BG63126B1 - Лечебни препарати на основата на нуклеинови киселини - Google Patents

Лечебни препарати на основата на нуклеинови киселини Download PDF

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Publication number
BG63126B1
BG63126B1 BG100006A BG10000695A BG63126B1 BG 63126 B1 BG63126 B1 BG 63126B1 BG 100006 A BG100006 A BG 100006A BG 10000695 A BG10000695 A BG 10000695A BG 63126 B1 BG63126 B1 BG 63126B1
Authority
BG
Bulgaria
Prior art keywords
seq
dna
gene
influenza
vijns
Prior art date
Application number
BG100006A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG100006A (bg
Inventor
John Donnelly
Varavani Dwarki
Margaret Liu
Donna Montgomery
Suezanne Parker
John SHIVER
Jeffrey Ulmer
Original Assignee
Merck & Co. Inc.
Vical Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. Inc., Vical Incorporated filed Critical Merck & Co. Inc.
Publication of BG100006A publication Critical patent/BG100006A/bg
Publication of BG63126B1 publication Critical patent/BG63126B1/bg

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
BG100006A 1993-03-18 1995-09-18 Лечебни препарати на основата на нуклеинови киселини BG63126B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3238393A 1993-03-18 1993-03-18
US8998593A 1993-07-08 1993-07-08
PCT/US1994/002751 WO1994021797A1 (fr) 1993-03-18 1994-03-14 Produits pharmaceutiques d'acide nucleique

Publications (2)

Publication Number Publication Date
BG100006A BG100006A (bg) 1996-12-31
BG63126B1 true BG63126B1 (bg) 2001-04-30

Family

ID=26708344

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100006A BG63126B1 (bg) 1993-03-18 1995-09-18 Лечебни препарати на основата на нуклеинови киселини

Country Status (22)

Country Link
EP (1) EP0620277A1 (fr)
JP (2) JP2812352B2 (fr)
CN (1) CN1119458A (fr)
AU (1) AU676258B2 (fr)
BG (1) BG63126B1 (fr)
BR (1) BR9406007A (fr)
CA (1) CA2119175A1 (fr)
CZ (1) CZ290315B6 (fr)
DZ (1) DZ1759A1 (fr)
FI (1) FI954329A0 (fr)
HR (1) HRP940175A2 (fr)
HU (1) HUT73397A (fr)
IL (1) IL108915A0 (fr)
NO (1) NO953649L (fr)
NZ (1) NZ263680A (fr)
PL (1) PL178626B1 (fr)
RO (1) RO117710B1 (fr)
SI (1) SI9420014A (fr)
SK (1) SK114295A3 (fr)
UA (1) UA42715C2 (fr)
WO (1) WO1994021797A1 (fr)
YU (1) YU12894A (fr)

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US6019980A (en) 1995-06-07 2000-02-01 Connaught Laboratories Limited Nucleic acid respiratory syncytial virus vaccines
US6017897A (en) * 1995-06-07 2000-01-25 Pasteur Merieux Connaught Canada Nucleic acid respiratory syncytial virus vaccines
US6537776B1 (en) 1999-06-14 2003-03-25 Diversa Corporation Synthetic ligation reassembly in directed evolution
FR2751225B1 (fr) * 1996-07-19 1998-11-27 Rhone Merieux Formule de vaccin polynucleotidique aviaire
US6204250B1 (en) 1996-11-22 2001-03-20 The Mount Sinai Medical Center Of The City Of New York Immunization of infants
AU722326B2 (en) * 1997-02-14 2000-07-27 Merck & Co., Inc. Polynucleotide vaccine formulations
US6517843B1 (en) 1999-08-31 2003-02-11 Merial Reduction of porcine circovirus-2 viral load with inactivated PCV-2
UA78180C2 (uk) 1997-10-03 2007-03-15 Меріаль Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
US6686339B1 (en) 1998-08-20 2004-02-03 Aventis Pasteur Limited Nucleic acid molecules encoding inclusion membrane protein C of Chlamydia
US6693087B1 (en) 1998-08-20 2004-02-17 Aventis Pasteur Limited Nucleic acid molecules encoding POMP91A protein of Chlamydia
EP1105490A1 (fr) 1998-08-20 2001-06-13 Aventis Pasteur Limited Molecules d'acide nucleique codant la proteine membrane d'inclusion c de chlamydia
US6881723B1 (en) 1998-11-05 2005-04-19 Powderject Vaccines, Inc. Nucleic acid constructs
US7691389B2 (en) 1998-12-22 2010-04-06 Pfizer Inc Infectious cDNA clone of north american porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
US7618797B2 (en) 1998-12-22 2009-11-17 Pfizer Inc Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
AU3593200A (en) 1999-02-09 2000-08-29 Powderject Vaccines, Inc. (mycobacterium tuberculosis), immunization
US6943152B1 (en) 1999-06-10 2005-09-13 Merial DNA vaccine-PCV
JP2001151698A (ja) * 1999-09-10 2001-06-05 Nichiko Pharmaceutical Co Ltd インフルエンザワクチン
AU1013601A (en) 1999-10-22 2001-05-08 Aventis Pasteur Limited Method of inducing and/or enhancing an immune response to tumor antigens
US7196066B1 (en) 1999-11-03 2007-03-27 Powderject Vaccines, Inc. DNA-vaccines based on constructs derived from the genomes of human and animal pathogens
US6852705B2 (en) 2000-01-21 2005-02-08 Merial DNA vaccines for farm animals, in particular bovines and porcines
US7078388B2 (en) 2000-01-21 2006-07-18 Merial DNA vaccines for farm animals, in particular bovines and porcines
EP1792995A3 (fr) 2000-05-08 2007-06-13 Sanofi Pasteur Limited Antigènes de chlamydia et fragments d'adn correspondants, et utilisations de ceux-ci
CA2408328C (fr) 2000-05-10 2012-04-17 Aventis Pasteur Limited Polypeptides immunogeniques codes par des minigenes mage et leurs utilisations
AU2005248361B2 (en) 2004-05-18 2010-03-11 Vical Incorporated Influenza virus vaccine composition and methods of use
US8202967B2 (en) 2006-10-27 2012-06-19 Boehringer Ingelheim Vetmedica, Inc. H5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use
CA2687888A1 (fr) * 2007-05-31 2008-12-11 Becton, Dickinson And Company Sequences et procedes de detection du virus de la grippe a et du virus de la grippe b
US8354230B2 (en) * 2007-12-21 2013-01-15 Quest Diagnostics Investments Inc. Multiplex detection assay for influenza and RSV viruses
EP2318044B1 (fr) 2008-08-01 2015-12-02 Gamma Vaccines Pty Limited Vaccins contre la grippe
US8894997B2 (en) 2009-04-30 2014-11-25 Vanderbilt University Monoclonal antibodies to influenza H1N1 virus uses thereof
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TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低pcv-2組合物殺病毒活性之方法及具有改良免疫原性之pcv-2組合物
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AR088028A1 (es) 2011-08-15 2014-05-07 Boehringer Ingelheim Vetmed Proteinas h5, de h5n1 para un uso medicinal
WO2013033092A2 (fr) 2011-09-03 2013-03-07 Boehringer Ingelheim Vetmedica Gmbh Antigènes de poil de streptococcus suis
US10383835B2 (en) 2012-03-14 2019-08-20 The Regents Of The University Of California Treatment of inflammatory disorders in non-human mammals
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KR102379951B1 (ko) * 2013-03-18 2022-03-31 오시벡스 에스에이에스 인플루엔자 핵단백질 백신
US9987348B2 (en) 2013-09-25 2018-06-05 Zoetis Services Llc PCV2B divergent vaccine composition and methods of use
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BR112017028224A2 (pt) 2015-08-31 2018-09-11 Boehringer Ingelheim Vetmedica Gmbh composição, e, método para proteger um leitão contra uma doença associada a pestivírus.
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CN109715219B (zh) 2016-09-20 2024-03-01 勃林格殷格翰动物保健有限公司 犬腺病毒载体
EP3515480A1 (fr) 2016-09-20 2019-07-31 Boehringer Ingelheim Vetmedica GmbH Nouveau vaccin contre la grippe porcine
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CA3036293A1 (fr) 2016-09-20 2018-03-29 Boehringer Ingelheim Vetmedica Gmbh Nouveaux promoteurs
MX2019005136A (es) 2016-11-03 2019-06-20 Boehringer Ingelheim Vetmedica Gmbh Vacuna contra el parvovirus porcino y el virus del sindrome respiratorio reproductivo porcino y metodos de produccion de esta.
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Also Published As

Publication number Publication date
UA42715C2 (uk) 2001-11-15
BR9406007A (pt) 1996-01-02
SK114295A3 (en) 1996-02-07
WO1994021797A1 (fr) 1994-09-29
JPH0795888A (ja) 1995-04-11
RO117710B1 (ro) 2002-06-28
EP0620277A1 (fr) 1994-10-19
NO953649D0 (no) 1995-09-15
HUT73397A (en) 1996-07-29
FI954329A (fi) 1995-09-14
NO953649L (no) 1995-11-17
CN1119458A (zh) 1996-03-27
SI9420014A (en) 1996-08-31
AU676258B2 (en) 1997-03-06
HU9502702D0 (en) 1995-11-28
JPH10113194A (ja) 1998-05-06
JP2812352B2 (ja) 1998-10-22
CZ237395A3 (en) 1996-02-14
IL108915A0 (en) 1994-06-24
BG100006A (bg) 1996-12-31
PL178626B1 (pl) 2000-05-31
YU12894A (sh) 1997-12-05
PL310677A1 (en) 1995-12-27
AU5788994A (en) 1994-09-22
DZ1759A1 (fr) 2002-02-17
JP3608642B2 (ja) 2005-01-12
CZ290315B6 (cs) 2002-07-17
FI954329A0 (fi) 1995-09-14
HRP940175A2 (en) 1997-04-30
CA2119175A1 (fr) 1994-09-19
NZ263680A (en) 1997-05-26

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