DE69206787D1 - 4-[(2-Benzothiazolyl)Methylamino]-alpha-(3,4-Difluorphenoxy)methyl-1-piperidenethanol - Google Patents
4-[(2-Benzothiazolyl)Methylamino]-alpha-(3,4-Difluorphenoxy)methyl-1-piperidenethanolInfo
- Publication number
- DE69206787D1 DE69206787D1 DE69206787T DE69206787T DE69206787D1 DE 69206787 D1 DE69206787 D1 DE 69206787D1 DE 69206787 T DE69206787 T DE 69206787T DE 69206787 T DE69206787 T DE 69206787T DE 69206787 D1 DE69206787 D1 DE 69206787D1
- Authority
- DE
- Germany
- Prior art keywords
- piperidene
- difluorophenoxy
- benzothiazolyl
- methylamino
- alpha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65964591A | 1991-02-25 | 1991-02-25 | |
PCT/EP1992/000356 WO1992014731A1 (en) | 1991-02-25 | 1992-02-14 | 4-[(2-BENZOTHIAZOLYL)METHYLAMINO]-α-[(3,4-DIFLUOROPHENOXY)METHYL]-1-PIPERIDINEETHANOL |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69206787D1 true DE69206787D1 (de) | 1996-01-25 |
DE69206787T2 DE69206787T2 (de) | 1996-06-05 |
Family
ID=24646210
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69206787T Expired - Fee Related DE69206787T2 (de) | 1991-02-25 | 1992-02-14 | 4-[(2-Benzothiazolyl)Methylamino]-alpha-(3,4-Difluorphenoxy)methyl-1-piperidenethanol |
Country Status (36)
Country | Link |
---|---|
US (2) | US5434168A (de) |
EP (2) | EP0573473B1 (de) |
JP (1) | JP2825652B2 (de) |
KR (1) | KR0165901B1 (de) |
CN (3) | CN1033454C (de) |
AT (1) | ATE131478T1 (de) |
AU (1) | AU649788B2 (de) |
BG (1) | BG62332B1 (de) |
CA (1) | CA2104000A1 (de) |
CY (1) | CY1924A (de) |
CZ (1) | CZ284705B6 (de) |
DE (1) | DE69206787T2 (de) |
DK (1) | DK0573473T3 (de) |
DZ (1) | DZ1560A1 (de) |
EE (1) | EE02983B1 (de) |
ES (1) | ES2083737T3 (de) |
FI (1) | FI933719A (de) |
GR (1) | GR3018692T3 (de) |
HK (1) | HK172296A (de) |
HU (2) | HUT67695A (de) |
IE (1) | IE69567B1 (de) |
IL (3) | IL113837A (de) |
LV (1) | LV11689B (de) |
MA (1) | MA22447A1 (de) |
MX (1) | MX9200777A (de) |
NO (1) | NO300591B1 (de) |
NZ (2) | NZ241592A (de) |
PL (1) | PL168791B1 (de) |
RO (1) | RO112959B1 (de) |
RU (2) | RU2094434C1 (de) |
SK (1) | SK278705B6 (de) |
TN (1) | TNSN92017A1 (de) |
TW (1) | TW218016B (de) |
WO (1) | WO1992014731A1 (de) |
ZA (1) | ZA921341B (de) |
ZW (1) | ZW1992A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZW1992A1 (en) * | 1991-02-25 | 1993-09-22 | Janssen Pharmaceutica Nv | 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol |
TW282469B (de) * | 1993-06-11 | 1996-08-01 | Janssen Pharmaceutica Nv | |
CN1160348A (zh) * | 1994-10-14 | 1997-09-24 | 詹森药业有限公司 | 口服沙贝鲁唑悬浮液 |
CN1166787A (zh) * | 1994-11-24 | 1997-12-03 | 詹森药业有限公司 | 用于静脉给药的鲁贝鲁唑溶液 |
EP0767675A4 (de) * | 1995-04-10 | 1998-08-05 | Baxter Int | Verwendung von vernetztem hämoglobin zur behandlung von subarachnoidalblutungen |
EP0843674A1 (de) * | 1995-10-25 | 1998-05-27 | Janssen Pharmaceutica N.V. | Lubezole n-oxide |
US6025355A (en) | 1997-05-19 | 2000-02-15 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
US6242198B1 (en) | 1996-07-25 | 2001-06-05 | Cambridge Neuroscience, Inc. | Methods of treatment of eye trauma and disorders |
US6756389B2 (en) | 1996-08-09 | 2004-06-29 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
GB9815785D0 (en) * | 1998-07-20 | 1998-09-16 | Cerebrus Ltd | Chemical compounds |
WO2000069838A1 (en) * | 1999-05-12 | 2000-11-23 | Neurosearch A/S | Ion channel modulating agents |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3963732A (en) * | 1973-05-30 | 1976-06-15 | Tiberio Bruzzese | Process for preparing dihydroxydiphenylmethane derivatives |
US4310658A (en) * | 1980-06-18 | 1982-01-12 | Allied Corporation | Production of polyester thermally stabilized with an oxirane |
US4861785A (en) * | 1984-12-03 | 1989-08-29 | Janssen Pharmaceutica N.V. | Benzoxazol-and benzothiazolamine derivatives, useful as anti-anoxic agents |
CA1260474A (en) * | 1984-12-03 | 1989-09-26 | Raymond A. Stokbroekx | Benzoxazol- and benzothiazolamine derivatives |
