BG63539B1 - Подобрен метод за получаване на r(+)1,2,3,6-тетрахидро-4- фенил-1-[(3-фенил-3-циклохексен-1-ил)метил]пиридин - Google Patents
Подобрен метод за получаване на r(+)1,2,3,6-тетрахидро-4- фенил-1-[(3-фенил-3-циклохексен-1-ил)метил]пиридин Download PDFInfo
- Publication number
- BG63539B1 BG63539B1 BG101271A BG10127197A BG63539B1 BG 63539 B1 BG63539 B1 BG 63539B1 BG 101271 A BG101271 A BG 101271A BG 10127197 A BG10127197 A BG 10127197A BG 63539 B1 BG63539 B1 BG 63539B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- formula
- compound
- solvent
- give
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/304,074 US5710277A (en) | 1994-09-12 | 1994-09-12 | Process for R (+) 1,2,3,6-tetrahydro-4-phenyl-1- (3-phenyl-3-cyclohexen-1-yl)methyl!pyridine, a central nervous system agent |
PCT/US1995/009511 WO1996008473A1 (en) | 1994-09-12 | 1995-07-28 | Improved process for r (+) 1,2,3,6-tetrahydro-4-phenyl-1-[(3-phenyl-3-cyclohexen-1-yl)methyl]pyridine, a central nervous system agent |
Publications (2)
Publication Number | Publication Date |
---|---|
BG101271A BG101271A (en) | 1998-03-31 |
BG63539B1 true BG63539B1 (bg) | 2002-04-30 |
Family
ID=23174951
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG101271A BG63539B1 (bg) | 1994-09-12 | 1997-02-27 | Подобрен метод за получаване на r(+)1,2,3,6-тетрахидро-4- фенил-1-[(3-фенил-3-циклохексен-1-ил)метил]пиридин |
Country Status (18)
Country | Link |
---|---|
US (1) | US5710277A (ja) |
EP (1) | EP0781274A1 (ja) |
JP (1) | JPH10505610A (ja) |
KR (1) | KR100379069B1 (ja) |
BG (1) | BG63539B1 (ja) |
CA (1) | CA2194000A1 (ja) |
CZ (1) | CZ288258B6 (ja) |
HR (1) | HRP950471A2 (ja) |
HU (1) | HU219244B (ja) |
MD (1) | MD1787G2 (ja) |
MX (1) | MX9700331A (ja) |
NO (2) | NO307881B1 (ja) |
NZ (1) | NZ290701A (ja) |
PL (2) | PL184075B1 (ja) |
RU (1) | RU2144026C1 (ja) |
TJ (1) | TJ257B (ja) |
WO (1) | WO1996008473A1 (ja) |
ZA (1) | ZA957615B (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6362301B1 (en) * | 1994-06-13 | 2002-03-26 | Rohm And Haas Company | Curable composition |
US6433098B1 (en) | 1994-06-13 | 2002-08-13 | Rohm And Haas Company | Process of preparing curable compositions and compositions therefrom |
CN115572224A (zh) * | 2021-06-21 | 2023-01-06 | 上海茂晟康慧科技有限公司 | 一种(s)-(-)-3-环己烯甲酸的合成方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1189982A (fr) * | 1957-10-10 | 1959-10-08 | Centre Nat Rech Scient | Procédé de préparation de cycloheptadiènones-2-4 substituées |
US5314896A (en) * | 1991-11-20 | 1994-05-24 | Warner-Lambert Company | 1,3-substituted cycloalkenes and cycloalkanes as central nervous system agents |
-
1994
- 1994-09-12 US US08/304,074 patent/US5710277A/en not_active Expired - Fee Related
-
1995
- 1995-07-28 PL PL95347274A patent/PL184075B1/pl unknown
- 1995-07-28 KR KR1019970701595A patent/KR100379069B1/ko not_active IP Right Cessation
- 1995-07-28 CZ CZ1997740A patent/CZ288258B6/cs not_active IP Right Cessation
- 1995-07-28 TJ TJ97000456A patent/TJ257B/xx unknown
- 1995-07-28 EP EP95927500A patent/EP0781274A1/en not_active Withdrawn
- 1995-07-28 PL PL95319076A patent/PL184241B1/pl not_active IP Right Cessation
- 1995-07-28 JP JP8510175A patent/JPH10505610A/ja not_active Ceased
- 1995-07-28 WO PCT/US1995/009511 patent/WO1996008473A1/en active IP Right Grant
- 1995-07-28 HU HU9702120A patent/HU219244B/hu not_active IP Right Cessation
- 1995-07-28 MX MX9700331A patent/MX9700331A/es not_active IP Right Cessation
- 1995-07-28 NZ NZ290701A patent/NZ290701A/en unknown
- 1995-07-28 CA CA002194000A patent/CA2194000A1/en not_active Abandoned
- 1995-07-28 MD MD97-0146A patent/MD1787G2/ro unknown
- 1995-07-28 RU RU97105760/04A patent/RU2144026C1/ru not_active IP Right Cessation
