DE69906938D1 - Glococorticoid selektive entzündungshemmende mittel - Google Patents

Glococorticoid selektive entzündungshemmende mittel

Info

Publication number
DE69906938D1
DE69906938D1 DE69906938T DE69906938T DE69906938D1 DE 69906938 D1 DE69906938 D1 DE 69906938D1 DE 69906938 T DE69906938 T DE 69906938T DE 69906938 T DE69906938 T DE 69906938T DE 69906938 D1 DE69906938 D1 DE 69906938D1
Authority
DE
Germany
Prior art keywords
glococorticoid
flamming
agents
mammal
selective anti
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69906938T
Other languages
English (en)
Other versions
DE69906938T2 (de
Inventor
J Coughlan
E Kort
P Edwards
K Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Ligand Pharmaceuticals Inc
Original Assignee
Abbott Laboratories
Ligand Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories, Ligand Pharmaceuticals Inc filed Critical Abbott Laboratories
Publication of DE69906938D1 publication Critical patent/DE69906938D1/de
Application granted granted Critical
Publication of DE69906938T2 publication Critical patent/DE69906938T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cosmetics (AREA)
  • Cephalosporin Compounds (AREA)
DE69906938T 1998-02-13 1999-02-15 Glococorticoid selektive entzündungshemmende mittel Expired - Fee Related DE69906938T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/023,913 US6380207B2 (en) 1998-02-13 1998-02-13 Glucocortiocoid-selective antiinflammatory agents
US23913 1998-02-13
PCT/US1999/003210 WO1999041257A1 (en) 1998-02-13 1999-02-15 Glucocorticoid-selective antiinflammatory agents

Publications (2)

Publication Number Publication Date
DE69906938D1 true DE69906938D1 (de) 2003-05-22
DE69906938T2 DE69906938T2 (de) 2004-02-26

Family

ID=21817891

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69906938T Expired - Fee Related DE69906938T2 (de) 1998-02-13 1999-02-15 Glococorticoid selektive entzündungshemmende mittel

Country Status (24)

Country Link
US (1) US6380207B2 (de)
EP (1) EP1053240B1 (de)
JP (1) JP2002503666A (de)
KR (1) KR20010040940A (de)
CN (1) CN1153771C (de)
AT (1) ATE237620T1 (de)
AU (1) AU760511B2 (de)
BG (1) BG64213B1 (de)
BR (1) BR9907847A (de)
CA (1) CA2320911A1 (de)
DE (1) DE69906938T2 (de)
DK (1) DK1053240T3 (de)
ES (1) ES2197618T3 (de)
HK (1) HK1033309A1 (de)
HU (1) HUP0100846A3 (de)
IL (1) IL137509A0 (de)
NO (1) NO20004052L (de)
NZ (1) NZ506012A (de)
PL (1) PL342999A1 (de)
PT (1) PT1053240E (de)
SK (1) SK284076B6 (de)
TR (1) TR200002345T2 (de)
WO (1) WO1999041257A1 (de)
ZA (1) ZA99533B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566372B1 (en) * 1999-08-27 2003-05-20 Ligand Pharmaceuticals Incorporated Bicyclic androgen and progesterone receptor modulator compounds and methods
EP1201660B1 (de) 2000-10-30 2005-08-31 Pfizer Products Inc. Glucocorticoid Rezeptor Modulatoren
US7026484B2 (en) * 2001-02-23 2006-04-11 Ligand Pharmaceuticals Incorporated Tricyclic androgen receptor modulator compounds and methods
AU2003214879B2 (en) 2002-01-22 2008-02-07 The Regents Of The University Of California Non-steroidal ligands for the glucocorticoid receptor, compositions and uses thereof
KR100492913B1 (ko) * 2002-08-23 2005-06-03 주식회사 태평양 피부 감작 및 자극을 완화하는 피부 외용제 조성물
KR20050057086A (ko) 2002-08-28 2005-06-16 홀리스-에덴 파마슈티칼즈, 인코포레이티드 치료적 처치 방법
US20040220153A1 (en) * 2002-09-24 2004-11-04 Jost-Price Edward Roydon Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
CA2501833A1 (en) * 2002-10-11 2004-04-22 Ligand Pharmaceuticals Incorporated 5-(1',1'-cycloalkyl/alkenyl)methylidene 1,2-dihydro-5h-chromeno[3,4-f]quinolines as selective progesterone receptor modulator compounds
DE20301728U1 (de) * 2002-10-11 2004-03-11 Ligand Pharmaceuticals, Inc., San Diego 5-substituierte 7,9-Difluor-5H-Chromeno(3,4-f) -Chinolin-Verbindungen als selektive Progesteronrezeptormodulator-Verbindungen
HK1055058A2 (en) * 2002-10-11 2003-12-05 Ligand Pharm Inc 5-CYCLOALKENYL 5H-CHROMENO[3,4-f]QUINOLINE DERIVATIVES AS SELECTIVE PROGESTERONE RECEPTOR MODULATOR COMPOUNDS
US7235662B2 (en) * 2003-06-11 2007-06-26 Bristol-Myers Squibb Company Modulators of the glucocorticoid receptor and method
BRPI0413820A (pt) 2003-08-22 2006-10-24 Ligand Pharm Inc derivados de 6-cicloamino-2-quinolinona como compostos moduladores de receptor de androgênio
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
DE602004031356D1 (de) 2003-11-21 2011-03-24 Zalicus Inc Verfahren und reagenzien zur behandlung von entzündlichen erkrankungen
WO2005090282A1 (en) 2004-03-12 2005-09-29 Ligand Pharmaceuticals Incorporated Androgen receptor modulator compounds and methods
EP1891067B1 (de) * 2005-06-17 2016-01-13 Ligand Pharmaceuticals Incorporated Androgenrezeptormodulatorverbindungen und verfahren
AU2006282767A1 (en) 2005-08-26 2007-03-01 The Regents Of The University Of California Non-steroidal antiandrogens
NZ568694A (en) 2005-11-09 2011-09-30 Zalicus Inc Method, compositions, and kits for the treatment of medical conditions
CN101326169B (zh) * 2005-12-09 2011-11-16 霍夫曼-拉罗奇有限公司 作为抗炎剂的糖皮质激素受体调节剂
EP1960351B1 (de) * 2005-12-09 2013-06-19 F.Hoffmann-La Roche Ag Propionamidverbindungen als entzündungshemmende mittel
WO2010021681A2 (en) * 2008-08-18 2010-02-25 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
US9908182B2 (en) 2012-01-30 2018-03-06 Black & Decker Inc. Remote programming of a power tool
US8919456B2 (en) 2012-06-08 2014-12-30 Black & Decker Inc. Fastener setting algorithm for drill driver
US10011006B2 (en) 2013-08-08 2018-07-03 Black & Decker Inc. Fastener setting algorithm for drill driver

