DE69627698D1 - Eine in kaskaden verlaufende vervielfältigungsreaktion von nukleinsäuren - Google Patents

Eine in kaskaden verlaufende vervielfältigungsreaktion von nukleinsäuren

Info

Publication number
DE69627698D1
DE69627698D1 DE69627698T DE69627698T DE69627698D1 DE 69627698 D1 DE69627698 D1 DE 69627698D1 DE 69627698 T DE69627698 T DE 69627698T DE 69627698 T DE69627698 T DE 69627698T DE 69627698 D1 DE69627698 D1 DE 69627698D1
Authority
DE
Germany
Prior art keywords
oligonucleotide
nucleic acid
cascades
circular
acid replacement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69627698T
Other languages
English (en)
Other versions
DE69627698T2 (de
Inventor
Jorn Erland Koch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olink AB
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69627698D1 publication Critical patent/DE69627698D1/de
Publication of DE69627698T2 publication Critical patent/DE69627698T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
DE69627698T 1995-12-05 1996-12-05 Eine in kaskaden verlaufende vervielfältigungsreaktion von nukleinsäuren Expired - Lifetime DE69627698T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK137995 1995-12-05
PCT/DK1996/000513 WO1997020948A1 (en) 1995-12-05 1996-12-05 A cascade nucleic acid amplification reaction

Publications (2)

Publication Number Publication Date
DE69627698D1 true DE69627698D1 (de) 2003-05-28
DE69627698T2 DE69627698T2 (de) 2004-01-15

Family

ID=8104224

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69636080T Expired - Lifetime DE69636080T2 (de) 1995-12-05 1996-12-05 Eine in Kaskaden verlaufende Vervielfältigungsreaktion von Nukleinsäuren
DE69627698T Expired - Lifetime DE69627698T2 (de) 1995-12-05 1996-12-05 Eine in kaskaden verlaufende vervielfältigungsreaktion von nukleinsäuren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69636080T Expired - Lifetime DE69636080T2 (de) 1995-12-05 1996-12-05 Eine in Kaskaden verlaufende Vervielfältigungsreaktion von Nukleinsäuren

Country Status (9)

Country Link
US (1) US6610481B2 (de)
EP (2) EP0868530B1 (de)
AT (2) ATE324464T1 (de)
AU (1) AU704750B2 (de)
CA (1) CA2239287C (de)
DE (2) DE69636080T2 (de)
DK (2) DK0868530T3 (de)
ES (1) ES2262902T3 (de)
WO (1) WO1997020948A1 (de)

