BG62618B1 - Асиметрично заместени ксантини с аденозинантагонистичнисвойства, метод за тяхното получаване и междинни съединения затази цел, приложение на тези съединения като фармакологичнисредства, фармацевтични смеси, които ги съдържат, и метод затяхното получаване - Google Patents

Асиметрично заместени ксантини с аденозинантагонистичнисвойства, метод за тяхното получаване и междинни съединения затази цел, приложение на тези съединения като фармакологичнисредства, фармацевтични смеси, които ги съдържат, и метод затяхното получаване Download PDF

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Publication number
BG62618B1
BG62618B1 BG99489A BG9948995A BG62618B1 BG 62618 B1 BG62618 B1 BG 62618B1 BG 99489 A BG99489 A BG 99489A BG 9948995 A BG9948995 A BG 9948995A BG 62618 B1 BG62618 B1 BG 62618B1
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BG
Bulgaria
Prior art keywords
och
conr
radical
substituted
general formula
Prior art date
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BG99489A
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Bulgarian (bg)
English (en)
Other versions
BG99489A (bg
Inventor
Ulrike Kuefner-Muehl
Helmut Ensinger
Joachim Mierau
Franz J. Kuhn
Erich Lehr
Enzio Mueller
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of BG99489A publication Critical patent/BG99489A/bg
Publication of BG62618B1 publication Critical patent/BG62618B1/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG99489A 1992-08-10 1995-03-09 Асиметрично заместени ксантини с аденозинантагонистичнисвойства, метод за тяхното получаване и междинни съединения затази цел, приложение на тези съединения като фармакологичнисредства, фармацевтични смеси, които ги съдържат, и метод затяхното получаване BG62618B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4226371 1992-08-10
DE4238423 1992-11-13
PCT/EP1993/002077 WO1994003456A1 (de) 1992-08-10 1993-08-05 Unsymmetrisch substituierte xanthine mit adenosinantagonistischen eigenschaften

Publications (2)

Publication Number Publication Date
BG99489A BG99489A (bg) 1996-01-31
BG62618B1 true BG62618B1 (bg) 2000-03-31

Family

ID=25917371

Family Applications (1)

Application Number Title Priority Date Filing Date
BG99489A BG62618B1 (bg) 1992-08-10 1995-03-09 Асиметрично заместени ксантини с аденозинантагонистичнисвойства, метод за тяхното получаване и междинни съединения затази цел, приложение на тези съединения като фармакологичнисредства, фармацевтични смеси, които ги съдържат, и метод затяхното получаване

Country Status (21)

Country Link
US (1) US5719279A (ar)
EP (1) EP0654033A1 (ar)
JP (1) JPH08500344A (ar)
KR (1) KR950702988A (ar)
CN (1) CN1043348C (ar)
AU (1) AU681348B2 (ar)
BG (1) BG62618B1 (ar)
CA (1) CA2140883A1 (ar)
CZ (1) CZ286459B6 (ar)
FI (1) FI950542A (ar)
HU (1) HUT65734A (ar)
IL (1) IL106624A (ar)
MX (1) MX9304819A (ar)
NZ (1) NZ254804A (ar)
PL (1) PL176389B1 (ar)
RU (1) RU2138500C1 (ar)
SG (1) SG55038A1 (ar)
SK (1) SK18595A3 (ar)
TW (1) TW252044B (ar)
UA (1) UA46697C2 (ar)
WO (1) WO1994003456A1 (ar)

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US6248746B1 (en) 1998-01-07 2001-06-19 Euro-Celtique S.A. 3-(arylalkyl) xanthines
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JP5769966B2 (ja) * 2007-08-17 2015-08-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｆａｂ関連疾患治療用プリン誘導体
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ES2950384T3 (es) 2014-02-28 2023-10-09 Boehringer Ingelheim Int Uso médico de un inhibidor de DPP-4
CN109310697A (zh) 2016-06-10 2019-02-05 勃林格殷格翰国际有限公司 利格列汀和二甲双胍的组合
RU2643336C1 (ru) * 2016-10-03 2018-01-31 Общество с Ограниченной Ответственностью "Компания "ЭЛТА" СРЕДСТВО, ПРОЯВЛЯЮЩЕЕ АНТИТРОМБОТИЧЕСКИЙ ЭФФЕКТ ПОСРЕДСТВОМ БЛОКИРОВАНИЯ РЕЦЕПТОРОВ ТРОМБОЦИТОВ ГП IIb-IIIa (ВАРИАНТЫ)
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Also Published As

Publication number Publication date
FI950542A0 (fi) 1995-02-08
CZ286459B6 (en) 2000-04-12
JPH08500344A (ja) 1996-01-16
BG99489A (bg) 1996-01-31
SK18595A3 (en) 1995-07-11
HU9302302D0 (en) 1993-10-28
CZ34895A3 (en) 1995-10-18
RU2138500C1 (ru) 1999-09-27
UA46697C2 (uk) 2002-06-17
PL307397A1 (en) 1995-05-15
PL176389B1 (pl) 1999-05-31
MX9304819A (es) 1994-02-28
IL106624A0 (en) 1993-12-08
US5719279A (en) 1998-02-17
FI950542A (fi) 1995-02-08
CN1043348C (zh) 1999-05-12
CN1086818A (zh) 1994-05-18
RU95109100A (ru) 1996-12-27
EP0654033A1 (de) 1995-05-24
SG55038A1 (en) 1998-12-21
KR950702988A (ko) 1995-08-23
AU4707193A (en) 1994-03-03
WO1994003456A1 (de) 1994-02-17
AU681348B2 (en) 1997-08-28
CA2140883A1 (en) 1994-02-17
IL106624A (en) 1999-01-26
HUT65734A (en) 1994-07-28
NZ254804A (en) 1997-01-29
TW252044B (ar) 1995-07-21

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