1 BG 104698 A BG104698 A BG 104698A BG 10469800 A BG10469800 A BG 10469800A BG 64213 B1 BG64213 B1 BG 64213B1
Authority
BG
Bulgaria
Prior art keywords
carbon atoms
twelve carbon
twelve
alkyl
aryl
Prior art date
Application number
BG104698A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG104698A (en
Inventor
Michael J. Coughlan
Michael E. Kort
James P. Edwards
Todd K. Jones
Original Assignee
Abbott Laboratories
Ligand Pharmaceuticals,Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories, Ligand Pharmaceuticals,Inc filed Critical Abbott Laboratories
Publication of BG104698A publication Critical patent/BG104698A/xx
Publication of BG64213B1 publication Critical patent/BG64213B1/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cosmetics (AREA)
  • Cephalosporin Compounds (AREA)
BG104698A 1998-02-13 2000-08-17 Глюкокортикоидселективни противовъзпалителни средства BG64213B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/023,913 US6380207B2 (en) 1998-02-13 1998-02-13 Glucocortiocoid-selective antiinflammatory agents
PCT/US1999/003210 WO1999041257A1 (en) 1998-02-13 1999-02-15 Glucocorticoid-selective antiinflammatory agents

Publications (2)

Publication Number Publication Date
BG104698A BG104698A (en) 2001-05-31
BG64213B1 true BG64213B1 (bg) 2004-05-31

Family

ID=21817891

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104698A BG64213B1 (bg) 1998-02-13 2000-08-17 Глюкокортикоидселективни противовъзпалителни средства

Country Status (24)

Country Link
US (1) US6380207B2 (de)
EP (1) EP1053240B1 (de)
JP (1) JP2002503666A (de)
KR (1) KR20010040940A (de)
CN (1) CN1153771C (de)
AT (1) ATE237620T1 (de)
AU (1) AU760511B2 (de)
BG (1) BG64213B1 (de)
BR (1) BR9907847A (de)
CA (1) CA2320911A1 (de)
DE (1) DE69906938T2 (de)
DK (1) DK1053240T3 (de)
ES (1) ES2197618T3 (de)
HK (1) HK1033309A1 (de)
HU (1) HUP0100846A3 (de)
IL (1) IL137509A0 (de)
NO (1) NO20004052L (de)
NZ (1) NZ506012A (de)
PL (1) PL342999A1 (de)
PT (1) PT1053240E (de)
SK (1) SK284076B6 (de)
TR (1) TR200002345T2 (de)
WO (1) WO1999041257A1 (de)
ZA (1) ZA99533B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566372B1 (en) * 1999-08-27 2003-05-20 Ligand Pharmaceuticals Incorporated Bicyclic androgen and progesterone receptor modulator compounds and methods
DE60113032T2 (de) 2000-10-30 2006-07-06 Pfizer Products Inc., Groton Glukokortikoidrezeptor-Modulatoren
US7026484B2 (en) * 2001-02-23 2006-04-11 Ligand Pharmaceuticals Incorporated Tricyclic androgen receptor modulator compounds and methods
JP4745609B2 (ja) 2002-01-22 2011-08-10 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア グルココルチコイドレセプターのための非ステロイド性リガンド、その組成物および使用
KR100492913B1 (ko) * 2002-08-23 2005-06-03 주식회사 태평양 피부 감작 및 자극을 완화하는 피부 외용제 조성물
WO2004019953A1 (en) 2002-08-28 2004-03-11 Hollis-Eden Pharmaceuticals, Inc. Therapeutic treatment methods
US20040220153A1 (en) * 2002-09-24 2004-11-04 Jost-Price Edward Roydon Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
DE20301728U1 (de) * 2002-10-11 2004-03-11 Ligand Pharmaceuticals, Inc., San Diego 5-substituierte 7,9-Difluor-5H-Chromeno(3,4-f) -Chinolin-Verbindungen als selektive Progesteronrezeptormodulator-Verbindungen
EP1558618A1 (de) * 2002-10-11 2005-08-03 Ligand Pharmaceuticals, Inc. 5-(1Ü,1Ü-CYCLOALKYL/ALKENYL)METHYLIDEN-1,2-DIHYDRO-5H-CHROMENOç3,4-F!CHINOLINEALS DEN PROGESTERONREZEPTOR SELEKTIV MODULIERENDE VERBINDUNGEN
EP1551845A1 (de) * 2002-10-11 2005-07-13 Ligand Pharmaceuticals, Inc. 5-CYCLOALKENYLç5H!CHROMENOç3,4-F!CHINOLINDERIVATE ALS SELEKTIVE, DEN PROGESTERONREZEPTOR MODULIERENDE VERBINDUNGEN
US7235662B2 (en) * 2003-06-11 2007-06-26 Bristol-Myers Squibb Company Modulators of the glucocorticoid receptor and method
CN1838956A (zh) 2003-08-22 2006-09-27 配体药物公司 作为雄激素受体调节剂化合物的6－环氨基－2－喹啉酮衍生物
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
EP1689390B1 (de) 2003-11-21 2011-02-09 Zalicus Inc. Verfahren und reagenzien zur behandlung von entzündlichen erkrankungen
WO2005090282A1 (en) 2004-03-12 2005-09-29 Ligand Pharmaceuticals Incorporated Androgen receptor modulator compounds and methods
BRPI0609191B8 (pt) * 2005-06-17 2021-05-25 Ligand Pharm Inc métodos e compostos moduladores de receptor de androgênio
JP2009506077A (ja) 2005-08-26 2009-02-12 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 非ステロイド性抗アンドロゲン剤
AU2006311577B2 (en) 2005-11-09 2013-02-07 Zalicus Inc. Methods, compositions, and kits for the treatment of medical conditions
KR101025139B1 (ko) * 2005-12-09 2011-03-31 에프. 호프만-라 로슈 아게 항염증제로서의 프로피온아미드 화합물
JP4980366B2 (ja) * 2005-12-09 2012-07-18 エフ．ホフマン−ラ ロシュ アーゲー 抗炎症剤としてのグルココルチコイド受容体モジュレーター
US20100092479A1 (en) * 2008-08-18 2010-04-15 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
US9908182B2 (en) 2012-01-30 2018-03-06 Black & Decker Inc. Remote programming of a power tool
US8919456B2 (en) 2012-06-08 2014-12-30 Black & Decker Inc. Fastener setting algorithm for drill driver
US10011006B2 (en) 2013-08-08 2018-07-03 Black & Decker Inc. Fastener setting algorithm for drill driver

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69531998T2 (de) 1994-12-22 2004-07-22 Ligand Pharmaceuticals, Inc., San Diego Steroidrezeptor-modulator verbindungen und methoden
US5688810A (en) 1994-12-22 1997-11-18 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
US5693133A (en) 1995-05-10 1997-12-02 Akzo Nobel Nv Asbestos free roof coatings

Also Published As

Publication number Publication date
CN1153771C (zh) 2004-06-16
DE69906938T2 (de) 2004-02-26
HK1033309A1 (en) 2001-08-24
HUP0100846A2 (hu) 2001-09-28
PL342999A1 (en) 2001-07-16
EP1053240A1 (de) 2000-11-22
AU2600399A (en) 1999-08-30
ES2197618T3 (es) 2004-01-01
NZ506012A (en) 2003-03-28
BR9907847A (pt) 2001-01-09
SK284076B6 (sk) 2004-09-08
SK11962000A3 (sk) 2001-03-12
CA2320911A1 (en) 1999-08-19
HUP0100846A3 (en) 2003-03-28
DK1053240T3 (da) 2003-08-11
NO20004052L (no) 2000-10-12
US20010049377A1 (en) 2001-12-06
ATE237620T1 (de) 2003-05-15
WO1999041257A1 (en) 1999-08-19
BG104698A (en) 2001-05-31
ZA99533B (en) 1999-07-26
EP1053240B1 (de) 2003-04-16
DE69906938D1 (de) 2003-05-22
JP2002503666A (ja) 2002-02-05
PT1053240E (pt) 2003-09-30
AU760511B2 (en) 2003-05-15
IL137509A0 (en) 2001-07-24
CN1297451A (zh) 2001-05-30
KR20010040940A (ko) 2001-05-15
TR200002345T2 (tr) 2000-11-21
NO20004052D0 (no) 2000-08-11
US6380207B2 (en) 2002-04-30

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