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WO2004048596A2 (en) 2002-11-21 2004-06-10 Epicentre Technologies Methods for using primers that encode one strand of a double-stranded promoter
US9487823B2 (en) 2002-12-20 2016-11-08 Qiagen Gmbh Nucleic acid amplification
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US8080393B2 (en) 2005-04-12 2011-12-20 Olink Ab Methods for production of oligonucleotides
CA2611743C (en) 2005-06-15 2019-12-31 Callida Genomics, Inc. Nucleic acid analysis by forming and tracking aliquoted fragments of a target polynucleotide
EP1762627A1 (de) 2005-09-09 2007-03-14 Qiagen GmbH Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
EP1934339B1 (de) 2005-10-06 2011-12-14 Lucigen Corporation Temperaturstabile virale polymerasen und verwendungsverfahren
AU2007249635B2 (en) 2005-10-07 2012-05-31 Complete Genomics, Inc. High throughput genome sequencing on DNA arrays
US7960104B2 (en) * 2005-10-07 2011-06-14 Callida Genomics, Inc. Self-assembled single molecule arrays and uses thereof
US20070168197A1 (en) * 2006-01-18 2007-07-19 Nokia Corporation Audio coding
SG170028A1 (en) * 2006-02-24 2011-04-29 Callida Genomics Inc High throughput genome sequencing on dna arrays
GB0621361D0 (en) * 2006-10-26 2006-12-06 Fermentas Uab Use of DNA polymerases
WO2008070352A2 (en) 2006-10-27 2008-06-12 Complete Genomics, Inc. Efficient arrays of amplified polynucleotides
US20090105961A1 (en) * 2006-11-09 2009-04-23 Complete Genomics, Inc. Methods of nucleic acid identification in large-scale sequencing
US20090111705A1 (en) 2006-11-09 2009-04-30 Complete Genomics, Inc. Selection of dna adaptor orientation by hybrid capture
RU2414510C2 (ru) * 2007-06-14 2011-03-20 Институт биохимии и генетики Уфимского научного центра РАН Способ амплификации специфичных фрагментов нуклеиновых кислот с помощью рекуррентной цепной реакции
US8518640B2 (en) * 2007-10-29 2013-08-27 Complete Genomics, Inc. Nucleic acid sequencing and process
US8617811B2 (en) 2008-01-28 2013-12-31 Complete Genomics, Inc. Methods and compositions for efficient base calling in sequencing reactions
US20090263872A1 (en) * 2008-01-23 2009-10-22 Complete Genomics Inc. Methods and compositions for preventing bias in amplification and sequencing reactions
US7901890B2 (en) * 2007-11-05 2011-03-08 Complete Genomics, Inc. Methods and oligonucleotide designs for insertion of multiple adaptors employing selective methylation
US8415099B2 (en) 2007-11-05 2013-04-09 Complete Genomics, Inc. Efficient base determination in sequencing reactions
US7897344B2 (en) * 2007-11-06 2011-03-01 Complete Genomics, Inc. Methods and oligonucleotide designs for insertion of multiple adaptors into library constructs
WO2009073629A2 (en) 2007-11-29 2009-06-11 Complete Genomics, Inc. Efficient shotgun sequencing methods
US8592150B2 (en) 2007-12-05 2013-11-26 Complete Genomics, Inc. Methods and compositions for long fragment read sequencing
US20090270273A1 (en) * 2008-04-21 2009-10-29 Complete Genomics, Inc. Array structures for nucleic acid detection
US9524369B2 (en) 2009-06-15 2016-12-20 Complete Genomics, Inc. Processing and analysis of complex nucleic acid sequence data
CN103649331A (zh) 2011-02-15 2014-03-19 莱卡生物系统纽卡斯尔有限责任公司 用于mrna的定位的原位检测的方法
US9556473B2 (en) 2011-02-15 2017-01-31 Leica Biosystems Newcastle Ltd Methods for identifying nucleic acid sequences
WO2012170936A2 (en) 2011-06-09 2012-12-13 Illumina, Inc. Patterned flow-cells useful for nucleic acid analysis
US8778849B2 (en) 2011-10-28 2014-07-15 Illumina, Inc. Microarray fabrication system and method
CN104955963A (zh) 2012-11-14 2015-09-30 欧凌科公司 Rca报告探针及其用于检测核酸分子的用途
CN104919057B (zh) 2012-11-14 2018-09-25 欧凌科公司 基于rca的局部扩增方法
GB201320145D0 (en) 2013-11-14 2014-01-01 Olink Ab Localised RCA-based amplification method using a padlock-probe
CA3219413A1 (en) 2014-05-16 2015-11-19 Illumina, Inc. Nucleic acid synthesis techniques
WO2016103234A1 (en) * 2014-12-24 2016-06-30 Abbott Japan Co., Ltd. Detection method based on signal amplifier dna cascade reactions with target extension
GB201614023D0 (en) 2016-08-16 2016-09-28 Olink Bioscience Ab Double-stranded circle probes
AU2017370751B2 (en) 2016-12-09 2023-11-09 Ultivue, Inc. Improved methods for multiplex imaging using labeled nucleic acid imaging agents
CN110446719B (zh) 2017-03-31 2023-10-03 乌尔蒂维尤股份有限公司 Dna-抗原交换和扩增

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Also Published As

Publication number Publication date
DE69636080D1 (de) 2006-06-01
ATE324464T1 (de) 2006-05-15
EP1300466B1 (de) 2006-04-26
WO1997020948A1 (en) 1997-06-12
EP1300466A3 (de) 2004-01-02
EP0868530A1 (de) 1998-10-07
ATE238434T1 (de) 2003-05-15
DE69636080T2 (de) 2006-11-30
AU7691796A (en) 1997-06-27
DE69627698T2 (de) 2004-01-15
CA2239287A1 (en) 1997-06-12
ES2262902T3 (es) 2006-12-01
DK0868530T3 (da) 2003-07-21
CA2239287C (en) 2008-02-26
US20020031764A1 (en) 2002-03-14
AU704750B2 (en) 1999-05-06
DK1300466T3 (da) 2006-08-28
EP0868530B1 (de) 2003-04-23
US6610481B2 (en) 2003-08-26
EP1300466A2 (de) 2003-04-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: IN SITU RCP A/S, AALBORG, DK

8381 Inventor (new situation)

Inventor name: KOCH, ERLAND, JORN, 8382 HINNERUP, DK

8327 Change in the person/name/address of the patent owner

Owner name: OLINK AB, UPPSALA, SE