BR9105335A - Nucleosidios,nucleotideos e oligonucleotideos 3'-e/ou 2'-amino-e tiol-modificados,processo para a sua obtencao e sua aplicacao - Google Patents

Nucleosidios,nucleotideos e oligonucleotideos 3'-e/ou 2'-amino-e tiol-modificados,processo para a sua obtencao e sua aplicacao

Info

Publication number
BR9105335A
BR9105335A BR919105335A BR9105335A BR9105335A BR 9105335 A BR9105335 A BR 9105335A BR 919105335 A BR919105335 A BR 919105335A BR 9105335 A BR9105335 A BR 9105335A BR 9105335 A BR9105335 A BR 9105335A
Authority
BR
Brazil
Prior art keywords
amino
synthesis
modified
oligonucleotideos
nucleotideos
Prior art date
Application number
BR919105335A
Other languages
English (en)
Inventor
Joachim Engels
Mathias Herrlein
Renate Konrad
Matthias Mag
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of BR9105335A publication Critical patent/BR9105335A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
BR919105335A 1990-12-11 1991-12-11 Nucleosidios,nucleotideos e oligonucleotideos 3'-e/ou 2'-amino-e tiol-modificados,processo para a sua obtencao e sua aplicacao BR9105335A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4039488 1990-12-11

Publications (1)

Publication Number Publication Date
BR9105335A true BR9105335A (pt) 1992-08-25

Family

ID=6420050

Family Applications (1)

Application Number Title Priority Date Filing Date
BR919105335A BR9105335A (pt) 1990-12-11 1991-12-11 Nucleosidios,nucleotideos e oligonucleotideos 3'-e/ou 2'-amino-e tiol-modificados,processo para a sua obtencao e sua aplicacao

Country Status (27)

Country Link
US (3) US5679785A (pt)
EP (1) EP0490281B1 (pt)
JP (1) JP3140127B2 (pt)
KR (1) KR920012107A (pt)
AT (1) ATE142222T1 (pt)
AU (1) AU643856B2 (pt)
BG (1) BG61484B1 (pt)
BR (1) BR9105335A (pt)
CA (1) CA2057475A1 (pt)
CS (1) CS374391A3 (pt)
DE (1) DE59108143D1 (pt)
DK (1) DK0490281T3 (pt)
ES (1) ES2093671T3 (pt)
FI (1) FI915779A (pt)
GR (1) GR3021041T3 (pt)
HU (1) HUT60505A (pt)
IE (1) IE75726B1 (pt)
IL (1) IL100298A (pt)
MX (1) MX9102468A (pt)
NO (1) NO914859L (pt)
NZ (1) NZ240900A (pt)
PL (1) PL168874B1 (pt)
PT (1) PT99747A (pt)
RO (1) RO111575B1 (pt)
RU (1) RU2073682C1 (pt)
TR (1) TR27715A (pt)
YU (1) YU187991A (pt)

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US20050032081A1 (en) * 2002-12-13 2005-02-10 Jingyue Ju Biomolecular coupling methods using 1,3-dipolar cycloaddition chemistry
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US20050131224A1 (en) * 2003-12-15 2005-06-16 Cti Pet Systems, Inc. Method for preparing radiolabeled thymidine
US7160537B2 (en) * 2003-12-15 2007-01-09 Siemens Medical Solutions Usa, Inc. Method for preparing radiolabeled thymidine having low chromophoric byproducts
US7939251B2 (en) 2004-05-06 2011-05-10 Roche Molecular Systems, Inc. SENP1 as a marker for cancer
JP2008510852A (ja) * 2004-08-17 2008-04-10 インヴィトロジェン コーポレーション 高発光性コロイド粒子の合成
WO2007001438A2 (en) 2004-10-29 2007-01-04 Molecular Probes, Inc. Functionalized fluorescent nanocrystals, and methods for their preparation and use
EP1809765A2 (en) * 2004-11-04 2007-07-25 Roche Diagnostics GmbH Classification of acute myeloid leukemia
US7541144B2 (en) * 2005-01-31 2009-06-02 Agilent Technologies, Inc. RNA labeling method
EP2003214B1 (en) 2005-02-01 2013-04-10 AB Advanced Genetic Analysis Corporation Reagents, methods, and libraries for bead-based sequencing
US7544471B2 (en) * 2005-07-30 2009-06-09 Agilent Technologies, Inc. Preparing RNA from a wax-embedded tissue specimen
US7700289B2 (en) * 2006-04-03 2010-04-20 Agilent Technologies, Inc. Method for labeling RNA
US20090062129A1 (en) * 2006-04-19 2009-03-05 Agencourt Personal Genomics, Inc. Reagents, methods, and libraries for gel-free bead-based sequencing
US7572585B2 (en) * 2006-07-31 2009-08-11 Agilent Technologies, Inc. Enzymatic labeling of RNA
BRPI0719923B1 (pt) * 2006-12-05 2021-08-17 Agilent Technologies Inc Métodos para sequenciamento de um ácido nucléico alvo, para conversão de um componente de ocorrência não natural em uma molécula de ácido nucléico em um componente de ocorrência natural, para terminar uma síntese de ácido nucléico, e para realizar o sequenciamento de sanger ou tipo sanger, e compostos
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ES2413566B1 (es) 2011-12-14 2014-05-20 Fundación Pública Andaluza Progreso Y Salud Método de obtención de datos útiles para el diagnóstico y pronóstico de la hipoacusia neurosensorial.
JP6181751B2 (ja) 2012-06-18 2017-08-16 ニューゲン テクノロジーズ， インコーポレイテッド 望まれない核酸配列のネガティブ選択のための組成物および方法
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EP3201361B1 (en) 2014-10-01 2020-02-12 Chronix Biomedical Methods of quantifying cell-free dna
JP2019512573A (ja) 2016-03-28 2019-05-16 エーエーティー バイオクエスト インコーポレイテッド ポリフルオレノ［４，５−ｃｄｅ］オキセピンコンジュゲート及び分析物検出方法におけるそれらの使用
US11220628B2 (en) 2019-02-20 2022-01-11 Aat Bioquest, Inc. Condensed polycyclic conjugated polymers and their use for biological detection
CN115280147A (zh) 2020-01-30 2022-11-01 阿特生物探索公司 可紫外激发的基于聚芴的缀合物及其在分析物检测方法中的用途
WO2023147355A2 (en) * 2022-01-25 2023-08-03 Oregon Health & Science University Methods and systems for increasing capture potential of a spatial array

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US4849513A (en) * 1983-12-20 1989-07-18 California Institute Of Technology Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups
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Also Published As

Publication number Publication date
NZ240900A (en) 1994-07-26
KR920012107A (ko) 1992-07-25
EP0490281B1 (de) 1996-09-04
GR3021041T3 (en) 1996-12-31
ES2093671T3 (es) 1997-01-01
AU643856B2 (en) 1993-11-25
MX9102468A (es) 1992-06-01
NO914859D0 (no) 1991-12-10
TR27715A (tr) 1995-06-22
PL168874B1 (pl) 1996-04-30
IL100298A0 (en) 1992-09-06
PT99747A (pt) 1992-11-30
CS374391A3 (en) 1992-06-17
FI915779A0 (fi) 1991-12-09
JPH04290896A (ja) 1992-10-15
PL292701A1 (en) 1992-09-21
YU187991A (sh) 1994-09-09
US5679785A (en) 1997-10-21
IL100298A (en) 1997-03-18
IE75726B1 (en) 1997-09-24
JP3140127B2 (ja) 2001-03-05
ATE142222T1 (de) 1996-09-15
RU2073682C1 (ru) 1997-02-20
NO914859L (no) 1992-06-12
US5659025A (en) 1997-08-19
EP0490281A1 (de) 1992-06-17
HU913885D0 (en) 1992-02-28
HUT60505A (en) 1992-09-28
DE59108143D1 (de) 1996-10-10
BG61484B1 (bg) 1997-09-30
DK0490281T3 (pt) 1997-02-10
US5668269A (en) 1997-09-16
RO111575B1 (ro) 1996-11-29
FI915779A (fi) 1992-06-12
IE914301A1 (en) 1992-06-17
CA2057475A1 (en) 1992-06-12
AU8892791A (en) 1992-06-18

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