BG61484B1 - 3'-(2')-амино-и тиолмодифицирани, свързани с флуоресциращо багрило нуклеозиди,нуклеотиди и олигонуклеотиди и метод за тяхното получаване и приложението им - Google Patents

3'-(2')-амино-и тиолмодифицирани, свързани с флуоресциращо багрило нуклеозиди,нуклеотиди и олигонуклеотиди и метод за тяхното получаване и приложението им Download PDF

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Publication number
BG61484B1
BG61484B1 BG95575A BG9557591A BG61484B1 BG 61484 B1 BG61484 B1 BG 61484B1 BG 95575 A BG95575 A BG 95575A BG 9557591 A BG9557591 A BG 9557591A BG 61484 B1 BG61484 B1 BG 61484B1
Authority
BG
Bulgaria
Prior art keywords
group
amino
synthesis
formula
oligonucleotides
Prior art date
Application number
BG95575A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG95575A (bg
Inventor
Joachim Engels
Mathias Herrlein
Renate Konrad
Matthias Mag
Original Assignee
Hoechst Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Aktiengesellschaft filed Critical Hoechst Aktiengesellschaft
Publication of BG95575A publication Critical patent/BG95575A/bg
Publication of BG61484B1 publication Critical patent/BG61484B1/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG95575A 1990-12-11 1991-12-04 3'-(2')-амино-и тиолмодифицирани, свързани с флуоресциращо багрило нуклеозиди,нуклеотиди и олигонуклеотиди и метод за тяхното получаване и приложението им BG61484B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4039488 1990-12-11

Publications (2)

Publication Number Publication Date
BG95575A BG95575A (bg) 1993-12-24
BG61484B1 true BG61484B1 (bg) 1997-09-30

Family

ID=6420050

Family Applications (1)

Application Number Title Priority Date Filing Date
BG95575A BG61484B1 (bg) 1990-12-11 1991-12-04 3'-(2')-амино-и тиолмодифицирани, свързани с флуоресциращо багрило нуклеозиди,нуклеотиди и олигонуклеотиди и метод за тяхното получаване и приложението им

Country Status (27)

Country Link
US (3) US5679785A (ko)
EP (1) EP0490281B1 (ko)
JP (1) JP3140127B2 (ko)
KR (1) KR920012107A (ko)
AT (1) ATE142222T1 (ko)
AU (1) AU643856B2 (ko)
BG (1) BG61484B1 (ko)
BR (1) BR9105335A (ko)
CA (1) CA2057475A1 (ko)
CS (1) CS374391A3 (ko)
DE (1) DE59108143D1 (ko)
DK (1) DK0490281T3 (ko)
ES (1) ES2093671T3 (ko)
FI (1) FI915779A (ko)
GR (1) GR3021041T3 (ko)
HU (1) HUT60505A (ko)
IE (1) IE75726B1 (ko)
IL (1) IL100298A (ko)
MX (1) MX9102468A (ko)
NO (1) NO914859L (ko)
NZ (1) NZ240900A (ko)
PL (1) PL168874B1 (ko)
PT (1) PT99747A (ko)
RO (1) RO111575B1 (ko)
RU (1) RU2073682C1 (ko)
TR (1) TR27715A (ko)
YU (1) YU187991A (ko)

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JP4177123B2 (ja) * 2003-01-10 2008-11-05 富士通株式会社 配線図形検証方法、プログラム及び装置
ES2524048T3 (es) 2003-03-31 2014-12-03 F. Hoffmann-La Roche Ag Composiciones y métodos para la detección de ciertos flavivirus, incluidos los miembros del serogrupo del virus de la encefalitis japonesa
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US7160537B2 (en) * 2003-12-15 2007-01-09 Siemens Medical Solutions Usa, Inc. Method for preparing radiolabeled thymidine having low chromophoric byproducts
US7939251B2 (en) 2004-05-06 2011-05-10 Roche Molecular Systems, Inc. SENP1 as a marker for cancer
US20060172133A1 (en) * 2004-08-17 2006-08-03 Imad Naasani Synthesis of highly luminescent colloidal particles
ATE556126T1 (de) 2004-10-29 2012-05-15 Life Technologies Corp Funktionalisierte fluoreszierende nanokristalle und verfahren zu deren herstellung und verwendung
EP1809765A2 (en) * 2004-11-04 2007-07-25 Roche Diagnostics GmbH Classification of acute myeloid leukemia
US7541144B2 (en) * 2005-01-31 2009-06-02 Agilent Technologies, Inc. RNA labeling method
US20080003571A1 (en) 2005-02-01 2008-01-03 Mckernan Kevin Reagents, methods, and libraries for bead-based sequencing
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US8431416B2 (en) 2009-04-01 2013-04-30 Becton, Dickinson And Company Reactive heterocycle-substituted 7-hydroxycoumarins and their conjugates
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ES2647612T3 (es) 2010-06-04 2017-12-22 Chronix Biomedical Biomarcadores de ácidos nucleicos en circulación asociados al cáncer de próstata
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Also Published As

Publication number Publication date
TR27715A (tr) 1995-06-22
ES2093671T3 (es) 1997-01-01
RO111575B1 (ro) 1996-11-29
YU187991A (sh) 1994-09-09
PL168874B1 (pl) 1996-04-30
DK0490281T3 (ko) 1997-02-10
EP0490281A1 (de) 1992-06-17
PL292701A1 (en) 1992-09-21
NO914859L (no) 1992-06-12
GR3021041T3 (en) 1996-12-31
FI915779A0 (fi) 1991-12-09
BR9105335A (pt) 1992-08-25
IE914301A1 (en) 1992-06-17
HUT60505A (en) 1992-09-28
JP3140127B2 (ja) 2001-03-05
RU2073682C1 (ru) 1997-02-20
ATE142222T1 (de) 1996-09-15
JPH04290896A (ja) 1992-10-15
IE75726B1 (en) 1997-09-24
KR920012107A (ko) 1992-07-25
NO914859D0 (no) 1991-12-10
US5668269A (en) 1997-09-16
US5659025A (en) 1997-08-19
US5679785A (en) 1997-10-21
MX9102468A (es) 1992-06-01
FI915779A (fi) 1992-06-12
DE59108143D1 (de) 1996-10-10
EP0490281B1 (de) 1996-09-04
HU913885D0 (en) 1992-02-28
BG95575A (bg) 1993-12-24
PT99747A (pt) 1992-11-30
IL100298A (en) 1997-03-18
AU8892791A (en) 1992-06-18
IL100298A0 (en) 1992-09-06
AU643856B2 (en) 1993-11-25
NZ240900A (en) 1994-07-26
CS374391A3 (en) 1992-06-17
CA2057475A1 (en) 1992-06-12

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