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693646A (en) 1994-12-22 1997-12-02 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
NZ300739A (en) 1994-12-22 2000-05-26 Ligand Pharm Inc Steroid receptor modulator compounds
US5693133A (en) 1995-05-10 1997-12-02 Akzo Nobel Nv Asbestos free roof coatings

Also Published As

Publication number Publication date
ZA99533B (en) 1999-07-26
NZ506012A (en) 2003-03-28
TR200002345T2 (tr) 2000-11-21
BR9907847A (pt) 2001-01-09
US20010049377A1 (en) 2001-12-06
US6380207B2 (en) 2002-04-30
PL342999A1 (en) 2001-07-16
ES2197618T3 (es) 2004-01-01
CN1297451A (zh) 2001-05-30
SK11962000A3 (sk) 2001-03-12
AU2600399A (en) 1999-08-30
CN1153771C (zh) 2004-06-16
PT1053240E (pt) 2003-09-30
HUP0100846A3 (en) 2003-03-28
SK284076B6 (sk) 2004-09-08
CA2320911A1 (en) 1999-08-19
ATE237620T1 (de) 2003-05-15
DK1053240T3 (da) 2003-08-11
AU760511B2 (en) 2003-05-15
EP1053240A1 (de) 2000-11-22
HUP0100846A2 (hu) 2001-09-28
BG64213B1 (bg) 2004-05-31
IL137509A0 (en) 2001-07-24
NO20004052L (no) 2000-10-12
JP2002503666A (ja) 2002-02-05
HK1033309A1 (en) 2001-08-24
DE69906938T2 (de) 2004-02-26
KR20010040940A (ko) 2001-05-15
EP1053240B1 (de) 2003-04-16
NO20004052D0 (no) 2000-08-11
WO1999041257A1 (en) 1999-08-19
BG104698A (en) 2001-05-31

Similar Documents

Publication Publication Date Title
DE69904804T2 (de) Glucocorticoid selektive entzündungshemmende mittel
DE69906938D1 (de) Glococorticoid selektive entzündungshemmende mittel
WO2002002565A3 (en) Glucocortiocoid-selective antiinflammatory agents
ATE310011T1 (de) Inhibitoren des interleukin-1-beta konvertierenden enzyms
DK0915898T3 (da) Krystalform I af clarithromycin
AU2085201A (en) Compositions and methods for diagnosing and treating conditions, disorders, or diseases involving cell death
BR9811099A (pt) Inibidores de urocinase
DK1039912T3 (da) Angiostatiske midler og præparater til behandling af GLC1A-glaukom
DE69925508D1 (de) Zelladhäsion- und entzündungshemmende immunosuppressive verbindungen
ATE272628T1 (de) Substituierte gamma-phenyl-delta-lactone und deren analoge, und ihre verwendungen
DE60009888D1 (de) Substituierte 3-cyano-[1.7], [1.5] und [1.8]naphthyridininhibitoren von tyrosin kinasen
DE69937301D1 (de) Aminosterolderivate und ihre verwendungen
DE69920717D1 (de) Glucocorticoid selektive entzündungshemmende mittel
PT1107793E (pt) Conjugados de dextrano-leptina, composicoes farmaceuticas e processos relacionados
IL144199A0 (en) Novel bretylium compositions and kits, and their use in preventing and treating cardiovascular conditions
NZ505085A (en) Pharmaceutical compositions comprising bipapcitide monocarboxylate and/or bipapcitide dicarboxylate for imaging and treating thrombi
AU7150598A (en) Methods and compositions for the prevention and treatment of immunological disorders, inflammatory diseases and infections

Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee