ZA99533B - Glucocortiocoid-selective antiinflammatory agents. - Google Patents

Glucocortiocoid-selective antiinflammatory agents.

Info

Publication number
ZA99533B
ZA99533B ZA9900533A ZA99533A ZA99533B ZA 99533 B ZA99533 B ZA 99533B ZA 9900533 A ZA9900533 A ZA 9900533A ZA 99533 A ZA99533 A ZA 99533A ZA 99533 B ZA99533 B ZA 99533B
Authority
ZA
South Africa
Prior art keywords
glucocortiocoid
mammal
antiinflammatory agents
compounds
formula
Prior art date
Application number
ZA9900533A
Other languages
English (en)
Inventor
Michael J Coghlan
Michael E Kort
James P Edwards
Todd K Jones
Original Assignee
Abbott Lab
Ligand Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab, Ligand Pharm Inc filed Critical Abbott Lab
Publication of ZA99533B publication Critical patent/ZA99533B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cosmetics (AREA)
ZA9900533A 1998-02-13 1999-01-25 Glucocortiocoid-selective antiinflammatory agents. ZA99533B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/023,913 US6380207B2 (en) 1998-02-13 1998-02-13 Glucocortiocoid-selective antiinflammatory agents

Publications (1)

Publication Number Publication Date
ZA99533B true ZA99533B (en) 1999-07-26

Family

ID=21817891

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9900533A ZA99533B (en) 1998-02-13 1999-01-25 Glucocortiocoid-selective antiinflammatory agents.

Country Status (24)

Country Link
US (1) US6380207B2 (xx)
EP (1) EP1053240B1 (xx)
JP (1) JP2002503666A (xx)
KR (1) KR20010040940A (xx)
CN (1) CN1153771C (xx)
AT (1) ATE237620T1 (xx)
AU (1) AU760511B2 (xx)
BG (1) BG64213B1 (xx)
BR (1) BR9907847A (xx)
CA (1) CA2320911A1 (xx)
DE (1) DE69906938T2 (xx)
DK (1) DK1053240T3 (xx)
ES (1) ES2197618T3 (xx)
HK (1) HK1033309A1 (xx)
HU (1) HUP0100846A3 (xx)
IL (1) IL137509A0 (xx)
NO (1) NO20004052L (xx)
NZ (1) NZ506012A (xx)
PL (1) PL342999A1 (xx)
PT (1) PT1053240E (xx)
SK (1) SK284076B6 (xx)
TR (1) TR200002345T2 (xx)
WO (1) WO1999041257A1 (xx)
ZA (1) ZA99533B (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566372B1 (en) * 1999-08-27 2003-05-20 Ligand Pharmaceuticals Incorporated Bicyclic androgen and progesterone receptor modulator compounds and methods
DE60113032T2 (de) 2000-10-30 2006-07-06 Pfizer Products Inc., Groton Glukokortikoidrezeptor-Modulatoren
US7026484B2 (en) * 2001-02-23 2006-04-11 Ligand Pharmaceuticals Incorporated Tricyclic androgen receptor modulator compounds and methods
CA2473886C (en) 2002-01-22 2012-08-21 The Regents Of The University Of California Non-steroidal ligands for the glucocorticoid receptor, compositions and uses thereof
KR100492913B1 (ko) * 2002-08-23 2005-06-03 주식회사 태평양 피부 감작 및 자극을 완화하는 피부 외용제 조성물
EP2298316A1 (en) 2002-08-28 2011-03-23 Harbor BioSciences, Inc. Therapeutic treatment methods
US20040220153A1 (en) * 2002-09-24 2004-11-04 Jost-Price Edward Roydon Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
JP2006508076A (ja) * 2002-10-11 2006-03-09 リガンド・ファーマシューティカルズ・インコーポレイテッド 選択的プロゲステロン受容体モジュレーター化合物としての５−シクロアルケニル５Ｈ−クロメノ［３，４−ｆ］キノリン誘導体
DE20301728U1 (de) * 2002-10-11 2004-03-11 Ligand Pharmaceuticals, Inc., San Diego 5-substituierte 7,9-Difluor-5H-Chromeno(3,4-f) -Chinolin-Verbindungen als selektive Progesteronrezeptormodulator-Verbindungen
JP2006504736A (ja) * 2002-10-11 2006-02-09 リガンド・ファーマシューティカルズ・インコーポレイテッド 選択的プロゲステロンレセプター調節化合物としての５−（１’，１’−シクロアルキル／アルケニル）メチリデン１，２−ジヒドロ−５Ｈ−クロメノ［３，４−ｆ］キノリン
US7235662B2 (en) * 2003-06-11 2007-06-26 Bristol-Myers Squibb Company Modulators of the glucocorticoid receptor and method
BRPI0413820A (pt) * 2003-08-22 2006-10-24 Ligand Pharm Inc derivados de 6-cicloamino-2-quinolinona como compostos moduladores de receptor de androgênio
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
JP2007512337A (ja) 2003-11-21 2007-05-17 コンビナトアールエックス インコーポレーティッド 炎症性障害の治療のための方法および試薬
US8519158B2 (en) 2004-03-12 2013-08-27 Ligand Pharmaceuticals Incorporated Androgen receptor modulator compounds and methods
KR101293935B1 (ko) * 2005-06-17 2013-08-08 리간드 파마슈티칼스 인코포레이티드 안드로겐 수용체 조절 화합물 및 방법
EP1916896A4 (en) 2005-08-26 2010-08-11 Univ California NOT STEROID-antiandrogens
EP2218442A1 (en) 2005-11-09 2010-08-18 CombinatoRx, Inc. Methods, compositions, and kits for the treatment of ophthalmic disorders
CN101326155B (zh) * 2005-12-09 2012-06-20 霍夫曼-拉罗奇有限公司 作为抗炎剂的丙酰胺化合物
KR101023001B1 (ko) * 2005-12-09 2011-03-22 에프. 호프만-라 로슈 아게 항염증제로서의 글루코코티코이드 수용체 조절제
WO2010021681A2 (en) * 2008-08-18 2010-02-25 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
US9908182B2 (en) 2012-01-30 2018-03-06 Black & Decker Inc. Remote programming of a power tool
US8919456B2 (en) 2012-06-08 2014-12-30 Black & Decker Inc. Fastener setting algorithm for drill driver
US10011006B2 (en) 2013-08-08 2018-07-03 Black & Decker Inc. Fastener setting algorithm for drill driver

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693646A (en) 1994-12-22 1997-12-02 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
EP1043326A1 (en) 1994-12-22 2000-10-11 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
US5693133A (en) 1995-05-10 1997-12-02 Akzo Nobel Nv Asbestos free roof coatings

Also Published As

Publication number Publication date
SK11962000A3 (sk) 2001-03-12
DK1053240T3 (da) 2003-08-11
DE69906938T2 (de) 2004-02-26
NZ506012A (en) 2003-03-28
SK284076B6 (sk) 2004-09-08
EP1053240B1 (en) 2003-04-16
BG64213B1 (bg) 2004-05-31
PL342999A1 (en) 2001-07-16
EP1053240A1 (en) 2000-11-22
CA2320911A1 (en) 1999-08-19
NO20004052D0 (no) 2000-08-11
US20010049377A1 (en) 2001-12-06
US6380207B2 (en) 2002-04-30
HK1033309A1 (en) 2001-08-24
HUP0100846A2 (hu) 2001-09-28
CN1153771C (zh) 2004-06-16
DE69906938D1 (de) 2003-05-22
CN1297451A (zh) 2001-05-30
BR9907847A (pt) 2001-01-09
JP2002503666A (ja) 2002-02-05
PT1053240E (pt) 2003-09-30
WO1999041257A1 (en) 1999-08-19
ES2197618T3 (es) 2004-01-01
NO20004052L (no) 2000-10-12
BG104698A (en) 2001-05-31
TR200002345T2 (tr) 2000-11-21
HUP0100846A3 (en) 2003-03-28
AU2600399A (en) 1999-08-30
KR20010040940A (ko) 2001-05-15
AU760511B2 (en) 2003-05-15
ATE237620T1 (de) 2003-05-15
IL137509A0 (en) 2001-07-24

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