BG62332B1 - Съединение с формула 4-[/2-бензотиазолил/метиламино]-алфа-[/3,4-дифлуорофенокси/метил]-1-пиперидинетанол, методи занеговото получаване и използване, както и фармацевтични състави стова съединение и методи за получаването им - Google Patents
Съединение с формула 4-[/2-бензотиазолил/метиламино]-алфа-[/3,4-дифлуорофенокси/метил]-1-пиперидинетанол, методи занеговото получаване и използване, както и фармацевтични състави стова съединение и методи за получаването им Download PDFInfo
- Publication number
- BG62332B1 BG62332B1 BG98068A BG9806893A BG62332B1 BG 62332 B1 BG62332 B1 BG 62332B1 BG 98068 A BG98068 A BG 98068A BG 9806893 A BG9806893 A BG 9806893A BG 62332 B1 BG62332 B1 BG 62332B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- formula
- compound
- preparation
- optionally
- reaction
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Epoxy Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preventing Corrosion Or Incrustation Of Metals (AREA)
- Paper (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65964591A | 1991-02-25 | 1991-02-25 | |
| PCT/EP1992/000356 WO1992014731A1 (en) | 1991-02-25 | 1992-02-14 | 4-[(2-BENZOTHIAZOLYL)METHYLAMINO]-α-[(3,4-DIFLUOROPHENOXY)METHYL]-1-PIPERIDINEETHANOL |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG98068A BG98068A (bg) | 1994-06-30 |
| BG62332B1 true BG62332B1 (bg) | 1999-08-31 |
Family
ID=24646210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG98068A BG62332B1 (bg) | 1991-02-25 | 1993-08-24 | Съединение с формула 4-[/2-бензотиазолил/метиламино]-алфа-[/3,4-дифлуорофенокси/метил]-1-пиперидинетанол, методи занеговото получаване и използване, както и фармацевтични състави стова съединение и методи за получаването им |
Country Status (36)
| Country | Link |
|---|---|
| US (2) | US5434168A (ru) |
| EP (2) | EP0573473B1 (ru) |
| JP (1) | JP2825652B2 (ru) |
| KR (1) | KR0165901B1 (ru) |
| CN (3) | CN1033454C (ru) |
| AT (1) | ATE131478T1 (ru) |
| AU (1) | AU649788B2 (ru) |
| BG (1) | BG62332B1 (ru) |
| CA (1) | CA2104000A1 (ru) |
| CY (1) | CY1924A (ru) |
| CZ (1) | CZ284705B6 (ru) |
| DE (1) | DE69206787T2 (ru) |
| DK (1) | DK0573473T3 (ru) |
| DZ (1) | DZ1560A1 (ru) |
| EE (1) | EE02983B1 (ru) |
| ES (1) | ES2083737T3 (ru) |
| FI (1) | FI933719A (ru) |
| GR (1) | GR3018692T3 (ru) |
| HK (1) | HK172296A (ru) |
| HU (2) | HUT67695A (ru) |
| IE (1) | IE69567B1 (ru) |
| IL (3) | IL100952A (ru) |
| LV (1) | LV11689B (ru) |
| MA (1) | MA22447A1 (ru) |
| MX (1) | MX9200777A (ru) |
| NO (1) | NO300591B1 (ru) |
| NZ (2) | NZ248437A (ru) |
| PL (1) | PL168791B1 (ru) |
| RO (1) | RO112959B1 (ru) |
| RU (2) | RU2094434C1 (ru) |
| SK (1) | SK278705B6 (ru) |
| TN (1) | TNSN92017A1 (ru) |
| TW (1) | TW218016B (ru) |
| WO (1) | WO1992014731A1 (ru) |
| ZA (1) | ZA921341B (ru) |
| ZW (1) | ZW1992A1 (ru) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZW1992A1 (en) * | 1991-02-25 | 1993-09-22 | Janssen Pharmaceutica Nv | 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol |
| TW282469B (ru) * | 1993-06-11 | 1996-08-01 | Janssen Pharmaceutica Nv | |
| RU2141821C1 (ru) * | 1994-10-14 | 1999-11-27 | Жансен Фармасетика Н.В. | Водная суспензия сабелюзола для орального применения и способ ее изготовления |
| HUT77390A (hu) * | 1994-11-24 | 1998-04-28 | Janssen Pharmaceutica N.V. | Lubeluzol intravénás oldatai és eljárás ezek előállítására |
| AU693354B2 (en) * | 1995-04-10 | 1998-06-25 | Baxter International Inc. | The use of cross-linked hemoglobin in treating subarachnoid hemorrhage |