US4689330A (en) * | 1985-04-15 | 1987-08-25 | Janssen Pharmaceutica N.V. | Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines |
US4749702A (en) * | 1985-04-15 | 1988-06-07 | Janssen Pharmaceutica N. V. | Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines |
KR930005004B1 (ko) * | 1985-04-15 | 1993-06-11 | 쟈안센 파아마슈우티카 엔. 부이. | 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법 |
US4717760A (en) * | 1986-07-10 | 1988-01-05 | The Dow Chemical Company | Fluorinated tris-epoxides based on triphenyl methane |
JPH0643426B2 (ja) * | 1986-07-25 | 1994-06-08 | 東京田辺製薬株式会社 | イミダゾ〔4,5−b〕ピリジン誘導体、その製造法及びそれを含有する抗潰瘍剤 |
ZW1992A1 (en) * | 1991-02-25 | 1993-09-22 | Janssen Pharmaceutica Nv | 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol |
-
1992
- 1992-02-10 ZW ZW19/92A patent/ZW1992A1/xx unknown
- 1992-02-11 NZ NZ24159292A patent/NZ241592A/en unknown
- 1992-02-11 NZ NZ24843792A patent/NZ248437A/xx unknown
- 1992-02-12 CN CN92101908A patent/CN1033454C/zh not_active Expired - Fee Related
- 1992-02-14 HU HU9302395A patent/HUT67695A/hu unknown
- 1992-02-14 PL PL92300354A patent/PL168791B1/pl unknown
- 1992-02-14 AT AT92905117T patent/ATE131478T1/de not_active IP Right Cessation
- 1992-02-14 AU AU12085/92A patent/AU649788B2/en not_active Ceased
- 1992-02-14 DK DK92905117.5T patent/DK0573473T3/da active
- 1992-02-14 RU RU9293053624A patent/RU2094434C1/ru active
- 1992-02-14 RU RU95112519/04A patent/RU2106348C1/ru not_active IP Right Cessation
- 1992-02-14 US US08/098,297 patent/US5434168A/en not_active Expired - Fee Related
- 1992-02-14 DE DE69206787T patent/DE69206787T2/de not_active Expired - Fee Related
- 1992-02-14 WO PCT/EP1992/000356 patent/WO1992014731A1/en active IP Right Grant
- 1992-02-14 CA CA002104000A patent/CA2104000A1/en not_active Abandoned
- 1992-02-14 IL IL11383792A patent/IL113837A/en active IP Right Grant
- 1992-02-14 JP JP4504615A patent/JP2825652B2/ja not_active Expired - Fee Related
- 1992-02-14 ES ES92905117T patent/ES2083737T3/es not_active Expired - Lifetime
- 1992-02-14 EP EP92905117A patent/EP0573473B1/de not_active Expired - Lifetime
- 1992-02-14 EP EP92200417A patent/EP0501552A1/de active Pending
- 1992-02-14 RO RO93-01147A patent/RO112959B1/ro unknown
- 1992-02-14 IL IL10095292A patent/IL100952A/en not_active IP Right Cessation
- 1992-02-20 TW TW081101226A patent/TW218016B/zh active
- 1992-02-21 MA MA22735A patent/MA22447A1/fr unknown
- 1992-02-21 SK SK512-92A patent/SK278705B6/sk unknown
- 1992-02-21 CZ CS92512A patent/CZ284705B6/cs not_active IP Right Cessation
- 1992-02-24 ZA ZA921341A patent/ZA921341B/xx unknown
- 1992-02-24 MX MX9200777A patent/MX9200777A/es not_active IP Right Cessation
- 1992-02-24 DZ DZ920018A patent/DZ1560A1/fr active
- 1992-02-24 IE IE920575A patent/IE69567B1/en not_active IP Right Cessation
- 1992-02-25 TN TNTNSN92017A patent/TNSN92017A1/fr unknown
-
1993
- 1993-08-23 KR KR1019930702525A patent/KR0165901B1/ko not_active IP Right Cessation
- 1993-08-24 BG BG98068A patent/BG62332B1/bg unknown
- 1993-08-24 FI FI933719A patent/FI933719A/fi unknown
- 1993-08-24 NO NO933010A patent/NO300591B1/no unknown
-
1994
- 1994-11-21 EE EE9400339A patent/EE02983B1/xx unknown
-
1995
- 1995-03-24 US US08/410,549 patent/US5675027A/en not_active Expired - Fee Related
- 1995-05-24 IL IL11383795A patent/IL113837A0/xx unknown
- 1995-05-30 CN CN95105632A patent/CN1043609C/zh not_active Expired - Fee Related
- 1995-05-30 CN CN95105633A patent/CN1117048A/zh active Pending
- 1995-06-21 HU HU95P/P00319P patent/HU211560A9/hu unknown
-
1996
- 1996-01-17 GR GR960400093T patent/GR3018692T3/el unknown
- 1996-08-13 LV LVP-96-334A patent/LV11689B/en unknown
- 1996-09-12 HK HK172296A patent/HK172296A/xx not_active IP Right Cessation
-
1997
- 1997-03-07 CY CY192497A patent/CY1924A/xx unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |