BG63367B1 - Нитробензамиди, полезни като противоаритмични средства - Google Patents

Нитробензамиди, полезни като противоаритмични средства Download PDF

Info

Publication number
BG63367B1
BG63367B1 BG101501A BG10150197A BG63367B1 BG 63367 B1 BG63367 B1 BG 63367B1 BG 101501 A BG101501 A BG 101501A BG 10150197 A BG10150197 A BG 10150197A BG 63367 B1 BG63367 B1 BG 63367B1
Authority
BG
Bulgaria
Prior art keywords
formula
compound
pharmaceutically acceptable
compounds
solvate
Prior art date
Application number
BG101501A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG101501A (en
Inventor
Guy Nadler
Michel Martin
Original Assignee
Smithkline Beecham Laboratoires Pharmaceutiques
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Laboratoires Pharmaceutiques filed Critical Smithkline Beecham Laboratoires Pharmaceutiques
Publication of BG101501A publication Critical patent/BG101501A/xx
Publication of BG63367B1 publication Critical patent/BG63367B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/78—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG101501A 1994-10-26 1997-05-20 Нитробензамиди, полезни като противоаритмични средства BG63367B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9412806A FR2726267B1 (fr) 1994-10-26 1994-10-26 Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer
PCT/EP1995/004203 WO1996013479A1 (en) 1994-10-26 1995-10-24 Nitro-benzamides useful as anti-arrhythmic agents

Publications (2)

Publication Number Publication Date
BG101501A BG101501A (en) 1998-01-30
BG63367B1 true BG63367B1 (bg) 2001-11-30

Family

ID=9468229

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101501A BG63367B1 (bg) 1994-10-26 1997-05-20 Нитробензамиди, полезни като противоаритмични средства

Country Status (36)

Country Link
US (3) US5977179A (hu)
EP (1) EP0788474B1 (hu)
JP (1) JPH10508013A (hu)
KR (1) KR100369958B1 (hu)
CN (1) CN1071740C (hu)
AP (1) AP694A (hu)
AT (1) ATE192428T1 (hu)
AU (1) AU697357B2 (hu)
BG (1) BG63367B1 (hu)
BR (1) BR9509432A (hu)
CA (1) CA2203814A1 (hu)
CZ (1) CZ290326B6 (hu)
DE (1) DE69516708T2 (hu)
DK (1) DK0788474T3 (hu)
DZ (1) DZ1937A1 (hu)
ES (1) ES2145306T3 (hu)
FI (1) FI971755A (hu)
FR (1) FR2726267B1 (hu)
GR (1) GR3033748T3 (hu)
HK (1) HK1002764A1 (hu)
HU (1) HU222889B1 (hu)
ID (1) ID18094A (hu)
IL (1) IL115732A (hu)
MA (1) MA23706A1 (hu)
NO (1) NO971955L (hu)
NZ (1) NZ295368A (hu)
OA (1) OA10478A (hu)
PL (1) PL181936B1 (hu)
PT (1) PT788474E (hu)
RO (1) RO117174B1 (hu)
RU (1) RU2159227C2 (hu)
SK (1) SK281743B6 (hu)
TR (1) TR199501320A2 (hu)
UA (1) UA50722C2 (hu)
WO (1) WO1996013479A1 (hu)
ZA (1) ZA958984B (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2726267B1 (fr) 1994-10-26 1998-01-02 Smithkline Beecham Lab Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer
GB9706376D0 (en) * 1997-03-27 1997-05-14 Smithkline Beecham Plc Novel pharmaceutical
GB9923934D0 (en) * 1999-10-08 1999-12-08 Smithkline Beecham Plc Novel pharmaceutical
GB9923933D0 (en) * 1999-10-08 1999-12-08 Smithkline Beecham Lab Novel pharmaceutical
ATE327230T1 (de) 2000-01-20 2006-06-15 Eisai Co Ltd Piperidinverbindungen und diese enthaltenden medikamente
AU2003282464B2 (en) * 2002-10-11 2010-02-25 Baxter International, Inc. Method for cardioprotection and neuroprotection by intravenous administration of halogenated volatile anesthetics
WO2004078715A1 (ja) 2003-03-07 2004-09-16 Astellas Pharma Inc. ２，６－ジ置換スチリルを有する含窒素へテロ環誘導体
RU2700263C1 (ru) * 2019-05-16 2019-09-16 федеральное государственное автономное образовательное учреждение высшего образования «Национальный исследовательский Томский политехнический университет» Средство, обладающее антиаритмическим действием

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE242344C (hu)
US3139456A (en) * 1960-07-27 1964-06-30 Searle & Co Nu-(substituted phenoxyalkyl)-aralkylamines
DE3242344A1 (de) * 1982-11-16 1984-05-17 Dr. Karl Thomae Gmbh, 7950 Biberach Neue alkylendiaminoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
EG18188A (en) * 1986-05-01 1992-09-30 Pfizer Ltd Process for preparation anti-arhythmia agents
GB8706662D0 (en) * 1987-03-20 1987-04-23 Pfizer Ltd Anti-arrhythmia agents
CZ283038B6 (cs) * 1991-01-11 1997-12-17 Laboratoires Glaxo Sa Akridinové deriváty, způsob výroby a farmaceutické prostředky s jejich obsahem
US5208252A (en) * 1992-07-24 1993-05-04 Ortho Pharmaceutical Corporation Aminoethylthiophene derivatives
DE4422517A1 (de) * 1994-06-28 1996-01-04 Dresden Arzneimittel Neue (2-(3,4-Dimethoxy-phenyl)-ethyl)-(2-phenoxy-ethyl)-amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
JP3904599B2 (ja) * 1994-08-04 2007-04-11 シー・アンド・シー・リサーチ・ラブズ 新規なアミン誘導体、その製造方法及び抗不整脈剤としての用途
FR2726267B1 (fr) 1994-10-26 1998-01-02 Smithkline Beecham Lab Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer

Also Published As

Publication number Publication date
IL115732A (en) 2000-08-31
EP0788474B1 (en) 2000-05-03
KR100369958B1 (ko) 2003-04-08
FI971755A0 (fi) 1997-04-24
HUT77004A (hu) 1998-03-02
UA50722C2 (uk) 2002-11-15
RO117174B1 (ro) 2001-11-30
BR9509432A (pt) 1998-01-06
DE69516708T2 (de) 2000-09-28
GR3033748T3 (en) 2000-10-31
CA2203814A1 (en) 1996-05-09
US20010025054A1 (en) 2001-09-27
DE69516708D1 (de) 2000-06-08
AU697357B2 (en) 1998-10-01
MA23706A1 (fr) 1996-07-01
AU3869995A (en) 1996-05-23
FR2726267B1 (fr) 1998-01-02
ATE192428T1 (de) 2000-05-15
US6570037B2 (en) 2003-05-27
AP694A (en) 1998-11-18
SK50597A3 (en) 1997-11-05
EP0788474A1 (en) 1997-08-13
IL115732A0 (en) 1996-05-14
PT788474E (pt) 2000-08-31
NZ295368A (en) 1998-12-23
CZ125297A3 (en) 1997-10-15
HK1002764A1 (en) 1998-09-18
CN1071740C (zh) 2001-09-26
ZA958984B (en) 1997-04-24
ES2145306T3 (es) 2000-07-01
CN1170402A (zh) 1998-01-14
CZ290326B6 (cs) 2002-07-17
AP9700965A0 (en) 1997-04-30
DK0788474T3 (da) 2000-09-11
PL181936B1 (pl) 2001-10-31
RU2159227C2 (ru) 2000-11-20
HU222889B1 (hu) 2003-12-29
BG101501A (en) 1998-01-30
DZ1937A1 (fr) 2002-02-17
ID18094A (id) 1998-02-26
NO971955L (no) 1997-06-25
SK281743B6 (sk) 2001-07-10
MX9703112A (es) 1997-07-31
NO971955D0 (no) 1997-04-25
FR2726267A1 (fr) 1996-05-03
FI971755A (fi) 1997-06-23
PL319904A1 (en) 1997-09-01
OA10478A (en) 2002-04-09
US20020107243A1 (en) 2002-08-08
WO1996013479A1 (en) 1996-05-09
JPH10508013A (ja) 1998-08-04
TR199501320A2 (tr) 1996-06-21
US5977179A (en) 1999-11-02

Similar Documents

Publication Publication Date Title
JPH09501404A (ja) 新規化合物
EP0178874A1 (en) Alkylsulfonamidophenylalkylamines
WO1994027971A1 (en) Anti-arrhythmic n-substituted 3-benzazepines or isoquinolines
BG63367B1 (bg) Нитробензамиди, полезни като противоаритмични средства
FR2729142A1 (fr) Nouvelles amines heterocycliques, leur procede de preparation et leur utilisation en tant que medicaments et notamment en tant qu'agents anti-arythmiques
EP0719263B1 (en) Heterocyclic carboxamide derivatives with antiarrhythmic activity
US5712284A (en) Azalicyclooctane derivatives as anti-arrhythmic agents
US5874475A (en) Antiarrhythmic (S)-enantiomers of methanesulfonamides
MXPA97003112A (en) Nitro-benzamides useful as agentesantiarritmi
WO1996027595A1 (en) Heterocyclycarboxamides and other compounds for the treatment of the cardiac arrhythmias
FR2729144A1 (fr) Nouvelles diamines, leur procede de preparation et leur utilisation en tant que medicaments et notamment en tant qu' agents anti-arythmiques
FR2705674A1 (fr) Nouveaux composés et leur procédé de préparation et leur utilisation en tant que médicaments.
FR2705675A1 (fr) Nouveaux composés, leur procédé de préparation et leur utilisation en tant que médicaments.
WO1995007884A1 (en) Alkanediamine derivatives and their use in the treatment of arrhythmic and ischaemic rhythm disorders
FR2729139A1 (fr) Nouveaux derives d'amine, leur procede de preparation et leur utilisation en tant que medicaments et notamment en tant qu'agents anti-arythmiques
FR2729143A1 (fr) Nouveaux derives d'amine, leur procede de preparation et leur utilisation en tant que medicaments et notamment en tant qu'agents anti-arythmiques
FR2710069A1 (fr) Nouveaux composés, leur procédé de préparation et leur utilisation en tant que médicaments.
FR2729148A1 (fr) Nouveaux derives d'amine, leur procede de preparation et leur utilisation en tant que medicaments et notamment en tant qu'agents anti-arythmiques
FR2729146A1 (fr) Nouveaux derives d'amine, leur procede de preparation et leur utilisation en tant que medicaments et notamment en tant qu'agents anti-arythmiques
FR2707985A1 (fr) Nouveaux composés, leur procédé de préparation et leur utilisation en tant que médicaments.