| WO1997015572A1 (en) * | 1995-10-25 | 1997-05-01 | Janssen Pharmaceutica N.V. | Lubeluzole n-oxide |
| US6025355A (en) | 1997-05-19 | 2000-02-15 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
| US6242198B1 (en) | 1996-07-25 | 2001-06-05 | Cambridge Neuroscience, Inc. | Methods of treatment of eye trauma and disorders |
| US6756389B2 (en) | 1996-08-09 | 2004-06-29 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
| GB9815785D0 (en) * | 1998-07-20 | 1998-09-16 | Cerebrus Ltd | Chemical compounds |
| EP1178977B1 (en) | 1999-05-12 | 2005-06-01 | Neurosearch A/S | Ion channel modulating agents |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3963732A (en) * | 1973-05-30 | 1976-06-15 | Tiberio Bruzzese | Process for preparing dihydroxydiphenylmethane derivatives |
| US4310658A (en) * | 1980-06-18 | 1982-01-12 | Allied Corporation | Production of polyester thermally stabilized with an oxirane |
| US4861785A (en) * | 1984-12-03 | 1989-08-29 | Janssen Pharmaceutica N.V. | Benzoxazol-and benzothiazolamine derivatives, useful as anti-anoxic agents |
| CA1260474A (en) * | 1984-12-03 | 1989-09-26 | Raymond A. Stokbroekx | Benzoxazol- and benzothiazolamine derivatives |
| US4689330A (en) * | 1985-04-15 | 1987-08-25 | Janssen Pharmaceutica N.V. | Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines |
| US4749702A (en) * | 1985-04-15 | 1988-06-07 | Janssen Pharmaceutica N. V. | Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines |
| KR930005004B1 (ko) * | 1985-04-15 | 1993-06-11 | 쟈안센 파아마슈우티카 엔. 부이. | 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법 |
| US4717760A (en) * | 1986-07-10 | 1988-01-05 | The Dow Chemical Company | Fluorinated tris-epoxides based on triphenyl methane |
| JPH0643426B2 (ja) * | 1986-07-25 | 1994-06-08 | 東京田辺製薬株式会社 | イミダゾ〔４，５−ｂ〕ピリジン誘導体、その製造法及びそれを含有する抗潰瘍剤 |
| ZW1992A1 (en) * | 1991-02-25 | 1993-09-22 | Janssen Pharmaceutica Nv | 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol |
-
1992
- 1992-02-10 ZW ZW19/92A patent/ZW1992A1/xx unknown
- 1992-02-11 NZ NZ24843792A patent/NZ248437A/xx unknown
- 1992-02-11 NZ NZ24159292A patent/NZ241592A/en unknown
- 1992-02-12 CN CN92101908A patent/CN1033454C/zh not_active Expired - Fee Related
- 1992-02-14 ES ES92905117T patent/ES2083737T3/es not_active Expired - Lifetime
- 1992-02-14 PL PL92300354A patent/PL168791B1/pl unknown
- 1992-02-14 US US08/098,297 patent/US5434168A/en not_active Expired - Fee Related
- 1992-02-14 EP EP92905117A patent/EP0573473B1/en not_active Expired - Lifetime
- 1992-02-14 IL IL10095292A patent/IL100952A/en not_active IP Right Cessation
- 1992-02-14 RU RU9293053624A patent/RU2094434C1/ru active
- 1992-02-14 DE DE69206787T patent/DE69206787T2/de not_active Expired - Fee Related
- 1992-02-14 JP JP4504615A patent/JP2825652B2/ja not_active Expired - Fee Related
- 1992-02-14 CA CA002104000A patent/CA2104000A1/en not_active Abandoned
- 1992-02-14 WO PCT/EP1992/000356 patent/WO1992014731A1/en active IP Right Grant
- 1992-02-14 IL IL11383792A patent/IL113837A/en active IP Right Grant
- 1992-02-14 DK DK92905117.5T patent/DK0573473T3/da active
- 1992-02-14 HU HU9302395A patent/HUT67695A/hu unknown
- 1992-02-14 AU AU12085/92A patent/AU649788B2/en not_active Ceased
- 1992-02-14 AT AT92905117T patent/ATE131478T1/de not_active IP Right Cessation
- 1992-02-14 EP EP92200417A patent/EP0501552A1/en active Pending
- 1992-02-14 RU RU95112519/04A patent/RU2106348C1/ru not_active IP Right Cessation
- 1992-02-14 RO RO93-01147A patent/RO112959B1/ro unknown
- 1992-02-20 TW TW081101226A patent/TW218016B/zh active
- 1992-02-21 MA MA22735A patent/MA22447A1/fr unknown
- 1992-02-21 CZ CS92512A patent/CZ284705B6/cs not_active IP Right Cessation
- 1992-02-21 SK SK512-92A patent/SK278705B6/sk unknown
- 1992-02-24 MX MX9200777A patent/MX9200777A/es not_active IP Right Cessation
- 1992-02-24 DZ DZ920018A patent/DZ1560A1/fr active
- 1992-02-24 ZA ZA921341A patent/ZA921341B/xx unknown
- 1992-02-24 IE IE920575A patent/IE69567B1/en not_active IP Right Cessation
- 1992-02-25 TN TNTNSN92017A patent/TNSN92017A1/fr unknown
-
1993
- 1993-08-23 KR KR1019930702525A patent/KR0165901B1/ko not_active IP Right Cessation
- 1993-08-24 BG BG98068A patent/BG62332B1/bg unknown
- 1993-08-24 FI FI933719A patent/FI933719A/fi unknown
- 1993-08-24 NO NO933010A patent/NO300591B1/no unknown
-
1994
- 1994-11-21 EE EE9400339A patent/EE02983B1/xx unknown
-
1995
- 1995-03-24 US US08/410,549 patent/US5675027A/en not_active Expired - Fee Related
- 1995-05-24 IL IL11383795A patent/IL113837A0/xx unknown
- 1995-05-30 CN CN95105633A patent/CN1117048A/zh active Pending
- 1995-05-30 CN CN95105632A patent/CN1043609C/zh not_active Expired - Fee Related
- 1995-06-21 HU HU95P/P00319P patent/HU211560A9/hu unknown
-
1996
- 1996-01-17 GR GR960400093T patent/GR3018692T3/el unknown
- 1996-08-13 LV LVP-96-334A patent/LV11689B/en unknown
- 1996-09-12 HK HK172296A patent/HK172296A/xx not_active IP Right Cessation
-
1997
- 1997-03-07 CY CY192497A patent/CY1924A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60129210T2 (de) | Zyklische amid-derivate | |
| WO1999032481A1 (en) | Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions | |
| PL188908B1 (pl) | Nowe pochodne benzimidazolu i ich zastosowanie dowytwarzania leków do leczenia stanów alergicznych | |
| US8653069B2 (en) | Aralkyl substituted piperidine or piperazine derivatives and their use for treating schizophrenia | |
| BG62332B1 (bg) | Съединение с формула 4-[/2-бензотиазолил/метиламино]-алфа-[/3,4-дифлуорофенокси/метил]-1-пиперидинетанол, методи занеговото получаване и използване, както и фармацевтични състави стова съединение и методи за получаването им | |
| JPH10203986A (ja) | 眼疾患用薬剤 | |
| AU688186B2 (en) | (Thiophen-2-YL)-piperidin or tetrahydropyridin carboxamides | |
| CN1125065C (zh) | 苯并[g]喹啉衍生物 | |
| WO1999032486A1 (en) | Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions | |
| US5972925A (en) | Heterocyclic compounds | |
| EP0329932B1 (en) | Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments | |
| JPH05506440A (ja) | アルコキシ置換ジヒドロベンゾピラン―２―カルボン酸およびその誘導体 | |
| EP0869954B1 (en) | Heterocyclic compounds for use in the treatment of neurogenic inflammation | |
| JPH11512090A (ja) | １−（ヘテロ）アリール−４−（縮合チアゾール−２−イルアルキル）−ピペラジン誘導体、その製造方法及び５−ｈｔ▲下１ａ▼受容体介在疾患の治療におけるその使用 | |
| US5530011A (en) | 4-[(2-benzothiazolyl)methylamino]-α-[(3,4-difluorophenoxy)methyl]-1-piperidineethanol | |
| JP3092827B2 (ja) | アルケンアミド誘導体及びそのアルケンアミド誘導体を用いた抗アレルギー剤、アルケン酸、そのアルケン酸の製造方法 | |
| KR20240046553A (ko) | Sting 길항제로서의 소분자 우레아 유도체 | |
| WO1999032443A1 (en) | Muscarinic agents and use thereof to treat glaucoma, myopia, and various other conditions | |
| JPH0641079A (ja) | ピリジン誘導体 | |
| WO1999032445A1 (en) | Oximino-piperidine, -pyrrolidine and -azepine derivatives, their preparation and their use as muscarinic receptor (ant-)agonists | |
| JPH06211787A (ja) | Ｎ−フェネチルアゼピン誘導体およびその用途 | |
| JP2002515913A (ja) | 新規ヘテロ環式化合物 |