- 1995-09-11 ZA ZA957615A patent/ZA957615B/xx unknown
- 1995-09-12 HR HR08/304,074A patent/HRP950471A2/hr not_active Application Discontinuation
-
1997
- 1997-02-27 BG BG101271A patent/BG63539B1/bg unknown
- 1997-03-11 NO NO971122A patent/NO307881B1/no not_active IP Right Cessation
-
1999
- 1999-11-19 NO NO995678A patent/NO309084B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PL319076A1 (en) | 1997-07-21 |
NO309084B1 (no) | 2000-12-11 |
NZ290701A (en) | 1998-04-27 |
US5710277A (en) | 1998-01-20 |
CZ74097A3 (en) | 1997-12-17 |
TJ257B (en) | 2000-05-12 |
WO1996008473A1 (en) | 1996-03-21 |
JPH10505610A (ja) | 1998-06-02 |
HUT77531A (hu) | 1998-05-28 |
RU2144026C1 (ru) | 2000-01-10 |
MD1787G2 (ro) | 2002-05-31 |
MD1787F2 (en) | 2001-11-30 |
NO995678D0 (no) | 1999-11-19 |
ZA957615B (en) | 1996-04-22 |
PL184241B1 (pl) | 2002-09-30 |
MX9700331A (es) | 1997-05-31 |
NO971122L (no) | 1997-03-11 |
NO307881B1 (no) | 2000-06-13 |
MD970146A (en) | 1999-02-28 |
NO971122D0 (no) | 1997-03-11 |
BG101271A (en) | 1998-03-31 |
EP0781274A1 (en) | 1997-07-02 |
HU219244B (en) | 2001-03-28 |
KR100379069B1 (ko) | 2003-07-23 |
PL184075B1 (pl) | 2002-08-30 |
NO995678L (no) | 1997-03-11 |
HRP950471A2 (en) | 1997-08-31 |
CA2194000A1 (en) | 1996-03-21 |
AU3151595A (en) | 1996-03-29 |
AU697702B2 (en) | 1998-10-15 |
CZ288258B6 (en) | 2001-05-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR101119309B1 (ko) | (3,4?디메톡시?바이시클로〔4.2.0〕옥타?1,3,5?트리엔?7?일)니트릴의 거울상이성질체의 분리 방법 및 이바브라딘의 합성에서의 적용 | |
WO2018210336A1 (zh) | Glyx-13的制备方法及其中间体化合物 | |
FI106024B (fi) | Menetelmä fibrinogeenireseptoriantagonisteina käyttökelpoisen N-(n-butyylisulfonyyli)-O-[4-(4 -piperidyyli)butyyli]tyrosiinin ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi | |
US5101040A (en) | Process for the industrial preparation of 4-chloro-3-sulfamoyl-n-(2,3-dihydro-2-methyl-1h-indol-1-yl)benzamide | |
SE448459B (sv) | 4a,9b-trans-hexahydro-gamma-karbolinforeningar som mellanprodukter for framstellning av hexahydro-gamma-karbolinforeningar | |
BG63539B1 (bg) | Подобрен метод за получаване на r(+)1,2,3,6-тетрахидро-4- фенил-1-[(3-фенил-3-циклохексен-1-ил)метил]пиридин | |
US4247704A (en) | Hexahydro thieno imadazole intermediates for the synthesis of biotin | |
EP0389425B1 (de) | Neue Benzothiopyranylamine | |
SU999977A3 (ru) | Способ получени 3,3-этилендиокси-4,5-секо-19-норандрост-9-ен-5,17-диона | |
AU697702C (en) | Improved process for R (+) 1,2,3,6-tetrahydro- 4-phenyl-1-((3-phenyl-3-cyclohexen-1-yl) methyl)pyridine, a central nervous system agent | |
JP2001521498A (ja) | O−(3−アミノ−2−ヒドロキシ−プロピル)−ヒドロキシミック酸ハロゲン化物の製造方法 | |
JP2994220B2 (ja) | ヘキサヒドロアゼピノンおよびヘキサヒドロアゼピノールの製造方法 | |
EP0973737A4 (en) | EFFECTIVE SYNTHESIS OF A CHIRAL MEDIATOR | |
AU724816B2 (en) | Process for the preparation of chiral, nonracemic(4-aryl-2,5-dioxoimidazolidin-1-yl)acetic acids | |
US4284557A (en) | Intermediate racemates for the preparation of biotin and a process for their preparation | |
JPH07278155A (ja) | アミノホウ酸誘導体、その製法およびその合成中間体としての用途 | |
JP2002155058A (ja) | 1位置換ヒダントイン類の製造方法 | |
US4320056A (en) | Certain thia-diazatricyclo[3,3,3,08,11 ]tridecanes, and their preparation | |
US4382031A (en) | Intermediates for the preparation of biotin | |
JPH01197478A (ja) | N―(2―クロロベンジル)―2―(2―チエニル)エチルアミンの製法 | |
CN118206501A (zh) | 一种卢吗哌酮的制备方法 | |
US5986107A (en) | Process for the preparation of a 2-oxopyrrolidine compound | |
CA2148880A1 (fr) | Derives de 5,6-dihydro-4h-thieno[3,4-c]pyrrole, leur preparation et leur application en therapeutique | |
US20040010039A1 (en) | Ethane-1,2-diaminium bis[(2R)-2-bromo-3-phenylpropanoate], processes for its preparation and its use | |
SU1447280A3 (ru) | Способ получени пиридиловых соединений, или их сложного эфира, или амида, или кислотно-аддитивных солей |